1.Noise pollution and its public health consequences
Tuguldur M ; Ariunsanaa B ; Enkhjargal A
Mongolian Medical Sciences 2026;217(3):80-87
Introduction:
Noise pollution is an important environmental factor that can adversely affect human health
and quality of life. Exposure to excessive or prolonged noise is associated not only with hearing
impairment but also with sleep disturbance, psychological stress, cognitive dysfunction, and
cardiovascular health risks.
Goal:
The aim of this review was to examine the effects of noise pollution on human health, with
particular attention to the short- and long-term consequences of noise exposure and its
physiological, psychological, cognitive, and cardiovascular effects.
Materials and Methods:
A narrative review of scientific literature was conducted using the references included in the
present study. Published research addressing environmental and transportation noise, noise
exposure, sleep disturbance, stress-related responses, cognitive function, cardiovascular
health, mental health, and related outcomes was reviewed and synthesized. The reviewed
evidence was considered according to exposure duration, intensity, and reported health
effects.
Results:
The reviewed studies indicate that short-term exposure to high-intensity noise may cause
annoyance, fatigue, reduced concentration, sleep disturbance, and temporary physiological
and psychological responses. Prolonged and repeated exposure may increase the risk of
sleep disorders, psychological stress, cardiovascular disease, hearing impairment, and
cognitive dysfunction. Environmental noise may also affect children’s language, reading,
and comprehension abilities. Transportation noise has been associated with cardiovascular
and immune-system responses, while anthropogenic noise can affect communication and
behavior in various animal species.
Conclusion
Noise pollution should be considered a significant environmental health risk extending beyond
hearing damage. Reducing exposure to excessive environmental noise and implementing
appropriate noise-control measures are important for protecting human health, improving
quality of life, and supporting ecological well-being.
2. Result of antimicrobial activity of antibiotic encapsulated in liposomes
Enkhtaivan E ; Enkhmaa O ; Nyam-Ochir E ; Bayasgalan B ; Odonchimeg M ; Lodoidanzan A ; Unursaikhan S ; Enkhjargal D ; Baatarkhuu O ; Ariunsanaa B
Mongolian Medical Sciences 2023;206(4):3-8
Introduction:
The treatment of antibiotic-resistant bacterial infections has become a pressing problem for humanity
worldwide, and antibiotic-resistant bacterial infections are likely to be the leading cause of death
by 2050.Due to the mutation of infectious disease-causing bacteria and the emergence of bacterial
resistance due to the improper use of antibiotics, the time and cost of infectious disease treatment
increases, and in some cases, it leads to an increase in mortality, so it is the focus of the health sector
in every country, regardless of the income level of the population. In addition, bacterial resistance has
a negative impact on public health, food safety, the environment, and the economy.
As of 2015, Mongolia ranks among the countries with the highest consumption of antibiotics in the
world, with 64.41 units of antibiotics prescribed per 1,000 people per day. Bacteria resistant to broad
spectrum antibiotics have increased dramatically, and among Gram-positive bacteria, drug-resistant
Staphylococcus aureus (MRSA) has become one of the most common and dangerous cause
Purpose:
Determine the external structure of liposome-encapsulated antibiotics and evaluate their antibacterial
activity.
Materials and Methods:
We conducted this study using an experimental research design. Phospholipids were isolated by
intermittent evaporation, antibiotic encapsulation by freeze-thaw method, and antibiotic sensitivity was
determined using standard strains by disc diffusion andmicro dilution method.
Research ethics:
Permission to submit the survey was granted by the Ethics Review Committee of the MNUMS. The
survey was granted in accordance with the rules and regulations.
Results:
In liposome-encapsulated antibiotic sensitivity assays, azithromycin and clarithromycin did not form
sacred circles, whereas doxycycline hyclate was sensitive by forming a 16 mm circle. Doxycycline
hyclate encapsulated in liposomes formed a 16 mm circle with sensitive results, whereas blank liposomes were inactive. When the rabbits were infected with a standard strain of methicillin-resistant
Staphylococcus aureus, the infected area was purulent 24 hours later. A cream containing antibiotics
was started at this time. A deep wound was recovered after 12 days after the pus was removed.
Nevertheless, after 24 days, the wound on the rabbit’s infected part healed and the hair on the scraped
part grew back.
Conclusion
According to the dilution method, liposome-encapsulated doxycycline hyclate inhibited bacterial
growth at 2-fold lower doses than pure doxycycline hyclate. In experimental animal models,
liposome-based antibiotic ointment has shown antibacterial activity.
3.Diagnosis and treatment principles on adults with community acquired pneumonia in the out of hospital condition
Ulziisaikhan S ; Ichinnorov D ; Ariunsanaa B ; Choijamts G
Mongolian Medical Sciences 2012;159(1):64-72
Abstract. This article refers to the management of adults with community acquired pneumonia (CAP) of all ages in the community or in hospital. Details of general investigations for patients managed in the community and for patients admitted to hospital, treatment in community, hospitals and in intensive care unit, follow up planning, empirical antibiotic choice, duration of antibiotic administration, failure to improve, the level of evidence of recommendations are given in the text and are summarized in figures and tables. Severity assessment is recommended as the key to planning appropriate management both in the community and in hospital. Certain adverse prognostic features have been associated with an increased risk of death and should be assessed in all patients. Patients who have two or more “core” adverse prognostic features are at high risk of death and should be managed as having severe pneumonia. Patients who display no adverse prognostic features can be managed as having non-severe pneumonia and may be suitable for outpatient treatment or early hospital discharge.
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