Journal Detail Information

1

Cite

Share

Miyalisan Compared with Ribavirin in the Treatment of Infan ts'Diarrhea

Herald of Medicine.2001;(4):228-. doi:10.3870/j.issn.1004-0781.2001.04.016

To compare the efficacy on miyalisa n with ribavirin in the treatment of infants' diarrhea. Methods: 152 infants with diarrhea in outpatient department were divided into two groups treated with miyalisan (80 cases) or ribavirin (72 cases) for 3 days. The therapy could be continued for another 3 days if necessary. Results : The Clinically effective rate and the negative conversion rate of rotavirus in the treated group and controlled group were 93.8% and 87%, 82% and 60%, respectively, there were sinnificantly different(P＜0.05) between two g roups. Conclusion: Miyalisan had showed a better efficacy in treatment of infants' rotavivus enteritis than ribavirin.

2

Cite

Share

General Anaesthesia Induced with Disoprivan Combined with Eph edrine in 15 Cases of Elder Patients

Yuli JI

Herald of Medicine.2001;(4):215-. doi:10.3870/j.issn.1004-0781.2001.04.004

irty elder patients above 65 years were randomly divided into two groups. group I induced with disoprivan 1.5 mg·kg-1and group Ⅱ induced with disoprivan 1.5 mg·kg-1 combined with ephedrine 0.075 mg·kg-1Changes of systolic pressure, diastolic pressure, heart rate, ECG, SpO2 wer eabserved. Every their base values before induction every determining ralues, after induction, and after tracheal intubatton were controlled and statistical an alyzed. Results: Each value after induction and after tra cheal intubatton were lower than their base value (P＜0.05) in two groups, respectirely. The declining ranges of SBP, DBP, HR after induction and after trac heal intubatton in group Ⅱ were lower than that in group Ⅰ, there was a signif icant difference between both groups (P＜0.05). Conclusion:There is a certain using importance that general anaesthesia induced with disoprivan combined with ephedrine 0.075 mg·kg-1to be used for elder patients.

3

Cite

Share

Effects of Ozone Solution on the Healing and Antiinfection of TraumaticWound

Shengzhou YOU ; YongPeng WAN

Herald of Medicine.2001;(4):213-. doi:10.3870/j.issn.1004-0781.2001.04.002

To evaluate the effects of ozone so lution on the healing and antiinfection of traumatic wound. Methods :300 patients with traumatic wounds were washed with ozone solution. Under the direction of ozone generator handbook, the ozone solution of which con centration was not less than 6 mg·L-1was prepared. The solution was used for the traumatic wound by atomized or beam spraying. The healing conditions of the wounds were observed and recorded the 3,5,7 days after debridement. Results:In the experimental group, there were 142 cases (87.6% ) with first grade intention, 16 cases (9.9%) with second grade intention, and 4 cases (2.5%) with the third grade intention. On the contrast, there were 76.8%, 17.3% and 5.8%, respectively, in the controlled group. There was avery signific anty difference between both experimental groups (P＜0.05).Concl usion: Ozone solution is a safe, cheap, high efficient disinfectant agent, used widely in the traumatic surgery and other fields for disinfection or sterilization.

4

Cite

Share

Experimental Research and Clinical Observation of Circadian R hythm on Pharmacodynamics of Lidocain Alkalified Solution

Dunyi HU ; Hui WANG

Herald of Medicine.2001;(4):261-. doi:10.3870/j.issn.1004-0781.2001.04.049

To explore the time-dependent of p harmacodynamics of lidocain alkalified solution. Method: On 8:00 am and 8:00 pm, surface anaesthesia and subarachnoid anaesthesia were con ducted in rabbits and 76 cases of surgical patients receiving epidureal anaesthe sia were observed in therapy effect.Results: The results of animal experimental showed the anaesthesia potency and anaesthesia incubatory period were better on 8:00 am than 8:00 pm; the clinical observation also obtain ed asimilar result. Conclusion: These results showed that lidocain alkalified solution had time-dependent of pharmacodynamics.

5

Cite

Share

Clinical Study of Ginkgobiloba Extract in the Treatment of Epilepsy

Haojun YIN ; Zhiyi GUO

Herald of Medicine.2001;(2):98-. doi:10.3870/j.issn.1004-0781.2001.02.014

Objective:To study the clinical value of ginkgobiloba extract in the treatment of epilepsy.Method:68 patients were divided into two groups,the control group and the treatment group. The patients in the control group were treated with sodium phenytoin,tegretol,or diazepam. In the treatment group,ginkgobiloba extract was given in addition to the antiepilepsy drugs used in the former group.Results:In the treatment group,the total effective rate were significantly higher than that of the control group (P＜0.05).Conclusion:Ginkgobiloba extract was a safe and effective addition to the pool of antiepilepsy drugs.

6

Cite

Share

The Effects of β-aescinum Natrium in 58 Patients with Cerebral Infarction

Riying AO

Herald of Medicine.2001;(2):103-. doi:10.3870/j.issn.1004-0781.2001.02.019

Objective:To explore the effects of β-aescinum natrium in treating patient with cerebral infarction.Methods:All patients were randomly divided into two group:treatment group (58 cases) and control group. The results were compared between the two groups.Results:In treatment group of 58 cases,healing rate is significant higher than that of the control group (P＜0.01),and so is the total effective rate (P＜0.05).Conclusion:This drug has some good virtues,such as less side effects,faster response and easy to use as well as no irritation to vein when given intravenously. So,it has better clinic value in the treatment of acute cerebral infarction.

7

Cite

Share

Effect of Atorvastatin on Carotid Artery Atherosclerotic Plaque

Wei CUI ; Limin ZANG ; Longan WANG

Herald of Medicine.2014;(6):752-754. doi:10.3870/yydb.2014.06.017

Objective To evaluate the effect of atorvastatin on human carotid plaque by high resolution nuclear magnetic resonance imaging(MRI 3. 0T). Methods Forty patients with carotid artery plaque were treated with atorvastatin at the dose of 20 mg daily for one year. Changes of the artery plaques were observed by MRI,and the levels of blood lipoproteins and C reactive protein( hs-CRP)were detected. Results After the treatment with atorvastatin for 6 months and 1 year,the number and average thickness of plaques were reduced. One year after the treatment,average thickness of stable plaques dropped from (2. 41±0. 54)mm to(2. 17±0. 49)mm,and the size of the unstable plaques decreased from(2. 38±0. 89)mm to(2. 01± 0. 32)mm,with significant differences(P﹤0. 05). The levels of TC,TG,LDL-C and Hs-CRP were significantly decreased(P﹤0. 05)and the level of HDL-C was increased. Conclusion High resolution nuclear magnetic resonance( MRI3. 0T)can clearly display the components of the atherosclerotic plaque and the degree of artery stenosis. Atorvastatin exerts a significant effect on carotid plaque by promoting the regression of the carotid atherosclerosis plaque.

8

Cite

Share

Association of ERCC1 and BRCA1 Expression with Clinical and Pathological Features and Sensitivity to Platinum-containing Adjuvant Chemotherapy in Patients with Ovarian Epithelial Carcinoma

Pei DU ; Yifeng WANG ; Xiaowei ZHANG ; Liquan CHEN ; Guoqin CHEN

Herald of Medicine.2014;(6):747-751. doi:10.3870/yydb.2014.06.016

Objective To investigate the association of ERCC1 and BRCA1 gene expression with clinical features and sensitivity to platinum-containing chemotherapy in patients with ovarian epithelial carcinoma. Methods Primary ovarian epithelial carcinoma tissues were harvested from 48 patients receiving staging surgery or cytoreductive surgery. Expression of ERCC1 and BRCA1 in the tumor samples was detected by immunohistochemistry. Results ERCC1 expression was correlated with clinical stage(P﹤0. 05)but not with age,pathological type or degree of differentiation(P﹥0. 05). BRCA1 expression was not correlated with any of the clinicopathological features(P﹥0. 05);ERCC1 expression was significantly higher in drug-resistant tissues than in drug-sensitive samples(P﹤0. 05);The expression of ERCC1 and BRCA1 was positive in 89. 58%and 25. 00%of the samples,respectively. Conclusion ERCC1 gene expression is correlated with clinical stage but not with age,pathological type or degree of differentiation. BRCA1 gene expression is not correlated with clinicopathological features. ERCC1 has high positive expression in epithelial ovarian cancer and is correlated with sensitivity of platinum-containing adjuvant chemotherapy.

9

Cite

Share

Optimal Rectal Dosage of Misoprostol for Dilation of Cervix Before Painless Electrical Vacuum Abortions

Ming TONG ; Ying CHEN ; Jing WANG

Herald of Medicine.2014;(6):733-735. doi:10.3870/yydb.2014.06.011

Objective To evaluate the optimal dosage of misoprostol administered in the rectum for dilation of the cervix. Methods Two hundred and forty women at 40-60 day gestational age without vaginal delivery history were randomly divided into three groups,with 80 cases in each group. Patients received 200,400 or 600μg of misoprostol rectally one hour before electrical vacuum abortions in group A,B and C,respectively. Cervical dilation,blood loss,and drug side effects in the three groups were compared. Venous blood samples were taken before vein anesthesia,and misoprostol acid concentration in the serum was tested by liquid chromatography-mass spectrometry. Results The analgesic rate was 100. 00%in all three dose groups, and cervical dilation rate was 23. 75%,46. 25%and 70. 00%in groups A,B and C,respectively. The severity of drug side effects such as vaginal bleeding and abdominal pain is dose-dependent. Blood concentration of misoprostal acid was(117±65),(206± 98),and(303±149)pg·mL-1 ,in groups A,B and C,respectively. Conclusion The recommended dose of misoprostol is 400 μg administered in rectum. Rectal administration of misoprostol is cheap,safe,and convenient,and therefore could be widely applied.

10

Cite

Share

Inhibition of Extract from Leaf of Stellera chamaijasme L on Dermatic Staphylococcus aureus and Trichophyton gypseum

Renjun TIAN

Herald of Medicine.2014;(6):729-732. doi:10.3870/yydb.2014.06.010

Objective To study the antibiotic activities of leaf extract of Stellera chamaejasme L on the skin. Methods Activities of the leaf extract on Trichophyton gypseum and Staphylococcus aureus was examined by antibiotic susceptibility paper disk method and tube double dilution method. Results When extracted by 95%ethanol,the extract from Stellera chamaejasme L at 100 mg·mL-1 formed an inhibition zone with the diameter of 12. 8 mm for Staphylococcus aureus and 12. 0 mm for Trichophyton gypseum. When extracted by dichloromethane,the minimum inhibitory concentration( MIC)of the extract from Stellera chamaejasme L was 0. 25 mg·mL-1 for Staphylococcus aureus and 0. 50 mg·mL-1 for Trichophyton gypsem.
Conclusion Leaf extract of Stellera chamaejasme L has an antibacterial activity against Staphylococcus aureus and Trichophyton gypseum and the antibacterial activity against Staphylococcus aureus is stronger.

DISPLAY OPTIONS

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share