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Clinical effect of semiconductor laser combined with total glucosides of paeony capsules for the treatment of erosive oral lichen planus

GONG Zhendong ; FANG Fuchun ; LIU Liyan ; WU Buling

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(11):712-716. doi:10.12016/j.issn.2096-1456.2018.11.005

Objective : To investigate the short-term clinical effect of semiconductor laser exposure combined with total glucosides of paeony (TGP) capsules for the treatment of erosive oral lichen planus (OLP). Methods: Sixty-four patients with erosive oral lichen planus were randomly divided into two groups: the experimental group and the control group. Patients in the control group were treated with TGP capsules, while patients in the experimental group were treated with TGP capsules and semiconductor laser irradiation. The clinical effects were evaluated 3 months after treatment. The data were analyzed using the SPSS 17.0 software package. Results : Three months after treatment, the effective rate in the experimental group was 90.6%, which was significantly higher than that in the control group (59.4%, χ 2=5.62, P < 0.05). The physical condition and visual analogue scale (VAS) scores in the experimental group were 2.17 ± 1.49 and 1.25 ± 1.29, respectively. The physical condition and VAS scores in the control group were 3.55 ± 1.41 and 2.09 ± 1.24, respectively. The physical condition and VAS scores in both groups were significantly higher after treatment than before (P < 0.05). Three months after treatment, the physical condition score (t=3.805) and VAS score (t=2.655) in the experimental group were significant higher than those in the control group (P < 0.05). Conclusion Semiconductor laser irradiation combined with TGP capsules can improve the short-term clinical efficacy in the treatment of erosive OLP.

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CBCT detection of the incidence of middle mesial canal and isthmus in the mandibular first molar

LIU Zhongjun ; ZHANG Zhiyong ; KUANG Ruifang ; ZENG Xiongqun ; LU Yu ; XU Shuaimei

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(11):717-721. doi:10.12016/j.issn.2096-1456.2018.11.006

Objective : To analyze the morphology and incidence of middle mesial canal (MM) and isthmus in the mandibular first permanent molar by cone-beam computed tomography (CBCT). Methods: Statistical analysis was performed on images from patients who underwent CBCT examination in the Department of Radiology at Stomatological Hospital, Southern Medical University. Samples exhibiting root canal treatment, root resorption and calcification were excluded. Data regarding sex, age, the presence or absence of isthmus and MM, and the number of roots and root canals were recorded. Results : Of the 217 mandibular first molar samples, 8 (3.7%) had an MM, and 2 (0.9%) had an independent apical foramen. The overall incidence rate of isthmus was 57.1%; this rate was 50.7% in the cervical third of the root canal, 17.5% in the middle third, and 13.4% in the apical third. The incidence rate of isthmus was 61.8% on the left side, 52.3% on the right side, 58.7% in males, and 55.8% in females. No significant difference was found between the left and right sides or between females and males (P > 0.05). The incidence rate of isthmus in people under 60 was greater than 50% but was significantly lower in people older than 60. Conclusion Only a very small proportion of MMs have an independent apical foramen in the mandibular first molar. The incidence of isthmus in the mesial root of the mandibular first permanent molar is high, and isthmus usually occurs in the cervical third of the root canal. During root canal treatment or apical surgery, attention should be given to the physical and chemical preparation of the isthmus.

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Coronally advanced flap combined with connective tissue grafts for the treatment of mandibular anterior teeth gingival recession

YE Xiaoyi ; LIU Nanyou ; HUANG Yanhong ; LU Haibin ; RONG Mingdeng

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(11):722-726. doi:10.12016/j.issn.2096-1456.2018.11.007

Objective : To compare the effect of the combined coronally advanced flap and connective tissue flap techniques with that of a guided tissue regeneration (GTR) technique on recovering the exposed root surface in a case of gingival retraction over the lower anterior teeth. Methods: A case of gingival recession (Miller Ⅲ type) over teeth 33-43 accompanied by hypersensitivity of the right lower teeth was treated using different techniques bilaterally. Teeth 42-43 were treated by a combined coronally advanced flap and connective tissue flap technique, while teeth 33-41 were treated by a GTR technique of a coronally advanced flap combined with an absorbable collagen membrane. Results : Teeth 42-43 exhibited ideal gingival recovering of the exposed root surface, with the disappearance of the hypersensitivity symptoms, during the follow-up visits at 3.5 months after surgery. However, the exposed root surface of teeth 33-41 exhibited no significant change in coverage at the same time points compared with the preoperative coverage. At 12 months after surgery, the recovered gingiva on the root surface of teeth 42-43 was stable. Conclusion The combined coronally advanced flap and connective tissue flap approach, which can achieve better coverage of the exposed root surface than the GTR technique, is a feasible and safe surgical method for treating cases with gingival recession. The GTR technique is not an effective method for treating cases with Miller Ⅲ type gingival recession over multiple teeth due to proximal attachment loss.

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The functional and aesthetic reconstruction of tetracycline stained teeth with a virtual articulator in a CAD/CAM system

TAN Shuyi ; CHEN Yifan

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(11):727-733. doi:10.12016/j.issn.2096-1456.2018.11.008

Objective: To investigate the reliability of using virtual articulator in the fabrication of zirconia crowns for tetracycline discolored teeth. Methods: To treat the patient with serious tetracycline stained teeth, we use zirconia crowns to shield the stained abutment teeth. To retain the characteristics of patient′s original occlusal contacts, meanwhile, to establish a stable and evenly distributed occlusal contacts, we recorded the functional movements of the patient′s jaw before preparing the teeth and transferred this relations to a physical articulator. Afterwards, relationship of the upper and lower arches was scanned through a specified fixature. Then we can customized the fabrication of the occlusal contacts of the restorations conveniently and efficiently with virtual articulator in CAD/CAM system. Results: When the final restorations were inserted , a charming smile was achieved on patient′s face with satisfactory esthetics. With the application of virtual articulator in designing process, we made evenly distributed and stable bilateral occlusal contacting spots, smooth protrusive and lateral guidance on the lingual aspects of the upper anteriors. One year follow-up, this patient was observed in good oral hygiene, and was satisfied with her esthetic and functional outcome. The soft tissue around the restorations was assessed to be healthy and no signs of inflammation. Conclusion Applying the virtual articulator kits in CAD/CAM system in designing and fabricating the function-driven restorations could be an efficient way to obtain an satisfactory long-term outcome.

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The antimicrobial activity and application of graphene quantum dots in oral medicine

ZHANG Xiliu ; WEI Changbo ; YU Dongsheng

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(11):734-737. doi:10.12016/j.issn.2096-1456.2018.11.009

The abuse of antibiotics has been increasing bacterial resistance, which means there is a need to develop methods for the efficient detection and effective treatment of multiresistant bacterial infections. As one of graphene-based materials, graphene quantum dots (GQDs) have distinct mechanical, electrical, and optical properties, including a small size, a large surface area-to-volume ratio, biocompatibility, antimicrobial activity and tunable photoluminescence. Therefore, GQDs are expected to be widely used as antimicrobial materials, drug delivery carriers and photosensitizers in antibacterial applications. In this review, we focus on their synthesis, characteristics and antimicrobial applications in oral medicine.

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Application of electrospun nanofibrous scaffolds in pulp regeneration

ZHANG Qianli ; YUAN Chongyang ; WANG Xiaoyan

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(11):738-742. doi:10.12016/j.issn.2096-1456.2018.11.010

Electrospinning technology is currently the only technology capable of directly and continuously preparing polymer nanofibers. It can prepare a variety of nanofibers with different characteristics by using high voltage electrostatic field. These electrospun nanofibers have an inherently high porosity, high surface-to-volume ratio and good mechanical properties, allowing the engineering of scaffolds with a nanoscale topography and high porosity similar to that of the natural extracellular matrix (ECM) to facilitate cell attachment, migration, proliferation, differentiation and functional expression. Thus, electrospun nanofibers have been widely applied in tissue engineering for different purposes such as bone, cartilage, neural, vascular, and skin regeneration and are being developed for pulp regeneration. This review briefly describes the preparation process and biological characteristics of electrospun nanofibers; furthermore, the most recent and state-of-the-art work on electrospun nanofibrous scaffolds, primarily their composition and structure in pulp tissue engineering, is introduced.

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Clinical study of the removal of infratemporal fossa and pterygopalatine fossa foreign bodies using a trans-oral approach

LIU Junping ; YI Chen ; WANG Jianguang

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(4):231-235. doi:10.12016/j.issn.2096-1456.2018.04.006

Objective : To summarize the clinical experience of removing infratemporal fossa and pterygopalatine fossa foreign bodies via a trans-oral approach. Methods: The clinical data of 9 patients with foreign bodies in the infratemporal fossa and pterygopalatine fossa hospitalized from March 2008 to June 2017 were analyzed retrospectively. Among these cases, 4 were flying injuries, 2 were falling injuries, 2 were traffic injuries and 1 was an iatrogenic syringe injury. Foreign bodies were divided into the following categories: 3 cases of wood from branches, 3 cases of iron filings, 2 cases of broken glass, and one case of a broken syringe needle. Before surgery, all subjects underwent spiral CT three-dimensional reconstruction and CT angiography examinations. After accurately determining the relationship between the foreign body and the internal and external carotid arteries and their branches, patients underwent an operation under general anesthesia to remove the foreign body via a trans-oral approach. In addition, patients participated in mouth opening training for one week. Then, patients were followed for 1 to 6 months. Foreign bodies were removed completely in all 9 patients. Results: Foreign bodies were independently located in the pterygopalatine fossa in 2 cases and in the in fratemporal fossa in 3 cases. There were 4 cases of foreign bodies located in both the infratemporal fossa and the pterygopalatine fossa. All 9 patients had the foreign bodies completely removed and were discharged one week after surgery. They were followed for 1 to 6 months. Their mouth opening and occlusion were normal, without any complications. Conclusion Spiral CT, 3D reconstruction and CT angiography examinations are necessary and important for accurate pre-operation positioning. It is feasible to remove foreign bodies in the infratemporal fossa and pterygopalatine fossa via a trans-oral approach.

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Study of event-related potentials in school-age children with cleft palate

SHU Huang ; YANG Feng ; WANG Ji ; XIAO Yuhan ; DING Guicong

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(4):236-239. doi:10.12016/j.issn.2096⁃1456.2018.04.007

Objective : To investigate possible functional disorders of central auditory processing and language in school-age children with cleft palate through an assessment of the characteristics of the P300 and N400 event-related potentials (ERPs). Methods : This study included 28 school-age children with cleft palate, aged 6 to 12 years, and 30 children without cleft palate as a control group. The P300 and N400 ERPs were selected as indexes of the central auditory processing and language functions of children in both groups. The data were statistically compared between the two groups. Results : Compared with the controls, the children with cleft palate showed a significantly prolonged P300 latency (331.73 ± 14.94 ms vs. 348.64 ± 14.66 ms, P < 0.05) and a significantly decreased P300 amplitude (13.47 ± 2.24 μV vs. 12.07 ± 2.46 μV, P < 0.05). Similarly, the N400 latency of children with cleft palate was significantly prolonged compared to that of controls (431.07 ± 17.90 ms vs. 408.23 ± 18.04 ms, P < 0.05), and the N400 amplitude was significantly decreased compared to that of controls (13.75 ± 2.12 μV vs. 15.17 ± 2.34 μV, P < 0.05). Conclusion School-age children with cleft palate may have central auditory processing disorders and language dysfunctions.

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The effects of intramuscular injections of vitamin B1 and B12 on pain, salivary components and taste in patients with burning mouth syndrome

YU Xixi ; Lü ; Jian ; WANG Caixia ; WANG Yiheng ; DENG Songsong ; LI Lulu ; WANG Wanchun

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(4):240-244. doi:10.12016/j.issn.2096-1456.2018.04.008

Objective: To determine differences in pain, salivary components and taste between burning mouth syn⁃ drome (BMS) patients and the normal population and to study the effects of intramuscular injections of vitamin B1 (VitB1) and vitamin B12 (VitB12) on BMS. Methods: Before treatment: We observed and compared differences in un⁃ stimulated salivary flow rate (USFR); stimulated salivary flow rate (SSFR); salivary amylase, cortisol, and secretory im⁃ munoglobulin A (SIgA) concentrations; and taste levels between BMS patients and normal controls. After treatment: The treatment group received an intramuscular injection of 100 mg VitB1 and 0.5 mg VitB12 in the buttocks once per day for 10 days. The above indexes were recorded before and after treatment and compared. A visual analog scale (VAS) score was used to assess the degree of pain relief in patients and as a clinical evaluation index. Results: Before treat⁃ ment: SSFR, salivary amylase levels and bitter taste levels of the treatment group were significantly lower than those of the control group (P < 0.05). The concentration of SIgA was significantly higher than that of the control group (P < 0.05), and the USFR and the cortisol concentration were not significant different from the those of the control group (P > 0.05). After treatment: The total effective rate of VitB1 and VitB12 on BMS was up to 70%. USFR was increased signifi⁃ cantly after treatment (P < 0.05), and the concentration of SIgA decreased (P < 0.05). There were no significant differ⁃ ences in the SSFR or the cortisol and salivary amylase concentrations (P > 0.05). Taste levels improved by varying de⁃ grees. Conclusions The abnormal decreases in SSFR, salivary amylase levels, and taste sensitivity and the abnormal increase in SIgA levels seen in BMS patients may be sensitive salivary indicators for the diagnosis of BMS. A VitB1 and VitB12 intramuscular injection is an effective treatment for patients with BMS, who showed pain relief. Changes in SIgA levels may be used as an indicator during follow⁃up and for the prognosis of BMS patients.

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The effects of two different patterns on the precision of zirconia all-ceramic crowns

ZHANG Juan ; LI Dongjian ; JIANG Jie ; SITU Yan ; ZOU Shuangshuang ; WEN Xingtao

Journal of Prevention and Treatment for Stomatological Diseases.2018;26(4):245-249. doi:10.12016/j.issn.2096⁃1456.2018.04.009

Objective: The objective of this study was to compare the early clinical effects of zirconia all⁃ceramic crowns using two different impression methods. Zirconia ceramic crowns were produced using digital models based on either a silicone rubber impression perfusion model in vitro or a 3D mouth scanner. Methods : A total of 50 patients with a planned restoration of the first permanent molar with zirconia all⁃ceramic crowns after root canal therapy were se⁃ lected and randomly divided into two groups: a digital impression by intraoral 3D scanning group and a digital impres⁃ sion by extraoral scanning after silicone rubber impression group. Zirconia all⁃ceramic crowns were created by CAD/ CAM in both groups. Marginal adaptation, proximal contact, and occlusal contact were compared between groups. Results: There was no significant difference between the two groups in marginal adaptation (P > 0.05). For proximal con⁃ tact and occlusal contact, no significant differences regarding the number of cases for the criteria of level A and level B were found between two groups (P > 0.05), while the misfit value in level B was smaller in the first group than in the second group (P < 0.05). Conclusion Zirconia all⁃ceramic crowns with intraoral 3D scanning show excellent early clinical performance.

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