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Catheter Ablation in Canine Coronary Sinus Using Radiofrequency Energy

Chinese Journal of Interventional Cardiology.1992;0(00):-.

The safety and effectiveness of catheter ablation in coronary sinus using radiofre-quency energy was studied in 16 dogs. Radiofrequency energy(1229?711 J) was applied between electrode catheter placed inside coronary sinus and a chest wall patch. Thirteen dogs were killed approximately half an hour after ablation and three 3 to 4 weeks. Lesion of abltion area were 3. 2?1. 8mm in length, 2. 2?1. 7mm in width and 2. 1?1. 0mm in depth. Microscopic examination showed well circumscribed area of coagultion necrosis (acute period)and fibrosis (chronic period). The coronary atery and mitral apparatus were not involved,nor was the endocadium. No arrhyth-mias except occationally atrial or ventricular premature beats were observed. No hemodynamic changes and rupture of coronary sinus occurred in any dog. Large amount of radiofrequency energy can be safely applied to the coronary sinus. The location of the lesions produced suggests that this technique may be useful for interruption of left-sided atioventricular pathways of patients.

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The Changes of Several Kinds of.Cardiovascular-Regulating Hormones After Percutaneous Balloon Mitral Valvuloplasty

Dazhu LI ; Linsheng CAO

Chinese Journal of Interventional Cardiology.1992;0(00):-.

The plasma levels of atrial natriuretic factor (ANF), angiotension II (AII, vaso-pressin (VP) and endogenous digitalis-like factor (EDLF) were determined in 23 patients with mi-tral stenosis before and after percutaneous balloon mitral valvuloplasty (PBMV). Before PBMV, the plasma levels of ANF and EDLF were elevated in all patients with lower level of All than nor-mal. After the procedure, with a concomitant decrease of left atrial pressure, the plasma ANF de-creased at 15 minutes (from 317. 4?96. 2 to 164. 9?56. 8ng/L , P

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Transcatheter Modification of Atrioventricular Junction With Radiofrequency Energy for Control of Atrioventricular Nodal Reentrant Tachycardia

Runfen CHEN ; Dingjiu HUANG ; Binyao WANG

Chinese Journal of Interventional Cardiology.1992;0(00):-.

Transcatheter atrioventricular (AV) junction ablation with radiofrequency energy was performed in five patients with AV nodal reentrant tachycardia. Disappearance of ventriculoa-trial condcution in all patients was showed and no dual pathway was observed in four patients, in whom three patients occurred first degree AV block after ablation. No tachycardia was showed in all patients in the electrophysiology test and in follow-up of 1. 5-12. 5 months. The results sug-gested that the application of radiofrequency energy may be a suitable and safe therapeutic mothed for modification of AV nodal conduction in patients with AV nodal reentrant tachycardia.

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Transcatheter Electrical Ablation for Treatment of Patients With Refractory Ventricular Tachycardia and Its Long-term Efficacy

Naisheng CAI ; Meixian HE ; Bugao TONG

Chinese Journal of Interventional Cardiology.1992;0(00):-.

Transcatheter electrical ablation was performed in 5 patients, none of them showed clinical effectiveness for treatment of antiarrhythmic drugs, with recurrent sustained ventricular tachycardia (VT). The localization of ventricular ectopic focus mainly depended upon the results of pace mapping. Energy used for each transcatheter electrical ablation (TEA) was usually 150-250J and the total energy was 550J to 800J respectively for each patient. No recurrence of VT was ob-served in 4 cases during 19 to 41 (mean 26. 8) months of follow-up period, two of them without adminstration of drug. Sustained VT relapsed during the 4th months after ablation in one case, however, heart rate during VT was much slower than before. Our experience suggests that long-term effectiveness of TEA for treatment of drug-resist VT is inspiring.

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Accuracy Assess of Five Criterims of Electrocardiogram for Locating Accessory Pathways in Patients With Wolff-Parkinson-White Syndrome

Li LI ; Yuwei ZHANG ; Wuyang QIAN

Chinese Journal of Interventional Cardiology.1992;0(00):-.

The resting 12 lead electrocardiograms (ECG) of 45 patients with Wolff-Parkinson-White syndrome and 30 normal persons were assessed by five criterias for locating the accessory pathway. Golden criteria was established by site of accessory pathway confirmed during epicardial mapping and absent accessory pathway from normal person. Compared five criterias of EGG with golden criteria, the idiosyncrasy of every criteria was 100% and the sensitivity of Rosenbaum's cri-terias, Gallagher's, WHO's, Lindsay's, Reddy's were respectively 93. 3% , 71. 1% , 64. 4% , 60% , 53. 3%. The preliminary feature for locating the accessory pathway of ECG was put forward from advantages of five criterias and observation of this report data.

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Catheter Ablations of Wolff-Parkinson-White Syndrome and Atrioventricular Node Dual Pathways with Radiofrequency Current

Dayi HU ; Lesin WANG ; Kuck KARLHEINZ

Chinese Journal of Interventional Cardiology.1992;0(00):-.

Fourteen patients with Wolff-Parkinson-White syndrome (W-P-W) and 2 pa-tients with atrioventricular node dual pathway (AVNDP) underwent radiofrequency current abla-tion. There were 14 accessory pathways located on the left side of the heart (11 left-free wall. 1 left postseptal, 1 left postlateral and 1 left midseptal), 2 on the right side (1 right anteroseptal, 1 right free-wall). In patients with left side pathways, ablation was attempted via a catheter posi-tioned in the left ventricule directly below the mitral annulus. In patients with right side accessory pathways , the ablation catheter was positioned in the atrial aspect of tricuspid annulus. Accessory pathway conduction was permanently abolished in all the patients (100% ). 2 patients with AVNDP were also successfully ablated by blocking the slow pathways. Plasma CK-MB , SGOT and LDH in-creased moderately in 9 patients (52. 9%) and decreased to normal level after 3～4 days. No severe complications were noted. Conclusion: catheter radiofrequncy current ablation may be an effective and safe therapeutic modality for patients with refractory tachycardias mediated by these path-ways.

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Comparison of Clinical and Economic Effects between Catheter Radoifrequency Current Ablation and Openheart Operation for Chinese Patients with Paroxysmal Supraventricular Tachycardia

Yinglong HOU ; Riying DU ; Zhenjie CAI

Chinese Journal of Interventional Cardiology.1993;0(02):-.

0. 05) in rate of success, recurrence and complication between RFCA and OHO for the patients with AVRT. Medical workers were fewer, operation, du-ration, hospital days (including days of pre-operation preparation and post-operation recovery) and days of looking after the patients in RFCA were shorter than those in OHO,p

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Myocardial Nutrition Study after Myocardial Revascu-Larization by Laser.

Rang DONG ; Daosheng ZHENG

Chinese Journal of Interventional Cardiology.1992;0(00):-.

The myocardial nutrition after myocardial revascu-larization was studied in 14 rabbits with the aid of Nd-YAG laser, before Ligation of the anterior descending branch of the left coronary artery (only ligated LAD in 4 rabbit), the rabbits were seperatively Killed 3 or 5 weekafter operating. Myocardial samples were abtained in the parti of 0 - 2,2 - 4,4 - 6mm from laser hole. Sample numbers were 30 in myocardial revascularization group (MRG); 20 in myocardial Infarction group(MIG); 20 in normal group (NG). Amount of ATP and CP in myocar-dia were determined with luciferase. Resalts.ATP and CP near laser holes were normal 3 week late. This far from laser holes was lower than that of normal myocardia 5 week late. Recover of CP amount was slower than that of ATP amount. Inclusion, myocardial revascularization can play role in myocardial nutrition.

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Modification of atrioventriculat node by radiofrequency ablation of slow pathway with inferior approach in 23 patients with superaventricular tachycardia

Shulin WU ; Haijie LI

Chinese Journal of Interventional Cardiology.1992;0(00):-.

18 patients with atrioventricular nodal reentant tachycardia (AVNRT)and 5 patients with atrioventricular reentrant tachycardia (AVRT) with AVN double pathway (AVNDP) received radiofrequency ablation of slow pathway with inferior approach in order to modify AVN. AVNRT was induced in slow-fast form in 16 patients, in fast-slow form in one patients,and in coexistent slow-fast and fast-slow forms in one patients. Selective ablation of slow pathway was achieved in 18 patients. AVRT was induced in 5 patients (one obvient accessory pathway, 4 concealed accessory pathways) ,4 patients with reentrant cirucit of consisting of anterograde conduction by slow pathway of AVN and retrograde conduction by accessory pathway (AP) , one patient coexistent AVRT and AVNRT. Slow pathway in 5 patients and AP in 3 patients were successfully ablated. Junctional rhythm appeared in 21 patients during duation of discharge of radiofrequency current. No severe complicationwere noted. AVNRT in one patient recurred during a follow-up period of 1 to 15 months. The patient experienced second catheter ablation and was successed. It was suggested radlofrequency ablation of slow pathway with Inferior approach may be a method with high rate of success and less complication.

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Protective effects of ischemic preconditioning with normothermia or hypothermia on schemia/reperfusion in-jury in isolated rat hearts

Shengxi CHEN ; Guilin YIN ; Mingdao YUAN

Chinese Journal of Interventional Cardiology.1996;0(01):-.

Using isolated rat hearts perfused on a langendorff apparatus,ischemic preconditioning (IP) was investigated with 5 min normothermic (at 37℃) or hypothermic (at 30 ℃) ischemia, followed by 10 min of reperfusion before the arrest period, as an adjunct to St. Thomas crystalloid cardioplegia during 180 min ischemia. After basline functional data were obtained, IP was induced 1 control hearts underwent no IP. Results showed that IP improved functional recovery from ischemia during 45 min reperfusion in normothermic ischemic preconditioning group (NP) comparing with normothermic control (NC),P

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