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Tuberculosis and Respiratory Diseases

  to  Present  ISSN: 1738-3536

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Thirty six-year-old man presenting acute respiratory failure.

Tae Rim SHIN ; Ji Eun JANG ; Hae Young KIM ; Young Sik PARK ; Woon Sup HAN ; Jung Hyun CHANG

Tuberculosis and Respiratory Diseases.2000;49(4):514-519. doi:10.4046/trd.2000.49.4.514

We report a case of pneumonia in 36 year-old male patient who presented acute respiratory failure and associated radiologic findings of bilateral ground-glass opacity with focal cystic changes, showing rapidly aggravating course and was diagnosed as concomitant Pneumocystis carinii and Cytomegalovirus pneumonia accompanied by acquired immunodeficiency syndrome through antemortem open lung biopsy.
Acquired Immunodeficiency Syndrome ; Biopsy ; Cytomegalovirus ; Humans ; Lung ; Male ; Pneumocystis carinii ; Pneumonia ; Respiratory Insufficiency*

Acquired Immunodeficiency Syndrome ; Biopsy ; Cytomegalovirus ; Humans ; Lung ; Male ; Pneumocystis carinii ; Pneumonia ; Respiratory Insufficiency*

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A Case of aspergillus tracheobronchitis in non-immunocompromise patient.

Hyo Young CHUNG ; Hwi Jong KIM ; Soo Hee KIM ; Jong Deog LEE ; Young Sil HWANG

Tuberculosis and Respiratory Diseases.2000;49(4):508-513. doi:10.4046/trd.2000.49.4.508

The aspergillus tracheobronchitis is distinctive manifestation of invasive aspergillosis, in which infection is limited completely or predominantly to the tracheobronchial tree. It accounts for about 7 to 10 percent of cases of invasive disease. Grossly, such disease may take the mucosal exudate and obstruct partially the airway lumen or completely the occlusive mucous/fungus plugs. Microscopically, the superficial portion of the airway wall is acutely inflamed and contain fungal hyphae. However, infection is often limited to the mucosa. We report a case of aspergillus tracheobrochits in a 54 year-old man who presented cough, progressive dyspnea with wheezing, and mucus plug. Bronchoscopy showed mucosal exudate and plug.Bronchoscopic biopsy showed aspergillus hyphae and inflammation in the mucosa. He was successfully treated with itraconazole.
Aspergillosis ; Aspergillus* ; Biopsy ; Bronchoscopy ; Cough ; Dyspnea ; Exudates and Transudates ; Humans ; Hyphae ; Inflammation ; Itraconazole ; Mucous Membrane ; Mucus ; Respiratory Sounds ; Trees

Aspergillosis ; Aspergillus* ; Biopsy ; Bronchoscopy ; Cough ; Dyspnea ; Exudates and Transudates ; Humans ; Hyphae ; Inflammation ; Itraconazole ; Mucous Membrane ; Mucus ; Respiratory Sounds ; Trees

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Interstitial Lung Diseases: Respiratory Review of 2013.

Yong Hyun KIM ; Soon Seog KWON

Tuberculosis and Respiratory Diseases.2013;75(2):47-51. doi:10.4046/trd.2013.75.2.47

Interstitial lung diseases are heterogeneous entities with diverse clinical presentations. Among them, idiopathic pulmonary fibrosis and connective tissue disease-associated interstitial lung disease are specific categories that pulmonologists are most likely to encounter in the clinical field. Despite the accumulated data from extensive clinical trial and observations, we continue to have many issues which need to be resolved in this field. In this update, we present the review of several articles regarding the clinical presentation, prognosis and treatment of patients with idiopathic pulmonary fibrosis or connective tissue disease-associated interstitial lung disease.
Connective Tissue ; Connective Tissue Diseases ; Humans ; Idiopathic Pulmonary Fibrosis ; Lung ; Lung Diseases, Interstitial ; Prognosis

Connective Tissue ; Connective Tissue Diseases ; Humans ; Idiopathic Pulmonary Fibrosis ; Lung ; Lung Diseases, Interstitial ; Prognosis

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Two cases of Pulmonary Alveolar Proteinosis Improved by Whole Lung Lavage.

Seong Su JEONG ; Dong Won KANG ; Kyu Seung LEE ; Dong Seok KO ; Jae Chul SUH ; Keun Hwa KIM ; Jin Whan KIM ; Jung Un LEE ; Ju Ock KIM ; Sun Young KIM

Tuberculosis and Respiratory Diseases.1999;47(3):406-413. doi:10.4046/trd.1999.47.3.406

Pulmonary alveolar proteinosis(PAP) is a disorder in which an insoluble, proteinaceous material, rich in phospholipid, is deposited on alveoli and bronchioles. Several cases were reported since 1986, and the numbers of patients is increasing in Korea. Although the pathogenesis and causative treatment of PAP is not well known, whole lung lavage is the only consistently successful treatment. We report 2 cases of PAP which were confirmed by open lung biopsy with electron microscopy and clinically improved by whole lung lavage with a review of literature.
Biopsy ; Bronchioles ; Bronchoalveolar Lavage* ; Humans ; Korea ; Lung* ; Microscopy, Electron ; Pulmonary Alveolar Proteinosis*

Biopsy ; Bronchioles ; Bronchoalveolar Lavage* ; Humans ; Korea ; Lung* ; Microscopy, Electron ; Pulmonary Alveolar Proteinosis*

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Spontaneous Rupture of Mediastinal Teratoma into Adjacent Tissues.

Jeong Bae JEON ; Chung Hwan CHUNG ; Tai Hoon MOON ; Jae Wha CHO ; Jeong Seon RYU ; Seung Min KWAK ; Hong Lyeol LEE ; Chul Ho CHO ; Hye Seung HAN

Tuberculosis and Respiratory Diseases.1999;47(3):400-405. doi:10.4046/trd.1999.47.3.400

Mediastinal teratomas are rare and represent less than 10 per cent of all mediastinal tumors. Almost all arise in the anterosuperior mediastinal compartment, and most symptoms, when present, result from compression of adjacent structures. They contain different tissues derived from all three germinal layers, with the prevalence of ectodermal elements which can include hair, teeth and sebaceous material. Benign teratomas may rupture into adjacent organs. Up to 36% of all mediastinal teratomas rupture, most frequently into the lung and bronchial tree, followed by the pleural space, pericardial space, or great vessels. The signs and symptoms of a ruptured teratoma vary with the structures involved. We report a case of mediastinal teratoma ruptured spontaneously in a 18 year old female who experienced 4 or 5 times of hemoptysis for 1 year and sudden onset of pleural effusion, pericardial effusion and pneumonia.
Adolescent ; Ectoderm ; Female ; Hair ; Hemoptysis ; Humans ; Lung ; Mediastinum ; Pericardial Effusion ; Pleural Effusion ; Pneumonia ; Prevalence ; Rupture ; Rupture, Spontaneous* ; Teratoma* ; Tooth

Adolescent ; Ectoderm ; Female ; Hair ; Hemoptysis ; Humans ; Lung ; Mediastinum ; Pericardial Effusion ; Pleural Effusion ; Pneumonia ; Prevalence ; Rupture ; Rupture, Spontaneous* ; Teratoma* ; Tooth

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A Case of Pulmonary Thromboembolism due to Congenital Antithrombin III Deficiency.

Hyeong Kwan PARK ; Chang Min PARK ; Kyoung Haeng KO ; Myung Soo RIM ; Yu Il KIM ; Jun Hwa HWANG ; Sung Chul LIM ; Young Chul KIM ; Kyung Ok PARK

Tuberculosis and Respiratory Diseases.1999;47(3):394-399. doi:10.4046/trd.1999.47.3.394

We report a case of congenital and familial antithrombin III deficiency developing massive pulmonary thromboembolism. A 44-year-old man was admitted to our hospital because of sudden chest pain and severe dyspnea. Five years ago, he was operated due to a mesenteric vein thrombosis of unknown cause. On admission, radioisotopic venogram showed deep vein thrombosis and lung scintigram showed multiple segmental perfusion defects. His plasma antithrombin III level was 10.5 mg/dL which was less than 50% of normal and those of a son and two daughters were also decreased. After treatment with tissue plasminogen activator, heparin and coumadin, his symptom and lung scintigram were significantly improved. As far as we reviewed, there were very rare reports with congenital antithrombin III deficiency presenting as pulmonary thromboembolism in Korea.
Adult ; Antithrombin III ; Antithrombin III Deficiency* ; Chest Pain ; Dyspnea ; Heparin ; Humans ; Korea ; Lung ; Mesenteric Veins ; Nuclear Family ; Perfusion ; Plasma ; Pulmonary Embolism* ; Thrombosis ; Tissue Plasminogen Activator ; Venous Thrombosis ; Warfarin

Adult ; Antithrombin III ; Antithrombin III Deficiency* ; Chest Pain ; Dyspnea ; Heparin ; Humans ; Korea ; Lung ; Mesenteric Veins ; Nuclear Family ; Perfusion ; Plasma ; Pulmonary Embolism* ; Thrombosis ; Tissue Plasminogen Activator ; Venous Thrombosis ; Warfarin

7

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Pulmonary Endometriosis.

Ki Joong KIM ; Yoon Hyung CHO ; Byeong Kee CHOI ; Eui Young CHOI ; Yoon Su CHANG ; Hyung Jung KIM ; Chul Min AHN ; Sang Ho CHO ; Jin A RHU

Tuberculosis and Respiratory Diseases.1999;47(3):389-393. doi:10.4046/trd.1999.47.3.389

Endometriosis is defined as an extrauterine growth of endometrial tissue and it is primarily limited in the pelvis but it can also occur in the pleural cavity as well as pulmonary parenchyme. The diagnosis of pulmonary endometriosis is usually based on the clinical history of recurrent hemoptysis in association with menstrual cycle and by histopathologic confirmation of endometrial tissue in the lung parenchyme. Pulmonary endometriosis was first reported by Lattes in 1956, and dozens of cases have been reported so far. We experienced a case of 25 year old single woman with a history of hemoptysis in association with her menstruation. The bleeding focus was localized with chest CT scan and repeated fibrooptic bronchoscopy and basal segmentectomy of the right lower lobe was performed. The resected specimen shows endometrial stroma and glands of early proliferative phase with respiratory epithelium on the laterobasal bronchus. Her postoperative course was uneventful with no recurrence of hemoptysis during 6 months of follow-up in the outpatient clinic.
Adult ; Ambulatory Care Facilities ; Bronchi ; Bronchoscopy ; Diagnosis ; Endometriosis* ; Female ; Follow-Up Studies ; Hemoptysis ; Hemorrhage ; Humans ; Lung ; Mastectomy, Segmental ; Menstrual Cycle ; Menstruation ; Pelvis ; Pleural Cavity ; Recurrence ; Respiratory Mucosa ; Tomography, X-Ray Computed

Adult ; Ambulatory Care Facilities ; Bronchi ; Bronchoscopy ; Diagnosis ; Endometriosis* ; Female ; Follow-Up Studies ; Hemoptysis ; Hemorrhage ; Humans ; Lung ; Mastectomy, Segmental ; Menstrual Cycle ; Menstruation ; Pelvis ; Pleural Cavity ; Recurrence ; Respiratory Mucosa ; Tomography, X-Ray Computed

8

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A Case of Tracheal Hamartoma.

Ho Il YOON ; Sang Min LEE ; Seung Ho CHOI ; Bin HWANGBO ; Chul Gyu YOO ; Choon Taek LEE ; Young Whan KIM ; Sook Hwan SUNG ; Sung Koo HAN ; Young Soo SHIM

Tuberculosis and Respiratory Diseases.1999;47(3):383-388. doi:10.4046/trd.1999.47.3.383

BACKGROUND: Tracheal hamartoma is a very rare cause of upper airway obstruction. Its clinical features can mimic medical conditions, such as bronchial asthma, chronic bronchitis, and so on. CASE: This report presents the case of a 65 year old man whose major symptom was dyspnea. We found a tumor in his distal tracheal lumen, and the tumor was removed with success using rigid bronchoscope. The tumor was histologically proven to be a hamartoma, and his symptoms were much improved. CONCLUSION: It is important to distinguish it from other conditions because medical management is often not helpful. surgical correction-with or without thoracotomy-is inevitable.
Aged ; Airway Obstruction ; Asthma ; Bronchitis, Chronic ; Bronchoscopes ; Dyspnea ; Hamartoma* ; Humans

Aged ; Airway Obstruction ; Asthma ; Bronchitis, Chronic ; Bronchoscopes ; Dyspnea ; Hamartoma* ; Humans

9

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Clinical Analysis of Spontaneous Pneumothorax.

Ji Woong SON ; Jae Yong PARK ; Kwan Young KIM ; Sang Chul CHAE ; Tae Kyong KANG ; Ki Su PARK ; Chang Ho KIM ; Tae Hoon JUNG

Tuberculosis and Respiratory Diseases.1999;47(3):374-382. doi:10.4046/trd.1999.47.3.374

BACKGROUND: The aim of this study was to investigate etiologic factor, treatment, prognosis of spontaneous pneumothorax(SP). MATERIAL AND METHODS: The medical records of 225 cases of SP experienced at Kyungpook University Hospital from Jan. 1996 to Dec. 1997 were retrospectively analyzed. RESULTS: 1. The patients were 128 primary SP and 97 secondary SP. The mean age was 30 +/- 15.5 years in primary SP and 51 +/- 7.4 years in secondary SP. 2. The ratio of male to female was 8 : 1 in primary SP and 5.5 : 1 in secondary SP. Smoker was more common in secondary SP (71.1%) than primary SP(34.4%). About 70% of patients with primary and secondary SP was underweighted. 3. The previous history of SP was present in 28.9% and 25.8% of primary and secondary SP, respectively. 4. The main underlying lung diseases in secondary SP were inactive tuberculosis(68%), active tuberculosis(12.4%) and COPD(11.3%). 5. Tube thoracotomy was performed in 96.8% and 97.9% of primary and secondary SP, respectively. The duration of chest tube insertion was longer in secondary SP (18.2 +/- 19.59 days) than primary SP (7.5 +/- 6.57 days). 6. The open thoracotomy were performed in 22.7% and 10.3% of primary and secondary SP, respectively. The most common indication of open thoracotomy was recurrence on primary SP and persistent air leak in secondary SP. 7. During following-up of 17 +/- 7.8 months, the recurrence rate on patients with conservative treatment was 16.5% and 11.8% of primary and secondary SP, respectively. The recurrence was most common within 1 month after discharge. CONCLUSION: Greater attention and research about SP are necessary for more efficient patient care.
Chest Tubes ; Female ; Gyeongsangbuk-do ; Humans ; Lung Diseases ; Male ; Medical Records ; Patient Care ; Pneumothorax* ; Prognosis ; Recurrence ; Retrospective Studies ; Thinness ; Thoracotomy

Chest Tubes ; Female ; Gyeongsangbuk-do ; Humans ; Lung Diseases ; Male ; Medical Records ; Patient Care ; Pneumothorax* ; Prognosis ; Recurrence ; Retrospective Studies ; Thinness ; Thoracotomy

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Outcomes in Relation to Time of Tracheostomy in Patients with Mechanical Ventilation.

Jeong Eun SHIN ; Tae Rim SHIN ; Young Mi PARK ; Jun Sik NAM ; Seon Hee CHEON ; Jung Hyun CHANG

Tuberculosis and Respiratory Diseases.1999;47(3):365-373. doi:10.4046/trd.1999.47.3.365

BACKGROUND: Despite widespread use of tracheostomy in intensive care unit, it is still controversial to define the best timing from endotracheal intubation to tracheostomy under prolonged mechanical ventilation. Early tracheostomy has an advantage of easy airway maintenance and enhanced patient mobility whereas a disadvantage in view of nosocomial infection and tracheal stenosis. However, there is a controversy about the proper timing of tracheostomy. METHODS: We conducted a retrospective study of the 35 medical and 15 surgical ICU patients who had admitted to Ewha Womans University Mokdong Hospital from January 1996 to August 1998 with the observation of APACHE III score, occurrence of nosocomial infections, and clinical outcomes during 28 days from tracheostomy in terms of early (n=25) vs. late (n=25) tracheostomy. We defined the reference day of early and late tracheostomy as 7th day from intubation. RESULTS: 1. The number of patients were 25 each in early and late tracheostomy group. The mean age were 48 +/- 18 years in early tracheostomy group and 63 +/- 17 years in late tracheostomy group, showing younger in early tracheostomy group. The median duration of intubation prior to tracheostomy was 3 days and 13 days in early and late tracheostomy groups. Organs that caused primary problem were nervous system in 27 cases(54%), pulmonary 14(28%), cardiovascular 4(8%), gastrointestinal 4(8%) and genitourinary 1(2%) in the decreasing order. Prolonged ventilation was the most common reason for purpose of tracheostomy in both groups. 2. APACHE III scores at each time of intubation and tracheostomy were slightly higher in late tracheostomy group but not significant statistically. Day to day APACHE III scores were not different between two groups with observation upto 7th day after tracheostomy. 3. Occurrence of nosocomial infections, weaning from mechanical ventilation, and mortality showed no significant difference between two groups with observation of 28days from tracheostomy. 4. The mortality was increased as the APACHE III score up to 7 days after tracheostomy increased, but there were no increment for the mortality in terms of the time of tracheostomy and the days of ventilator use before tracheostomy. CONCLUSION: The early tracheostomy seems to have no benefit with respect to severity of illness, nosocomial infection, duration of ventilatory support, and mortality. It suggests that the time of tracheostomy is better to be decided on clinical judgement in each case. And in near future, prospective, randomized case-control study is required to confirm these results.
APACHE ; Case-Control Studies ; Cross Infection ; Female ; Humans ; Intensive Care Units ; Intubation ; Intubation, Intratracheal ; Mortality ; Nervous System ; Respiration, Artificial* ; Retrospective Studies ; Tracheal Stenosis ; Tracheostomy* ; Ventilation ; Ventilators, Mechanical ; Weaning

APACHE ; Case-Control Studies ; Cross Infection ; Female ; Humans ; Intensive Care Units ; Intubation ; Intubation, Intratracheal ; Mortality ; Nervous System ; Respiration, Artificial* ; Retrospective Studies ; Tracheal Stenosis ; Tracheostomy* ; Ventilation ; Ventilators, Mechanical ; Weaning

Country

Republic of Korea

Publisher

The Korean Academy of Tuberculosis and Respiratory Diseases

ElectronicLinks

http://www.e-trd.org/

Editor-in-chief

Kisuck Jung

E-mail

katrd@lungkorea.org / katrd@hanmail.net

Abbreviation

Tuberc Respir Dis

Vernacular Journal Title

결핵및호흡기질환

ISSN

1738-3536

EISSN

2005-6184

Year Approved

2007

Current Indexing Status

Currently Indexed

Start Year

Description

Tuberculosis and Respiratory Diseases (Tuberc Respir Dis) is the official journal of the Korean Academy of Tuberculosis and Respiratory Diseases. The journal publishes high-quality, peer-reviewed clinical or research articles that contribute to the understanding of the pathophysiology, diagnosis, and treatment of tuberculosis and other respiratory diseases. The aims of the journal are to publish important articles, encourage the exchange of information between members and related healthcare providers, and improve patient and public health.

Previous Title

Tuberculosis and Respiratory Diseases

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