OBJECTIVES

The current study aimed to evaluate the impact of an interprofessional simulation-based training program on providers' perception, knowledge, and confidence in proning of pregnant patients with Acute Respiratory Distress Syndrome due to COVID -19 or other causes.

A total of 124 healthcare workers who took part in the management of patients in COVID wards and ICUs participated in the study. The simulation workshop was conducted on May 2022 and the participants were divided into interprofessional teams. Standardized patients and mannequins were used to simulate patients with ARDS. Standardized checklists for proning were used. The participants were debriefed after. The participants completed pre- and post-simulation questionnaires.

After the simulation workshop, the participants’ perception on the benefit of prone position in the ventilation of patients with ARDS, level of confidence in handling proning of pregnant patients, comfort in speaking to patient and next of kin regarding prone ventilation, and knowledge on proning significantly improved. Subgroup analysis
showed statistically significant improvements in knowledge scores among registered nurses, resident physicians, and participants with varying degrees of experience managing COVID-19 patients and proning pregnant patients. Majority of participants deemed it was easy to turn patients in the prone position using the supportive pillow as well as expressed confidence in doing the procedure.

Interprofessional simulation-based training of healthcare workers improved providers' knowledge and confidence in proning pregnant patients. Simulation based training also improved the comfort of the healthcare professional in advising the patient and next of kin on the benefits of proning.
Human ; World Health Organization ; Respiratory Insufficiency ; Handling (psychology) ; Occupational Groups ; Knowledge

INRODUCTION

The growing misuse of antibiotics and the escalating threat of antibiotic resistance in the Philippines pose significant public health concerns. While various Knowledge, Attitudes and Practices (KAP) questionnaires on personal antibiotic use have been employed in local studies, none have been fully validated and a standardized, culturally appropriate tool remains lacking.

This study aims to develop a Filipino-translated and culturally adapted KAP questionnaire on personal antibiotic use (KAPQ-PAU-FIL) and evaluate its validity and reliability.

The research consisted of two phases. The first phase is the translation and cross-cultural adaptation of the original questionnaire in collaboration with the UST Sentro sa Salin at Araling Salin. The second phase is the validity and reliability testing of the KAPQ-PAU-FIL using a sample of 176 Filipino adults. This included assessment of its face validity, content validity, construct validity, internal consistency, test-retest reliability and equivalent forms reliability.

Most items were translated without difficulty, though four items were modified to better fit the linguistic and cultural context. The KAPQ-PAU-FIL demonstrates strong psychometric properties, with face validity (SFVI/Ave = 0.99), content validity (SCVI/Ave = 0.99), construct validity (CFI = 0.92, RMSEA = 0.06, SRMR = 0.04; FL = 0.60-0.85; ITC = 0.58-0.71), test-retest reliability (ICC = 0.83), internal consistency (α = 0.929) and equivalent forms reliability (p>0.05; κ = 0.62-0.74).

The KAPQ-PAU-FIL is the first ever, Filipino-translated, culturally adapted questionnaire designed to assess KAPQ-PAU-FIL, demonstrating strong validity and reliability to support public health programs against antibiotic misuse.

BACKGROUND AND OBJECTIVES

Antimicrobial resistance (AMR) constitutes an escalating global public health menace, intensified by the excessive utilization of antibiotics in human healthcare and agriculture. In the Philippines, the extensive misuse of antimicrobials in food production, especially in chicken, swine, aquaculture, and agriculture exacerbate AMR, presenting considerable threats to public health. Since the transmission of AMR is closely linked to food safety, food handlers play a critical role in mitigating its spread. This study evaluates the knowledge, attitude, and practices (KAP) of food handlers in the Greater Manila Area concerning AMR and the utilization of antimicrobials.

This quasi-experimental study involved developing and implementing a customized training program based on pre-training KAP questionnaires, featuring specialized training materials for fruits and vegetables sellers, meat handlers, seafood vendors, and street food vendors. The training, conducted in partnership with government entities and industry specialists, emphasized AMR awareness, food safety rules, and optimal procedures for reducing AMR hazards.

The results showed statistically significant differences in pre- and post-intervention mean percentage scores in the participants’ knowledge, attitudes, and practices about food handling and AMR. There was also substantial improvement observed across all four occupational groups as post-test scores increased in comparison to their baseline scores.

This study underscores the pivotal role of food handlers in combating AMR and stresses the necessity for a training program that is focused on AMR education within food safety initiatives. The training program should be customized, for example, according to the length of experience of the food handler, to either provide basic food safety measures or to improve and upgrade the acquired baseline knowledge and skills related to food safety. This particular study showed the importance of providing food handlers with essential knowledge and skills on food safety and proper food handling to aid in the mitigation of AMR transmission.

BACKGROUND

Stroke is a leading cause of morbidity and mortality in the Philippines. Telestroke systems have been introduced to improve timely recognition and referral; however, their effectiveness depends on utilization at the community level.

To assess stroke and telestroke knowledge, attitudes, practices, and barriers among barangay health workers (BHWs), and to determine factors associated with telestroke utilization.

A cross-sectional study was conducted among 202 BHWs. Data were collected using a structured questionnaire assessing knowledge, attitudes, practices, and perceived barriers. Descriptive statistics were used to summarize responses. Associations between variables were analyzed using appropriate statistical tests, with significance set at p < 0.05.

Respondents had high stroke knowledge (75.5%, SD = 17.45) and telestroke knowledge (85.5%, SD = 18.82), as well as favorable attitudes (mean = 4.37). However, only 31.1% reported telestroke utilization. The most commonly reported barriers were lack of training (61.4%) and poor internet connectivity (15.8%). Telestroke familiarity was significantly associated with higher knowledge (p = 0.005) and more favorable attitudes (p = 0.001). Stroke-related training (p = 0.001) and years of experience (p = 0.001) were significantly associated with higher utilization.

Despite high knowledge and favorable attitudes, telestroke utilization among BHWs remains low. Training, familiarity, and infrastructure appear to play key roles in bridging the gap between knowledge and practice. Strengthening these factors may improve the effectiveness of community-based telestroke systems.

Introduction: Leptospirosis is a zoonotic disease transmitted through exposure to water or soil contaminated with the urine of infected animals, particularly rats. Despite ongoing prevention efforts, leptospirosis remains a public health concern in the Philippines, especially in flood-prone urban communities. This study assessed the knowledge, attitudes, and practices (KAP) regarding leptospirosis among residents of Barangay Doña Imelda, Quezon City, and examined the association of selected sociodemographic factors with KAP. Methods: A cross-sectional design was used with 345 residents of Barangay Doña Imelda. Data were collected using an adapted KAP questionnaire. Open-ended questions were used to probe the responses further. Statistical analyses included descriptive statistics and Spearman’s Rho correlation, Independent T-test, One-way and Welch ANOVA, and appropriate post hoc tests. Relationships among KAP domains were evaluated using Spearman’s rank correlation coefficient. Statistical significance was set at p < 0.05. Results: Respondents demonstrated high levels of knowledge (86.80%) and positive attitudes (90.91%) toward leptospirosis, but comparatively lower practice scores (69.25%). Knowledge scores differed significantly according to household size and civil status, while attitude and practice scores varied significantly across sex, educational attainment, and household income. Weak but significant positive correlations were observed between knowledge and attitude (rs = 0.126, p = 0.020), knowledge and practice (rs = 0.169, p = 0.002), and attitude and practice (rs = 0.170, p = 0.001). Conclusion Residents of Barangay Doña Imelda demonstrated adequate knowledge and positive attitudes toward leptospirosis; however, preventive practices remained suboptimal. Significant associations between KAP and selected sociodemographic factors were identified. Targeted health education, improved symptom recognition, and increased access to preventive resources may help strengthen leptospirosis prevention in high-risk urban communities.
Leptospirosis ; Knowledge ; Attitude ; Parks, Recreational ; Philippines

BACKGROUND

The Philippines has been significantly affected by the HIV epidemic in the Asia-Pacific region, with a notable increase in new cases over the past decade. Despite efforts to promote HIV testing, access to treatment, and awareness campaigns, progress has been slow, particularly among youths. Tangere, a market research application, conducted surveys during and after the COVID-19 pandemic to assess HIV knowledge among Filipinos.

This study aimed to evaluate changes in HIV awareness among young Filipinos during and after the COVID-19 pandemic using data collected via Tangere’s surveys. Specifically, it sought to analyze demographic characteristics, sources of HIV information, and knowledge regarding HIV transmission, prevention, and stigma.

Tangere collaborated with the investigators to develop a questionnaire assessing HIV knowledge among young Filipinos. Surveys were conducted during and after the COVID-19 pandemic, targeting subscribers aged 18-35 years, primarily from the National Capital Region and Luzon area. Data analysis involved calculating frequencies and percentages to summarize demographic characteristics and HIV knowledge. An Independent-Samples Proportions procedure was used to compare HIV knowledge during and after the pandemic.

The survey revealed that while respondents generally possessed reasonable knowledge about HIV, there were notable changes in the awareness during and after the pandemic. Social media and television were identified as primary sources of HIV information. Knowledge regarding HIV transmission and prevention increased postpandemic, particularly concerning preventive measures such as pre-exposure prophylaxis (PREP) and motherto-child transmission (MTCT). However, persistent misconceptions and stigma surrounding HIV remained, indicating the need for continued education and advocacy efforts.

The study underscores the importance of utilizing social media platforms for HIV awareness campaigns, especially among youths who are disproportionately affected by the epidemic. Despite improvements in knowledge, the Philippines has yet to achieve global HIV prevention goals. Continued efforts to enhance awareness, particularly regarding recent advancements in HIV prevention and treatment, are essential for curbing the epidemic and improving public health outcomes nationwide.

Biomanufacturing is an advanced manufacturing method that integrates biology, chemistry, and engineering. It utilizes renewable biomass and biological organisms as production media to scale up the production of target products through fermentation. Compared with petrochemical routes, biomanufacturing offers significant advantages in reducing CO₂ emissions, lowering energy consumption, and cutting costs. With the development of systems biology and synthetic biology and the accumulation of bioinformatics data, the integration of information technologies such as artificial intelligence, large models, and high-performance computing with biotechnology is propelling biomanufacturing into a data-driven era. This paper reviews the latest research progress on databases, knowledge bases, and large language models for biomanufacturing. It explores the development directions, challenges, and emerging technical methods in this field, aiming to provide guidance and inspiration for scientific research in related areas.
Biotechnology/methods* ; Knowledge Bases ; Synthetic Biology ; Databases, Factual ; Artificial Intelligence ; Systems Biology ; Computational Biology ; Fermentation

BACKGROUND

Skin cancer incidence has risen in recent decades, with excessive ultraviolet radiation exposure being a significant factor, especially among athletes involved in outdoor sports. This study examines differences in knowledge, attitudes, and practices (KAP) regarding sun exposure and protection between urban and rural college track and field athletes.

This cross-sectional study was conducted in the Philippines with 60 college track and field athletes selected through nonprobability convenience sampling. A questionnaire, adapted from two local studies, assessed KAP regarding sun exposure. The final questionnaire was then distributed via Google Forms. Pearson’s correlation assessed the relationships between KAP.

Urban and rural athletes lacked adequate knowledge about sun exposure and protection, though urban athletes had a slightly higher knowledge score. Urban athletes exhibited more desirable attitudes toward sun protection. Both the groups showed inadequate sun protection practices. Social media was the most common source of information.

This study found that while locality does not determine sun protection practices, urban athletes showed more positive attitudes. Greater knowledge was linked to better attitudes but did not always translate into improved practices. Addressing barriers that hinder the application of sun protection knowledge is essential to bridging this gap and promoting consistent sun safety behaviors, especially among athletes who engage in outdoor sports.

BACKGROUND

Human immunodeficiency virus infection and acquired immunodeficiency syndrome are significant public health concerns and social issues. Key players in efforts to stop HIV/AIDS as a public threat are healthcare personnel. Research has shown that negative attitudes of healthcare workers towards HIV can negatively influence their practices and these are associated with their level of knowledge about the disease.

This study aims to investigate the baseline knowledge, attitudes, and practices of healthcare workers towards HIV/AIDS and to determine the association between profession and level of knowledge, attitudes and practices among healthcare workers in a tertiary pediatric government hospital.

This study utilized an analytical cross-sectional research design. Data were collected through a written questionnaire administered to 213 healthcare personnel, who were selected via stratified random sampling from January to April 2024. Knowledge, attitude, and practice (KAP) scores were evaluated using Bloom’s cut-off points. Scores below 60% were classified as low level of knowledge, negative attitude, and poor practice. Scores from 60-79% were classified as moderate level of knowledge, neutral attitude and fair practice. Lastly, scores between 80-100% were classified as high level of knowledge, positive attitude and good practice. Descriptive and inferential statistics, specifically Fisher’s test were used whenever appropriate.

Among 213 study participants, 140 (65.73%) demonstrated a high level of knowledge towards HIV/AIDS among doctors, nurses, medical technologists, and radiologic technologists. There were 161 (75.59%) who exhibited positive attitude towards HIV/AIDS and worked as pharmacists, physical therapists, and dentists. About 154 (72.30%) reported having fair practices on HIV/AIDS.

The healthcare workers in our study have a high level of knowledge, positive attitude, and fair practices towards HIV/AIDS with significant differences between professions. There is a significant association between professions with the level of knowledge, attitudes, and practices towards HIV. Doctors, nurses, medical technologists, and radiologic technologists have higher level of knowledge on HIV/AIDS. Positive attitude was higher among pharmacists, physical therapists, and dentists. Lastly, good practices were highest among midwives.

BACKGROUND

Surgical menopause results in abrupt reduction of ovarian hormones and is linked with heightened risk of cardiovascular diseases as well as, musculoskeletal, neurocognitive, psychiatric and urogenital changes, including sexual dysfunction.

To explore the knowledge, attitude and practices (KAP) of surgically menopause women towards menopause and hormonal replacement therapy (HRT).

A descriptive cross-sectional study conducted from May 2024 to April 2025 among 92 surgically menopause women. Respondents answered a validated questionnaire regarding their KAP on menopause and HRT.

Majority of the respondents were 41-45 (40.2%) and 46-50 (42.4%) years old at the time of surgery. The most common symptoms were hot flashes/night sweats (60.9%) and vaginal dryness (55.45%) with onset occurring more than 12 months after surgery. Participants demonstrated a neutral understanding of both knowledge on menopause and HRT (mean score 3.03, 2.96). A notable finding was their limited awareness of HRT’s effectiveness in treating hot flashes (mean score 2.76), contrasting with a stronger belief in its cosmetic benefits, (mean score 3.15). Attitudes toward menopause and HRT were also neutral. The primary factor influencing HRT use was physician’s recommendations. While approximately half of the women discussed the surgical induction of menopause and the need for HRT, only 47.8% were prescribed HRT.

Majority of women have fair knowledge on menopause and HRT. Women are not fully familiar with the uses of HRT. The neutral responses across the KAP points the need for educational intervention for fostering a more informed and empowered patient population.