Objective To investigate the relationship of skin failure (SF) with nutritional status in elderly critically ill patients and analyze the predictive efficiency of nutritional status on SF. Methods A total of 340 elderly critically ill patients admitted to the hospital from January 2020 to January 2025 were selected as research subjects. According to whether skin failure occurred, the above patients were classified into skin failure group and non-skin failure group. The nutritional status indicators [serum albumin (ALB), prealbumin (PA), total protein (TP), hemoglobin (Hb), body mass index (BMI), nutritional risk score (NRS 2002)] were compared between both groups. Multivariate analysis was performed on statistically significant indicators, and ROC curve was applied to analyze the predictive value. Results Among the 340 elderly critically ill patients, 142 cases (41.76%) developed skin failure. The ALB, PA, TP, Hb and BMI in the skin failure group were lower than those in the non-skin failure group (P<0.05) while the NRS2002 score was higher (P<0.05). After logistic multivariate analysis, ALB, PA and Hb were independent influencing factors of skin failure (P<0.05). ROC curve analysis revealed that the predictive value of ALB (AUC=0.850, 95%CI: 0.808-0.888, Z=-3.707, P<0.001) was better than that of PA (AUC=0.770, 95%CI: 0.717-0.816, Z=-3.100, P=0.002) or Hb (AUC=0.773, 95%CI: 0.722-0.819, Z=-2.556, P=0.011). Conclusion The occurrence of skin failure in elderly critically ill patients is closely related to nutritional status. ALB, PA and Hb are independent risk factors of SF, and ALB has the best predictive efficiency on SF.

1. The frontal sinuses of 250 skulls of Chinese male adults were investigated. Ac-cording to the number of the frontal sinuses, the skulls were classified into five types. Type Ⅰ. no frontal sinus. Type Ⅱ. one frontal sinus (either left or right). Type Ⅲ. two frontal sinuses (one on each side). Type Ⅳ. three frontal sinuses (two left, one right, & vice versa). TyPe Ⅴ. four frontal sinuses (two on each side). 2. The degrees of superior, lateral and posterior extensions of the frontal sinuses inmost cases were grossly symmetrical. 3. It was found that two frontal sinuses were extended posteriorly over the orbitto near the greater and lesser wings of the sphenoid bone. 4. The degree of prominence of the superciliary arches was neither the indicationof the presence of the frontal sinuses nor the estimation of its extension or size. 5. The thickness of the anterior wall of the frontal sinuses was within 0.8--3 mm(89.4% on the left, 84.6% on the right), and the thickness of its septum fluctuated be-tween 0.1--2 mm (70.4%). The septa of all metopic skulls were divided into two partsby the suture. 6. The invading cells and the recesses of the frontal sinuses were studied, classifiedand discussed. 7. The position of the openings of the naso-frontal duct was as follows: 1. drain-age into the ethmoid infundibulum 49.5%. 2. drainage into the frontal recess 26.2%. 3.drainage into the frontal pit 20.5%. 4. drainage into the supra-bulla region 3.8%.

The blood vessels of the adrenal gland of 28 fetuses and newborns were studied in this work. Three methods, the injection replication of the microvasculature for scanning electron microscopy, the injection of ink for light microscope and lead latex injection for gross anatomy, have been used. The superior, middle and inferior arteries of the adrenal gland originate from the inferior phrenic artery, abdominal aorta and renal artery respectively. They branch into fin- er arteries when they reach the surface of the gland and run through the capsule of the gland. The finer arteries divide into branches beneath the capsula of the gland. Some of the ultimate branches divide into capillaries and form the subcapsular plexus proper. Others enter directly into the adrenal cortex and medulla separately. They are named the cortical arteries and medullary arteries. Looped cortical arteries run into the cortex from subcapsular plexus, and return to the subcapsular plexus and supply it with blood. We call them the "V" type arteries. The subcapsular plexus gives off numerous capillaries that form the adult cortical capillary plexus which supplies, in turn, the fetal cortex capillaries with blood. The cortical arteries give off the capillaries to supply blood to the fetal cortex. These two kinds of the capillaries form the fetal cortical capillary plexus. In the middle of the fetal cortex the capillaries converge into small veins which run centripetally. Some of them form the first order branch of the central vein. Others break up into the capillaries near the central region. These capillaries converge into the small venous channels which drain into the central vein. This form of vessels is named the "portal vessels". Medullary cells migrating in the cortex are supplied with blood by the medullary arteries proper. The small veins converge gradually to form a treelike pattern and finally drain into the central vein which emerges as the adrenal vein on the anterior surface of the gland. The right adrenal vein drains into the vena cava inferior and the left one into the renal vein. Adrenal arteries are accompanied by the corresponding veins. The superior adrenal vein drains toward the inferior phrenic vein. The middle adrenal vein drains into the adrenal vein, and the inferior one into the renal vein.

The effect of racemic(?) gossypol and total glycosides of tripterygium wilfordii (GTW) on human sperm acrosome reaction was observed by indirect immunofluorescence and transmission electron microscopy. The results indicate that recemic (?) gossypol and GTW may significantly inhibit human sperm acrosome reaction induced by ionophore A_(23187) at 5mg/L and 10mg/L respectively. The results of TEM shows that racemic (?) gossypol and GTW may injure the sperm plasma membrane.