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A Case of Dacryocele with Recurrent Dacryocystitis.

Seung Won CHUNG ; Hyun Woo LIM ; Sang Hag LEE ; Heung Man LEE

Journal of Rhinology.2005;12(1):65-67.

A dacryocele is an uncommon complication of obstruction in nasolacrimal drainage system. It seems to occur as a result of a distal obstruction at the Hasner's valve and an proximal obstruction at the Rosenmuller's valve and has mostly been treated by opthalmologists until now. We present a rare case of dacryocele with recurrent dacryocystitis, which recurred after lacrimal probing and bougination. Dacryocele has been treated successfully through marsupialization under the endoscopic visualization.
Dacryocystitis* ; Drainage ; Lacrimal Duct Obstruction

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A Case of Surgical Treatment of Atrophic Rhinitis: Silastic Implant.

Jae Yong LEE ; Jae Hong PARK ; Jae Min SHIN ; Jang Yul BYUN

Journal of Rhinology.2005;12(1):62-64.

The literature does not report a cure for atrophic rhinitis, but considerable relief of symptoms such as foul odor, crust formation and nasal stuffiness could be given to the patient by surgical treatment, which always involves a method of narrowing the nasal airway. In this report, a review of the surgical technique of silastic implantation, clinical results and follow up is presented. Forty three years old female patient who was diagnosed as primary atrophic rhinitis was treated surgically with silastic implantation. The result was excellent with complete resolution of the major symptoms. There was no complication such as extrusion of implant. We found that the silastic is a readily available and inexpensive material and the surgical procedureis relatively simple to perform and easily revised. We propose silastic implant as a treatment modality of atrophic rhinitis with a review of literatures.
Female ; Follow-Up Studies ; Humans ; Odors ; Rhinitis, Atrophic*

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Two Cases of Angioleiomyoma Arising from the Lateral Nasal Wall.

Chan Soon PARK ; Jung Hae CHO ; Sung Won KIM ; Yong Jin PARK

Journal of Rhinology.2005;12(1):58-61.

Leiomyomas are benign myogenic tumors most commonly found in the uterus, skin, and gastrointestinal tracts. It was less than 1% occurred in the head and neck area. Especially its incidence in the nasal cavity is more rare. This rarity is partly attributable to the fact that smooth muscle is sparsely present in the nasal cavity apart from the walls of blood vessels. Commonly presented symptoms are frequent epistaxis and nasal obstruction. Complete surgical excision is the treatment of choice. Recently we experienced two cases of angioleiomyoma which were found in the lateral wall of nasal cavity, and excisied via alotomy approach.
Angiomyoma* ; Blood Vessels ; Epistaxis ; Gastrointestinal Tract ; Head ; Incidence ; Leiomyoma ; Muscle, Smooth ; Nasal Cavity ; Nasal Obstruction ; Neck ; Skin ; Uterus

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Foreign Body in the Orbit Associated with Blowout Fracture: A Case Report.

Hong Ryul JIN

Journal of Rhinology.2005;12(1):55-57.

An orbital foreign body combined with blowout fracture after blunt trauma to the orbit may be difficult to diagnose clinically and radiologically. The author reports a case of 40-year-old woman who had an unsuspected orbital foreign body after blunt orbital trauma, and initially presumed to have only blowout fracture and conjunctival laceration. Consultation with an ophthalmologist failed to disclose the orbital foreign body and an isolated inferomedial blowout fracture was seen on computed tomography scans with severe diplopia and limitation of eye movement. She was referred to my department for management of the orbital blowout fracture, where a false eyelash was found during the endonasal endoscopic reduction and subsequently successfully removed that resulted in complete resolution of her symptoms. Though it is a rare complication, an orbital foreign body should be suspected considering the mechanism of injury when there are severe and persistent ocular symptoms inconsistent with the degree of the blowout fracture.
Adult ; Diplopia ; Eye Movements ; Female ; Foreign Bodies* ; Humans ; Lacerations ; Orbit*

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Clinical Analysis of Orbital Subperiosteal Abscess.

Seung Won CHUNG ; Jae Gu CHO ; Sang Hag LEE ; Seung Hoon LEE ; Soon Jae HWANG ; Heung Man LEE

Journal of Rhinology.2005;12(1):50-54.

BACKGROUND AND OBJECTIVES: Subperiosteal abscess is one of the most common orbital complications of sinusitis. It occurs secondary to the spread of infection through natural dehesience of orbital wall, bony suture line, and vein. One of serious complications of subperiosteal abscess is permanently decreased visual acuity, and its incidence is reported as 15-30%. The purpose of this study is to assess the clinical features, diagnosis, management, and therapeutic results. MATERIALS AND METHODS: We reviewd retrospectively the medical records of 7 patients with subperiosteal abscess for recent 13 years. Patients were 5 males and 2 females, and the age of patients ranged from 4 to 64 years. RESULTS: 3 cases of subperiosteal abscesses developed in medial wall, 3 cases in superior wall and 1 case in inferior wall. We did successful surgical drainage in 5 patients and 2 cases were treated with intravenous antibiotics only. In case of medial and inferior wall, drainage procedure was done safely by endoscopic sinus surgery. However, in case of superior wall, traditional external approach was used. CONCLUSION: Exact ophthalmologic evaluation and CT finding are important in determinig surgical treatment. Furtehrmore, method of surgical approach depends on the sites of subperiosteal abscess.
Abscess* ; Anti-Bacterial Agents ; Diagnosis ; Drainage ; Female ; Humans ; Incidence ; Male ; Medical Records ; Orbit* ; Retrospective Studies ; Sinusitis ; Sutures ; Veins ; Visual Acuity

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Rhinoplasty Using Postauricular Dermofat Graft.

Chan Hum PARK

Journal of Rhinology.2005;12(1):46-49.

BACKGROUND AND OBJECTIVES: For augmentation and camouflage of dorsum in rhinoplasty, various materials have been used for many years. Among them dermofat graft has been known as a good grafting material to substitute for soft tissue deficiencies. We report 7 cases of successful rhinoplasty using postauricular dermofat graft. MATERIALS AND METHODS: A semicircular incision was made in postauricular area. The harvested amount of dermofat for augmentation and camouflage was slightly more than the exactly calculated amount considering postoperative contraction. In four patients, graft was used to camouflage for postoperative irregularity of nasal dorsum. In three patients, dermofat graft and Gore-Tex(R) were used to augment for postoperative nasal contraction and change skin texture. RESULTS: After 6-15 months of follow-up, all patients showed a satisfactory improvement in nasal contour and non-visible postauricular scar. CONCLUSION: The postauricular dermofat graft is a useful method to improve postoperative irregularity after hump removal and osteotomy, postoperative nasal contraction, and skin texture. In addition, postauricular dermofat graft has the conveniences of same surgical look and easy postoperative dressing.
Bandages ; Cicatrix ; Follow-Up Studies ; Humans ; Osteotomy ; Rhinoplasty* ; Skin ; Transplants*

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Effect of Clarithromycin on Rhinovirus-16 Infection in A549 Cells.

Hyung Kyung JEON ; Hyun Ja KWON ; Sun Yeohl NAM ; Bong Jae LEE ; Yong Ju JANG

Journal of Rhinology.2005;12(1):39-45.

BACKGROUND AND OBJECTIVES: Rhinovirus enters into airway epithelial cells via the membrane bound receptor ICAM-1. Infected epithelial cells secrete the cytokines such as IL-6 and IL-8, which induce neutrophil migration into the epithelium. Clarithromycin has been found to inhibit ICAM-1 production and secretion of IL-6 and IL-8. We hypothesized that these properties of clarithromycin may be applicable in treating rhinovirus infection. MATERIALS AND METHOD: We assayed the effects of clarithromycin on rhinovirus infected A549 cells. ICAM-1 expression was assessed by flow cytometry, and cytokine secretion was assayed by ELISA. The level of viral replication was expressed as viral titer, which was determined through viral culture on MRC-5 cells. RESULTS: The mean fluorescence intensity of ICAM-1 in rhinovirus infected cells decreased from 12.4+/-0.59 to 9.2+/-0.72 after treatment with clarithromycin. The production of IL-1beta, IL-6, and IL-8 was decreased after rhinovirus infected cells were treated with clarithromycin. In the absence of rhinovirus infection, clarithromycin had no effect on ICAM-1 expression or cytokine secretion. The rhinovirus titer in infected cells was 10(3.71) TCID 50 U/ml, which was reduced following clarithromycin treatment to 10(2.14) TCID 50 U/ml. CONCLUSION: These findings suggest that clarithromycin treatment of rhinovirus infected A549 cells inhibited rhinovirus induction of increased ICAM-1 expression, cytokine elaboration, and viral replication.
Clarithromycin* ; Cytokines ; Enzyme-Linked Immunosorbent Assay ; Epithelial Cells ; Epithelium ; Flow Cytometry ; Fluorescence ; Intercellular Adhesion Molecule-1 ; Interleukin-6 ; Interleukin-8 ; Macrolides ; Membranes ; Neutrophils ; Rhinovirus

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The Inhibitory Effect of Anti-P-Selectin, Anti-PSGL-1 and Anti-CD49d Antibodies on Experimental Allergic Airway Inflammation in Mice.

Seok Won PARK ; A Young KIM ; Yong De JIN ; Bon Seok KOO ; Yong Min KIM ; Yong Ho PARK ; Chan Il PARK ; Ki Sang RHA

Journal of Rhinology.2005;12(1):32-38.

BACKGROUND AND OBJECTIVES: Eosinophil recruitment in allergic inflammation is dependent on the interactions between adhesion molecules. The objective of this study was to determine whether blocking of P-selectin glycoprotein ligand-1 (PSGL-1), P-selectin or CD49d adhesion molecules using monoclonal antibodies can reduce eosinophil recruitment in mice with the airway allergy. MATERIALS AND METHODS: Seven different groups of mice were used. One experimental group of mice (group A) served as naive control and sensitized with phosphate-buffered saline (PBS). Six experimental groups of mice (groups B to G) were sensitized to ovalbumin (OVA). The mice in group B were treated with PBS before OVA aerosol challenge and served as positive controls. The mice in other remaining groups were treated with monoclonal antibodies (mAb) against specific adhesion molecules before OVA challenge; anti-P-selectin mAb (group C), anti-PSGL-1 mAb (group D), anti-CD49d mAb (group E), anti-P-selectin mAb & anti-CD49d mAb (group F), anti PSGL-1 mAb & anti-CD49d mAb (group G). Eosinophils in the nasal mucosa and bronchoalveolar lavage (BAL) fluid in each animal group were measured. RESULTS: Mucosal eosinophilic infiltrations were significantly reduced at the mice in the group C, F or G compared with group B. Eosinophils in BAL fluid were significantly reduced only at the group C mice. CONCLUSION: These results suggest that blockade of P-selectin is superior to blockade of PSGL-1 or CD49d in the inhibitory effect against eosinophil recruitment.
Animal Experimentation ; Animals ; Antibodies* ; Antibodies, Monoclonal ; Bronchoalveolar Lavage ; Cell Adhesion Molecules ; Eosinophils ; Glycoproteins ; Hypersensitivity ; Inflammation* ; Mice* ; Nasal Mucosa ; Ovalbumin ; Ovum ; P-Selectin

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A Survey on the Clinical Activity Related with Viral Rhinitis among the Otolaryngic Private Practitioners.

Yong Ju JANG ; You Sam CHUNG ; Bong Jae LEE

Journal of Rhinology.2005;12(1):27-31.

BACKGROUND AND OBJECTIVES: Viral rhinitis has been considered as an important part in the clinical activity of the ENT specialists in private practice. However, the estimate of how big a proportion the viral rhinitis has and how it is being treated in otolaryngic private practitioners has not been published yet. Thus we aimed to investigate these issues in this study. MATERIALS AND METHODS: Four hundred ENT specialists privately practicing in Seoul, Gyeongki, and Choongcheong area were selected. Questionnaire pertaining to the proportion of viral rhinitis patient on their practice and their way of treatment was mailed to the selected doctors. RESULTS: The patients presenting with viral rhinitis symptom constitutes 38.9% of their patient population on the average. Most patients with viral rhinitis visited ENT specialists within 7 day after onset of rhinitis symptom. The mean duration of prescription for the patients not having complication was 4.3 days. The most frequently prescribed medication for viral rhinitis was first generation antihistamine, systemic decongestants, nebulization, and NSAID in order of frequency. The most annoying symptom for the viral rhinitis patients was nasal obstruction. CONCLUSION: The results of this study indicate that viral rhinitis takes an important position in the otolaryngic private practice.
Humans ; Nasal Decongestants ; Nasal Obstruction ; Postal Service ; Prescriptions ; Private Practice ; Rhinitis* ; Seoul ; Specialization ; Surveys and Questionnaires

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Clinical Study of Patients that Rhinoplasty was Performed Concomitantly with Nasal Bone Fracture Reduction.

Chan Hum PARK

Journal of Rhinology.2005;12(1):21-26.

BACKGROUND AND OBJECTIVES: Traditionally nasal bone fracture repair has been performed separately with more refined septorhinoplasty being reserved until all edema and other acute effects of nasal injury have regressed or stabilized. However a question arise whether more involved septorhinoplasty procedures could be done at the same time as nasal bone fracture reduction. But little literature were found in the outcomes. We studied the clinical outcomes of patients that rhinoplasty was performed concomitantly with nasal bone fracture reduction. MATERIALS AND METHODS: We studied 20 patients that septorhinoplasty were performed concomitantly with nasal bone fracture reduction. Doctor's and patient's satisfaction was investigated after minimal 6 months later using visual analogue scale. Operative methods and complications were studied. All results were statistically confirmed. RESULTS: Generally post-operative result was satisfied. But, in a patient with severe fracture, 2nd rhinoplasty was performed for proper correction. Other complications were not found. CONCLUSION: We concluded that septorhinoplasty procedures was done at the same time as nasal bone fracture reduction showed good result in selective cases.
Edema ; Humans ; Nasal Bone* ; Rhinoplasty*

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