Case Report Open Access 15 Primary renal lymphoma without widespread nodal disease is a rare entity. Its diagnosis is challenging as it can mimic other more common renal malignancies such as renal cell carcinoma (RCC) or upper tract urothelial carcinoma (UTUC). We report a 65 -year-old male who presented a month history of bilateral flank pain. Initial computed tomography urography showed a soft tissue enhancing lesion with irregular margin in the left renal pelvis, extending distally to the left proximal ureter, suspicious of UTUC. He underwent laparoscopic left radical nephrectomy and bladder cuff excision. However, histopathology came back as a left renal in situ follicular B -cell neoplasm (ISFN). He was subsequently referred to haematology service for further management. This case report aims to raise awareness of ISFN and to consider renal lymphoma in a patient presenting with a renal mass. A high index of suspicion and judicious use of tissue biopsy can avoid unnecessary and potentially morbid surgical interventions

Case Report Open Access 15 Primary renal lymphoma without widespread nodal disease is a rare entity. Its diagnosis is challenging as it can mimic other more common renal malignancies such as renal cell carcinoma (RCC) or upper tract urothelial carcinoma (UTUC). We report a 65 -year-old male who presented a month history of bilateral flank pain. Initial computed tomography urography showed a soft tissue enhancing lesion with irregular margin in the left renal pelvis, extending distally to the left proximal ureter, suspicious of UTUC. He underwent laparoscopic left radical nephrectomy and bladder cuff excision. However, histopathology came back as a left renal in situ follicular B -cell neoplasm (ISFN). He was subsequently referred to haematology service for further management. This case report aims to raise awareness of ISFN and to consider renal lymphoma in a patient presenting with a renal mass. A high index of suspicion and judicious use of tissue biopsy can avoid unnecessary and potentially morbid surgical interventions

Colorectal cancer (CRC) has become a significant worldwide health issue among Malaysians. It has become the second most common disease among men and women, with an increased mortality rate in recent years. CRC cases can be reduced with a healthy diet by increasing natural product intake. However, today most of the commercialized natural products for CRC prevention are imported and costly, which makes 80% of the Malaysian population could hardly afford them due to low and middle household income. Therefore, the present study summarizes the list of local tropical natural products that have remarkable medicinal properties effective on CRC, which are easily accessible for Malaysians, ways to consume them at home, and the economic prospects. This narrative review reviews the latest natural products' properties against CRC, excluding the plants examined in previous studies. The keywords utilized to identify the relevant articles were “Malaysia," "Colorectal Cancer," “Natural products," “Anticancer," "Antidiarrheal," "Mucositis," and "Vomit/Nausea" through PubMed, ScienceDirect, and Google Scholar. Conclusion: In conclusion, the locally available natural products have excellent medicinal properties against colorectal cancer with enormous potential medicinal properties in treating CRC and chemotherapy-induced toxicity that Malaysians can use to improve their well-being.

The incidence of intradermal nevus in the externalauditory canal is uncommon. We herein are describing acase of 60-year-old lady who presented with foreign bodysensation in the right external ear canal (EAC) with milddiscomfort and ear bleed during ear picking. Otoscopicexamination revealed hyperpigmented mass on the floorof the outer two third of EAC. Complete excisional biopsyof the mass resulted in histopathology findings ofintradermal nevus. Despite the fact that the disease is notalarming, the possibilities of benign melanocytic nevitransformation into malignant lesions such as melanomaneed to be ruled out.