Chinese Journal of Parasitology and Parasitic Diseases 2000;18(3):173-175

EFFECT OF SCHISTOSOMA JAPONICUM INFECTION ON SERUM TESTOSTERONE LEVELS IN MICE

Hongbin HE ; Ohta NOBUO ; Kawaguchi HITOSHI

Keywords

Schistosoma/aponicum; testosterone; mouse; radioimmunoassay

Country

China

Language

Chinese

Abstract

[Objective] To determine the effect of Schistosoma japonicum infection on the testoterone level in the sera from male C57BL/6 mice. [Methods] Radioimmunoassay was used to examine testosterone levels in sera of 9 male mice experimentally infected with Schistosoma japonicum. [Results] The serum testosterone levels reduced significantly in all experimentally infected animals 45 days after infection, as compared with the uninfected controls. [Conclusion] Infection with Schistosoma japonicum decreases testosterone levels in the mouse host.