Journal Detail Information

1

Cite

Share

The monitoring of cleft lip with or without cleft palate in China: 1996 - 2000.

Li DAI ; Jun ZHU ; Guang-xuan ZHOU ; Yan-ping WANG ; Lei MIAO

Chinese Journal of Stomatology.2003;38(6):438-440.

OBJECTIVETo describe the epidemiological features of cleft lip with or without cleft palate (CL +/- P) in Chinese perinatals.

METHODSFrom 1996 through 2000, hospital-based cluster sampling method was adopted for collecting data. During that period all live or still births with 28 weeks of gestation or more delivered in monitoring hospitals were assessed within 7 days after birth.

RESULTSThe birth prevalence rates of cleft lip (CL) and of cleft lip with cleft palate (CLP) were 5.03/10,000, 8.97/10,000 respectively, then the rate of CL +/- P was 14.0/10,000. The prevalence rates in urban and rural area, in male and female births were 13.28/10,000 and 15.57/10,000, 16.06/10,000 and 11.40/10,000 respectively. Significant difference was found among maternal-age-specific prevalence rates, and the highest one was observed in >or= 35 maternal age group. 87.25% of CL +/- P was isolated forms. No secular trend was found during that period. The perinatal fatality rate of CL +/- P was 19.04%, and the rate in isolated forms was 12.69%, but the rate in syndromic CL +/- P was as high as 62.60%.

CONCLUSIONSNo decline trend in prevalence rate of CL +/- P was observed during 1996 approximately 2000. Compared with prevalence rates of CL +/- P in some foreign countries, it was higher in China during same period.

Adult ; China ; epidemiology ; Cleft Lip ; epidemiology ; Cleft Palate ; epidemiology ; Female ; Humans ; Incidence ; Male ; Maternal Age ; Pregnancy ; Time Factors

2

Cite

Share

Colony-stimulating factor-1 receptor in rat dental follicle cells.

Hai-jing GU ; Jun-qi LING

Chinese Journal of Stomatology.2003;38(6):435-437.

OBJECTIVETo study localization and expression of CSF-1 receptor protein, in order to discover the CSF-1 and IL-1alpha effects on CSF-1 receptor mRNA levels and to determine if the autocrine effect is inhibited through the CSF-1 receptor.

METHODSImmunolocalization of CSF-1 receptor in the cultured dental follicle cells and in mandibles of the post-natal rats from day 1 to 11 were performed. The effects of different concentrations of CSF-1, IL-1alpha on CSF-1 receptor gene expression were detected by means of RT-PCR.

RESULTSCultured dental follicle cells were immunostained for the CSF-1 receptor. In vivo, immunostaining showed that the CSF-1 receptor was present in the dental follicle of the first mandibular molar at early post-natally and was either absent or greatly reduced by day 11 post-natally. High concentrations of cvCSF-1 reduced the gene expression of the CSF-1 receptor. IL-1alpha had no effects on CSF-1 receptor mRNA levels.

CONCLUSIONSThe expression of CSF-1 receptor reaches a peak early post-natally in the dental follicle of the first mandibular molar of the rat and then subsequently declines. High concentrations of CSF-1 inhibits the expression of CSF-1 receptor, IL-1alpha has no effect on the expression of CSF-1 receptor mRNA.

Animals ; Cells, Cultured ; Dental Sac ; chemistry ; cytology ; Immunohistochemistry ; Interleukin-1 ; pharmacology ; Macrophage Colony-Stimulating Factor ; pharmacology ; RNA, Messenger ; analysis ; Rats ; Rats, Sprague-Dawley ; Receptor, Macrophage Colony-Stimulating Factor ; analysis ; genetics

3

Cite

Share

A study of calcitonin gene-related peptide-immunoreactive nerve fibers of rat molar pulp during traumatic occlusion and after removal.

Zuo-qi HAO ; Hong-chen LIU ; Mei-ling ZHU ; Li-jun DUAN

Chinese Journal of Stomatology.2003;38(6):432-434.

OBJECTIVETo study the effect of traumatic occlusion on CGRP-immunoreactive (CGRP-IR) nerve fibres in rat molar pulp and observe the recovery of CGRP-IR nerve fibres after removal of traumatic occlusion.

METHODSTo observe immunohistochemically the change of CGRP-IR nerve fibres in molar pulp during traumatic occlusion and after removal.

RESULTSThe increase of number, density and morphology of CGRP-IR nerve fibres in traumatic occlusion group was more than in control group, however, the changes of CGRP-IR nerve fibres in removal of traumatic occlusion group were less than in control group.

CONCLUSIONSThe changes of CGRP-IR nerve fibres in number, morphology, and density are induced by traumatic occlusion in rat molar pulp, however, the nerve fibres recover to normal by removal of traumatic occlusion.

Animals ; Calcitonin Gene-Related Peptide ; analysis ; Dental Occlusion, Traumatic ; metabolism ; pathology ; therapy ; Dental Pulp ; innervation ; Immunohistochemistry ; Male ; Molar ; innervation ; Nerve Fibers ; chemistry ; Rats ; Rats, Sprague-Dawley

4

Cite

Share

Expression of homeobox gene Msx-1, Msx-2 and Dlx-2 during murine mandibular first molar development.

Li MA ; Zhi CHEN ; Guang-tai SONG ; Ming-wen FAN ; Qi ZHANG ; Zhi-feng WANG

Chinese Journal of Stomatology.2003;38(6):429-431.

OBJECTIVETo observe the expression of homeobox gene Msx-1, Msx-2 and Dlx-2 during murine mandibular first molar development.

METHODSThe murine heads or mandibles on embryonic days 11-18 (E11-18) and postnatal day 1-3 (P1-3) were removed, fixed and embedded, 5 micro m serial sections were cut in the coronal plane. Msx-1, Msx-2 and Dlx-2 RNA probes were synthesized by in vitro transcription and labeled with digoxigenin. Msx-1, Msx-2 and Dlx-2 mRNA expression was observed after in situ hybridization.

RESULTSDuring molar development Msx-1 transcripts appeared only in mesenchymal cells, not in epithelial cells. Msx-2 and Dlx-2 both expressed in the epithelial and mesenchymal cells. At the initiation stage of the molar development Msx-2 and Dlx-2 had similar expression. At the bud stage (E13-14) Msx-2 mRNA signaling was intensive in the enamel organ and slight in the dental mesenchyme; Dlx-2 signaling was stronger in the dental papilla. At cap stage (E15-16) Msx-2 showed prominent mRNA signaling in enamel knot and Dlx-2 was maximal in the dental papilla. At the late bell stage (P2-3) Msx-2 transcripts were observed in odontoblasts but not labeled in ameloblasts, and Dlx-2 transcripts appeared in ameloblasts but no labeling was seen in odontoblasts.

CONCLUSIONSMsx-1, Msx-2 and Dlx-2 are expressed in various patterns during murine mandibular first molar development, suggesting they possibly play a role in the interaction between the epithelium and mesenchyme during the molar development.

Animals ; DNA-Binding Proteins ; genetics ; Female ; Gene Expression Regulation, Developmental ; Genes, Homeobox ; Homeodomain Proteins ; genetics ; MSX1 Transcription Factor ; Male ; Mandible ; embryology ; Mice ; Molar ; embryology ; RNA, Messenger ; analysis ; Transcription Factors ; genetics

5

Cite

Share

Infection of human papillomavirus in oral benign epithelial proliferation in children.

Lai-kui LIU ; Zhi-xiu HE ; Yi-ning LI ; Xin-zhu YI

Chinese Journal of Stomatology.2003;38(6):426-428.

OBJECTIVETo investigate the presence of HPV infection of oral mucosa proliferative lesions in children and determine the associations of HPV types with oral mucosa lesions in children.

METHODSImmunohistochemical method and in situ hybridization techniques were applied to detect human papillomavirus (HPV) infection in biopsies taken from clinical lesions in oral mucosa of 30 children.

RESULTSThe most frequent lesions detected were SCP (66.7%), followed by CA and FEH. The HPV viral antigen was present in 73.3% (22/30) of the oral benign epithelial proliferative lesions in children. A high frequency HPV was found in CA (6/6) and SCP (15/20) by means of IHC. In the ISH positive case, high risk HPV 16/18 was observed in 77.3% (17/22).

CONCLUSIONThis study demonstrates a high prevalence of HPV infection in children's oral mucosa proliferative lesions, and high-risk HPV16/18 are predominant in children's oral mucosa proliferative lesions.

Adolescent ; Child ; Child, Preschool ; Condylomata Acuminata ; virology ; DNA, Viral ; analysis ; Female ; Focal Epithelial Hyperplasia ; virology ; Humans ; Immunohistochemistry ; Infant ; Male ; Mouth Mucosa ; virology ; Papilloma ; virology ; Papillomaviridae ; isolation & purification

6

Cite

Share

Effect of chewing sugar-free gum after sucrose challenge on dental plaque pH in situ.

Yan-mei DONG ; Yi-chun PAN ; Dong-mei WANG ; Cai-fang CAO

Chinese Journal of Stomatology.2003;38(6):423-425.

OBJECTIVETo evaluate the effect of chewing sugar-free gum after sucrose challenge on dental plaque pH in situ.

METHODS16 healthy volunteers aged 23 - 32 years were screened as subjects. The pH of 48-hour dental plaque was measured using a Beetrode pH microelectrode when subjects chewed Extra sugar-free gum after sucrose challenge.

RESULTSDental plaque pH maintained at resting plaque pH when immediately chewed sugar-free gum after sucrose challenge. Chewing sugar-free gum at 5 min after sucrose challenge, dental plaque pH was raised from 5.59 (measured at 5 min after sucrose challenge) to 6.98 (measured at 10 min after sucrose challenge).

CONCLUSIONSChewing sugar-free gum after sucrose challenge can neutralize organic acid produced by bacteria in dental plaque and rapidly rise plaque pH.

Adult ; Chewing Gum ; Dental Plaque ; metabolism ; prevention & control ; Female ; Humans ; Hydrogen-Ion Concentration ; Male ; Sucrose

7

Cite

Share

Circulating test and analysis of clasp retention.

Qi-min GE ; Fu-qiang ZHANG

Chinese Journal of Stomatology.2003;38(6):420-422.

OBJECTIVETo show the trend of the retention change during the circulation of the clasp dislodging and inserting, and to discuss the proper depth of the undercut for a specific clasp. It is also a basic study for the best designing of RPD.

METHODSThe Chatillon force measuring instrument was used to record the variation of the retention of Co-Cr alloy casting Akers clasp when they were dislodging from undercuts of different depths (0.25 mm, 0.50 mm, 0.75 mm) on bicuspid and molar.

RESULTSThe data was analysed of Correlation and Regression by SPSS 10.0 statistic software. The variations of the retention in the circulation are obvious from the different teeth and different undercut depths. It shows an attenuation trend in circulation (P < 0.01). After 400 times dislodging, in bicuspid group, the retention of the clasp used in 0.50 mm undercut became less than the one used in 0.25 mm undercut. While the retention of the clasp used in 0.75 mm decreases most obviously, it values 0.7670 kg. In molar group, the attenuations of the retention at different depths of undercut are similar, the retentions of the clasp still rank as, from great to less, 0.75 mm, 0.50 mm and 0.25 mm, in the depth of undercut.

CONCLUSIONthe proper depth of the undercut for bicuspid is 0.25 mm, and 0.50 mm for molar.

Dental Clasps ; Dental Prosthesis Retention ; Humans

8

Cite

Share

Effect of IgY solution on dental plaque.

Wen-hui WANG ; Wei-jian WANG ; Bo-xue ZHANG

Chinese Journal of Stomatology.2003;38(6):417-419.

OBJECTIVETo observe the effect of the IgY solution on dental plaque and mutans Streptococci in plaque and in saliva.

METHODSA double-blind study was used. 44 school children at the third grade in test group used the IgY solution for 21 days; 41 children in control group used the placebo. The plaque index, the plaque weight, the level of mutans streptococci in saliva and in plaque were tested for all children.

RESULTSThe plaque weight in test group was (46.4 +/- 31.2) mg at baseline, and (36.6 +/- 25.6) mg at the end of the study (P = 0.007). The IgY solution reduced 21.1% plaque weight. Statistically significant differences for other indices were not shown in this study.

CONCLUSIONThe 0.1% IgY solution reduces the mass of plaque on the tooth surfaces.

Child ; Dental Plaque ; prevention & control ; Double-Blind Method ; Humans ; Immunoglobulins ; administration & dosage ; Solutions

9

Cite

Share

Three dimensional finite element stress analysis on superstructure of the fixed bridge supported by tooth-implant.

Xue-jin WANG ; Yan-min ZHOU ; Hui-ying LIU ; Chang-liang WU

Chinese Journal of Stomatology.2003;38(6):414-416.

OBJECTIVETo reveal the stress distribution in the superstructure of fixed bridge supported by tooth-implant in the process of mastication for improvement of denture design.

METHODSThe stress distribution and displacement of the superstructure were studied and analyzed by means of CT Scan, CAD and three-dimensional finite element when various loads were applied.

RESULTS(1) The stress distribution in abutments under oblique loads at forty-five degrees was uneven and the peak value was 4 - 6 times higher than that under vertical loads. Stress concentration occurred with significant compressive stress. (2) Compressive stress widely distributed in the middle area of occlusal surface of pontic, whose peak value under concentrated loads was significantly higher than that under disperse loads. The loading direction had no effect on the stress concentration. (3) The maximum displacement of implant abutment in medial-distal direction was greater than that of the neck of nature tooth.

CONCLUSIONSThe mechanic complications of superstructure could be prevented by reducing oblique loads and concentrated ones. It is certain that the further improvements of curve-resistance of pontics and press-resistance of abutments are available.

Dental Implants ; Dental Stress Analysis ; Denture, Partial, Fixed ; Finite Element Analysis ; Humans

10

Cite

Share

Speech outcomes in patients of maxillary reconstruction with free fibula composite flap.

Xin PENG ; Lian MA ; Chi MAO ; Guang-yan YU ; Chuan-bin GUO ; Xiao-jing LI

Chinese Journal of Stomatology.2003;38(6):411-413.

OBJECTIVETo evaluate speech outcomes in patients of maxillary reconstruction with free fibula composite flap.

METHODSSpeech measurements of 20 patients of maxillary reconstruction with free fibula composite flap were collected. Palatopharyngeal valve, the symmetry and movement of soft palate, hypernasality and nasal emission were examined by nasoendoscopy. At the same time the speech intelligibility was measured.

RESULTSNo palatopharyngeal valve insufficiency was found and all the soft palates had good symmetry and movement. The average speech intelligibility was 98.4%.

CONCLUSIONSFree fibula composite flap can reconstruct the phonatory structure and support the function of soft palate, which can restorate speech function well. It is a good choice for maxillary reconstruction.

Adult ; Female ; Fibula ; Humans ; Male ; Maxilla ; surgery ; Middle Aged ; Speech Intelligibility ; Surgical Flaps

DISPLAY OPTIONS

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share