Chinese Journal of Marine Drugs 1994;0(04):-

Immunomodulation of lower polypeptide from sea cucumber in mice

Yongling XIE ; Mingyue ZHANG ; Jin ZHANG ; Tong GUAN ; Chunhong ZHAO ; Aiyin ZHENG

Keywords

sea cucumber; humoral immunity; macrophage(phagocyte); NK cells; immunomodulation

Country

China

Language

Chinese

Abstract

Objective To investigate the immunomodulation of lower polypeptide from sea cucumber in mice.Methods Effects of polypeptide from sea cucumber on the immunity were studied by the observation of the serum hemolysins level(HC_(50)),the plaque-forming cell (PFC),the phagocytosis of the phagocytes and the activities of NK cells.Results To compare experiment groups with control group,the enhancement facilitation of HC_(50),PFC,phagocytosis ability of macrophage and activity of NK cell was observed.Conclusion The results indicated that polypeptide from sea cucumber has the function of immunomodulation in mice.