1.Predicting late aortic complications after acute type A dissection surgery with volumetric measurements in a Singapore cohort.
Jasmine GE ; Vinay Bahadur PANDAY ; Siew-Pang CHAN ; Bernard WEE ; Julian Chi Leung WONG ; Leok Kheng Kristine TEOH ; Moe Thu SAN ; Carlos A MESTRES ; Theodoros KOFIDIS ; Vitaly A SOROKIN
Singapore medical journal 2025;66(9):469-475
INTRODUCTION:
This study was conducted to evaluate the efficacy of postoperative computed tomography (CT) measurements of aortic lumen volumes in predicting aortic-related complications following acute type A aortic dissection (ATAAD) repair.
METHODS:
We conducted a single-institution retrospective aortic volumetric analysis of patients after ascending aorta replacement performed during 2001-2015. The volumetric measurements of total lumen (total-L), true lumen (TL), false lumen (FL), as well as the TL:FL ratio from the first and second postoperative computer angiograms were obtained. A generalised structural equation model was created to analyse the predictive utility of TL:FL ratio.
RESULTS:
One hundred and twenty-five patients underwent surgical intervention, of whom 97 patients were eventually discharged and analysed for postoperative complications. A total of 19 patients were included in the final analysis. Patients with late postoperative aortic complications had a significantly higher FL volume and total-L volume on the first (FL volume P = 0.041, total-L volume P = 0.05) and second (FL volume P = 0.01, total-L volume P = 0.007) postoperative scans. The odds of having aortic complications were raised by 1% with a 1 cm 3 increase in total-L volume and by 2% with a 1 cm 3 increase in FL volume. The TL:FL ratio was significantly lower in patients who developed complications.
CONCLUSION
Postoperative CT volumetric measurements in patients who developed complications are characterised by a significant increase in the FL volume and total-L volume from the first postoperative scans. Patients with disproportionately expanded FL presenting with TL:FL ratios less than 1 were associated with aortic complications. Hence, the TL:FL ratio may be a reliable and useful parameter to monitor postoperative disease progression and to evaluate the risk of late complications in ATAAD patients.
Humans
;
Male
;
Female
;
Retrospective Studies
;
Singapore
;
Aortic Dissection/diagnostic imaging*
;
Middle Aged
;
Postoperative Complications/diagnostic imaging*
;
Aged
;
Tomography, X-Ray Computed
;
Aortic Aneurysm/diagnostic imaging*
;
Aorta/surgery*
;
Adult
;
Treatment Outcome
;
Computed Tomography Angiography
2.Case of oculomotor nerve palsy after the surgery of cranial-orbital communicating tumor.
Cangsong ZHAO ; Zhongyu TANG ; Tao WANG ; Haiyan WANG
Chinese Acupuncture & Moxibustion 2025;45(4):548-550
The paper reports acupuncture treatment for one case of oculomotor nerve palsy after cranial-orbital communicating tumor surgery. The acupoint prescription was composed of the local acupoints of the eyes (Yansanzhen, Tijian, Cuanzhu [BL2], Yuyao [EX-HN4] and Sizhukong [TE23]), the acupoints on the head, face and neck (Yangbai [GB14], Sibai [ST2] and Fengchi [GB20]), Guanyuan (CV4) on the abdomen, and those on the four limbs (Hegu [LI4], Zusanli [ST36], Shenmai [BL62] and Zhaohai [KI6]). The point-to-point needling technique with the eyelid lifted was operated at Tijian, Cuanzhu (BL2), Yuyao (EX-HN4), and Sizhukong (TE23). Warm needling with moxa cone placed on the needle handle was operated at Guanyuan (CV4) and Zusanli (ST36), and the usual needling technique was delivered at the rest acupoints. The treatment was given once daily, discontinued for 1 day after every 6 treatments. One course of treatment was composed of 7 days, and 6 courses were required. After treatment completion, the upper eyelids were basically symmetrical and the bilateral eye cracks were equal, the double vision appeared occasionally. No recurrence and no aggravation were reported in 1 month of follow up visit.
Humans
;
Acupuncture Points
;
Acupuncture Therapy
;
Oculomotor Nerve Diseases/etiology*
;
Orbital Neoplasms/surgery*
;
Postoperative Complications/etiology*
3.The efficacy and safety of radiofrequency ablation in papillary thyroid carcinoma: A systematic review and meta-analysis.
Wei Shuen Clarissa CHEONG ; Xin Yi Joy AU ; Ming Yann LIM ; Ernest Weizhong FU ; Hao LI ; Uei PUA ; Yong Quan Alvin SOON ; Yijin Jereme GAN
Annals of the Academy of Medicine, Singapore 2025;54(3):170-177
INTRODUCTION:
Radiofrequency ablation (RFA) avoids the complications of general anaesthesia, reduces length of hospitalisation and reduces morbidity from surgery. As such, it is a strong alternative treatment for patients with comorbidities who are not surgical candidates. However, to our knowledge, there have only been 1 systematic review and 3 combined systematic review and meta-analyses on this topic to date. This systematic review and meta-analysis seeks to evaluate the efficacy and safety of RFA in the treatment of papillary thyroid carcinoma (PTC) with longer follow-up durations.
METHOD:
PubMed, Embase and Cochrane databases were searched for relevant studies published from 1990 to 2021; 13 studies with a total of 1366 patients were included. The Preferred Reporting Items for Systematic reviews and Meta-Analyses guidelines and Sandelowski et al.'s approach1 to "negotiated consensual validation" were used to achieve consensus on the final list of articles to be included. All authors then assessed each study using a rating scheme modified from the Oxford Centre for Evidence-Based Medicine.
RESULTS:
Pooled volume reduction rates (VRRs) from 1 to 48 months after RFA, complete disappearance rates (CDR) and complications were assessed. Pooled mean VRRs were 96.59 (95% confidence interval [CI] 91.05-102.13, I2=0%) at 12 months2-6 and 99.31 (95% CI 93.74-104.88, I2=not applicable) at 48 months.2,5 Five studies showed an eventual CDR of 100%.2,4,7-9 No life-threatening complications were recorded. The most common complications included pain, transient voice hoarseness, fever and less commonly, first-degree burn.
CONCLUSION
RFA may be an effective and safe alternative to treating PTC. Larger clinical trials with longer follow-up are needed to further evaluate the effectiveness of RFA in treating PTC.
Humans
;
Radiofrequency Ablation/methods*
;
Thyroid Cancer, Papillary/surgery*
;
Thyroid Neoplasms/surgery*
;
Treatment Outcome
;
Postoperative Complications/etiology*
5.Guideline for prevention and treatment of common complications in older patients undergoing lumbar spinal fusion (2025 edition).
Chinese Journal of Surgery 2025;63(9):771-778
With the aging of the population in China, lumbar degenerative diseases among the older patients have drawn growing attention. Lumbar fusion is an important surgical treatment for degenerative diseases of the lumbar spine, which mainly achieves bony fusion between adjacent vertebrae through methods such as bone grafting and internal fixation. Due to the unique physiological and pathological characteristics of the older patients, it often leads to a higher risk of complications associated with lumbar fusion, which affects the patient's prognosis. However, there is still a lack of standards for the prevention and treatment of some common complications associated with lumbar fusion surgery in the older patients. The Chinese Medical Doctor Association Committee of Neural Restoration took the lead in establishing a guideline development group, followed the principles and methods of guideline development, and produced "Guideline for prevention and treatment of common complications in older patients undergoing lumbar spinal fusion(2025 edition)", covering ten types of common complications associated with lumbar fusion in the older patients with 20 recommendations for clinical practice reference.
Humans
;
Spinal Fusion/adverse effects*
;
Lumbar Vertebrae/surgery*
;
Postoperative Complications/therapy*
;
Aged
;
Spinal Diseases/surgery*
6.Development and validation of a predictive model for acute respiratory distress syndrome in geriatric patients following gastrointestinal perforation surgery.
Ze ZHANG ; You FU ; Jing YUAN ; Quansheng DU
Chinese Critical Care Medicine 2025;37(8):749-754
OBJECTIVE:
To identify the risk factors for acute respiratory distress syndrome (ARDS) in geriatric patients following gastrointestinal perforation surgery, and constructed a model to validate its predictive value.
METHODS:
A retrospective analysis was conducted. The clinical data of geriatric patients (aged ≥ 60 years) after gastrointestinal perforation surgery admitted to the intensive care unit (ICU) of Hebei General Hospital from October 2017 to October 2024 were enrolled. Two groups were divided according to whether ARDS occurred postoperatively, and the differences in each index between the groups were compared. Lasso regression and multifactorial Logistic regression analyses were used to identify independent risk factors for the development of ARDS, and a prediction model was constructed based on these, which was presented using a nomogram. The receiver operator characteristic curve (ROC curve), calibration curve, and decision curve analysis (DCA) were plotted to evaluate the discrimination, accuracy, and clinical practicability of the model.
RESULTS:
A total of 155 geriatric patients following gastrointestinal perforation surgery were ultimately included in the analysis, among whom 43 developed ARDS, with an incidence rate of 27.7%. There were significantly differences in age, body mass index (BMI), acute kidney injury comorbidity, heart rate, onset time, the duration of surgery, the site of perforation, seroperitoneum, amount of bleeding, shock comorbidity, central venous pressure (CVP), C-reactive protein, and albumin between ARDS and non-ARDS groups. Lasso regression identified nine significant predictors: age, BMI, acute kidney injury comorbidity, onset time, seroperitoneum, shock comorbidity, CVP, hemoglobin, and albumin. Multivariate Logistic regression analysis identified BMI [odds ratio (OR) = 1.310, P < 0.001], hemoglobin (OR = 1.019, P = 0.045), seroperitoneum (OR = 1.001, P = 0.017), and albumin (OR = 0.871, P < 0.001) as independent risk factors for the occurrence of ARDS. A prediction model was constructed based on the above four independent risk factors, and the ROC curve showed that the area under the curve (AUC) of the model for predicting the occurrence of ARDS was 0.885 [95% confidence interval (95%CI) was 0.824-0.946], and internal validation was performed using bootstrap resampling (Bootstrap 500 times), which showed that the AUC value of the model was 0.886 (95%CI was 0.883-0.889). Calibration curves revealed excellent concordance between observed outcomes and model predictions. DCA indicated a high net benefit value for the model, which has good clinical utility.
CONCLUSIONS
BMI, hemoglobin, seroperitoneum, and albumin were identified as independent risk factors for ARDS in geriatric patients following gastrointestinal perforation surgery. The prediction model constructed using these four indicators facilitates early identification of high-risk individuals by clinicians.
Humans
;
Respiratory Distress Syndrome/etiology*
;
Retrospective Studies
;
Aged
;
Risk Factors
;
Logistic Models
;
Postoperative Complications
;
Intestinal Perforation/surgery*
;
Male
;
ROC Curve
;
Female
;
Middle Aged
;
Intensive Care Units
;
Nomograms
7.Conservative treatment of pathological fracture after multiple odontogenic keratocyst surgery: a case report and literature analysis.
Chen XU ; Hongguang CHANG ; Qiang SHAO ; Yonghai SONG
West China Journal of Stomatology 2025;43(1):144-150
Pathological fractures after jaw cyst surgery are rare clinically but are a serious complication. Once a pathological fracture occurs, treatment time and economic costs increase, and doctors face difficulty in handling it. This article reports a case of a patient with mandibular pathological fractures after multiple odontogenic keratocyst surgery of the jaw. Mandibular lesions were located in the bilateral mandibular angles and had macrocystic changes. We adopted a conservative treatment plan, and the treatment effect was good. We also discussed and analyzed relevant literature to provide a reference for clinicians.
Humans
;
Odontogenic Cysts/surgery*
;
Conservative Treatment
;
Postoperative Complications/therapy*
;
Mandibular Fractures/etiology*
;
Fractures, Spontaneous/etiology*
;
Male
;
Female
8.Management of accidental tooth root displacement into the mandibular canal during tooth extraction.
West China Journal of Stomatology 2025;43(6):789-796
The accidental displacement of tooth roots into the mandibular canal is a serious complication during tooth extractions in oral and maxillofacial surgery, often resulting in direct damage to the structural and functional integrity of the inferior alveolar neurovascular bundle (IANB). This article reviews the anatomical features of the mandibular canal, the IANB, and adjacent tooth roots; identifies high-risk factors and anatomically vulnerable sites for root displacement; and outlines the clinical manifestations and radiographic characteristics of intraoperative root intrusion into the mandibular canal. Furthermore, management principles, surgical approaches and techniques, inferior alveolar nerve injury treatment, and prognostic considerations are discussed. The aim of this review is to provide a comprehensive clinical reference for improving surgical outcomes, and reducing postoperative complications.
Humans
;
Tooth Extraction/adverse effects*
;
Mandible/surgery*
;
Tooth Root
;
Mandibular Nerve/anatomy & histology*
;
Postoperative Complications/prevention & control*
;
Intraoperative Complications
;
Mandibular Nerve Injuries/etiology*
9.Risk Factors for Prolonged Postoperative Length of Stay After Hip Fracture Surgery in Very Elderly Patients.
Bo-Wen XU ; Wei-Yun CHEN ; Chen SUN ; Ling LAN ; Lu-Lu MA ; Li-Jian PEI
Chinese Medical Sciences Journal 2025;40(2):111-119
OBJECTIVES:
To identify risk factors contributing to prolonged postoperative length of stay (LOS) in very elderly patients following hip fracture surgery, with a focus on postoperative complications and the impact of different anesthesia approaches.
METHODS:
This retrospective single-center cohort study enrolled patients aged 90 years or older who underwent hip fracture surgery at Peking Union Medical College Hospital between January 31, 2013 and December 31, 2023. Relevant perioperative data were collected. The primary outcome was postoperative LOS, and the study cohort was divided into two groups: postoperative LOS ≤ 7 days and LOS > 7 days. Logistic regression was performed to identify factors related to prolonged postoperative LOS.
RESULTS:
A total of 155 patients were included. The average age was 92.7 ± 2.6 years. There were 73 (47%) patients with postoperative LOS > 7 days. Postoperative pneumonia was the only factor associated with a prolonged postoperative LOS (OR = 2.12, 95% CI [1.09, 4.16], P = 0.028). Neither the type of anesthesia (regional vs. general anesthesia, OR = 1.00, 95% CI [0.53, 1.90], P = 0.993) nor the method of airway management (laryngeal mask ventilation vs. spontaneous breathing, OR = 1.46, 95% CI [0.58, 3.76], P = 0.424; endotracheal intubation vs. spontaneous breathing, OR = 0.82, 95% CI [0.39, 1.69], P = 0.592) showed a significant association with a prolonged postoperative LOS. Preoperative chronic obstructive pulmonary disease (OR = 2.78, 95% CI [1.05, 7.65], P = 0.040) and preoperative neutrophil count (OR = 1.13, 95% CI [1.01, 1.26], P = 0.029) were both significantly associated with the occurrence of postoperative pneumonia, while anesthesia type and airway management method were not.
CONCLUSIONS
Postoperative pneumonia was associated with prolonged postoperative LOS in very elderly patients undergoing hip fracture surgery, whereas anesthesia types and airway management methods show no association with prolonged postoperative LOS or postoperative pneumonia. Preoperative comorbidities, especially respiratory conditions and systemic inflammation, potentially play a substantial role in postoperative recovery.
Humans
;
Hip Fractures/surgery*
;
Aged, 80 and over
;
Risk Factors
;
Length of Stay
;
Female
;
Male
;
Retrospective Studies
;
Postoperative Complications/etiology*
10.Effectiveness analysis of 5G remote robotic surgery in pelvic fracture treatment.
Yonghong DAI ; Kuangyang YANG ; Yanhui ZENG ; Wei HAN ; Junqiang WANG
Chinese Journal of Reparative and Reconstructive Surgery 2025;39(4):391-398
OBJECTIVE:
To investigate the effectiveness of 5G remote robotic surgery in the treatment of pelvic fractures.
METHODS:
A retrospective analysis was conducted on the clinical data of 160 patients with pelvic fractures admitted between July 2023 and June 2024 who met the selection criteria. Among these patients, 80 underwent internal fixation surgery with the assistance of 5G remote robotic surgery (5G group), while 80 received local robotic surgical assistance (control group). Baseline characteristics, including gender, age, body mass index, disease duration, cause of injury, and fracture classification, were compared between the two groups, and no significant difference was found ( P>0.05). The incision length, operation time, intraoperative blood loss, hospital stay, accuracy of screw placement, maximum residual displacement postoperatively, quality of fracture reduction, incidence of complications, Majeed pelvic function score and classification at last follow-up were recorded and compared between the two groups.
RESULTS:
In the 5G group, 180 screws were implanted during surgery, while 213 screws were implanted in the control group. The 5G group demonstrated significantly reduced intraoperative blood loss and shorter incision length compared to the control group ( P<0.05). No significant difference was observed between the two groups in terms of operation time or hospital stay ( P>0.05). Radiographic evaluation revealed excellent and good reduction rates of 98.8% (79/80) in the 5G group and 97.5% (78/80) in the control group, while excellent and good screw placement accuracy rates were 98.3% (177/180) in the 5G group and 95.8% (204/213) in the control group. No significant difference was found between the two groups in maximum residual displacement, reduction quality, or screw placement accuracy ( P>0.05). All patients were followed up 7-16 months (mean, 11.3 months), with no significant difference in follow-up duration between the groups ( P>0.05). No perioperative or follow-up complication, such as wound infection, iatrogenic fractures, iatrogenic neurovascular injury, screw loosening or breakage, or nonunion, were observed in either group. The control group exhibited a worse degree of gait alteration compared to the 5G group ( P<0.05), while no significant difference was found in incidences of squatting limitation or persistent pain ( P>0.05). At last follow-up, no significant difference was observed between the groups in Majeed pelvic function scores or grading ( P>0.05).
CONCLUSION
Compared with the local surgery group, 5G remote robotic surgery supported by remote expert technical guidance demonstrated smaller incision lengths, less intraoperative blood loss, and fewer postoperative complications, and was shown to be a precise, minimally invasive, safe, and reliable surgical method.
Humans
;
Robotic Surgical Procedures/instrumentation*
;
Pelvic Bones/surgery*
;
Male
;
Retrospective Studies
;
Fracture Fixation, Internal/instrumentation*
;
Female
;
Fractures, Bone/surgery*
;
Middle Aged
;
Bone Screws
;
Adult
;
Operative Time
;
Treatment Outcome
;
Blood Loss, Surgical
;
Length of Stay
;
Postoperative Complications/epidemiology*
;
Aged
;
Young Adult

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