The angiographic appearances and therapeutic effects of intra-arterial infusion chemotheropy of 42 patients with advanced cardiac carcinoma were analysed.148 intra-arterial infusion chemotherapies were performed for all patients of which all confirmed by pathology. The effective rate of treatment was 85.7% without complications.In this series,the angio- graphic manifestations including moderate hypervascularity and tumor staining(29 cases 69%). encasement of gastric wall arterioles(28 cases 67%),enlargement and staining of lymph nodes (21 cases 50%)and hepatic metastases(20 cases 47.6%)were shown.clinical significance of these signs and the affecting therapeutic factors were discussed.The results indicated that this therapeutic method is a safe rapid and effective palliative treatment for the advanced car- diae carcinoma.