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A Child of Palatal Myoclonus Tinnitus Treated with Intraoral Injection of Botulinum Toxin.

Kyu Hwan JUNG ; Moo Jin BAEK ; Yong Wan KIM ; Geun Yeol JO

Korean Journal of Otolaryngology - Head and Neck Surgery.2012;55(8):530-534. doi:10.3342/kjorl-hns.2012.55.8.530

Palatal myoclonus (palatal tremor) was reported to be presented with a sole symptom of objective pulsating tinnitus and could be controlled by botulinum toxin injection alone. However, there were 3 cases reported in Korea of palatal myoclonus tinnitus controlled with botulinum toxin injection through the dual administration route of the mouth and nasal cavity. We present an 11-year-old boy of essential palatal myoclonus tinnitus, which was controlled by intraoral botulinum toxin injection to the tensor veli palatini muscle alone. Intraoral injection of botulinum toxin to the anatomical location of tensor veli palatini muscle with the guidance of electromyography was effective and safe for the child of objective tinnitus caused by palatal myoclonus.
Botulinum Toxins ; Child ; Electromyography ; Humans ; Korea ; Mouth ; Muscles ; Myoclonus ; Nasal Cavity ; Tinnitus

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A Case of Ectopic Tooth in the Maxillary Sinus Associated with a Mucocele.

Tae Yong KIM ; Byeong Jin KIM ; Seong Kook PARK

Korean Journal of Otolaryngology - Head and Neck Surgery.2012;55(8):527-529. doi:10.3342/kjorl-hns.2012.55.8.527

Supernumerary, ectopic tooth eruption in a non-dental area is a rare entity. The ectopic development of tooth found in non-dental environment has been reported in places such as the nasal cavity, chin, maxillary sinus, mandibular bone, palate and orbital cavity. Ectopic tooth eruptions in the maxillary sinus are usually asymptomatic and are found incidentally during routine clinical or radiological investigations. The diagnosis is usually made by plain-film radiography. Computed tomography is indicated when an ectopic tooth is found prior to surgery. Standard treatment for an ectopic tooth is extraction of the tooth. Here, the authors present a case of supernumerary, ectopic tooth found in the maxillary sinus associated with a mucocele.
Chin ; Maxillary Sinus ; Mucocele ; Nasal Cavity ; Orbit ; Palate ; Tooth ; Tooth Eruption, Ectopic

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A Case of Cavernous Hemangioma in the Parapharyngeal Space as a Neurogenic Tumor.

Ji Eun CHOI ; Yang Sun CHO

Korean Journal of Otolaryngology - Head and Neck Surgery.2012;55(8):521-526. doi:10.3342/kjorl-hns.2012.55.8.521

Hemangiomas are the most common benign neoplasms, which frequently involve the region of head and neck. However, cavernous hemangiomas are extremely rare in the parapharyngeal space and there has been only a few case reports regarding the disease found in this region. Recently, we experienced a 57-year-old female patient with cavernous hemangioma involving the infratemporal fossa and parapharyngeal space. This case was surgically managed using the infratemporal fossa approach type B. Preoperatively, it was difficult to differentiate the mass of cavernous hemangioma from a neurogenic tumor and this led to a massive bleeding during the operawtion. The preoperative decision-making process and the role of diagnostic imaging were discussed with literature reviews.
Caves ; Diagnostic Imaging ; Female ; Head ; Hemangioma ; Hemangioma, Cavernous ; Hemorrhage ; Humans ; Middle Aged ; Neck

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Tubular Apocrine Adenoma with Syringocystadenoma Papilliferum of the External Auditory Canal.

Min Suk KANG ; Ju Shin LIM ; Sang Yoo PARK ; Min Seob EOM

Korean Journal of Otolaryngology - Head and Neck Surgery.2012;55(8):518-520. doi:10.3342/kjorl-hns.2012.55.8.518

Tumors that develop from external auditory canal (EAC) are very rare. Adenoma that originates from apocrine is also a rare entity found in the EAC. Nevus sebaceous, syringocystadenoma papilliferum (SCAP), tubular apocrine adenoma (TAA), and fibroadenoma are known to originate from apocrine. Among them, SCAP is believed to be a benign tumor that is manifested as papule and plague on the scalp and the face. However, TAA is a rare intradermal eccrine tumor and it mostly manifests as an isolated single nodule within the scalp area. Generally, these tumors are considered as two separate entities. Many articles have reported on the prevalence of TAA or SCAP with nevus sebaceous on the body, extremities, and scalp; but only 2 articles were reported on tumors that developed from EAC. In this article, we report on a patient who presented a mass in EAC, with both SCAP and TAA pathohistologic finding without nevus sebaceous.
Adenoma ; Aminocaproic Acids ; Apocrine Glands ; Ear Canal ; Extremities ; Fibroadenoma ; Humans ; Nevus ; Plague ; Prevalence ; Scalp

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Two Cases of the Inverted Papilloma in the Maxillary Sinus Treated by Modified Transnasal Endoscopic Medial Maxillectomy.

Tae Kyung CHA ; Ju Hun SONG ; Jee Hye WEE ; Jae Goo KANG

Korean Journal of Otolaryngology - Head and Neck Surgery.2014;57(12):874-878. doi:10.3342/kjorl-hns.2014.57.12.874

Although inverted papilloma (IP) of the nose and paranasal sinus is a benign neoplasm, it is associated with frequent recurrence and malignant transformation. Various surgical techniques have been employed for resection of this tumor. Transnasal endoscopic medial maxillectomy (TEMM) is an effective surgical management of IP originating from the maxillary sinus. It usually removes the inferior turbinate, lateral wall of the nasal cavity, and nasolacrimal duct, and may cause adverse effects such as atrophic rhinitis, empty nose syndrome, impairment of nasal physiological function, and epiphora. Recently, however, a modified TEMM, which preserves the inferior turbinate, lateral wall of the nasal cavity, and nasolacrimal duct has been introduced. We present two cases of IP successfully treated by the modified TEMM.
Endoscopy ; Lacrimal Apparatus Diseases ; Maxillary Sinus* ; Nasal Cavity ; Nasolacrimal Duct ; Nose ; Papilloma, Inverted* ; Recurrence ; Rhinitis, Atrophic ; Turbinates

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A Case of Churg-Strauss Syndrome Involving Nasal Cavity.

Chul Soon JANG ; Dong Wook LEE ; Mi Sook CHOI ; Woo Sub SHIM

Korean Journal of Otolaryngology - Head and Neck Surgery.2014;57(12):870-873. doi:10.3342/kjorl-hns.2014.57.12.870

Churg-Strauss syndrome is a rare systemic vasculitis occurring in patients with asthma and peripheral eosinophilia. Lungs, skin, and the nervous system are the most common sites of involvement, although many other organs are affected frequently. We report a case of 54-year-old male with a history of asthma and chronic rhinosinusitis who was admitted to the emergency department because of dyspnea and pleural pain. He was diagnosed with Churg-Strauss syndrome based on bronchial asthma, peripheral eosinophilia, pulmonary infiltration, chronic rhinosinusitis, and extravascular eosinophil infiltration. His symptoms were resolved dramatically after treatment with corticosteroids. Allergic rhinitis and chronic rhinosinusitis with or without polyps may be present at the early stage of Churg-Strauss syndrome. Therefore, otolaryngologists may play a pivotal role in making an early diagnosis of this disease.
Adrenal Cortex Hormones ; Asthma ; Churg-Strauss Syndrome* ; Dyspnea ; Early Diagnosis ; Emergency Service, Hospital ; Eosinophilia ; Eosinophils ; Humans ; Lung ; Male ; Middle Aged ; Nasal Cavity* ; Nervous System ; Polyps ; Pulmonary Eosinophilia ; Rhinitis ; Skin ; Systemic Vasculitis ; Vasculitis

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Establishment of Cisplatin Resistant Head and Neck Cancer Cell Lines and Cross-resistance of Docetaxel.

Kyong Myong CHON ; Soo Geun WANG ; Byung Joo LEE ; Jin Choon LEE ; Hyoung Joon KOO ; Sun He KIM

Korean Journal of Otolaryngology - Head and Neck Surgery.2005;48(5):651-655.

BACKGROUND AND OBJECTIVES: Treatment of head and neck cancer with cisplatin-based combination chemotherapy has yielded increased complete response rates. In spite of the initial good response, recurrent cancer after chemotherapy does not respond to cisplatin based chemotherapy. In recent years, the analogues of taxol have used in a new chemotherapy treatments for head and neck cancer. The purpose of this study was to develop the acquired resistance to cisplatin in head and neck cancer cell line and to study the cross-resistance of docetaxel and 5-fluorouracil (5-FU) as compared to the parental cells in vitro. SUBJECTS AND METHOD: Two different human head and neck cancer cell lines (PNUH-12, SNU-899) were studied. We developed two cisplatin resistant cell lines (PNUH-12 R1, SNU-899 R1) by exposing them to near continuous increasing concentration of cisplatin. The morphology, growth curve of resistant cell lines were studied and the resistance of these cell lines to the cisplatin, docetaxel and 5-FU were compared to that of parental cells by MTT assay. RESULTS: The pattern of growth and shape of PNUH-12 R1 and SNU 899 R1 cell lines showed similarity to their parent cell lines. The growth curve of these cell lines were suppressed when compared with the parental cells. When compared to the parental cells, PNUH-12 R1 cells were 2.0-fold, 3.8-fold, and 1.4-fold resistant, and SNU 899 R1 cells 3.5-fold, 6.7-fold, and 15.0-fold resistant to cisplatin, docetaxel and 5-FU, respectively. CONCLUSION: In our study, cisplatin resistant cell lines of head and neck cancer have strong cross-resistance to docetaxel. However, there was difference in cross-resistance to 5-FU between these cell lines.
Cell Line* ; Cisplatin* ; Drug Therapy ; Drug Therapy, Combination ; Fluorouracil ; Head and Neck Neoplasms* ; Head* ; Humans ; Paclitaxel ; Parents

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A Clinical Study and Treatment of the Cysts on Epiglottis, Vallecula, and Tongue Base.

Joon Kyoo LEE

Korean Journal of Otolaryngology - Head and Neck Surgery.2005;48(5):656-659.

BACKGROUND AND OBJECTIVES: Cysts on the epiglottis, vallecula, and tongue base are relatively common and usually need surgery with laser under the adjustable laryngoscope. The present study was performed to evaluate the clinical outcome and usefulness of an adjustable laryngoscope and a customized electrocautery. SUBJECTS AND METHOD: Retrospective study was performed in 41 patients with cysts on epiglottis, vallecula, and tongue base and we analyzed the clinical characteristics and treatment outcome by using an adjustable laryngoscopic surgery. RESULTS: There were 33 cases of epiglottic cyst, 4 cases of vallecular cyst, and 4 cases of tongue base cyst. Histopathologic results revealed 34 epithelial cysts and 3 tonsillar cysts. Of 4 tongue base cysts, 2 cases were thyroglossal duct cysts. Excision was done in 35 cases and marsupialization in 6 cases. The adjustable laryngoscope offered a good surgical view on the lingual surface of epiglottis and vallecula but revealed limitations for the tongue base; the customized electrocautery did not cause significant surgical problems or tissue damage. Seven patients had persistent symptoms such as those of gastroesophageal reflux after surgery. Recurrence was observed in 2 cases at 5 months following the operation and at 3 1/2 years, respectively. CONCLUSION: Cysts on the epiglottis, vallecula, and tongue base were successfully operated with a customized electrocautery under the adjustable laryngoscope. Patients with vague symptoms such as those of gastroesophageal reflux need to be carefully selected for the surgery and long-term follow-up is required for recurrence.
Electrocoagulation ; Epiglottis* ; Follow-Up Studies ; Gastroesophageal Reflux ; Humans ; Laryngoscopes ; Laryngoscopy ; Recurrence ; Retrospective Studies ; Thyroglossal Cyst ; Tongue* ; Treatment Outcome

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Voice Analysis after the Vertical Partial Laryngectomy.

Chul Ho KIM ; Sang Ho JUNG ; Joong Wook SHIN ; Young Ho KIM ; Hong Sik CHOI ; Kwang Moon KIM ; Eun Chang CHOI

Korean Journal of Otolaryngology - Head and Neck Surgery.2003;46(5):414-418.

BACKGROUND AND OBJECTIVES: It is generally believed that reconstruction of the glottic region after vertical partial laryngectomy (VPL) can improve glottic and supraglottic function. But reports on secondary healing without glottic reconstruction after VPL are lacking. This study attempts to obtain an objective phonatory data after VPL without glottic reconstruction. MATERIALS AND METHODS: From 1993 to 2001, 13 patients, who had been treated with VPL without glottic reconstruction, and 44 patients who underwent VPL were included in this study. Patients who had been followed up postoperatively less than 12 months were excluded from this study. Seven lesions were classified as T1 glottic cancer and six as T2 glottic cancer ; classic VPL (11 cases) and frontolateral VPL (2 cases). For the evaluation of voice, acoustic (fundamental frequency (Fo), jitter, shimmer, noise to harmonic ratio (NHR)), aerodynamic (maximal phonation time (MPT), mean flow rate (MFR)) analysis and videostroboscopy were done. RESULTS: There were significant differences in Fo, jitter, shimmer, NHR, MPT and MFR between VPL group and the normal control group. In videostroboscopy, the following tendencies were observed in many cases: incopmplete glottic closure, decreased and irregular mucosal wave and amplitude, supraglottic voicing, abnormal arytenoid movement and anterior commissure blunting. CONCLUSION: We had objective phonatory data after VPL without glottic reconstruction, which showed that voice quality after VPL without glottic reconstruction were somewhat unsatisfactory. Further studies on other surgical techniques of VPL would help to elucidate better ways of improving voice quality in these patients.
Acoustics ; Humans ; Laryngectomy* ; Noise ; Phonation ; Voice Quality ; Voice*

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Sclerosing Mucoepidermoid Carcinoma in the Parotid Gland: Literature Review.

Chang Ki WOO ; Bae Hyun KIM ; Byung Joo LEE ; Jin Choon LEE

Korean Journal of Otolaryngology - Head and Neck Surgery.2012;55(8):508-512. doi:10.3342/kjorl-hns.2012.55.8.508

Mucoepidermoid carcinoma is the most common malignant salivary gland neoplasm. Its sclerosing morphologic variant, however, is an extremely rare entity. Only 15 cases have been reported in the English literature. We report a case of a sclerosing mucoepidermoid carcinoma in the left parotid gland with a review of literature. A fifty seven-year-old female patient presented with left parotid mass. Fine needle aspiration biopsy reported a parotid gland tumor, predominantly benign cystic condition, and the differential diagnosis included benign lymphoepithelial cyst and Warthin' tumor. Left superficial parotidectomy was performed. Histologically, a well demarcated mass (2.2x1.5x1.0 cm) was composed of a central sclerosis with a few tumor nests and a peripheral lymphoid hyperplasia. The lumen of the tumor glands is filled with mucin stained with mucicarmine. Finally, it was diagnosed as sclerosing mucoepidermoid carcinoma.
Biopsy ; Biopsy, Fine-Needle ; Carcinoma, Mucoepidermoid ; Carmine ; Diagnosis, Differential ; Female ; Humans ; Hyperplasia ; Mucins ; Parotid Gland ; Salivary Gland Neoplasms ; Sclerosis

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