Environmental Health and Preventive Medicine  2010;15(2):121-123

doi:10.1007/s12199-009-0112-y

Development of a new disinfectant with very strong anti-influenza viral activity: a preliminary report.

Hiroki TAKAKUWA 1 ; Toshiyuki MARUOKA ; Tadayo HATA ; Masaaki MIYAZAWA ; Tomoyo HATA ; Hitoshi TOSHIMORI ; Koichi OTSUKI

Affiliations

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Country

Japan

Language

English

Abstract

OBJECTIVESWe evaluated the effectiveness and safety of a disinfectant newly developed by our laboratories for use against influenza viruses.

METHODSThe effectiveness of our new disinfectant against avian, swine and human influenza viruses was tested in ovo. The acute toxicity of this disinfectant to two different cultured cell lines was investigated.

RESULTSThis new disinfectant showed very strong anti-influenza viral activity in the in ovo tests. All of the influenza viruses tested were inactivated very quickly. Following exposure to the disinfectant, the infectivity of all viral strains tested had been eliminated within ≤10 min. The infectant showed a weak acute toxicity in vitro.

CONCLUSIONThis new disinfectant is expected to be useful for preventing viral infection during a new influenza pandemic.