Introduction: This study aimed to assess psychological distress among nursing students enrolled in bachelor’s and associate degree programs using the DASS-21 (Depression Anxiety Stress Scales-21). Objective: To evaluate levels of depression, anxiety, and stress and analyze their differences by age, gender, and year of study. Methods:: A cross-sectional design was employed. Data were collected from students and analyzed by age, gender, and year of study. Depression, anxiety, and stress levels were measured using DASS-21 standard scoring and categorized accordingly.
The findings showed that psychological distress levels were generally consistent with international trends. Bachelor’s students demonstrated higher levels of depression and stress, particularly in the second and final years. Anxiety levels were moderate among first- to third-year bachelor’s students. In contrast, associate degree students mostly exhibited normal to mild levels across all three domains. Female students reported relatively higher levels of depression and anxiety. Academic workload, clinical practice demands, financial difficulties, and environmental stressors such as traffic congestion and air pollution were identified as contributing factors. Conclusion Psychological distress among nursing students varies by academic level and is influenced by multiple factors. The results highlight the importance of implementing targeted mental health support and preventive interventions tailored to students’ academic stages.

Introduction: Psoriasis vulgaris is a chronic, immune-mediated inflammatory dermatosis characterized by erythematous, scaly plaques that substantially impair physical, psychological, and social well-being. Although modern therapies—topicals, phototherapy, systemic agents, and biologics—have improved disease control, many patients experience incomplete remission, adverse effects, or limited accessibility. Traditional Mongolian soaking therapy, particularly the “Five medicinal Springs” decoction, has historically been used to alleviate psoriasis-like conditions; however, contemporary evidence generated through rigorous clinical study remains limited. This randomized controlled trial aimed to evaluate its efficacy and safety. Methods: A total of 60 adults with psoriasis vulgaris were enrolled between October 2019 and February 2022 at the Affiliated Hospital of Inner Mongolia University for Nationalities. Participants were randomized equally into an intervention group (n=30) and a placebo group (n=30). The intervention group received daily decoction baths prepared from ledum palustre. L, Juniferus dahurica Pall, Myricaria longifolia Willd. Ehrenb, Ephedra monosperma S.G.Gmel ex C.A.Mey, and Artemisia frigida Willd, combined with composite glycyrrhizic acid and a hyaluronic biological membrane. The placebo group received warm-water baths with identical adjunct therapy. Treatment spanned 4 consecutive weeks. Clinical outcomes included PASI and its sub scores (erythema, scaling, infiltration), lesion area, pruritus score, Dermatology Life Quality Index (DLQI), and dermatoscopic grading. Statistical analysis employed Mann–Whitney U, Wilcoxon signed-rank, and χ² tests, with significance set at p<0.05.
Baseline characteristics were comparable between groups. After 4 weeks, the intervention group demonstrated significantly greater improvement in erythema (3.23→1.50), scaling (2.90→1.37), and infiltration (2.57→0.77) (all p<0.001). Overall clinical efficacy was higher in the intervention arm (76% vs 53%; p=0.031). DLQI, pruritus scores, and dermatoscopic findings also improved more prominently in the intervention group. No serious adverse events or abnormal laboratory findings were observed. Conclusion Four weeks of “Five medicinal Springs” decoction bathing produced meaningful clinical improvement in psoriasis severity, symptoms, and quality of life, with an excellent safety profile. Further multicenter, long-term randomized trials are warranted to validate these findings and elucidate underlying mechanisms.

Abstract According to the World Health Organization (WHO) report in 2023, arterial hypertension (HTN) remains one of the leading causes of global morbidity, with an estimated 1.3 billion individuals diagnosed worldwide. Among them, 42% were receiving antihypertensive treatment, and only 21% achieved adequate blood pressure control. In the United States, 47.7% of the adult population is diagnosed with hypertension, with prevalence increasing significantly with age [1,2]. Multiple factors such as lifestyle, body mass index (BMI), age, sex, genetics, and physical inactivity are well-documented contributors to hypertension, as evidenced by both international and local studies. Specifically, individuals classified as obese demonstrate a higher prevalence of hypertension based on BMI categorization.
However, in Mongolia, limited studies have investigated the contributing factors and treatment outcomes of hypertension, highlighting the necessity of this study.
A retrospective study was conducted by reviewing the medical records of 50 inpatients diagnosed with arterial hypertension (ICD-10 codes I10–I15) who were admitted to Sindura-Med Hospital between 2023 and 2024.
1. In patients with stage 1 and 2 arterial hypertensions, age, mean systolic and diastolic blood plessure, heart rate and elevated cholesterol levels were found to be correlated with body mass index (BMI). Among smokers, the risk of developing cardiovascular diseases is projected to increase over the next 10 years
2. In the hypertensive group aged 60 years and older, echocardiographic examination revealed structural and functional abnormalities.
3. In the pharmacological management of arterial hypertension, calcium channel blockers, angiotensin converting enzyme (ACE) inhibitors, combination preparations, and diuretics were the most commonly prescribed medications.

Abstract The Five Medicinal Essences (“Ganlu”) are traditionally described in Mongolian medicine as five sacred, sweet elixirs believed to promote health and longevity. This concept is incorporated into the theoretical framework of traditional fomentation therapy, which aims to restore balance among physiological functions, mental state, and internal energy.
The formulation consists of five plant materials: Ledum palustre L., Juniperus dahurica Pall., Myricaria longifolia (Willd.) Ehrenb., Ephedra przewalskii Stapf, and Artemisia frigida Willd., combined in a ratio of 1:1:2:2:3. The herbal materials are prepared as a decoction and administered as a medicinal extract for external therapeutic application in balneotherapy.
Traditionally, this formulation has been used in Mongolian and integrative medical practice for the management of rheumatic joint disorders, ankylosis, spondylitis, brucellosis, postpartum wind-related disorders, dermatological diseases—particularly psoriasis—and neurological conditions such as hemiplegia and paralysis. Reported therapeutic effects include improvement of blood circulation, modulation of physiological functions, stimulation of metabolic processes, promotion of detoxification, muscle relaxation, and relief of localized pain. However, the therapy is contraindicated in patients with acute infectious diseases (e.g., typhoid fever), severe systemic debilitation, purulent or inflammatory conditions, necrotizing processes, stage II–III hypertension, malignant neoplasms, or venous thrombosis.
Further pharmacological and clinical investigations are necessary to clarify the mechanisms of action of the constituent plants and to provide scientific evidence supporting the integration of this traditional formulation into modern healthcare practice.

Abstract Temperament is an innate psychological characteristic that influences emotional responses, behavioral patterns, learning styles, and academic performance. In educational settings, understanding students’ temperament has become increasingly important for improving learning outcomes, engagement, and instructional effectiveness.
This review aims to synthesize theoretical and empirical evidence on the relationship between student temperament and learning outcomes, and to identify teaching methods and instructional strategies that are aligned with different temperament types.
In reviewed studies, a variety of methods have commonly been used to assess students’ learning styles, temperament, and psychological attitudes, including questionnaires, learning ability tests, standardized psychological tests, and teacher evaluations. Statistical techniques such as correlation, regression, and cluster analysis are often employed to analyze data and provide a comprehensive evaluation of learning outcomes.
Previous studies consistently demonstrate that temperament significantly influences learning behavior, attention, stress responses, and academic achievement. Sanguine and choleric students benefit more from interactive and competitive learning environments, whereas phlegmatic and melancholic students achieve better outcomes in stable, structured, and supportive settings. Empirical evidence further suggests that aligning teaching strategies with students’ temperament characteristics enhances learning effectiveness and student engagement.
Temperament is a critical individual factor affecting learning outcomes and academic success. Rather than attempting to change temperament, educational strategies should focus on recognizing and supporting individual differences.
Integrating temperament-sensitive teaching approaches into curriculum design can substantially improve educational quality and learning outcomes.

Introduction: Clinical practice is a critical component of professional development for healthcare students; however, exposure to ethical dilemmas is common in real clinical settings. Limited evidence exists regarding how nursing and traditional medicine students make ethical decisions during clinical practice and the factors influencing their decision-making in the Mongolian context. Methods: A mixed-methods design was employed. The quantitative phase included 95 undergraduate students undertaking clinical practice. Ethical decision-making was assessed using a 16-item Likert-scale questionnaire based on Rest’s Four-Component Model of Moral Behavior. The qualitative phase involved semi-structured phenomenological interviews with 18 purposively selected students. Quantitative data were analyzed using SPSS version 28.0 and R software, while qualitative data were interpreted using Van Manen’s hermeneutic phenomenological approach. Results: The mean ethical decision-making score was 65.06 ± 9.96, with 66.3% of participants demonstrating a high level of ethical competence. Ethical sensitivity showed the lowest mean score (15.87 ± 3.02) among the four components. Significant positive correlations were identified among ethical sensitivity, moral judgment, moral motivation, and moral character (r = 0.592–0.747, p < .001). Qualitative analysis revealed five major themes influencing ethical decision-making: ethical awareness, fear and lack of moral courage, hierarchical relationships and organizational culture, support systems, and personal moral development. Students frequently reported difficulties in acting on ethical concerns due to perceived authority gradients and evaluation-related pressures. Conclusion Although students demonstrated a generally high level of ethical decision-making competence, deficiencies in ethical sensitivity and institutional support were evident. Strengthening ethics education through case-based learning, simulation training, reflective discussions, and supportive clinical learning environments may enhance students’ ethical decision-making capabilities.

Introduction Betulin, a pentacyclic triterpenoid abundant in the outer bark of birch trees (Betula pendula Roth.), has gained significant attention in pharmaceutical research due to its potent anti-inflammatory, antioxidant, and skin-regenerative properties. However, its therapeutic application is severely hindered by its extreme lipophilicity and poor aqueous solubility, leading to low bioavailability. Conventional topical formulations often fail to deliver betulin across the skin’s lipid barrier, retaining it primarily in the stratum corneum. Furthermore, while betulin exhibits efficacy against Gram-positive bacteria (S. aureus, B. subtilis), recent studies indicate a lack of inhibitory effect on Gram-negative strains (E. coli), presenting a challenge in the comprehensive management of infected burn wounds.
To address these limitations, this study proposes a "dual-action" hybrid delivery system by integrating betulin with metallic nanoparticles (AgNPs and ZnO NPs) using nanotechnology-based platforms. These nano-structured systems—such as liposomes and nano-emulsions are designed to enhance the solubility of betulin, facilitate deep dermal penetration, and reduce systemic side effects. Simultaneously, the inclusion of silver and zinc oxide nanoparticles expands the antimicrobial spectrum to include Gram-negative pathogens and provides antiseptic synergy.
This innovative approach provides a robust scientific and technological framework for developing next-generation dermatological products. By utilizing Mongolia's extensive birch forest resources, this research contributes to the production of high-value, export-oriented pharmaceutical innovations that serve as advanced alternatives to imported wound-care treatments.

Introduction: Antibiotics are commonly prescribed in paediatrics.¹ Children were 1.3 times more likely to be treated with antibiotics compared to adults.² Especially, antibiotic prescription is higher in children aged under 5 years.³ Purpose: To identify the most widely used antibiotics in the age group of 0-5. Objectives of the study:
1. To identify the most widely used antibiotics and classify them by pharmacological group
2. To analyze the pharmaceutical dosage forms of commonly prescribed antibiotics for infants and toddlers Methods: In our study, we selected 20 pharmacies from 6 districts (Bayanzurkh, Bayangol, Khan-Uul, Songinokhairkhan, Chingeltei, and Sukhbaatar) of Ulaanbaatar city using a single random sampling method. A total of 496 antibiotic prescriptions written for children aged 0-5 years in 20 pharmacies were analyzed. Antibiotic prescription forms for children aged 0-5 years registered in the pharmacies in November, December 2023, and January 2024 were collected. The results were processed using “SPSS 29.0.2” program. Result: Among a total of 496 antibiotic prescriptions written for children, 341 were written in solid dosage form and 155 were in liquid dosage form (suspension). Amoxicillin 250 mg and Amoxiclav 312.5 mg were mostly used from Penicillin group for the treatment of infants and toddlers. Clarithromycin 125mg/5ml from Macrolide group had an important role in treatment. Cefixime 400 mg from the Cephalosporin group was used in some cases such as diarrhea and vomit. Conclusions
1. Amoxicillin, Amoxiclav, Clarithromycin (Penicillin, Macrolide) antibiotics are the most widely used in the treatment of infants and toddlers.
2. It has concluded that antibiotic prescriptions for infants and toddlers mainly include solid and suspension antibiotics.

Introduction: Among the ancient medical books, manuscripts written in clear script, with unique vocabulary and treatment methods, have been found. The vocabulary in this work is very ancient, and the treatment methods are systematic, with few mentions of theoretical concepts. Most of the unfamiliar words were written in the pronunciation of the ancient Oirat Torghut and Dorbet. Some of these words were of Uyghur and Sartuul (Khui Khui) origin. Therefore, we worked to determine when and by whom this book was written, what its content was, and which direction of medicine it belongs to. Objectives: To study an ancient book written in clear script, containing Islamic medical knowledge, found in Mongolia. Results “The Healing Charm of Blue Ram” (Khökh khutsyn uvdis orshivai) records that Genghis Khan ordered Chagatai Khan to send him medical books from his land. He may have been in poor health shortly after the founding of the Chagatai state in 1225. Thus, he ordered Chagatai to send him books containing medical methods. It is reasonable to assume that the books were sent in 1226. At that time, the Chagatai state was highly developed, consisting of many ethnic groups, including Khorezm, Sartuul, and Uyghurs, who practiced Islam. In particular, the medical field was well advanced, resulting in many excellent doctors and medical books. We tried to list and explain a total of 15 words from “The Healing Charm of Blue Ram,” with many more to explore in the future. In general, it is hypothesized that many vocabulary related to medicine have spread to the Mongolian vocabulary through Arabic, Turkic, Uyghur, and Sartuul among the Western Mongolians. Conclusion: The ancient book “The Healing Charm of Blue Ram” found in Mongolia, written in clear Mongolian script, contains Islamic medical knowledge, as well as traditional Mongolian medicine methods, as is clear from the explanations of some vocabulary related to medicine. In the future, it is important to further clarify how Mongolian medicine and Islamic medical knowledge influenced each other and the contribution of Mongol khans to the development of the Ilkhanate and the Chagatai state in the study of the history of Mongolian medicine.

Background: Organ transplantation has been rapidly advancing in Mongolia in recent years. The number of successful kidney, liver, and bone marrow transplants performed in national central hospitals has been increasing annually. While the number of successful kidney transplants is increasing, post-transplant immune monitoring remains insufficiently studied. Aim: To assess post-transplant immune status by analyzing inflammatory cytokine levels in kidney transplant recipients Materials and Methods: A prospective cohort study was conducted at the First Central Hospital of Mongolia. Serum samples from kidney transplant recipients were analyzed using flow cytometry to measure the levels of 13 inflammatory cytokines, including TGF-β1, PAI-1, sTREM-1, PTX3, sCD40L, sCD25 (IL-2Ra), CXCL12 (SDF-1), sST2, sTNF-RI, sTNF-RII, sRAGE, CX3CL1 (Fractalkine), and sCD130 (gp130). Statistical analysis was performed to assess the results. Results: The mean creatinine level significantly decreased on post-transplant days 7 and 30 compared to pre-transplant levels (p<0.001, ANOVA). No statistically significant difference was found in the 13 cytokine levels between the high risk and low-risk groups based on creatinine levels on post-transplant day 30 (p>0.05). However, the levels of TGF-β1, CX3CL1, sTREM-1, and sTNF-RI showed statistically significant differences between post-transplant days 7 and 30 (p<0.05). No significant correlation was found between the measured cytokine levels and CRP (p > 0.05). On post-transplant day 7, sTREM-1 had a weak correlation with TGF-β1 (r=0.40, p=0.02) and sTNF-RI (r=0.36, p=0.05) but showed a strong correlation with CX3CL1 (r=0.65, p=0.0001). On post-transplant day 30, sTREM-1 remained strongly correlated with CX3CL1 (r=0.73, p=0.0001) and moderately correlated with sTNF-RI and TGF-β1 (r=0.45, p=0.01). Conclusions 1. The levels of TGF-β1, CX3CL1, sTREM-1, and sTNF-RI significantly varied between post-transplant days 7 and 30 (p< 0.05, T-test). 2. On post-transplant day 30, these cytokines were not correlated with CRP but were interrelated among themselves.