1.Acute Abdomen: Unmasked the Bleeding Site in Severe Haemophilia A
Wan Suriana Wan Ab Rahman ; Zefarina Zulkafli ; Mohd Nazri Hassan ; Wan Zaidah Abdullah ; Azlan Husin ; Anani Aila Mat Zain
Malaysian Journal of Medicine and Health Sciences 2020;16(No.2):345-347
Haemophilia A is an inherited bleeding disorder, commonly involve soft tissues and joints. Gastrointestinal tract bleeding, are not uncommon but seldom highlighted. A 23-year-old male with underlying severe haemophilia A was presented with a generalised abdominal pain for 2 days, abdominal distension, diarrhoea and vomiting. He did not have any trauma to the abdomen. Abdominal examination revealed generalized tenderness with sign of guarding on palpation. Laboratory investigations revealed isolated, prolonged activated partial thromboplastin time (APTT) with normal total white blood cell count and haemoglobin level. In view of acute abdomen, which was not resolved by conservative treatment, an emergency laparotomy was done with FVIII concentrate and recombinant factor VII (rFVII) coverage. Intraoperative findings noted patchy gangrenous spots of about 30 cm in length in the small bowel. Histopathology examination revealed an evidence of haemorrhage within the submucosal and intramuscularis layer from the resected specimen. This case highlighted the possibility of gastrointestinal bleeding without prior trauma, which can be presented as acute abdomen in severe haemophilia patient.
2.Mucoepidermoid carcinoma of the thyroid gland
Anusha BALASUBRAMANIAN ; Irfan MOHAMAD ; Nur Asyilla CHE JALIL ; Anani Aila MAT ZAIN ; Wan Faiziah WAN ABDUL RAHMAN
Brunei International Medical Journal 2013;9(3):191-194
Mucoepidermoid carcinoma (MEC) of the thyroid gland either primary or metastatic is extremely rare. However, MEC is the most common malignant tumour of the salivary glands with the majority originating from the parotid gland. We report the case of a 54-year-old Malay lady who presented with recurrent MEC affecting the thyroid gland two years after being treated for primary parotid MEC.

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