Kikuchi-Fujimoto’s disease (KFD), histologically described as necrotising histiocytic lymphadenitis, is a
benign self-limiting disease though a few fatalities have been reported. It is uncommon outside Japan
and other Asiatic countries and thus lack of awareness among physicians may have led to its under-
diagnosis or misdiagnosis as lymphoma or tuberculosis. It has recently gained importance due to its
possible association with autoimmune disorders and viral infections especially Infectious Mononucleo-
sis. Here we report a young South Indian man with fever, upper respiratory tract infection and tender
cervical lymphadenopathy confirmed by biopsy to be KFD. He also had coexistent scrub typhus infec-
tion evident by positive markers during the course of illness, which became negative six weeks later.
Supportive management with non-steroidal anti-inflammatory agents has led to complete remission of
symptoms. Association between KFD and scrub typhus has not been previously reported.