Journal of Korean Breast Cancer Society  1998;1(1):45-53

doi:10.4048/jkbcs.1998.1.1.45

Prognostic Significance of Cathepsin-D Expression in Breast Cancer.

Yong Tae KWON 1 ; Chap Joong JUNG ; Young Hoon KIM ; Sae Hun CHO ; Sang Soom KIM ; Sook Hee HONG

Affiliations

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Keywords

Breast cancer; Cathepsin-D

Country

Republic of Korea

Language

Korean

Abstract

Mouse monoclonal antibody was used for this study. This study was undertaken to define the prognostic value of the expression of Cathepsin-D in 121 breast cancer patients. The results were as follows: 1) Overall, 53.7% of patients were positive for Cathepsin-D 2) Positive staining did not correlate with age, estrogen receptor status,tumor size, axillary nodal status, tumor stage, menopausal status, pathologic grade, DNA ploidy and S-phase fraction.