1.Short-acting β2-agonist prescription patterns and clinical outcomes in Malaysia: A nationwide cohort of the SABINA III study
Andrea Ban Yu-Lin ; Paranthaman Vengadasalam ; Sri Wahyu Taher ; Mohd Arif Mohd Zim ; Syazatul Syakirin Sirol Aah ; Ummi Nadira Daut ; Irfhan Ali Hyder Ali ; Lalitha Pereirasamy ; Azza Omar ; Aishah Ibrahim ; Noor Aliza Mohd Tarekh ; Swee Kim Chan ; Norsiah Ali ; Nor Azila Mohd Isa ; Husni Hussain ; Noraziah Abdul Karim ; Vieshal Raja Gopal ; Sue Yin Chiam ; Maarten J.H.I. Beekman
Malaysian Family Physician 2023;18():1-17
Introduction: SABINA III assessed short-acting β2-agonist (SABA) prescription patterns and their
association with asthma-related outcomes globally. Herein, we examined SABA prescription and
clinical outcomes in the Malaysian cohort of SABINA III.
Methods: In this observational, cross-sectional study, patients (12 years) were recruited between
July and December 2019 from 15 primary and specialty care centres in Malaysia. Prescribed asthma
treatments and severe exacerbation history within 12 months prior and asthma symptom control
during the study visit were evaluated. Associations of SABA prescription with asthma control and
severe exacerbation were analysed using multivariable regression models.
Results: Seven hundred thirty-one patients (primary care, n=265 [36.3%]; specialty care, n=466
[63.7%]) were evaluated. e prevalence of SABA over-prescription (3 SABA prescriptions/year)
was 47.4% (primary care, 47.1%; specialty care, 47.6%), 51.8% and 44.5% among all patients and
patients with mild and moderate-to-severe asthma, respectively. Altogether 9.0% (n=66) purchased
SABA without a prescription; among them, 43.9% (n=29) purchased 3 inhalers. e mean
(standard deviation) number of severe asthma exacerbations was 1.38 (2.76), and 19.7% (n=144)
and 25.7% (n=188) had uncontrolled and partly controlled symptoms, respectively. Prescriptions
of 3 SABA inhalers (vs 1–2) were associated with lower odds of at least partly controlled asthma
(odds ratio=0.42; 95% condence interval [CI]=0.27–0.67) and higher odds of having severe
exacerbation(s) (odds ratio=2.04; 95% CI=1.44–2.89).
Conclusion: e prevalence of SABA over-prescription in Malaysia is high, regardless of the
prescriber type, emphasising the need for healthcare providers and policymakers to adopt latest
evidence-based recommendations to address this public health concern.
2.Traumatic Posterior Hip Dislocation in a Child: When is an Anterior Open Reduction Indicated? A Case Report
Harikrishnan KT ; Jamil K ; Abd Rasid AF ; Abdul Rashid AH ; Ibrahim S
Journal of Surgical Academia 2020;10(1):23-26
Traumatic Posterior Hip Dislocation in a Child: When is an Anterior Open Reduction Indicated? A Case Report
Traumatic hip dislocations in children are uncommon, occurring in about 5% of all dislocations in children. Neglected hip dislocations are rarer and pose a serious threat to the normal development of the hip with complications of avascular necrosis and unstable gait. Open reduction is usually required, but the most appropriate surgical approach has not been clearly defined. We reported a child with a traumatic posterior hip dislocation who was successfully treated through an anterior approach after a previously failed posterior open reduction. An anterior open reduction of the hip following a previous failed posterior open reduction is a safe procedure and avoids the likelihood of an iatrogenic injury to the sciatic nerve. Pre-operative imaging with a CT scan or MRI is required in neglected cases to visualise intra-articular bone fragments, which can prevent a concentric reduction.
3.Neonatal Clavicle Fracture: A Review of Fourteen Cases in East Coast Peninsular Malaysia
Awang MS ; Abdul Razak AH ; Che Ahmad A
The International Medical Journal Malaysia 2017;16(2):79-83
Introduction: The purpose of this study is to identify the incidence of clavicle fractures in newborn
associated with fetal, maternal and process of deliveries in Kuantan General Hospital from June 2012 until
January 2014. This study is to determine epidemiological data of clavicle fractures, maternal and baby risk
factors associated with clavicle fractures of newborn and its’ outcome. Methods: This is a prospective
study. 13 patients were identified to fulfill the inclusion criteria of the study. The data of
sociodemographic, associated fetal and maternal risk factors and the outcomes were recorded using
proforma. The statistical data analysis was done using SPSS 12.0. Results: Out of 20,257 live births at our
centre during the study period, 13 infants were diagnosed to have clavicle fractures, giving an incidence of
0.64 per 1000 live births. There were 5 (38.5%) left, 7 (53.8%) right and one (7.7%) bilateral fracture. All
fractures located at the mid shaft of the clavicle and none have associated brachial plexus injuries. All
infants were delivered through vaginal delivery (61.5%); five through assisted delivery (instrumental); 2
(15.4%) forcep and 3 (23.1%) vacuum. Two of the babies developed shoulder dystocia. The average birth
weight was 3371 grams (SD 0.269) and mean gestational age was 38.7 weeks (SD 1.16). Five of the mothers
(38.5%) were primigravida and eight (61.5%) were multigravida in which,7 (53.8%)were healthy without
other co-morbidty, 5 (38.5%) having gestational diabetis and one (7.7%) hypertension. The average maternal
weight was 62.0 kg and height 1.58 metres with average BMI of 24.16 (3.29SD). All eventually had a
complete recovery at 6 weeks with clinical and radiological evident of fracture union. Conclusions: In
conclusion, all patients with clavicle fractures were found following vaginal delivery. There were no
associations between neonatal clavicle fractures with maternal or baby risk factors. All fractures healed
without any complications.


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