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A Case of Malignant Transformation of Layngeal Mucosa after Inhalation Injury 25 Years Ago.

Jae Young LEE ; GilJoon LEE ; Dongbin AHN ; Jin Ho SOHN

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):144-147.

Laryngeal neoplasm is the second most common malignancy of the upper aerodigestive tract. About 85% to 95% of laryngeal malignancies are squamous cell carcinoma that arises from the epithelial lining of the larynx. The exact cause of laryngeal neoplasm is unknown, but certain risk factors can affect the chances of developing it. Chronic inflammation is a mutagen factor confirmed in the carcinogenesis of various tumor. Inhalation injuries cause histopathologic damage to laryngeal mucosa and inflammation change. This long term inflammation may leads to the development of dysplasia and malignant transformation. Recently, we experienced a case of malignant transformation of laryngeal mucosa after inhalation injury patient 25 years ago. Herein, we reported this rare case and review the relevant literature.
Burns ; Carcinogenesis ; Carcinoma, Squamous Cell ; Humans ; Inflammation ; Inhalation* ; Laryngeal Mucosa ; Laryngeal Neoplasms ; Larynx ; Mucous Membrane* ; Risk Factors

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A Case of Laryngeal Pleomorphic Adenoma.

Sang Hun LEE ; Seung Ho CHOI

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):141-143.

Pleomorphic adenoma is the most common salivary gland neoplasm and most of them arise in the parotid gland. Pleomorphic adenomas at other sites than salivary glands have rarely been reported. We experienced a patient with pleomorphic adenoma of larynx. A 59 year-old female patient visited outpatient clinic complaining of voice change and foreign body sensation. Round mass at right vocal process was found in laryngoscopic exam. We performed laryngoscopic microsurgery to remove the tumor. Histologically, it was diagnosed as pleomorphic adenoma. Recurrence or complication did not occur during the follow up period of 3 years.
Adenoma, Pleomorphic* ; Ambulatory Care Facilities ; Female ; Follow-Up Studies ; Foreign Bodies ; Humans ; Larynx ; Microsurgery ; Parotid Gland ; Recurrence ; Salivary Gland Neoplasms ; Salivary Glands ; Sensation ; Voice

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A Case of Foreign Body in Larynx Involving Thyroid.

Ju Hyun HAN ; Kyu Sung CHOI ; Pyung Ahn AHN ; Gi Cheol PARK

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):138-140.

Pharyngeal and laryngeal foreign bodies are common problem at ENT clinic. Removal of a foreign body is mostly simple with the manipulation of endoscope and various instruments. Rarely, migration of swallowed sharp foreign body makes complication. We describe a 74-year-old patient diagnosed with foreign body in larynx involving thyroid. In this case, we present this disease and the treatment course which has been successfully treated by surgical removal and conservative treatment. Furthermore, we discuss its symptoms, physical examinations through literature review.
Aged ; Endoscopes ; Foreign Bodies* ; Humans ; Larynx* ; Physical Examination ; Thyroid Gland*

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A Case of Venous Malformation of the Pyriform Sinus Treated with Ethanol Sclerotherapy.

Yeon Jun YANG ; Min Su KANG ; Sang Hyub KIM ; Jeong Hwan MOON

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):135-137.

We describe a case of venous malformation of pyriform sinus in 63 year-old patient, discovered incidentally. Venous malformation are the most common vascular malformations to arise in the head and neck. However venous malformation of the hypopharynx in the adult papulation are rare. The author performed successfully ethanol sclerotherapy for venous malformation of pyriform sinus, so we present the case with a review of the related literatures.
Adult ; Ethanol* ; Head ; Humans ; Hypopharynx ; Neck ; Pyriform Sinus* ; Sclerotherapy* ; Vascular Malformations

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Surgical Treatment of Sulcus Vocalis Using KTP Laser.

Chan Min JUNG ; Jihyung KIM ; Jae Yol LIM ; Hong Shik CHOI

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):131-134.

Sulcus vocalis remains a surgical challenge despite many recent advances in laryngomicrosurgeries. We previously reported that 585-nm Pulsed dye laser (PDL) exerts favorable outcome in treatment of sulcus vocalis due to its therapeutic effects of collagen rearrangement and improved wound remodeling. In spite of the usefulness of PDL glottoplasty for treating sulcus vocalis, the device is no more available in the country. It prompted us to focus another angiolytic laser ; 532-nm KTP laser which has similar mechanisms of action and has been used for treatment of other laryngeal lesions elsewhere. Herein, we present a case of sulcus vocalis successfully treated with KTP laser. A patient underwent laryngomicrosurgery with angiolytic KTP laser (KTP glottoplasty) by the same surgical procedure with PDL glottoplasty. After the surgery, the patient presented improved voice outcome in time without complications.
Collagen ; Humans ; Laryngoscopy ; Lasers, Dye ; Lasers, Solid-State* ; Therapeutic Uses ; Voice ; Voice Disorders ; Wounds and Injuries

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A Case of Sarcomatoid Carcinoma of the Larynx Mimicking Vocal Polyp.

Taehoon KIM ; GilJoon LEE ; Jin Ho SOHN

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):128-130.

Sarcomatoid carcinomas are biphasic tumors which have surface epithelial changes and an underlying spindle-shaped neoplastic proliferation. A 62-year-old male with hoarseness came to our hospital for evaluation. A single smooth polypoid lesion was detected on his right true vocal fold by larnygoscope. The patient was diagnosed with vocal polyp and treated with surgical excision. Pathology report of the excised specimen was compatible with sarcomatoid carcinoma. Therefore, further surgical resection was performed to secure safety margins. We report a case of a sarcomatoid carcinoma patient who was clinically diagnosed as vocal polyp.
Hoarseness ; Humans ; Larynx* ; Male ; Middle Aged ; Pathology ; Polyps* ; Vocal Cords

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Effectiveness of Proton Pump Inhibitor in the Treatment of Contact Granuloma.

Dong Hwan KIM ; Keon Ho KIM ; Seon Min JUNG ; Chang Myeon SONG ; Yong Bae JI ; Kyung TAE

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):123-127.

BACKGROUND AND OBJECTIVES: Contact granuloma is granulation tissue that occurs mainly in the vocal process of arytenoid cartilage. Among several etiological factors, gastric acid reflux is known to be an important cause. The aim of this study was to evaluate clinical characteristics of contact granuloma and analyze the effectiveness of proton pump inhibitor in the treatment of contact granuloma. MATERIALS AND METHODS: We retrospectively reviewed the medical records of 40 patients who were treated with proton pump inhibitor (PPI) for contact granuloma from January 2011 to December 2015. Reflux finding score (RFS), reflux symptom index (RSI) and size of granuloma were evaluated before and after treatment serially to assess the effectiveness of proton pump inhibitor. RESULTS: Of 40 patients, 25 patients (62.5%) and 10 patients (25%) showed improvement and partial improvement of granuloma, respectively. Five patients showed no response. The mean times of partial improvement and improvement were 2.08±2.23 months and 4.60±2.77 months, respectively and mean duration of PPI treatment was 6.8±5.2 months. CONCLUSION: Proton pump inhibitors is effective in the treatment of contact granuloma.
Arytenoid Cartilage ; Gastroesophageal Reflux ; Granulation Tissue ; Granuloma* ; Humans ; Laryngopharyngeal Reflux ; Medical Records ; Proton Pump Inhibitors ; Proton Pumps* ; Protons* ; Retrospective Studies

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Comparison of Voice Outcomes between Medialization Thyroplasty and Arytenoid Adduction with or without Injection Laryngoplasty in Unilateral Vocal Fold Paralysis Patients.

Hokyung JIN ; Seong Jun WON ; Nayeon CHOI ; Young Ik SON

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):118-122.

BACKGROUND AND OBJECTIVES: In unilateral vocal fold paralysis (VFP), medialization thyroplasty (MT), arytenoid adduction (AA) and injection layrngoplasty (IL) are the most common procedures to correct phonatory problems. There is no consensus that which procedure is superior to the other for correcting the glottal insufficiency. The purpose of this study was to compare the phonatory parameters between MT, AA and AA with IL (AA+IL) in patients with unilateral VFP. MATERIALS AND METHODS: This retrospective study enrolled patients from 2005 to 2016. Total 72 patients (49 male, 23 female, mean age 54.5 years) were classified into three groups ; MT (n=28), AA (n=12), and AA+IL (n=32). GRBAS scales, maximum phonation time (MPT), jitter, shimmer, noise to harmonic ratio (NHR), and voice handicap index (VHI)-10 and VHI-30 were preoperatively and postoperatively collected and compared between the three groups. RESULTS: Age, gender and cause of VFP were not significantly different between the three groups. In MT and AA groups, MPT, VHI, G (overall grade) and B (breathiness) were significantly improved. In AA+IL group, jitter, shimmer, NHR, MPT, VHI, G and B were significantly improved. In analysis of differences (pre-postoperative values), Δ jitter (p < 0.001), Δ shimmer (p=0.031), and Δ NHR (p=0.002) were significantly different and AA+IL group showed the greatest improvement. CONCLUSION: Analysis of voice parameters showed that all the three procedures for patients with unilateral VFP are effective in the improvement of voice ; especially in MPT, VHI-10, G and B scales. Compared to the others, AA+IL provided the better acoustic values including jitter, shimmer and NHR.
Acoustics ; Consensus ; Female ; Humans ; Laryngoplasty* ; Male ; Noise ; Paralysis* ; Phonation ; Retrospective Studies ; Vocal Cords* ; Voice* ; Weights and Measures

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Comparison of Initial Therapeutic Effects of Voice Therapy and Injection Laryngoplasty for Unilateral Vocal Cord Paralysis Patients.

Chang Yoon LEE ; Soo Youn AN ; Hyun CHANG ; Hee Young SON

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):112-117.

BACKGROUND AND OBJECTIVES: The purpose of this study was to classify patients with unilateral vocal fold paralysis according to their fixed location and to analysis the effects of two treatment methods by early voice therapy and injection laryngoplasty. MATERIALS AND METHODS: Twenty patients who were classified as full abduction and slight abduction according to the position of paralysis were treated injection laryngoplasy, and 23 patients were treated by voice therapy. Twenty patients were treated injection laryngoplasy and 23 patients were treated voice therapy. Results were evaluated by acoustic analysis, electroglottography, cepstrum analysis before and after therapy. The voice therapy was conducted by improving the larynx movement and glottal contact, whilst removing hypertension of the supraglottic and use the breathing. RESULTS: Significant improvement was found in the acoustic parameter, cepstrum parameter, and EGG before and after treatment in both groups. There was no significant difference between the two groups when compared before and after treatment to compare the effects of injection laryngoplasty and voice therapy. CONCLUSION: The initial treatments for unilateral vocal cord paralysis are injection laryngoplasty and voice therapy. however, there is no precise standard about which method should be applied first. Therefore, in this study, we tried to classify patients according to their paralysis position and then apply two methods. The results of this study suggest that voice therapy and Injection laryngoplasty at the initial stage is a very useful method to improve voice quality of vocal fold paralysis and improve laryngeal function.
Acoustics ; Humans ; Hypertension ; Laryngoplasty* ; Larynx ; Methods ; Ovum ; Paralysis ; Respiration ; Speech Therapy ; Therapeutic Uses* ; Vocal Cord Paralysis* ; Vocal Cords ; Voice Quality ; Voice*

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Auditory-Perceptual and Acoustic Evaluation in Measuring Dysphonia Severity of Vocal Cord Paralysis.

Geun Hyo KIM ; Yeon Woo LEE ; Hee June PARK ; In Ho BAE ; Byung Joo LEE ; Soon Bok KWON

Journal of the Korean Society of Laryngology Phoniatrics and Logopedics.2017;28(2):106-111.

BACKGROUND AND OBJECTIVES: The purpose of this study was to investigate the criterion-related concurrent validity of two standardized auditory-perceptual assessments and the Acoustic Voice Quality Index (AVQI) for measuring dysphonia severity in patients with vocal cord paralysis (VCP). MATERIALS AND METHODS: Total 210 patients with VCP and 236 normal voice subjects were asked to sustain the vowel [a:] and to read aloud the Korean text “Walk”. A 2 second mid-vowel portion of the sustained vowel and two sentences (with 26 syllables) were recorded. And then voice samples were edited, concatenated, and analyzed according to Praat script. Two standardized auditory-perceptual assessment (GRBAS and CAPE-V) were performed by three raters. RESULTS: The VCP group showed higher AVQI, Grade (G) and Overall Severity (OS) values than normal voice group. And the correlation among AVQI, G, and OS ranged from 0.904 to 0.926. In ROC curve analysis, cutoff values of AVQI, G, and OS were < 3.79, < 0.00, and < 30.00, respectively, and the AUC of each analysis was over .89. CONCLUSION: AVQI and auditory evaluation can improve the early screening ability of VCP voice and help to establish effective diagnosis and treatment plan for VCP-related dysphonia.
Acoustics* ; Area Under Curve ; Diagnosis ; Dysphonia* ; Humans ; Mass Screening ; ROC Curve ; Vocal Cord Paralysis* ; Vocal Cords* ; Voice ; Voice Quality

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