1.Characterization of gastroesophageal reflux disease phenotypes using 24-hour multichannel intraluminal impedance–pH monitoring study
Ankhbayar D ; Amarjargal B ; Bira N ; ; Sarantuya G ; ;
Mongolian Journal of Health Sciences 2026;95(5):212-216
Background:
In contemporary clinical practice, gastroesophageal reflux disease (GERD) is classified into four phenotypes based on upper gastrointestinal endoscopy and 24-hour multichannel intraluminal impedance-pH monitoring: erosive reflux disease (ERD), non-erosive reflux disease (NERD), reflux hypersensitivity (RH), and functional heartburn (FH). Although the prevalence of GERD in Mongolia is high, and certain chronophysiological aspects have been investigated, there remains a significant lack of data regarding GERD phenotypic classification and physiological diagnostic evaluation using impedance-pH monitoring. This knowledge gap provided the rationale for conducting the present study.
Aim:
To determine the prevalence of GERD phenotypes among adults presenting with heartburn symptoms and to compare selected manometric and pH-impedance parameters among phenotype groups.
Materials and Methods:
This study analyzed data from 347 adults who presented to Intermed Hospital between 2022 and 2025 with heartburn symptoms and underwent 24-hour multichannel intraluminal impedance-pH monitoring. Statistical analysis was performed using SPSS version 26.
Results:
Among the study population, 193 patients (55.6%) were diagnosed with ERD, 34 (9.8%) with NERD, 73 (21.0%) with RH, and 47 (13.5%) with FH. Significant differences were observed among the groups in body mass index (BMI), esophageal acid exposure, total reflux episodes, reflux characteristics, and mean nocturnal baseline impedance (MNBI). Type III esophagogastric junction morphology was identified in 78.76% of the ERD group, 64.7% of the NERD group, 56.2% of the RH group, and 42.6% of the FH group, demonstrating statistically significant intergroup differences.
Conclusion
ERD was the predominant GERD phenotype among adults with heartburn symptoms, followed by RH, FH, and NERD. Significant differences among GERD phenotypes were observed in BMI, total reflux burden, reflux characteristics, esophageal nocturnal baseline impedance, and esophagogastric junction morphology.
2.A clinical case of anterior open bite with skeletal class III malocclusion treated with combined orthodontic and orthognathic surgery using TADs
Uyanga O ; Oyunjargal M ; Tsasan T ; Ankhbayar G ; Gannaran N ; Od B
Mongolian Journal of Health Sciences 2026;95(5):336-339
Background:
Anterior open bite involving the anterior dentition associated with skeletal Class III malocclusion is a severe dentofacial deformity resulting from discrepancies in vertical and sagittal relationships of the maxilla and mandible. In adult patients, orthodontic treatment alone is insufficient to achieve satisfactory outcomes; therefore, combined orthodontic and orthognathic surgical treatment is required.
Case Presentation:
A 21-year-9-month-old female patient presented with a chief complaint of mandibular prognathism. Clinical and radiographic examinations revealed anterior open bite involving the anterior dentition associated with skeletal Class III malocclusion. The treatment was carried out in three phases. Presurgical orthodontic treatment was performed to achieve dental decompensation, followed by orthognathic surgery. Le Fort I osteotomy was performed to reduce the vertical height by 3 mm and advance the maxilla by 5 mm, while bilateral sagittal split osteotomy (BSSO) was performed to set back the mandible by 9 mm. Post-surgical orthodontic treatment was performed using temporary anchorage devices (TADs) to provide stable anchorage, allowing precise control of tooth movement, and intermaxillary elastics were used to refine occlusion. As a result, facial profile, skeletal relationships, and occlusion were improved, with stable outcomes achieved.
Diagnosis:
Extraoral examination revealed a mandibular facial profile, increased height of the lower third of the face, normal facial midline at the nose, and a 1.5 mm leftward deviation at the chin. Lip position was -6 mm for the upper lip and -2 mm for the lower lip relative to the nasolabial angle. The angle between the cheekbones and the lips was 55.5°.
Conclusion
Combined orthodontic and orthognathic surgical treatment provides effective and stable outcomes in terms of esthetics, function, and occlusal stability in adult patients with anterior open bite associated with skeletal Class III malocclusion.
3.Management and monitoring of hypokalemia occurring during certain diseases
Temuulen Ts ; Maral B ; Baasanjargal B ; Agidulam Z ; Burenbayar Ch ; Ankhbayar D ; Tsogdulam S ; Amardulguun S ; Otgon-Erdene M ; Anujin G ; Khongorzul U1 ; Delgermaa Sh ; Odgerel Ts
Mongolian Journal of Health Sciences 2025;86(2):51-54
Background:
Hypokalemia is considered when the serum potassium level is less than 3.5 mmol/L. Clinical research indicates
that hypokalemia affects 20% of hospitalized patients, and in 24% of these cases, inadequate interventions result
in life-threatening complications. At present, there is no research available on the prevalence, management, and outcomes
of hypokalemia in hospitalized patients, which justifies the need for this study.
Aim:
The study aimed to examine the prevalence of hypokalemia and the effectiveness of its management in hospitalized
patients within the internal medicine department, in relation to the knowledge of doctors and resident physicians.
Materials and Methods:
This hospital-based retrospective study included a total of 553 cases of patients hospitalized in
the Internal Medicine Department of the Mongolia Japan Hospital between January 2024 and August 2024. Patients with
a potassium level of <3.5 mmol/L were diagnosed with hypokalemia, and the effectiveness of potassium replacement
therapy was evaluated according to the method of supplementation employed.
Results:
The prevalence of hypokalemia among hospitalized patients in the Internal Medicine Department was 9.8%
(54 cases). Based on the study criteria, 42 cases of hypokalemia were selected for further analysis, and a total of 118 potassium
replacements were performed through oral, intravenous, and mixed methods. Following potassium replacement
therapy, 37.3% (44) of patients achieved normalized potassium levels, while 62.7% (74) still had persistent hypokalemia.
Conclusion
According to the study results, the prevalence of hypokalemia among hospitalized patients in the Internal
Medicine Department is 9.8%. The method of potassium replacement and the severity of hypokalemia do not impact the
normalization of potassium levels, with the critical factor being the proper dosage of supplementation. The knowledge
of doctors and resident physicians regarding hypokalemia is insufficient, and there is a need to implement guidelines and
protocols for potassium replacement therapy in daily clinical practice.
4. THE TREATMENT OUTCOME OF HEPATOCELLULAR CANCER
Gan-Erdene B ; Chinburen J ; Narmandakh TS ; Altanchimeg N ; Onon B ; Sanchin U ; Bilguun G ; Ankhbayar E ; Tuvshinbayar M
Journal of Surgery 2016;19(1):37-40
Introduction: Hepatocellular carcinoma(HCC) is the 6th most common cancer inthe world, but the first most commoncause of cancer death in Mongolia. Thereis no universally accepted consensuspractice guidelines for HCC owing to rapiddevelopments in new treatment modalities,the heterogeneous epidemiology and clinicalpresentation of HCC worldwide.Methods and Materials: This study wasconducted in the department of generalsurgery of Second Central Hospital ofMongolia between 2015 and 2016 on a totalof 36 patients with hepatocellular carcinoma.Results: The average of operationtime is a 132.2 min, the hospital stay 18.2days. Postoperative bleeding was 2.7% (1),encephalopathy 5.4% (2), wound infection5.4% (2), and incisional hernia 8.1% (3).There were not bile leak during 30 dayspostoperative day.Conclusion: Postoperative complicationis a comparable to different researcher.There were no death within first month.
Result Analysis
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