Journal Detail Information

1

Cite

Share

Clinical and Electrophysiological Changes after Open Carpal Tunnel Release: Preliminary Study of 25 Hands.

Ji Won YANG ; Young Hee SUNG ; Kee Hyung PARK ; Yeong Bae LEE ; Dong Jin SHIN ; Hyeon Mi PARK

Korean Journal of Clinical Neurophysiology.2014;16(1):21-26. doi:10.14253/kjcn.2014.16.1.21

BACKGROUND: Electrophysiological study has been known as a useful method to evaluate the therapeutic effect of operation in idiopathic carpal tunnel syndrome (CTS). The purpose of this study was to evaluate the clinical and electrophysiological changes after carpal tunnel release (CTR) compared to the preoperative results. METHODS: We analyzed the changes of nerve conduction study (NCS) before and after minimal open carpal tunnel release in 18 patients (25 hands) with CTS. Follow-up study was performed over 6 months after operation. RESULTS: Clinical improvement was seen in all cases after CTR. In contrast, electrophysiological improvement was various depending on the parameters; the mean median sensory latency and nerve conduction velocity (NCV) improved significantly (p = 0.001). The mean median motor latency also improved, but NCV and compound muscle action potential (CMAP) amplitude did not change. The extent of improvement was evident in moderate CTS, but not in severe CTS. CONCLUSIONS: In this preliminary study, all subjects who underwent CTR achieved a clinical relief along with a significant improvement of electrophysiological parameters such as median sensory latency, sensory NCV and median distal motor latency. After CTR, a number of cases with mild to moderate CTS showed a prominent improvement of clinical and electrophysiological parameters, while fewer improvements were seen in severe CTS, although it did not reach the statistical significance.
Action Potentials ; Carpal Tunnel Syndrome ; Electrophysiology ; Follow-Up Studies ; Hand* ; Humans ; Median Nerve ; Neural Conduction

2

Cite

Share

Significance of Triphasic Waves in Metabolic Encephalopathy.

Kang Min PARK ; Kyong Jin SHIN ; Sam Yeol HA ; Jinse PARK ; Si Eun KIM ; Hyung Chan KIM ; Sung Eun KIM

Korean Journal of Clinical Neurophysiology.2014;16(1):15-20. doi:10.14253/kjcn.2014.16.1.15

BACKGROUND: Triphasic waves are one of the electroencephalographic patterns that can be usually seen in metabolic encephalopathy. The aim of this study is to compare the clinical and electrophysiologic profiles between patients with and without triphasic waves in metabolic encephalopathy, and reassess the significance of triphasic waves in metabolic encephalopathy. METHODS: We recruited 127 patients with metabolic encephalopathy, who were admitted to our hospital. We divided these admitted patients into two groups; those with and without triphasic waves. We analyzed the difference of duration of hospitalization, mortality rate during admission, Glasgow Coma Scale, severity of electroencephalographic alteration, and presence of acute symptomatic seizures between these two groups. RESULTS: Of the 127 patients with metabolic encephalopathy, we excluded 67 patients who did not have EEG, and 60 patients finally met the inclusion criteria for this study. Patients with triphasic waves had more severe electroencephalographic alterations, lower Glasgow Coma Scale, and more acute symptomatic seizures than those without triphasic waves. After adjusting the clinical variables, Glasgow Coma Scale and acute symptomatic seizures were only significantly different between patients with and without triphasic waves. CONCLUSIONS: We demonstrated that patients with triphasic waves in metabolic encephalopathy had more significant impairment of the brain function.
Brain ; Brain Diseases, Metabolic* ; Electroencephalography ; Glasgow Coma Scale ; Hospitalization ; Humans ; Metabolism ; Mortality ; Seizures

3

Cite

Share

Peripheral Nerve Abnormalities in Patients with Newly Diagnosed Type I and II Diabetes Mellitus.

Sang Soo LEE ; Heon Seok HAN ; Heon KIM

Korean Journal of Clinical Neurophysiology.2014;16(1):8-14. doi:10.14253/kjcn.2014.16.1.8

BACKGROUND: Early detection of neuropathy may prevent further progression of this complication in the diabetic patients. The purpose of this study was to evaluate the prevalence of early neuropathic complication in patients with newly diagnosed type 1 and type 2 diabetes. METHODS: Nerve conduction studies (median, ulnar, posterior tibial, peroneal, and sural nerves) were performed for 49 type 1 (27 males, mean 14.1+/-7.5 years) and 40 type 2 (27 males, 42.0+/-14.1 years) diabetic patients at onset of diabetes. Children with age at onset under 4 years and adults over 55 years were excluded to eliminate the aging effect and the influence of obstructive arteriosclerosis. Neuropathy was defined as abnormal nerve conduction findings in two or more nerves including the sural nerve. RESULTS: Mean HbA1c level was 12.6+/-3.3% for type 1 and 10.5+/-2.9% for type 2 diabetes. The prevalence of neuropathy was 12.2% for type 1, and 35.0% for type 2 diabetes, respectively. There were significant trends in the prevalence of neuropathy with increasing age (p<0.05). The effect of the mean level of glycosylated hemoglobin on the prevalence of polyneuropathy at onset of diabetes was borderline (p=0.0532). Neither sex of the patients nor the type of diabetes affected the neurophysiologic abnormalities at the diagnosis. CONCLUSIONS: Even in a population with diabetes at the diagnosis, the prevalence of subclinical neuropathy was not low. Neuropathy has been significantly associated with increasing age indicating the possibility of longer duration of undetected diabetes among them, especially in type 2 diabetes.
Adult ; Aging ; Arteriosclerosis ; Child ; Diabetes Mellitus* ; Diabetic Neuropathies ; Diagnosis ; Hemoglobin A, Glycosylated ; Humans ; Male ; Neural Conduction ; Peripheral Nerves* ; Polyneuropathies ; Prevalence ; Sural Nerve

4

Cite

Share

Application of Iron Related Magnetic Resonance Imaging in the Neurological Disorders.

Tae Hyoung KIM ; Jae Hyeok LEE

Korean Journal of Clinical Neurophysiology.2014;16(1):1-7. doi:10.14253/kjcn.2014.16.1.1

Iron is an important element for brain oxygen transport, myelination, DNA synthesis and neurotransmission. However, excessive iron can generate reactive oxygen species and contribute neurotoxicity. Although brain iron deposition is the natural process with normal aging, excessive iron accumulation is also observed in various neurological disorders such as neurodegeneration with brain iron accumulation, Parkinson's disease, Alzheimer's disease, multiple sclerosis, Friedreich ataxia, and others. Magnetic resonance image (MRI) is a useful method for detecting iron deposits in the brain. It can be a powerful tool for diagnosis and monitoring, while furthering our understanding of the role of iron in the pathophysiology of a disease. In this review, we will introduce the mechanism of iron toxicity and the basics of several iron-related MRI techniques. Also, we will summarize the previous results concerning the clinical application of such MR imagings in various neurological disorders.
Aging ; Alzheimer Disease ; Brain ; Diagnosis ; DNA ; Friedreich Ataxia ; Iron* ; Magnetic Resonance Imaging* ; Multiple Sclerosis ; Myelin Sheath ; Nervous System Diseases* ; Neurodegenerative Diseases ; Oxygen ; Parkinson Disease ; Reactive Oxygen Species ; Synaptic Transmission

5

Cite

Share

Asymptomatic HyperCKemia Presenting as a Sole Manifestation of Hypothyroidism.

Sun Woo PARK ; Hong Jun KIM ; Sa Yoon KANG

Korean Journal of Clinical Neurophysiology.2014;16(1):45-47. doi:10.14253/kjcn.2014.16.1.45

No abstract available.
Creatine Kinase ; Hypothyroidism* ; Muscular Diseases

6

Cite

Share

Vagus Nerve Palsy in Ramsay-Hunt Syndrome.

Sang Bub LEE ; Dong Kuck LEE

Korean Journal of Clinical Neurophysiology.2014;16(1):42-44. doi:10.14253/kjcn.2014.16.1.42

No abstract available.
Paralysis* ; Vagus Nerve*

7

Cite

Share

Anatomical Findings of Hemiplegia Cruciata in Multiple Sclerosis.

Hye Young JEONG ; Eun Joo CHUNG ; Eung Gyu KIM ; Jong Seok BAE

Korean Journal of Clinical Neurophysiology.2014;16(1):39-41. doi:10.14253/kjcn.2014.16.1.39

Hemiplegia cruciata (HC) manifests as paralysis of the ipsilateral arm and contralateral leg. Herein, we report a 64-year-old man with weakness of the right leg and of the left arm after multiple sclerosis (MS). His brain and spine magnetic resonance imaging show a lower medulla lesion, which is extended to posterior part of C1 spine through cervicomedullary junction. HC usually results from stroke or trauma, but it is rare as presenting symptom of MS.
Arm ; Brain ; Hemiplegia* ; Humans ; Leg ; Magnetic Resonance Imaging ; Middle Aged ; Multiple Sclerosis* ; Paralysis ; Pyramidal Tracts ; Rubiaceae* ; Spine ; Stroke

8

Cite

Share

Japanese-B Viral Encephalitis with a Biphasic Illness Pattern and Recovery after Intravenous Immunoglobulin Therapy.

Byung Chan LEE ; Ji Ye JEON ; Hye Jin MOON ; Jeong Geun LIM ; Yong Won CHO

Korean Journal of Clinical Neurophysiology.2014;16(1):35-38. doi:10.14253/kjcn.2014.16.1.35

Japanese-B viral encephalitis (JE) usually has a monophasic illness pattern. A 45-year-old woman in an altered mentality had improved over 1 month. About 1 week after the initial improvement, the patient became comatose with aggravated EEG and MRI findings. Assays of cerebrospinal fluid and serum were positive for the IgM antibody to Japanese-B virus. After intravenous immunoglobulin (IVIG) infusion, the patient recovered. We report a patient with JE who showed a biphasic illness pattern and recovered after IVIG therapy.
Cerebrospinal Fluid ; Coma ; Electroencephalography ; Encephalitis, Viral* ; Female ; Humans ; Immunization, Passive* ; Immunoglobulin M ; Immunoglobulins ; Immunoglobulins, Intravenous ; Magnetic Resonance Imaging ; Middle Aged

9

Cite

Share

Rotational Vertigo and Unsteady Gait Associated with Vestibular Cortical Infarction.

Kang Min PARK ; Sung Eun KIM ; Kyong Jin SHIN ; Jin Se PARK ; Si Eun KIM ; Hyung Chan KIM ; Sam Yeol HA

Korean Journal of Clinical Neurophysiology.2014;16(1):32-34. doi:10.14253/kjcn.2014.16.1.32

A 77-year-old man developed acute vertigo and unsteady gait. Neurological examination revealed spontaneous left-beating nystagmus in the primary position. He fell to the left when walking without support. Magnetic resonance imaging showed an acute infarction involving the right parieto-temporal lobe. Although the vertigo and unsteady gait are most often associated with vestibular disorders involving the infratentorial structures, those may occur in cerebral infarction of the parieto-temporal lobe.
Aged ; Cerebral Infarction ; Gait Disorders, Neurologic* ; Humans ; Infarction* ; Magnetic Resonance Imaging ; Neurologic Examination ; Stroke ; Vertigo* ; Walking

10

Cite

Share

A Case of Wernicke's Encephalopathy Presenting as Acute Bilateral Wrist Drop.

Do Hyung KIM ; Sun Young OH

Korean Journal of Clinical Neurophysiology.2014;16(1):27-31. doi:10.14253/kjcn.2014.16.1.27

Thiamine deficiency can cause peripheral polyneuropathy and Wernicke's encephalopathy. Wernicke's encephalopathy is characterized by ataxia, ophthalmoplegia, nystagmus, and confusion, and typically presents acute and rapidly progressive course, whereas peripheral neuropathy associated with thiamine deficiency manifests chronic and slowly progressive one. However, acute and rapidly progressive axonal polyneuropathy combined with Wernicke's encephalopathy is quite rare and unusual. Here, we describe a patient with Wernicke's encephalopathy who presented with acute bilateral axonal neuropathy.
Ataxia ; Axons ; Humans ; Ophthalmoplegia ; Peripheral Nervous System Diseases ; Polyneuropathies ; Thiamine ; Thiamine Deficiency ; Wernicke Encephalopathy* ; Wrist*

DISPLAY OPTIONS

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share