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Small cell carcinoma of the ovary is a rare, distinctive, highly malignant, and undifferenciated carcinoma of unknown cullular lineage. It tends to occur in young women, and there is an associated paraneoplastic hypercalcemia in as many as two-thirds of reported cases. It has very poor prognosis and has been exceedingly difficult to treat. Thus a proven regimen of adjuvant therapy is not defined yet. We report here the two cases of primary small cell carcinoma of the ovary, which is presented with a brief review of the literature.
Carcinoma, Small Cell* ; Female ; Humans ; Hypercalcemia ; Ovary* ; Prognosis

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Two Cases of Primary Carcinoma of the Peritoneum.

Joong Sik SHIN ; Sam Hyun CHO ; Jung Bae YOO ; Seung Ryong KIM ; Soo Hyun CHO ; Kyung Tai KIM ; Youn Yeung HWANG ; Seok Hoon JEON ; Jung Dal LEE

Korean Journal of Gynecologic Oncology and Colposcopy.1996;7(3):248-253.

The primary malignant tumor of the peritoneum also known as primary peritoneal carcinoma or primary peritoneal papillary serous carcinoma is rare and involves the peritoneum, especially the pelvic peritoneum of female patients. It is difficult to differentiate histologically between papillary mesothelioma, primary ovarian tumor and primary peritoneal carcinoma. We report two cases of the primary peritoneal carcinoma with clinical presentation and histologic characteristics.
Diagnosis, Differential ; Female ; Humans ; Mesothelioma ; Peritoneum*

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A Case of Ovarian Mucinous Cystadenocarcinoma with Mural Nodule of Anaplastic Carcinoma.

Mee Sook ROH ; Sook Hee HONG ; Tai Young HWANG ; Hyun Ho KIM ; Goo Hwa JE

Korean Journal of Gynecologic Oncology and Colposcopy.1996;7(3):243-247.

Mural nodules in ovarian mucinous tumors, whether benign, borderline, or malignant, have been described by several authors since Prat and Scully first described sarcoma or sarcoma-like mural nodules occurring in association with mucinous epithelial neoplasia in 1979. Three distinct types of the mural nodule have been identified; i. e., 1) sarcoma-like lesion, 2) true mesenchymal sarcome, and 3) anaplastic carcinoma simulating a sarcoma. Mural nodules of sarcomatous and carcinomatous foci associated with mucinous ovarian tumors should be separated from sarcoma-like nodules because of the poor prognosis of the former compared to the favorable prognosis of the latter. We experienced a case of ovarian mucinous cystadenocarcinoma with sarcoma-appearing mural nodule of anaplastic carcinoma occurred in a 59-year-old woman and reported with brief review of the literatures.
Carcinoma* ; Cystadenocarcinoma, Mucinous* ; Female ; Humans ; Middle Aged ; Mucins* ; Ovary ; Prognosis ; Sarcoma

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A Case of Primary Carcinoma of the Fallopian Tube.

Chan Ho SONG ; Choon Soo RHOO ; Oh Seong LEE ; Yun Lee RHEE ; Heung Tae NOH

Korean Journal of Gynecologic Oncology and Colposcopy.1996;7(3):236-242.

Primary carcinoma of the uterine tube is one of the least common gynecologic malignancies with a reported incidence of approximately 0.3%. As a result of it, the experience of any one physian is limited. Almost all cases are adenocarcinoma and the cilinical presentation is generally nonspecific, of which the most common symptom is postmenopausal vaginal bleeding. Primary fallopian tube carcinima is infrequently diagnosed before explolatory laparotomy and the majority of patients have extensive disease at diagnosis. We have experienced a case of fallopian tube cancer and report with brief review of literature
Adenocarcinoma ; Diagnosis ; Fallopian Tube Neoplasms ; Fallopian Tubes* ; Female ; Humans ; Incidence ; Laparotomy ; Uterine Hemorrhage

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DNA Patterns by Flow Cytometric Analysis of Squamous Carcinoma Cells of the Cervix Uteri : Relations with Prognosis and Biochemical Characteristics.

Duck Jin NHA ; Soo Pyung KIM

Korean Journal of Gynecologic Oncology and Colposcopy.1990;1(1):80-89.

This study was performed to find out the relationship between DNA pattern by flow cytometry and the prognosis of cervical squamous cell carcinoma, The subjects were 71 patients who were admitted to Catholic University Medical College Kangnam St. Marys Hospital from September 1983 to May 1989 under the diagnosis of cervical squamous cell carainoma. Samples were obtained from the subjects before chemotherapy or radiation therapy, and a through follow up stduy was carried out an the subjects. The authors obserued the relations between flow cytometric DNA pattern and clinical stage, age of patients, histopathological findings and tumor markers, with the following results. 1. The S-phase of the cell cycle increased significantly in Stages I, ll and III-IV compared to that of Stage O.However, there was no difference between Stages in G0/G1 phase and G2/M phase. 2. The incidence of aneuploid tumor increased significantly according to stage with the rates of increase reaching 22, 22%, 31.57%, 44.44% and 68.75% respectively in Stages 0, I, II, and Ill-lV. 3. The incidence of aneuploid tumor increased significantly depending on the age of patients with the rates standing at 21.42%, 31.58%, 40.90% and 68.75% respectively in the groups of below 40, 41-50, 51-60, and 61 years and over. 4. As for the relation between histopathological findings and the incidenee of aneuploid tumor, no difference was found according to the degree of differentiation, but there were significant differences between the keratinization group(23.07%) and the non keratinization group(51.11%).
Aneuploidy ; Carcinoma, Squamous Cell* ; Cell Cycle ; Cervix Uteri* ; Diagnosis ; DNA* ; Drug Therapy ; Female ; Flow Cytometry ; Follow-Up Studies ; Humans ; Incidence ; Prognosis* ; Biomarkers, Tumor

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