Objective:To explore the effect of early cardiac rehabilitation strategies on functional prognosis in patients with acute coronary syndrome(ACS)who received coronary artery bypass grafting(CABG).Methods:A total of 158 ACS patients who underwent CABG in the First Affiliated Hospital of Xinjiang Medical University between Jan-uary 2022 and December 2023 were included in this randomized control trial.Participants were randomly divided in-to early cardiac rehabilitation group(n=79)and control group(n=79).Patients in the control group received con-ventional nursing measures,while those in the early rehabilitation group received additional early cardiac rehabilita-tion strategies.Both groups were continuously intervened for 1 month.We compared the changes in cardiac function[left ventricular end-diastolic diameter(LVEDd),left ventricular ejection fraction(LVEF)and 6-miniute walk distance(6MWD)],myocardial injury markers[cardiac troponin I(cTnI),N-terminal pro brain natriuretic pep-tide(NT-proBNP)and cystatin C(CysC)],quality of life[China questionnaire of quality of life in patients with cardiovascular diseases(CQQC)score],ability of daily living(ADL)score,and incidence of major adverse cardio-vascular events(MACE)during the intervention period between two groups.Results:Compared to participants in the control group,those in the early rehabilitation group had significantly higher LVEF[(53.31±1.73)％vs.(52.09±1.72)％,P＜0.001],6MWD[(407.60±25.00)m vs.(395.17±19.20)m,P＜0.001],CQQC score[(84.75±8.44)points vs.(75.98±7.60)points,P＜0.001]and ADL score[(88.67±2.58)points vs.(78.87±3.05)points,P＜0.001],and significantly lower LVEDd[(47.02±2.28)mm vs.(52.93±2.57)mm,P＜0.001],cTnI[(0.48±0.04)μg/L vs.(0.52±0.05)μg/L,P＜0.001],NT-proBNP[(213.74±23.54)ng/ml vs.(287.26±41.99)ng/ml,P＜0.001],CysC[(0.87±0.08)mg/L vs.(1.06±0.10)mg/L,P＜0.001]and in-cidence of MACE(9.21％vs.24.32％,P=0.013).Conclusion:Early cardiac rehabilitation strategy may improve cardiac function and prognosis in patients with acute coronary syndrome who received coronary artery bypass grafting.

Objective:To explore the effect of early cardiac rehabilitation strategies on functional prognosis in patients with acute coronary syndrome(ACS)who received coronary artery bypass grafting(CABG).Methods:A total of 158 ACS patients who underwent CABG in the First Affiliated Hospital of Xinjiang Medical University between Jan-uary 2022 and December 2023 were included in this randomized control trial.Participants were randomly divided in-to early cardiac rehabilitation group(n=79)and control group(n=79).Patients in the control group received con-ventional nursing measures,while those in the early rehabilitation group received additional early cardiac rehabilita-tion strategies.Both groups were continuously intervened for 1 month.We compared the changes in cardiac function[left ventricular end-diastolic diameter(LVEDd),left ventricular ejection fraction(LVEF)and 6-miniute walk distance(6MWD)],myocardial injury markers[cardiac troponin I(cTnI),N-terminal pro brain natriuretic pep-tide(NT-proBNP)and cystatin C(CysC)],quality of life[China questionnaire of quality of life in patients with cardiovascular diseases(CQQC)score],ability of daily living(ADL)score,and incidence of major adverse cardio-vascular events(MACE)during the intervention period between two groups.Results:Compared to participants in the control group,those in the early rehabilitation group had significantly higher LVEF[(53.31±1.73)％vs.(52.09±1.72)％,P＜0.001],6MWD[(407.60±25.00)m vs.(395.17±19.20)m,P＜0.001],CQQC score[(84.75±8.44)points vs.(75.98±7.60)points,P＜0.001]and ADL score[(88.67±2.58)points vs.(78.87±3.05)points,P＜0.001],and significantly lower LVEDd[(47.02±2.28)mm vs.(52.93±2.57)mm,P＜0.001],cTnI[(0.48±0.04)μg/L vs.(0.52±0.05)μg/L,P＜0.001],NT-proBNP[(213.74±23.54)ng/ml vs.(287.26±41.99)ng/ml,P＜0.001],CysC[(0.87±0.08)mg/L vs.(1.06±0.10)mg/L,P＜0.001]and in-cidence of MACE(9.21％vs.24.32％,P=0.013).Conclusion:Early cardiac rehabilitation strategy may improve cardiac function and prognosis in patients with acute coronary syndrome who received coronary artery bypass grafting.