Despite publishing and securing research grants being obligatory in research universities, the literature on the factors influencing academic productivity is relatively scarce. Thus, in this study, we aimed to determine the personal and behavioural-related factors that influence the culture of publishing and securing research grants among academicians with lower research-related performance. This cross-sectional study was conducted among 49 academic staff members of Universiti Kebangsaan Malaysia (UKM). A self-administered questionnaire consisting of personal, attitude and behavioural (barriers, perceived stress scale, work extrinsic and intrinsic motivation scale, psychological well-being scale, and basic needs satisfaction scale) questions were distributed during a workshop and online. Simple linear regression (SLR) analyses were performed for each variable, followed by multiple linear regression (MLR) to identify the associated factors of research output. After adjusting for covariates, having a doctoral degree (β=0.396, 95% CI=0.221-2.146, p<0.05) and integrated regulation (β=0.574, 95% CI=0.036-3.612, p<0.05) were found to be associated with research grant acquisition (R2=0.273). Moreover, increasing age (β=0.426, 95% CI=0.088-0.397, p<0.05), living alone (β=0.331, 95% CI=0.944-6.626, p<0.05), having a doctoral degree (β=0.248, 95% CI=0.174-6.747, p<0.05), environmental mastery (β=0.318, 95% CI=0.013-0.347, p<0.05), self-acceptance (β=0.284, 95% CI=0.010-0.242, p<0.05), satisfaction incompetence (β=0.273, 95% CI=0.001-0.200, p<0.05) and relatedness (β=0.280, 95% CI=0.001-0.116, p<0.05) were found to be the factors that influence the publications produced among participants (R2 =0.423). The findings of this study could be used by management to formulate effective strategies to increase the productivity of academics in their research-related performance.

Parenting children with autism spectrum disorder comes with challenges that impact parenting stress and quality of life, with social support being an influencing factor. The cultural context appears to influence associations between parenting stress, social support, and quality of life. There is a lack of reviews examining these associations in Asia. Thus, this review aims to provide an overview of the relationship between parenting stress, QOL and social support specific to the population in Asian countries. Systematic searches based on PRISMA guidelines were conducted on Medline, Web of Science, and Scopus, which found 26 eligible studies to be included in the review. Findings from the studies demonstrated social support, parenting stress, and quality of life to be significantly associated with each other directly and indirectly. They are also related to multiple variables like coping strategies and self-efficacy. In the future, data from a wider scope of Asian countries will be beneficial since most literature originated from China. Furthermore, more studies on potential moderator and mediator variables could be conducted.

Introduction: Breastfeeding is vital for child survival and development, yet its practices are influenced by cultural, social, and informational factors. There is inadequate data concerning breastfeeding knowledge, attitudes, and practices (KAP) among the Orang Asli in Malaysia. This study aims to assess the KAP related to breastfeeding among Orang Asli in Peninsular Malaysia. Methods: A cross-sectional study was carried out between July 2022 and November 2023 among Orang Asli women aged 18 years and older with at least one child. Respondents were selected from sub-ethnic groups across three main indigenous categories. Data were gathered through a structured questionnaire, administered by interviewers which covered socio-demographics, knowledge, attitudes, and practices. Descriptive statistics were used for analysis. Results: One hundred respondents participated in the study. The majority (89%) had practiced exclusive breastfeeding, and 90% intended to continue in the future. About 98% correctly recognized that adequate breastfeeding helps infants sleep better, and 94% knew that complementary feeding should begin at six months. But several cultural or misinformation-related beliefs persisted. For example, 42% believed colostrum should be discarded, and 49% thought breastfeeding should be stopped if the mother had cracked nipples. Overall, respondents demonstrated positive attitudes and consistent breastfeeding practices. Although 58% found exclusive breastfeeding tiring for the mother. Conclusion: Despite high breastfeeding rates and positive intentions, mixed feeding practices and misconceptions persist among Orang Asli mothers. Culturally sensitive, community-based education is needed to reinforce accurate breastfeeding knowledge and support exclusive breastfeeding practices.

Objectives: Premarital screening can reduce the risk of genetic disorders and sexually transmitted diseases by providing early detection before conception. College students represent a group of young adults with higher education who are approaching marriageable age. However, many students still lack a strong intention to undergo premarital screening in the future. Therefore, this study examines the factors influencing screening intentions among students at one of Indonesia’s leading universities, the State Islamic University (UIN) Jakarta. Methods: This study used a cross-sectional design, with a total sample of 563 college students obtained through a multistage random sampling technique. Descriptive statistics were used to summarize the data, and ordinal logistic regression was applied for hypothesis testing. Results: Among the 563 students, 97.0% indicated an intention to undergo premarital screening. The intention variable was classified into three levels: no/low (13.0%), moderate (43.5%), and high (43.5%). Ordinal logistic regression revealed that lower knowledge about premarital screening was significantly associated with a reduced intention to undergo screening (odds ratio [OR], 2.84; 95% confidence interval [CI], 1.58 to 5.10). In addition, negative attitudes toward premarital screening (OR, 2.85; 95% CI, 1.41 to 5.75), negative attitudes toward premarital screening (OR, 1.63; 95% CI, 1.12 to 2.37), and being enrolled in a non-health-related field of study (OR, 1.96; 95% CI, 1.04 to 3.68) were significantly linked to lower screening intentions. Conclusions Comprehensive premarital health education is essential for young adults, even those with a high level of formal education. Such education not only improves knowledge but also promotes more positive perceptions and attitudes toward premarital screening.

Background: Changes in cognitive function are associated with increased depression and decreased quality of life (QOL). This study aimed to determine the relationship between the characteristics of geriatric patients and anesthetic management with changes in postoperative cognitive function and QOL of geriatric patients undergoing elective surgery. Methods: This prospective observational analytic multicenter study included patients aged ≥60 years who underwent elective surgery in hospitals in Indonesia. We used the whole sampling method and performed follow-up 30 days after surgery. Data were analyzed using bivariate chi-square and multivariate regression tests with a confidence interval of 95% and α=5%. Results: Among the 933 geriatric patients included in this study 55.0%, females most (59.8%) received general anesthesia. Factors including age (p<0.001, B=-0.374, odds ratio [OR]=0.688), body mass index (BMI) (p<0.05, B=0.129, OR=1.138), and physical status based on American Society of Anesthesiologists (ASA) classification (p<0.001, B=-0.458, OR=0.633) were significantly associated with postoperative cognitive function. BMI (p<0.001, B=-0.218, OR=1.244), absence of comorbidities (p<0.05, B=-0.312, OR=0.732), regional anesthesia (p<0.05, B=0.606, OR=1.883), and changes in cognitive function (p<0.05, B=0.288, OR=1.334) were significantly correlated with changes in postoperative QOL. Conclusion Age, BMI, and ASA physical status were significantly associated with postoperative cognitive function in geriatric patients, whereas BMI, comorbidities, regional anesthesia, and changes in postoperative cognitive function were associated with QOL. These preoperative factors can predict postoperative cognitive function and QOL and may be useful during preoperative planning.

Kemunculan teknologi penyuntingan genom, terutamanya CRISPR/Cas9, telah mengubah dan merevolusikan landskap bidang genetik dan biologi molekul dengan begitu drastik. Sistem CRISPR/Cas9 diadaptasi daripada sistem adaptasi imuniti bakteria, menggunakan enzim Cas9 yang dipandu oleh sgRNA untuk penyingkiran gen atau penyuntingan genom secara jitu. Walau bagaimanapun, cabaran seperti kesan luar sasaran (off-target effects) telah mendorong pembangunan beberapa varian Cas9 seperti dCas9. dCas9 diubah suai untuk tidak memiliki sebarang aktiviti endonuklease dan kini dCas9 telah digunakan untuk pelbagai aplikasi yang melangkaui fungsi tradisional CRISPR/Cas9 sebagai kaedah pengeditan genom. Selain itu, teknologi terkini penyuntingan perdana (prime editing) telah menggabungkan enzim Cas9 yang diubahsuai bersama enzim transkriptase berbalik (reverse transcriptase) untuk meningkatkan lagi tahap keberkesanan penyuntingan genom secara jitu. Walaupun wujud kerisauan terhadap pertimbangan etika dan kebimbangan terkait keselamatan, namun teknologi ini menjanjikan dampak yang besar di dalam menangani penyakit genetik serta aplikasi dalam bidang perubatan jitu (precision medicine). Memahami dan mengoptimumkan potensi CRISPR/Cas9 dan teknologi penyuntingan perdana menandakan bermula era baharu dalam bidang penyelidikan berkaitan biologi dan perubatan, dan seterusnya menyediakan satu platform untuk penyuntingan genom yang tepat dan pengawalseliaan proses transkripsi gen.

Background: Changes in cognitive function are associated with increased depression and decreased quality of life (QOL). This study aimed to determine the relationship between the characteristics of geriatric patients and anesthetic management with changes in postoperative cognitive function and QOL of geriatric patients undergoing elective surgery. Methods: This prospective observational analytic multicenter study included patients aged ≥60 years who underwent elective surgery in hospitals in Indonesia. We used the whole sampling method and performed follow-up 30 days after surgery. Data were analyzed using bivariate chi-square and multivariate regression tests with a confidence interval of 95% and α=5%. Results: Among the 933 geriatric patients included in this study 55.0%, females most (59.8%) received general anesthesia. Factors including age (p<0.001, B=-0.374, odds ratio [OR]=0.688), body mass index (BMI) (p<0.05, B=0.129, OR=1.138), and physical status based on American Society of Anesthesiologists (ASA) classification (p<0.001, B=-0.458, OR=0.633) were significantly associated with postoperative cognitive function. BMI (p<0.001, B=-0.218, OR=1.244), absence of comorbidities (p<0.05, B=-0.312, OR=0.732), regional anesthesia (p<0.05, B=0.606, OR=1.883), and changes in cognitive function (p<0.05, B=0.288, OR=1.334) were significantly correlated with changes in postoperative QOL. Conclusion Age, BMI, and ASA physical status were significantly associated with postoperative cognitive function in geriatric patients, whereas BMI, comorbidities, regional anesthesia, and changes in postoperative cognitive function were associated with QOL. These preoperative factors can predict postoperative cognitive function and QOL and may be useful during preoperative planning.

Objectives: Premarital screening can reduce the risk of genetic disorders and sexually transmitted diseases by providing early detection before conception. College students represent a group of young adults with higher education who are approaching marriageable age. However, many students still lack a strong intention to undergo premarital screening in the future. Therefore, this study examines the factors influencing screening intentions among students at one of Indonesia’s leading universities, the State Islamic University (UIN) Jakarta. Methods: This study used a cross-sectional design, with a total sample of 563 college students obtained through a multistage random sampling technique. Descriptive statistics were used to summarize the data, and ordinal logistic regression was applied for hypothesis testing. Results: Among the 563 students, 97.0% indicated an intention to undergo premarital screening. The intention variable was classified into three levels: no/low (13.0%), moderate (43.5%), and high (43.5%). Ordinal logistic regression revealed that lower knowledge about premarital screening was significantly associated with a reduced intention to undergo screening (odds ratio [OR], 2.84; 95% confidence interval [CI], 1.58 to 5.10). In addition, negative attitudes toward premarital screening (OR, 2.85; 95% CI, 1.41 to 5.75), negative attitudes toward premarital screening (OR, 1.63; 95% CI, 1.12 to 2.37), and being enrolled in a non-health-related field of study (OR, 1.96; 95% CI, 1.04 to 3.68) were significantly linked to lower screening intentions. Conclusions Comprehensive premarital health education is essential for young adults, even those with a high level of formal education. Such education not only improves knowledge but also promotes more positive perceptions and attitudes toward premarital screening.

An Evidence-Based Treatment Guide for Trauma from Occlusion: Essential Guidelines for Dental Students Trauma resulting from occlusion is a common clinical issue that can lead to significant discomfort, dysfunction, and long-term dental complications. This article is designed to offer a simplified, evidence-based overview of the pathophysiology of occlusal trauma, diagnostic approaches, and a treatment guide, making the management of occlusal trauma more accessible and easier to understand. Emphasis is placed on the importance of an individualized treatment planning, offering clinicians practical insights to optimize outcomes and minimize the adverse effects. The findings support the need for evidence-based decision-making in the management of occlusal trauma, ensuring both short-term relief and long-term dental health preservation.

Objectives: Premarital screening can reduce the risk of genetic disorders and sexually transmitted diseases by providing early detection before conception. College students represent a group of young adults with higher education who are approaching marriageable age. However, many students still lack a strong intention to undergo premarital screening in the future. Therefore, this study examines the factors influencing screening intentions among students at one of Indonesia’s leading universities, the State Islamic University (UIN) Jakarta. Methods: This study used a cross-sectional design, with a total sample of 563 college students obtained through a multistage random sampling technique. Descriptive statistics were used to summarize the data, and ordinal logistic regression was applied for hypothesis testing. Results: Among the 563 students, 97.0% indicated an intention to undergo premarital screening. The intention variable was classified into three levels: no/low (13.0%), moderate (43.5%), and high (43.5%). Ordinal logistic regression revealed that lower knowledge about premarital screening was significantly associated with a reduced intention to undergo screening (odds ratio [OR], 2.84; 95% confidence interval [CI], 1.58 to 5.10). In addition, negative attitudes toward premarital screening (OR, 2.85; 95% CI, 1.41 to 5.75), negative attitudes toward premarital screening (OR, 1.63; 95% CI, 1.12 to 2.37), and being enrolled in a non-health-related field of study (OR, 1.96; 95% CI, 1.04 to 3.68) were significantly linked to lower screening intentions. Conclusions Comprehensive premarital health education is essential for young adults, even those with a high level of formal education. Such education not only improves knowledge but also promotes more positive perceptions and attitudes toward premarital screening.