Traditional Chinese Medicine (TCM), as a treasure of the Chinese nation, plays a significant role in maintaining public health. In 2019, the Central Committee of the Communist Party of China and the State Council proposed for the first time the establishment of a TCM registration and evaluation evidence system that integrates TCM theory, "personal experience" and clinical trials (referred to as the "Three-in-One" System) to promote the inheritance and innovation of TCM. Subsequently, the National Medical Products Administration issued several guiding principles to advance the improvement and implementation of this system. Owing to the complexity of its implementation, there are still differing understandings within the TCM industry regarding the positioning of the "Three-in-One" Registration and Evaluation Evidence System, as well as the connotation and value orientation of the "personal experience." To address this, Academician WANG Qi, President of the TCM Association, China International Exchange and Promotion Association for Medical and Healthcare and TCM master, led a group of academicians, TCM masters, TCM pharmacology experts and clinical TCM experts to convene a "Seminar on Promoting the Implementation of the ′Three-in-One′ Registration and Evaluation Evidence System for Chinese Medicinals." Through extensive discussions, an expert consensus was formed, clarifying the different roles of the TCM theory, "personal experience" and clinical trials within the system. It was further emphasized that the "personal experience" is the core of this system, and its data should be derived from clinical practice scenarios. In the future, the improvement of this system will require collaborative efforts across multiple fields to promote the high-quality development of the Chinese medicinal industry.

Objective To compare the clinical effect of first-line chemotherapy containing oxaliplatin on left and right colon cancer.Methods A total of 120 patients with colon cancer admitted to Second Affiliated Hospital of Shanghai University from January 2020 to January 2024 were selected and divided into left colon cancer group(60 cases)and right colon cancer group(60 cases)according to tumor location.Both groups were treated with first-line chemotherapy containing oxaliplatin for 2 cycles.Disease control rate,serum tumor markers,serum inflammatory factors,cancer-causing symptom scores,quality of life and incidence of adverse reactions were compared between two groups.Results After treatment,disease control rate in left colon cancer group was significantly higher than that in right colon cancer group(x2=22.224,P＜0.00 1).The levels of serum carcinoembryonic antigen,carbohydrate antigen 125,carbohydrate antigen 153,C-reactive protein and interleukin-6 of left colon cancer group were lower than those of right colon cancer group(P＜0.05).The scores of cancer-related pain and fatigue of left colon cancer group were lower than those of right colon cancer group(P＜0.05).The quality of life in left colon cancer group was better than that in right colon cancer group(P＜0.05).Conclusion First-line chemotherapy containing oxaliplatin has better short-term efficacy in patients with left colon cancer,with better control of tumor progression,and can improre clinical symptoms and quality of life.

It is significant to enhance the doctor-patient communication ability for medical graduates during clinical practice stage and establish appropriate doctor-patient communication sense,which is also important to promote medical education quality and cultivate qualified medical talents.This paper analyzed the common problems in doctor-patient communication for medical graduates.For example,patients did not trust the intern students;the students were nervous when faced with patients;some did not pay attention to their images;some called patients improperly.Then,it put forward some measures:to set up the communication and training courses,to carry out the communication skill training in clinical practice,and to attach importance to the doctor-patient communication skill practice.

Objective To study the diagnostic value of repetitive nerve stimulation test in myasthenia gravis. Method The repetitive nerve stimulation test was performed at axillary nerves, ulnar nerves and facial nerves in 36 patients with myasthenia gravis which treated in our hospital from 1996. 10 to 1999. 10. 108 nerves were tested. Result The RNS test positivity rate of amplitude decrement in 108 nerves was 60. 2% ( 65 nerves). Among them, the highest(77. 8% )positivity rate was deltoid mucle supported by axillary nerve, the lowest(41.7% ) was abductor digiti minimi mucle supported by ulnar nerve. There were 31 cases(86. 1% ) had one or more than one nerves with positive results in 36 patients. The best stimulation frequancy were 3 ～ 5 Hz. Conclusion Stimulate the axillary nerve, facial nerve and ulnar nerve in the same patient, would improve the RNS positivity rate in diagnosis of MG.