Chinese Journal of General Practitioners 2011;10(3):209-211

doi:10.3760/cma.j.issn.1671-7368.2011.03.025

Relationship between total sermn bilirubin and carotid atherosclerosis in type 2 diabetes mellitus

Yao XU ; Tao LIU ; Jie MING ; Yao WANG ; Wensong ZHAI ; Qiuhe JI

Keywords

Diabetes mellitus,type 2; Carotid artery diseases

Country

China

Language

Chinese

Abstract

Ultrasonography examinations were performed for carotid atherosclerosis in 548 patients with type 2 diabetes mellitus (T2DM). Blood glucose, glycosylated hemoglobin, total serum bilirubin, uric acid, total cholesterol ( TC ), triglycerides ( TG), high-density lipoprotein (HDL), low-density lipoprotein (LDL) were measured. Total serum bilirubin level in T2DM patients without carotid atherosclerosis was (13.0±7. 1 )μmol/L, while that was (10. 9 ± 4. 9 )μmol/L in patients with carotid atherosclerosis (P ＜0. 01 ). The logistic analysis showed that total serum bilirubin level was negatively related to the presence of carotid atherosclerosis ( P ＜ 0. 05 ), which indicated that higher level of total serum bilirubin might be a protective factor for macroangiopathy in T2DM.