Background: Plants of the genus Achillea are widely used in both traditional and modern medicine and are known to be rich in biologically active secondary metabolites. Numerous phytochemical and histochemical studies have been con ducted on Achillea millefolium L.; however, Achillea asiatica Serg., which is widely distributed in Mongolia, remains comparatively underexplored. Therefore, investigating the distribution of biologically active compounds, the content of polyphenolic compounds, and the optimal extraction conditions of this species is of significant scientific and practical importance. Aim: The aim of this study was to identify biologically active compounds in Achillea asiatica Serg. using histochemical methods, to determine the content of polyphenolic compounds and optimal extraction conditions, and to evaluate the total and internal absorption coefficients of the plant raw material. Materials and Methods: The aerial parts of Achillea asiatica Serg. were collected in August 2025 from Erdene soum, Tuv province, Mongolia. Histochemical analysis was performed on transverse stem sections and flower petals using potassium dichromate, ferric chloride (III), methylene blue, Lugol’s iodine, and Dragendorff’s reagent, followed by ob servation under a light microscope. The total polyphenolic content was determined using the Folin–Ciocalteu method and expressed as gallic acid equivalents. Extraction experiments were conducted using powdered plant material sieved to par ticle sizes of 1, 2, and 3 mm and extracted with 20–80% ethanol. In addition, the total and internal absorption coefficients of the plant material were determined according to standard procedures. Results: Histochemical analysis revealed the presence of essential oils, polyphenolic compounds (tannins and flavo noids), and starch, while alkaloids were not detected. Polyphenolic compounds were observed in both stems and flow ers, with more pronounced accumulation in the vascular tissues. The highest total polyphenolic content (0.421%) was obtained from the 1 mm particle-size fraction extracted with 70–80% ethanol. Using 60% ethanol, the total absorption coefficient of the plant material was determined to be 5.74, and the internal absorption coefficient was 1.885. Conclution Achillea asiatica Serg. is rich in polyphenolic compounds, and their anatomical distribution is closely as sociated with the plant’s protective and biological functions. The use of 1 mm particle-size material and 70–80% ethanol was identified as the most suitable condition for extracting polyphenolic compounds. These findings provide a scientific basis for the standardization of Achillea asiatica Serg. as a medicinal and phytopharmaceutical raw material and support its further pharmacognostic and phytochemical investigation.

Background: The development of a country is often measured by the state of human development, especially maternal and child health indicators. In Mongolia, public health policies targeting the prevention of non-communicable diseases related to lifestyle and physical development among adolescents are critically needed. However, there is a lack of regional studies on adolescent health, particularly in rural areas. Aim: To study certain physical development indicators among adolescents in Bulgan province. Materials and Methods: This analytical study was conducted in 2022 involving 781 twelve-year-old children. Data were collected from parents and processed using Stata 17.0. Percentages were calculated for qualitative data, and Chi-square and Fisher’s exact tests were used for statistical analysis. Where statistically significant, multinomial logistic regression analysis was applied to identify risk factors affecting physical development. Results: 52.88% of the participants were boys,92.45% lived in traditional or private hous12.04% of the children showed growth retardation. 49.68% were overweight.70.94% were classified as overweight or obese based on their Body Mass Index (BMI).Weak muscle strength (1.66%), flexibility (2.05%), endurance (1.66%), and agility (1.92%) were observed. Boys were more likely to experience height retardation but had stronger muscle strength.Girls showed a higher prevalence of being overweight.Children living in the provincial center had higher height and BMI, while those in soum centers demonstrated statistically significant strength in muscle power, flexibility, and endurance. Conclusion 1. Among the study participants, 70.94% of children were overweight or obese. 2. 1.66% of the study participants had weak muscle strength, 2.05% had weak flexibility, 1.66% had weak endurance, and 1.92% had weak speed and agility. 3. The use of mobile phones, parental involvement, inactivity, lack of sports, and lack of horse riding have negative effects on physical development.

Background: Individuals requiring liver transplantation began receiving this procedure in Mongolia in 2011, following initial treatments abroad in 2004. As survival rates of post-liver transplant continue to improve, it is imperative to understand the factors influencing the quality of life for patients during these years and to explore modifiable determinants. The interplay between socioeconomic and environmental factors significantly impacts social and personal development, as evidenced by quality of life metrics. Research indicates that 6% of liver transplant recipients are classified as unable to work based on activity and international disability assessments, while 23% to 61% of recipients achieve full employment following liver transplantation treatment. However, there is a notable lack of studies examining the physical, psychological, and social well-being of patients post-liver transplant in Mongolia. This study aims to address this gap and provide insights into the overall health status of these individuals. Aim: Examining quality of life and employment status following liver transplantation treatment Materials and Methods: A descriptive study design and questionnaire method were used to collect data from 144 cases of individuals who underwent liver transplantation. The study was based on the SF-36 Health Survey, categorized into eight domains, with scores calculated according to predefined criteria. Results: Among the 144 cases included in the study, 81 (56.3%) were male and 63 (43.8%) were female. By age group, 120 (83.3%) were between 19 and 60 years old, representing the working-age population, while 24 (16.7%) were over 60 years old. Post-liver transplant employment status revealed significant differences, with 41 (28.5%) employed full-time, 19 (13.2%) parttime, and 84 (58.3%) unemployed or receiving disability benefits (p=0.024). Among these, 62 (43%) expressed a desire to work, 17 (12%) did not wish to work, and 65 (45%) were uncertain, showing no statistically significant differences (p=0.173). When calculating the quality of life assessment, the physical function index was 63.52±25.32 for working patients and 52.90±25.75 for non-working patients (p=0.018), and the psychological status index was 64.94±14.53 for working patients and 53.63±17.87 for non-working patients (p<0.001), and there was a statistically significant difference. Conclusion Health-related quality of life in people who are employed after liver transplantation is high, and overall physical function and overall psychological well-being improve year after year.

Background: A particular appealing problem in the medical field of our country is non-communicable diseases, which are derived from child development and lifestyle, prevention and the decision was approved on being used the maternal and child health handbook in order to be promptly needed the publicly covered medical policy toward those. Several researchers have noted that in developed countries longitudinal studies are used for checking and controlling in wide range of epidemic diseases and health issues for maternal and child, pregnancy and postpartum period as well as this method is directed to be found out multiple information and knowledge. Not having studied enough how well current situations for postpartum period and maternal and child health in our countryside is become the foundation for our research work. Moreover, it needs to be found out what kind of factors, which are effected on children who were born to the year of 2010 in Bulgan province, where it started using the first and only maternal and child health handbook (so called a pink handbook) in Mongolia, health issues. Also, the foundation of this study was to be needed to focus on our attention to which level of the medical field in order to improve those generations health issues are improved, Aim: to evaluate of a written usage of the maternal and child health handbook, to define its needs, to advertise its results to the public. Materials and Methods: The study is made with a cohort design of an analytical method based on collected information in 2013, of mothers and children, who are in need, giving birth and being born in 2010 and the results were made on Stata 17 program. The answers were taken with the base study of 2013 from 1015 original case sources within study groups in needs, and collected information covered with current and actual local situation, as well as to be involved in mothers and children, who gave birth and were born in 17 sums’ health institutions of Bulgan province. Results: Participants age range and educational backgrounds; 70.34 % of mothers were between 20-34 ages, 29.36% of mothers were 35 and over ages. 1.51% of uneducated mothers, 39.06 % of high school graduates, 49.1% of permanent residents, 45.38 % of temporary or nomadic or the smallest units residents of administration, 92.08% of married, 39.88% of families are consisted in members over 5, 52.12% of boys with average weights of 3389.8 grams during the period of being born, 9.86% of heavy pregnancy or heavy weight fetuses, 4.14% of light weight fetuses or light weight infants. Plus, the study was defined the mothers educational background to be great and helpful strength to use and record and to define the usages of the maternal and child health handbook, which was given and thoroughly explained to the mothers at the beginning. The leading diseases and their reasons were among three-year aged children, who were covered and recorded with 173 severe burnt, 42 falling injuries from something, 22 being hit and 19 were bitten by animals. In this study there were 17.83% of participants without the maternal and child health handbooks (pink handbooks), 81.77% of participants carried their pink handbooks with them when they went to the health facilities, 68.47% of them, who were gotten explanations from the doctors, when the pink handbooks were opened by, 71.72% of participants answered the pink handbooks to be needed. The results of this study have indicated that 71.72% of mothers, who used it at first time, answered the maternal and child health handbooks were very important and handy for understanding to check and observe for mothers and children’s development and growth. Conclusion It was the leading reason, which was predominantly recorded with cases of burning, falling injuries, hit and bitten by animals among three-year of children, who were participated in this study. There were high amounts of respiratory diseases and diarrheas among toddlers. 71.72% of participants considered that the maternal and child health handbooks were important.

The clinical sign of children’s kidney and urinary tract petrification diseases and the result of eswl Background: A substance exchange disorder where stones form in the kidney or urinary tract with a tendency toward inheritance is called urinary tract petrification disease. In many countries throughout the world, the incidence of urinary tract petrification disease is one to fifteen percent. Urinary tract permeability disease affects 7% of people under the age of 17. Due to the unique nature of the habitat, the incidence of urinary tract petrification disease is higher in India, Thailand, Scandinavian countries, and the Caucasian, Ural, Siberia, and Equator areas. However, the incidence of urinary tract petrification disease spread is two to three percent for children, but the reoccurance risk is 6.5–54 percent. In our country’s case, J. Horloo’s 1993 research indicates that 4.1 to 4.7 percent of kidney and urinary tract patients have urinary tract disease. During urinary tract disease, the common symptoms are abdominal pain, macro- and microhematuria, and kidney and renal bacterial infection. But in younger children, those symptoms are quite grim. In the last 15 years, mongolian’s urine’s oxalate stone’s volume increased by 5 times and mixed stones decreased by 2.5 times. The research of G. Erdenetsetseg’s 1990–1998 study on 305 children and the 2001–2003 study on 161 children indicate that the incidence of urinary tract disease is high between ages 1-3, and 65 percent of the stones consist of calcium oxalate. In 1980, German scientists invented the stone crushing technology using electrohydraulic shockwaves, which turned out to be a beneficial treatment for kidney surgery practice. The National Hospital for Maternal and Child Health's kidney surgery team had 17 surgeries in 2015, 19 surgeries in 2016, 24 surgeries in 2017, and 28 surgeries in 2018, and all of those surgeries were done and treated open. In the last 10 years of our country, children’s urinary tract petrification disease has gradually increased, but research on those diseases risks and factors is lacking. Also, the stone crushing method is necessary for our country’s children's treatment. That’s why we decided to do research on the risk factors of urinary tract disease and its relation to the stone crushing method. Aim: Describe the features of children’s kidney and urinary tract petrification disease and study the stone crushing method’s results. Materials and methods: The study was done between December of 2019 and April of 2022, with the assistance of NCMCH's children's kidney surgery team. Within the parameter of the first objective, within the group of cases of kidney and urinary tract disease, there were 13 children under the age of 17. The research study was conducted cross sectional. The research results were processed by the SPSS 25 program. On the seventh meeting of the health ministry, we got the acceptance of a research patent with the assistance of EHEMUT. Results: The research group consisted of 13 children ages 0–17. The average age of participants was 10.6+-4.2.74. 4 percent of it consisted of men. The research of symptoms showed that back pain n = 13 (100), right side abdominal pain n = 13 (100), disurie n = 3 (23.1), mouth drying n = 2 (15.4), nausea n = 3 (23.1), urine with blood n = 10 (76.9), urine with smell n = 9 (69.2). The position of the stone consisted of 8 (61.5) in the kidney cup, 8 in the kidney cradle. Showing it in which kidney showed that 8 (61.5) were in the right kidney, 3 (23.1) in the left kidney, and 2 (15.4) in both kidneys. The density of the stones was n = 265.8+ 41.9 on average. Kidney stone coming out time was measured by Caplan-Myer’s survivability scale. The stones on the right side of the kidney came out within 14 days on average, while the left and both-sided kidney stones came out within 30 days. Conclusions: 1. Showing the number of stones and locations indicates that 8 (61.5) were in the right kidney, 3 (23.1) in the left kidney, and 2 (15.4) in both kidneys. 2. The results of Caplan-Meyer's scale indicate that kidney stones within the right kidney came out within 14 days, and left- or both-sided stones came out within 30 days.

Background: To determine the visual and anatomical outcomes after rhegmatogenous retinal detachment surgery. Methods: Case files of patients who had surgery for rhegmatogenous retinal detachment at the 3rd state central hospital May 2019 and May 2021 were reviewed. Information obtained included age, sex, presenting and post-operative visual acuity, anatomical reattachment, post- operative complications and causes of treatment failure. Results: Risk factors for retinal detachment included myopia in 8 eyes (32%), trauma in 7 eyes (28%), prior cataract surgery in 2 eyes (8%). 22 eyes (88%) presented with macula off while 3 eyes (12%) presented with macula partly or completely attached. Visual acuity at presentation was <0.01 in 15 eyes (60%). Following surgery, retina was attached in 23 eyes (92%) and remained detached 2 eyes (8%). Visual acuity after surgery was 0.1< 17 eyes, 0.4< 7 eyes. Visual acuity improved in 23 eyes (84%), remained the same in 2 eyes (8%). Conclusion Myopia and trauma are important risk factors for Rhegmatogenous Retinal Detachment. Majority of patients in this setting presented late with Rhegmatogenous Retinal Detachment and this was responsible for relatively poor visual outcomes despite good anatomical results after surgery. Proper screening of eyes at risk and education of patients is important for preventing visual loss due to retinal detachment.

Background: Endometriosis is a condition in which cells in the endometrium, layer of tissue normally covers uterine cavity, which grows outside to ovaries and other pelvic organs [1-4]. That may happen chronic pelvic pain, adhesion and pelvic organs dysfunction which leads to infertility later life [1-4]. In worldwide, 19-45 aged women have endometriosis, which is counted for 176 million, from 44% women have ovarian endometrioma [5]. In our country, 56% women received laparoscopic surgery due to ovarian cysts, which is diagnosed endometrioma. In recent years, ovarian endometriosis treated by synthetic progestin, gonadotropin analogues, combined contraceptive pills, intra-uterine device containing with progestin, and non-steroid anti-inflammatory drugs and laparoscopic surgeries [6, 7]. Serum antimullerian hormone (AMH) is key marker to define ovarian reserve, which correlates ovarian number of antral follicle counts [6, 7]. Material and Methods: We studied 129 patients who has diagnosed with ovarian endometrioma, aged 20-46 years, using case-control study design. There are 4 groups with medication and surgeries.
Approval for the study was obtained from the review board and the ethics committee of MNUMS. All the recruited patients provided their informed written consents. Results: When treatment groups were compared, level of AMH before synthetic progestin therapy was 3.48±0.9 and after it 3.41±1.0 (p-0.456), and that was before non-steroid anti-inflammatory drugs 3.68±0.8 and after it 3.11±0.8 ng/ml (p-0.212). Before laparoscopic surgeries for severe endometrioma, average level of AMH was 2.3±1.8ng/ml for synthetic progestin therapy group and it was 1.68±0.2ng/ml (p-0.007) after surgical peeling of endometrioma. For patients of 4th group who had not taking oral synthetic progestin before laparoscopic surgeries average level of AMH was 3.11±1.88 ng/ml before surgery and it became 2.21±0.28 ng/ml (p-0.005). Level of СА-125 marker was before medical therapy for group 1 was 37,9±5,25 IU/ml and after therapy - 20,6±2,03 IU/ml. For group 2 it was 69,9±9,79IU/ml and 35.1±6.76 IU/ml respectively. Average level for group 4 before surgical treatment it was 96.6±36.6 IU/ml, and after surgery became 25.71±2.96 IU/ml, and that for group 3 was before surgery 102±29.1 IU/ml and decreased after surgery to 29.2±4.15 IU/ml.
There are significant reduction of pain in patients who received synthetic progestin (p=0.001) groups. Serum AMH were 3.48±0.9 before treatment and 3.41±1.0 after treatment respectively (p=0.456). Prior treatment of laparoscopic surgery with progestin 3 months, it decreases abdominal lower pain (p=0.001) and dysmenorrhea (p=0.001). Serum AMH level were 3.11±1.8 before surgery and 2.21±0.2 after surgery,respectively, (p=0.005). Conclusion
1. There were little decrease in level of antimullerian hormone and less risk for ovarian reserve when mild endometrioma was treated with synthetic progestin and non-steroid anti-inflammatory drugs in two groups.
When severe and middle degree of endometrioma was treated with laparoscopic surgery there were significant decrease of antimullerian hormone, but it was less in group that had synthetic progestin therapy before surgery and it was more effective that surgical therapy without preparation.
2. Comparison of Serum level of СА-125, marker of ovarian tumor, was decreased less in group of non-steroid anti-inflammatory drugs, and was decreased more or it was more effective.

Introduction : In the last years other country scientists told about not only determine infant weights, need to interest correlation between maternal weight, height and infant weight. In our country few research articles posted about anthropometry of obstetrics and gynecology. Our study aim is determine maternal weight, infant weight, placenta weight and assess factors affecting roles on maternal story of “Amgalan” Maternity Hospital in 2014-2015. Goal: The current study aimed at assessing maternal weight, infant weight, placenta weight and evaluating the effect of factors leading to it. Materials and Methods: The data was already collected from “Amgalan” Maternity Hospital using maternal history and record and it was collected measuring general physical characteristics such as body weight and height, infant weight, placenta weight and body circumferences. We used retrospective method and collected statistical data was analyzed using SPSS 21.0 software. Results: Of total 964 study participants aged 18-45. The average age of participants was 29.6 ± 5.8 years old and 49.7% (n=479) was working during pregnancy, 45.7% (n=441) hadn’t works, 4.6% (n=44) was student. The average weight of mothers was 75.4±11.5, weight of infants was 3439.5±456, weight of placenta was 685±129. The following factors affected maternal and infant weights: lower education, working, early and late pregnancy complication. Maternal weight had a low direct correlation with infant weight (r=0.267, p<0.01) and placenta weight (r=0.208, p<0.01). In our study maternal height had a low direct correlation with infant weight(r=0.173, p<0.01) and infant weight had a moderate direct correlation with placenta weight (r=0.376, p<0.01). Conclusions
1. The average maternal weight was 75.4±11.5, infant weight was 3539.5±456, placenta weight was 685±129.
2. The following factors affected maternal and infant weights: lower education, working status, early and late pregnancy complications.
3. Maternal weight had a little direct correlation with infant weight (r=0.267, p<0.01) and placenta weight (r=0.208, p<0.01).