1.Development of an abdominal acupoint localization system based on AI deep learning.
Mo ZHANG ; Yuming LI ; Zongming SHI
Chinese Acupuncture & Moxibustion 2025;45(3):391-396
This study aims to develop an abdominal acupoint localization system based on computer vision and convolutional neural networks (CNNs). To address the challenge of abdominal acupoint localization, a multi-task CNNs architecture was constructed and trained to locate the Shenque (CV8) and human body boundaries. Based on the identified Shenque (CV8), the system further deduces key characteristics of four acupoints: Shangwan (CV13), Qugu (CV2), and bilateral Daheng (SP15). An affine transformation matrix is applied to accurately map image coordinates to an acupoint template space, achieving precise localization of abdominal acupoints. Testing has verified that this system can accurately identify and locate abdominal acupoints in images. The development of this localization system provides technical support for TCM remote education, diagnostic assistance, and advanced TCM equipment, such as intelligent acupuncture robots, facilitating the standardization and intelligent advancement of acupuncture.
Acupuncture Points
;
Humans
;
Deep Learning
;
Abdomen/diagnostic imaging*
;
Neural Networks, Computer
;
Acupuncture Therapy
;
Image Processing, Computer-Assisted
2.Construction of an artificial intelligence-assisted system for auxiliary detection of auricular point features based on the YOLO neural network.
Ganhong WANG ; Zihao ZHANG ; Kaijian XIA ; Yanting ZHOU ; Meijuan XI ; Jian CHEN
Chinese Acupuncture & Moxibustion 2025;45(4):413-420
OBJECTIVE:
To develop an artificial intelligence-assisted system for the automatic detection of the features of common 21 auricular points based on the YOLOv8 neural network.
METHODS:
A total of 660 human auricular images from three research centers were collected from June 2019 to February 2024. The rectangle boxes and features of images were annotated using the LabelMe5.3.1 tool and converted them into a format compatible with the YOLO model. Using these data, transfer learning and fine-tuning training were conducted on different scales of pretrained YOLO neural network models. The model's performance was evaluated on validation and test sets, including the mean average precision (mAP) at various thresholds, recall rate (recall), frames per second (FPS) and confusion matrices. Finally, the model was deployed on a local computer, and the real-time detection of human auricular images was conducted using a camera.
RESULTS:
Five different versions of the YOLOv8 key-point detection model were developed, including YOLOv8n, YOLOv8s, YOLOv8m, YOLOv8l, and YOLOv8x. On the validation set, YOLOv8n showed the best performance in terms of speed (225.736 frames per second) and precision (0.998). On the external test set, YOLOv8n achieved the accuracy of 0.991, the sensitivity of 1.0, and the F1 score of 0.995. The localization performance of auricular point features showed the average accuracy of 0.990, the precision of 0.995, and the recall of 0.997 under 50% intersection ration (mAP50).
CONCLUSION
The key-point detection model of 21 common auricular points based on YOLOv8n exhibits the excellent predictive performance, which is capable of rapidly and automatically locating and classifying auricular points.
Humans
;
Neural Networks, Computer
;
Artificial Intelligence
;
Acupuncture Points
3.Research status of automatic localization of acupoint based on deep learning.
Yuge DONG ; Chengbin WANG ; Weigang MA ; Weifang GAO ; Yuzi TANG ; Yonglong ZHANG ; Jiwen QIU ; Haiyan REN ; Zhongzheng LI ; Tianyi ZHAO ; Zhongxi LV ; Xingfang PAN
Chinese Acupuncture & Moxibustion 2025;45(5):586-592
This paper reviews the published articles of recent years on the application of deep learning methods in automatic localization of acupoint, and summarizes it from 3 key links, i.e. the dataset construction, the neural network model design, and the accuracy evaluation of acupoint localization. The significant progress has been obtained in the field of deep learning for acupoint localization, but the scale of acupoint detection needs to be expanded and the precision, the generalization ability, and the real-time performance of the model be advanced. The future research should focus on the support of standardized datasets, and the integration of 3D modeling and multimodal data fusion, so as to increase the accuracy and strengthen the personalization of acupoint localization.
Deep Learning
;
Acupuncture Points
;
Humans
;
Neural Networks, Computer
4.Role of artificial intelligence in medical image analysis.
Lu WANG ; Shimin ZHANG ; Nan XU ; Qianqian HE ; Yuming ZHU ; Zhihui CHANG ; Yanan WU ; Huihan WANG ; Shouliang QI ; Lina ZHANG ; Yu SHI ; Xiujuan QU ; Xin ZHOU ; Jiangdian SONG
Chinese Medical Journal 2025;138(22):2879-2894
With the emergence of deep learning techniques based on convolutional neural networks, artificial intelligence (AI) has driven transformative developments in the field of medical image analysis. Recently, large language models (LLMs) such as ChatGPT have also started to achieve distinction in this domain. Increasing research shows the undeniable role of AI in reshaping various aspects of medical image analysis, including processes such as image enhancement, segmentation, detection in image preprocessing, and postprocessing related to medical diagnosis and prognosis in clinical settings. However, despite the significant progress in AI research, studies investigating the recent advances in AI technology in the aforementioned aspects, the changes in research hotspot trajectories, and the performance of studies in addressing key clinical challenges in this field are limited. This article provides an overview of recent advances in AI for medical image analysis and discusses the methodological profiles, advantages, disadvantages, and future trends of AI technologies.
Artificial Intelligence
;
Humans
;
Image Processing, Computer-Assisted/methods*
;
Neural Networks, Computer
;
Deep Learning
;
Diagnostic Imaging/methods*
5.Optimization of extraction process for Shenxiong Huanglian Jiedu Granules based on AHP-CRITIC hybrid weighting method, grey correlation analysis, and BP-ANN.
Zi-An LI ; De-Wen LIU ; Xin-Jian LI ; Bing-Yu WU ; Qun LAN ; Meng-Jia GUO ; Jia-Hui SUN ; Nan-Yang LIU ; Hui PEI ; Hao LI ; Hong YI ; Jin-Yu WANG ; Liang-Mian CHEN
China Journal of Chinese Materia Medica 2025;50(10):2674-2683
By employing the analytic hierarchy process(AHP), the CRITIC method(a weight determination method based on indicator correlations), and the AHP-CRITIC hybrid weighting method, the weight coefficients of evaluation indicators were determined, followed by a comprehensive score comparison. The grey correlation analysis was then performed to analyze the results calculated using the hybrid weighting method. Subsequently, a backpropagation-artificial neural network(BP-ANN) model was constructed to predict the extraction process parameters and optimize the extraction process for Shenxiong Huanglian Jiedu Granules(SHJG). In the extraction process, an L_9(3~4) orthogonal experiment was designed to optimize three factors at three levels, including extraction frequency, water addition amount, and extraction time. The evaluation indicators included geniposide, berberine, ginsenoside Rg_1 + Re, ginsenoside Rb_1, ferulic acid, and extract yield. Finally, the optimal extraction results obtained by the orthogonal experiment, grey correlation analysis, and BP-ANN method were compared, and validation experiments were conducted. The results showed that the optimal extraction process involved two rounds of aqueous extraction, each lasting one hour; the first extraction used ten times the amount of added water, while the second extraction used eight times the amount. In the validation experiments, the average content of each indicator component was higher than the average content obtained in the orthogonal experiment, with a higher comprehensive score. The optimized extraction process parameters were reliable and stable, making them suitable for subsequent preparation process research.
Drugs, Chinese Herbal/analysis*
;
Neural Networks, Computer
6.The joint analysis of heart health and mental health based on continual learning.
Hongxiang GAO ; Zhipeng CAI ; Jianqing LI ; Chengyu LIU
Journal of Biomedical Engineering 2025;42(1):1-8
Cardiovascular diseases and psychological disorders represent two major threats to human physical and mental health. Research on electrocardiogram (ECG) signals offers valuable opportunities to address these issues. However, existing methods are constrained by limitations in understanding ECG features and transferring knowledge across tasks. To address these challenges, this study developed a multi-resolution feature encoding network based on residual networks, which effectively extracted local morphological features and global rhythm features of ECG signals, thereby enhancing feature representation. Furthermore, a model compression-based continual learning method was proposed, enabling the structured transfer of knowledge from simpler tasks to more complex ones, resulting in improved performance in downstream tasks. The multi-resolution learning model demonstrated superior or comparable performance to state-of-the-art algorithms across five datasets, including tasks such as ECG QRS complex detection, arrhythmia classification, and emotion classification. The continual learning method achieved significant improvements over conventional training approaches in cross-domain, cross-task, and incremental data scenarios. These results highlight the potential of the proposed method for effective cross-task knowledge transfer in ECG analysis and offer a new perspective for multi-task learning using ECG signals.
Humans
;
Electrocardiography/methods*
;
Mental Health
;
Algorithms
;
Signal Processing, Computer-Assisted
;
Machine Learning
;
Arrhythmias, Cardiac/diagnosis*
;
Cardiovascular Diseases
;
Neural Networks, Computer
;
Mental Disorders
7.Research on motor imagery recognition based on feature fusion and transfer adaptive boosting.
Yuxin ZHANG ; Chenrui ZHANG ; Shihao SUN ; Guizhi XU
Journal of Biomedical Engineering 2025;42(1):9-16
This paper proposes a motor imagery recognition algorithm based on feature fusion and transfer adaptive boosting (TrAdaboost) to address the issue of low accuracy in motor imagery (MI) recognition across subjects, thereby increasing the reliability of MI-based brain-computer interfaces (BCI) for cross-individual use. Using the autoregressive model, power spectral density and discrete wavelet transform, time-frequency domain features of MI can be obtained, while the filter bank common spatial pattern is used to extract spatial domain features, and multi-scale dispersion entropy is employed to extract nonlinear features. The IV-2a dataset from the 4 th International BCI Competition was used for the binary classification task, with the pattern recognition model constructed by combining the improved TrAdaboost integrated learning algorithm with support vector machine (SVM), k nearest neighbor (KNN), and mind evolutionary algorithm-based back propagation (MEA-BP) neural network. The results show that the SVM-based TrAdaboost integrated learning algorithm has the best performance when 30% of the target domain instance data is migrated, with an average classification accuracy of 86.17%, a Kappa value of 0.723 3, and an AUC value of 0.849 8. These results suggest that the algorithm can be used to recognize MI signals across individuals, providing a new way to improve the generalization capability of BCI recognition models.
Brain-Computer Interfaces
;
Humans
;
Support Vector Machine
;
Algorithms
;
Neural Networks, Computer
;
Imagination/physiology*
;
Pattern Recognition, Automated/methods*
;
Electroencephalography
;
Wavelet Analysis
8.Research on arrhythmia classification algorithm based on adaptive multi-feature fusion network.
Mengmeng HUANG ; Mingfeng JIANG ; Yang LI ; Xiaoyu HE ; Zefeng WANG ; Yongquan WU ; Wei KE
Journal of Biomedical Engineering 2025;42(1):49-56
Deep learning method can be used to automatically analyze electrocardiogram (ECG) data and rapidly implement arrhythmia classification, which provides significant clinical value for the early screening of arrhythmias. How to select arrhythmia features effectively under limited abnormal sample supervision is an urgent issue to address. This paper proposed an arrhythmia classification algorithm based on an adaptive multi-feature fusion network. The algorithm extracted RR interval features from ECG signals, employed one-dimensional convolutional neural network (1D-CNN) to extract time-domain deep features, employed Mel frequency cepstral coefficients (MFCC) and two-dimensional convolutional neural network (2D-CNN) to extract frequency-domain deep features. The features were fused using adaptive weighting strategy for arrhythmia classification. The paper used the arrhythmia database jointly developed by the Massachusetts Institute of Technology and Beth Israel Hospital (MIT-BIH) and evaluated the algorithm under the inter-patient paradigm. Experimental results demonstrated that the proposed algorithm achieved an average precision of 75.2%, an average recall of 70.1% and an average F 1-score of 71.3%, demonstrating high classification accuracy and being able to provide algorithmic support for arrhythmia classification in wearable devices.
Humans
;
Arrhythmias, Cardiac/diagnosis*
;
Algorithms
;
Electrocardiography/methods*
;
Neural Networks, Computer
;
Signal Processing, Computer-Assisted
;
Deep Learning
;
Classification Algorithms
9.Research on intelligent fetal heart monitoring model based on deep active learning.
Bin QUAN ; Yajing HUANG ; Yanfang LI ; Qinqun CHEN ; Honglai ZHANG ; Li LI ; Guiqing LIU ; Hang WEI
Journal of Biomedical Engineering 2025;42(1):57-64
Cardiotocography (CTG) is a non-invasive and important tool for diagnosing fetal distress during pregnancy. To meet the needs of intelligent fetal heart monitoring based on deep learning, this paper proposes a TWD-MOAL deep active learning algorithm based on the three-way decision (TWD) theory and multi-objective optimization Active Learning (MOAL). During the training process of a convolutional neural network (CNN) classification model, the algorithm incorporates the TWD theory to select high-confidence samples as pseudo-labeled samples in a fine-grained batch processing mode, meanwhile low-confidence samples annotated by obstetrics experts were also considered. The TWD-MOAL algorithm proposed in this paper was validated on a dataset of 16 355 prenatal CTG records collected by our group. Experimental results showed that the algorithm proposed in this paper achieved an accuracy of 80.63% using only 40% of the labeled samples, and in terms of various indicators, it performed better than the existing active learning algorithms under other frameworks. The study has shown that the intelligent fetal heart monitoring model based on TWD-MOAL proposed in this paper is reasonable and feasible. The algorithm significantly reduces the time and cost of labeling by obstetric experts and effectively solves the problem of data imbalance in CTG signal data in clinic, which is of great significance for assisting obstetrician in interpretations CTG signals and realizing intelligence fetal monitoring.
Humans
;
Pregnancy
;
Female
;
Cardiotocography/methods*
;
Deep Learning
;
Neural Networks, Computer
;
Algorithms
;
Fetal Monitoring/methods*
;
Heart Rate, Fetal
;
Fetal Distress/diagnosis*
;
Fetal Heart/physiology*
10.Neural network for auditory speech enhancement featuring feedback-driven attention and lateral inhibition.
Yudong CAI ; Xue LIU ; Xiang LIAO ; Yi ZHOU
Journal of Biomedical Engineering 2025;42(1):82-89
The processing mechanism of the human brain for speech information is a significant source of inspiration for the study of speech enhancement technology. Attention and lateral inhibition are key mechanisms in auditory information processing that can selectively enhance specific information. Building on this, the study introduces a dual-branch U-Net that integrates lateral inhibition and feedback-driven attention mechanisms. Noisy speech signals input into the first branch of the U-Net led to the selective feedback of time-frequency units with high confidence. The generated activation layer gradients, in conjunction with the lateral inhibition mechanism, were utilized to calculate attention maps. These maps were then concatenated to the second branch of the U-Net, directing the network's focus and achieving selective enhancement of auditory speech signals. The evaluation of the speech enhancement effect was conducted by utilising five metrics, including perceptual evaluation of speech quality. This method was compared horizontally with five other methods: Wiener, SEGAN, PHASEN, Demucs and GRN. The experimental results demonstrated that the proposed method improved speech signal enhancement capabilities in various noise scenarios by 18% to 21% compared to the baseline network across multiple performance metrics. This improvement was particularly notable in low signal-to-noise ratio conditions, where the proposed method exhibited a significant performance advantage over other methods. The speech enhancement technique based on lateral inhibition and feedback-driven attention mechanisms holds significant potential in auditory speech enhancement, making it suitable for clinical practices related to artificial cochleae and hearing aids.
Humans
;
Attention/physiology*
;
Speech Perception/physiology*
;
Neural Networks, Computer
;
Speech
;
Noise
;
Feedback

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