1.Evaluation of anorectal dynamics in children with tethered cord syndrome before and after surgery and its clinical significance.
Qian-Cheng XU ; Zhi-Peng SHEN ; Pei-Liang ZHANG ; Jing-Yi FENG ; Mi-Zu JIANG
Chinese Journal of Contemporary Pediatrics 2025;27(5):563-567
OBJECTIVES:
To investigate the characteristics and clinical significance of anorectal manometry measurements in children with tethered cord syndrome (TCS) before and after surgery.
METHODS:
A retrospective study was conducted on 44 children with TCS treated at the Children's Hospital of Zhejiang University School of Medicine from January 2022 to September 2023. These patients were divided into effective subgroup (n=34) and non-effective subgroup (n=10) based on postoperative symptom improvement. Additionally, 34 children with functional constipation were selected as a control group. Baseline data and manometry measurements were compared between the preoperative TCS group and the control group, as well as between the non-effective and effective subgroups.
RESULTS:
The TCS group had lower short contraction time and defecation relaxation rate compared to the control group (P<0.05), while defecation residual pressure and maximum rectal tolerable threshold were higher than the control group (P<0.05). The length of the anal canal in the high-pressure zone in the effective subgroup was greater postoperatively than preoperatively (P<0.05), and the initial rectal sensation threshold decreased postoperatively (P<0.05). The non-effective subgroup had lower preoperative maximum rectal expulsion pressure compared to the effective subgroup (P<0.05). Postoperative rectal anal inhibition reflex values in the effective subgroup were higher than those in the non-effective subgroup (P<0.05).
CONCLUSIONS
There are some differences in anorectal dynamics between children with TCS and those with functional constipation. Maximum rectal expulsion pressure may be a key predictor of surgical outcomes. Surgery can alter certain defecation functions in some children.
Humans
;
Male
;
Anal Canal/physiopathology*
;
Female
;
Rectum/physiopathology*
;
Child
;
Child, Preschool
;
Retrospective Studies
;
Manometry
;
Neural Tube Defects/physiopathology*
;
Infant
;
Defecation
;
Adolescent
;
Constipation/physiopathology*
;
Clinical Relevance
2.Standardized surgical procedure of proximally extended resection and sphincter-preserving surgery (Tianhe procedure®) for rectal cancer after radiotherapy (2025 version).
Chinese Journal of Gastrointestinal Surgery 2025;28(7):707-716
Tianhe procedure® is a functional sphincter-preserving surgical approach developed for rectal cancer patients following radiotherapy. This technique involves extended proximal resection of the colon beyond the pelvic cavity, followed by anastomosis of the non-irradiated proximal colon to the distal rectum or anal canal. This strategy aims to reduce the incidence of anastomotic complications and postoperative bowel dysfunction. However, there is currently a lack of standardized practice guideline for implementing Tianhe procedure® in China. Therefore, the Chinese Radiation Intestinal Injury Research Group, the Colorectal Surgery Group of Surgery Branch of the Chinese Medical Association, the Anorectal Branch of Chinese Medical Doctor Association, the Colorectal Cancer Committee of the Chinese Medical Doctor Association, and the Colorectal Cancer Committee of China Anti-cancer Association, and the Gastrointestinal Surgical Branch of Guangdong Medical Doctor Association, have jointly convened a panel of national experts to discuss and establish this standardized surgical procedure. This standard, based on the latest evidence from literature, research advancements, and expert experience, focuses on key aspects of the Tianhe procedure®, including its precise definition, indications, critical procedural steps, postoperative complications, and functional rehabilitation strategies. It aims to promote standardized implementation and broader clinical adoption of this innovative surgical technique.
Humans
;
Rectal Neoplasms/radiotherapy*
;
Anal Canal/surgery*
;
Anastomosis, Surgical/methods*
;
Organ Sparing Treatments/methods*
;
Rectum/surgery*
;
Postoperative Complications/prevention & control*
;
Digestive System Surgical Procedures/methods*
3.Indocyanine Green (ICG) fluorescence in the assessment of vascularity of anastomotic margins in colorectal surgery in a Lower Middle-Income Country (LMIC) hospital
Michael Geoffrey L. Lim ; Marc Paul J. Lopez ; Mark Augustine S. Onglao ; Marie Dione P. Sacdalan ; Hermogenes J. Monroy, III
Acta Medica Philippina 2024;58(16):8-13
Background and Objective:
One of the uses of indocyanine green (ICG) in the surgical field is the evaluation of the anastomotic margins in colorectal surgery. This is of particular importance because fluorescence imaging may aid in detecting vascular compromise, allowing the surgeon to change the resection margin thereby decreasing the chance of an anastomotic leak. To date, there has been no study with its use locally. This study aimed to determine whether the use of ICG can safely identify if the margins of resection are well-vascularized in patients undergoing left-sided colon or rectal surgery, which in turn may reduce anastomotic leak rates.
Methods:
Through a retrospective study design, the investigators gathered data of patients who underwent left-sided colon or rectal surgery. The groups were divided into those with and without the use of ICG and a comparative data on the anastomotic leak rates were analyzed.
Results:
Eighty-six (86) patients with similar patient characteristics, tumor staging, and surgical approach were compared. Both the leak rates identified during the initial hospital stay and at 30 days post-operatively were lower in those where ICG was used (p=0.035, p=0.047, respectively) than those where ICG was not used.
Conclusion
ICG fluorescence imaging may reduce the anastomotic leak rates in patients undergoing colorectal surgery.
indocyanine green
;
colon
;
rectum
;
colorectal surgery
;
anastomosis, surgical
;
anastomotic leak
4.Analysis of the causes of long-standing pelvic anterior sacral space infection and discussion of management techniques.
Gang Cheng WANG ; Hong Le LI ; Yang LIU ; Xiang Hao GU ; Rui Xia LIU ; Rui FENG ; You Cai WANG ; Ying Jun LIU ; Guo Qiang ZHANG ; Zhi ZHANG ; Hong Li WANG ; Fang WANG ; Yan ZHANG
Chinese Journal of Oncology 2023;45(3):273-278
Objective: To investigate the causes and management of long-term persistent pelvic presacral space infection. Methods: Clinical data of 10 patients with persistent presacral infection admitted to the Cancer Hospital of Zhengzhou University from October 2015 to October 2020 were collected. Different surgical approaches were used to treat the presacral infection according to the patients' initial surgical procedures. Results: Among the 10 patients, there were 2 cases of presacral recurrent infection due to rectal leak after radiotherapy for cervical cancer, 3 cases of presacral recurrent infection due to rectal leak after radiotherapy for rectal cancer Dixons, and 5 cases of presacral recurrent infection of sinus tract after adjuvant radiotherapy for rectal cancer Miles. Of the 5 patients with leaky bowel, 4 had complete resection of the ruptured nonfunctional bowel and complete debridement of the presacral infection using an anterior transverse sacral incision with a large tipped omentum filling the presacral space; 1 had continuous drainage of the anal canal and complete debridement of the presacral infection using an anterior transverse sacral incision. 5 post-Miles patients all had debridement of the presacral infection using an anterior transverse sacral incision combined with an abdominal incision. The nine patients with healed presacral infection recovered from surgery in 26 to 210 days, with a median time of 55 days. Conclusions: Anterior sacral infections in patients with leaky gut are caused by residual bowel secretion of intestinal fluid into the anterior sacral space, and in post-Miles patients by residual anterior sacral foreign bodies. An anterior sacral caudal transverse arc incision combined with an abdominal incision is an effective surgical approach for complete debridement of anterior sacral recalcitrant infections.
Humans
;
Reinfection
;
Rectum/surgery*
;
Rectal Neoplasms/surgery*
;
Drainage
;
Anal Canal/surgery*
;
Pelvic Infection
5.Difficulties and challenges of pelvic exenteration in locally advanced rectal cancer.
Chinese Journal of Gastrointestinal Surgery 2023;26(3):215-221
In recent years, with advances in pelvic oncology and surgical techniques, surgeons have redefined the boundaries of pelvic surgery. Combined pelvic exenteration is now considered the treatment of choice for some patients with locally advanced and locally recurrent rectal cancer, but it is only performed in a few hospitals in China due to the complexity of the procedure and the large extent of resection, complications, and high perioperative mortality. Although there have been great advances in oncologic drugs and surgical techniques and equipment in recent years, there are still many controversies and challenges in the preoperative assessment of combined pelvic organ resection, neoadjuvant treatment selection and perioperative treatment strategies. Adequate understanding of the anatomical features of the pelvic organs, close collaboration of the clinical multidisciplinary team, objective assessment and standardized preoperative combination therapy creates the conditions for radical surgical resection of recurrent and complex locally advanced rectal cancer, while the need for rational and standardized R0 resection still has the potential to bring new hope to patients with locally advanced and recurrent rectal cancer.
Humans
;
Pelvic Exenteration/methods*
;
Neoplasm Recurrence, Local/surgery*
;
Rectum/surgery*
;
Rectal Neoplasms/surgery*
;
Pelvis/surgery*
;
Treatment Outcome
;
Retrospective Studies
6.Advances in tumor regression patterns and safe distance of distal resection margin after neoadjuvant therapy for rectal cancer.
Ye WANG ; Zheng LOU ; Rong Gui MENG ; Li Qiang JI ; Shu Yuan LI ; Kuo ZHENG ; Lu JIN ; Hai Feng GONG ; Lian Jie LIU ; Li Qiang HAO ; Wei ZHANG
Chinese Journal of Gastrointestinal Surgery 2023;26(3):302-306
Neoadjuvant therapy has been widely applied in the treatment of rectal cancer, which can shrink tumor size, lower tumor staging and improve the prognosis. It has been the standard preoperative treatment for patients with locally advanced rectal cancer. The efficacy of neoadjuvant therapy for rectal cancer patients varies between individuals, and the results of tumor regression are obviously different. Some patients with good tumor regression even achieve pathological complete response (pCR). Tumor regression is of great significance for the selection of surgical regimes and the determination of distal resection margin. However, few studies focus on tumor regression patterns. Controversies on the safe distance of distal resection margin after neoadjuvant treatment still exist. Therefore, based on the current research progress, this review summarized the main tumor regression patterns after neoadjuvant therapy for rectal cancer, and classified them into three types: tumor shrinkage, tumor fragmentation, and mucin pool formation. And macroscopic regression and microscopic regression of tumors were compared to describe the phenomenon of non-synchronous regression. Then, the safety of non-surgical treatment for patients with clinical complete response (cCR) was analyzed to elaborate the necessity of surgical treatment. Finally, the review studied the safe surgical resection range to explore the safe distance of distal resection margin.
Humans
;
Neoadjuvant Therapy/methods*
;
Margins of Excision
;
Treatment Outcome
;
Rectal Neoplasms/pathology*
;
Rectum/pathology*
;
Neoplasm Staging
;
Retrospective Studies
7.Dong's extraordinary point needling technique combined with medication for postoperative complications of anal fistula: a randomized controlled trial.
Yan FU ; Yue XU ; Hai-Xia WU ; Shan-Shan WANG
Chinese Acupuncture & Moxibustion 2023;43(8):916-920
OBJECTIVE:
To observe the effect of Dong's extraordinary point needling technique on postoperative complications of anal fistula.
METHODS:
A total of 241 patients undergoing anal fistula surgery were randomly divided into an observation group (121 cases, 3 cases dropped off) and a control group (120 cases, 2 cases dropped off). The patients in the control group were treated with intramuscular injection of compound diclofenac sodium injection and oral administration of tamsulosin hydrochloride sustained release capsules. In addition to the treatment in the control group, the patients in the observation group were treated with Daoma needling technique at the "Sanqi points" (Qimen point, Qijiao point, and Qizheng point) combined with Dongqi needling technique at "Sanhuang points" (sub-Tianhuang point, Dihuang point, Renhuang point), with each session lasting 30 min. The treatment in the two groups both started on the first day after surgery, and was given once daily for 14 consecutive days. Visual analog scale (VAS) score was compared between the two groups on postoperative day 1, 7, and 14; bladder residual urine volume, spontaneous voiding volume, and urinary catheterization frequency were assessed after treatment on postoperative day 1; and anorectal dynamic indexes (anal canal resting pressure, rectal resting pressure, maximum squeeze pressure of the anal canal, and minimum rectal sensory threshold) were evaluated before surgery and on postoperative day 4. Clinical efficacy was assessed in both groups one month after surgery.
RESULTS:
On postoperative day 7 and 14, the VAS scores of both groups were lower than those on postoperative day 1 (P<0.05), and the VAS scores in the observation group were lower than those in the control group (P<0.05). The bladder residual urine volume and urinary catheterization frequency in the observation group were lower than those in the control group (P<0.05), while the spontaneous voiding volume was higher than that in the control group (P<0.05). On postoperative day 4, the anal canal resting pressure, maximum squeeze pressure of the anal canal, and the minimum rectal sensory threshold were lower than preoperative values (P<0.05), while the rectal resting pressure was higher than preoperative value (P<0.05) in both groups. The anal canal resting pressure, maximum squeeze pressure of the anal canal, and minimum rectal sensory threshold were lower than those in the control group, and the rectal resting pressure was higher than that in the control group (P<0.05). The effective rate was 93.2% (110/118) in the observation group, which was higher than 84.7% (100/118) in the control group (P<0.05).
CONCLUSION
Dong's extraordinary point needling technique could reduce postoperative pain, alleviate urinary retention, and improve defecation in patients undergoing anal fistula surgery.
Humans
;
Rectum
;
Rectal Fistula/surgery*
;
Anal Canal/surgery*
;
Treatment Outcome
;
Anus Diseases
;
Postoperative Complications/etiology*
;
Acupuncture Points
8.Chinese expert consensus on definition and terminology of colon and rectum: mesentery, fascia, and space (2023 edition).
Chinese Journal of Gastrointestinal Surgery 2023;26(6):529-535
Anatomy is the foundation of surgery. However, traditional anatomical concepts based on autopsy are no longer sufficient to guide the development of modern surgery. With the advancement of histology and embryology and application of high-resolution laparoscopic technology, surgical anatomy has gradually developed. Meanwhile, some important concepts and terms used to guide surgery have emerged, including: mesentery, fascia, and space. The confusing, controversial, and even inaccurate definitions and anatomical terms related to colorectal surgery seriously affect academic communication and the training of young surgeons. Therefore, the Chinese Society of Colorectal Surgeons, the Chinese Society of Colorectal Surgery, National Health Commission Capacity Building and Continuing Education Center, and China Sexology Association of Colorectal Functional Surgery organized colorectal surgeons to make consensus on the definition and terminology of mesentery, fascia, and space related to colon and rectum, to promote surgeons' understanding of modern anatomy related to colorectal surgery and promote academic communication.
Humans
;
Rectum/surgery*
;
Consensus
;
Mesentery/anatomy & histology*
;
Fascia/anatomy & histology*
;
Colorectal Neoplasms
9.Endometrioid adenocarcinoma of the rectovaginal septum: A case report.
Qingling MU ; Chun WANG ; Hongyun LIU ; Youzheng XU ; Shaohong LUAN ; Baoguo XIA
Journal of Central South University(Medical Sciences) 2023;48(6):941-946
Primary endometrioid adenocarcinoma of the rectovaginal septum is rare. Its pathogenesis is not clear and there is no standard treatment. One patient with endometrioid adenocarcinoma of the rectovaginal septum arising from deep infiltrative endometriosis was admitted to Qingdao Municipal Hospital. The patient presented with incessant menstruation and abdominal distension. She had bilateral ovarian endometriotic cystectomy 6 years ago. Imaging findings suggested a pelvic mass which might invade the rectovaginal septum. Pathological results of primary surgery confirmed endometrioid carcinoma of the pelvic mass arising from the rectovaginal septum. Then she had a comprehensive staged surgery. Postoperative chemotherapy was given 6 times. No recurrence or metastasis was found during the 2-year follow-up. The possibility of deep infiltrating endometriosis and its malignant transformation should be considered in the differential diagnosis of a new extragonadal pelvic lesion in a patient with a history of endometriosis, which would avoid misdiagnosis and missed diagnosis.
Female
;
Humans
;
Carcinoma, Endometrioid/surgery*
;
Endometriosis/surgery*
;
Rectum
;
Vagina
;
Cystectomy


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