Clinical Psychopharmacology and Neuroscience  2017;15(4):407-409

doi:10.9758/cpn.2017.15.4.407

Lithium Intoxication: A Possible Interaction with Moxifloxacin.

Selvi KAYIPMAZ 1 ; Ali Ercan ALTINÖZ ; Nadide Elmas Gülcü OK

Affiliations

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Keywords

Drug interactions; Lithium; Moxifloxacin

Country

Republic of Korea

Language

English

Abstract

Lithium is a well-known treatment for patients with mood disorders. Intoxication by lithium may be lethal particularly in elderly due to altered pharmacokinetics, renal impairment or multiple drug use. We presented a 74-year-old female patient who had been stabile with lithium carbonate 600 mg/day for 5 years and developed lithium intoxication after bronchiolitis. She presented with altered mental status. The neurological signs resolved slowly after lithium and moxifloxacin were stopped immediately and fluid resuscitation administered. Considering possible drug interactions on elderly patients receiving lithium is essential.