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Clinical analysis of testicular trauma: a report of 30 cases

Zhenchuan CHEN ; Xuezhu YU ; Fangsheng DAI ; Shu WANG

Chinese Journal of Trauma.1990;0(03):-.

Objective To explore the characteristics of diagnosis a nd treatment of testicular trauma. Methods A retrospective study was done on 30 cases of testicular trauma. The treatment effects of non -operation and operation on different types of injuries were observed and com pared. Results Follow-up time ranged from two months to tw o years. There were three cases with testicular atrophy, one with chronic pain l asting for one year and eight with non-operation. All of 22 cases treated with surgical operation were good except for one with sperm disorder due to bilateral testicular trauma. Conclusions Testicular trauma is a speci al type of trauma. Ultrasound is an important diagnostic method for testicular trauma. Surgical exploration should be performed as soon as possible so as to a void testicular atrophy and sperm disorder.

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Treatment of severe lower extremity trauma

Qifeng GUO ; Zhonghe XU

Chinese Journal of Trauma.1990;0(03):-.

Objective To explore the treatment approach to severe l ower extremity trauma. Methods A retrospective study was ca rried out in 42 cases with severe lower extremity trauma from 1989 to 1999. Mang led extremity severity score (MESS) was 6.24?1.45 in all the cases, among which were 34 cases with MESS

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Dose-effect effects of relating bone growth factors on proliferation and diffe rentiation of periosteal cells in vitro

Chao ZHANG ; Yunyu HU ; Jianqiang XU ; Jianping BAI

Chinese Journal of Trauma.1990;0(03):-.

Objective To investigate the dose-effect effects of th ree relating bone growth factors, dexamethasone, recombinant human basic fibro blastic growth factor (rhFGF) and recombinant human bone morphogenetic protein- 2 (rhBMP-2), on proliferation and differentiation of periosteal cells so as to provide experimental basis for their further application in bone tissue engineer ing. Methods Periosteal cells were isolated and cultured in vitro and then exposed to dexamethasone (10 -8 mol/L, 10 -7 mol/L and 10 -6 mol/L), rhFGF (50 ng/ml, 200 ng/ml and 500 ng/ml) and rhBMP-2 (50 n g/ml, 500 ng/ml and 1 000 ng/ml) respectively. At the 4th and 7th days respectiv ely, the culture stopped and the total protein and alkaline phosphatase (ALP) ac tivities were measured. ResultsDexamethasone at concentratio n of 10 -6 mol/L significantly inhibited protein synthesis without obvious effects on ALP expression. The rhFGF at various concentrations significantly pro moted cell proliferation but inhibited ALP activity. The rhBMP-2 at various con centrations exerted insignificant effect on cell proliferation. In comparison, A LP expression was significantly enhanced by treatment of rhBMP-2 at concentrati on of 500 ng/ml and 1 000 ng/ml ( P

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Analysis on cats' death factors after craniocerebral missile wound under different temperature and humidity

Dexuan MA ; Yanwu GUO ; Ruxiang XU

Chinese Journal of Trauma.1990;0(03):-.

ObjectiveTo investigate the changing behavior of cats' vital signs and death factors after craniocerebral missile wound in the environme nt of high temperature and humidity. MethodsA total of 32 hy brid cats were randomly divided into four groups and respectively put into the f ollowing environments after wound, ie, Group A at 25℃ with relative humidity (R H) of 50%, Group B at 35℃ with RH 85%, Group C at 38℃ with RH 90% and Group D at 40℃ with RH 95%. Then, blood pressure, pulse, respiratory frequency and body temperature were recorded every 10 minutes for six hours. Results The vital signs of normal gunshot wound group during the experiment were stable, while body temperature, respiratory frequency and heart rate of cats in each group were significantly different at the same time point with the increa se of temperature and humidity ( P

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Analysis on 1894 cases of road traffic injuries in the Qinghai-Tibet Plateau

Qian WANG ; Xianghai YU ; Xianglin HU ; Xuke MAO ; Yunbing WANG ; Yuwei CHEN

Chinese Journal of Trauma.1990;0(03):-.

ObjectiveTo discuss the epidemiological characteristic s of road traffic injuries in the Qinghai-Tibet Plateau and explore effective pre ventive measures against traffic accidents in the plateau as well as correspondi ng emergency treatment methods.MethodsA retrospective statis tical analysis was carried out in 1 894 cases of traffic injuries with detailed data admitted in our hospital from January 1980 to December 2000. Resu ltsMost of the traffic accidents occurred on the Qinghai-Tibet road, accounting for 68.0% (1 288/1 894). Of the patients with serious traffic inju ries, 54.0% (1 022/1 894) were in need of hospitalization. The patients who first entered into the plateau accounted for 61.1% (1 158/ 1 894). Death occurre d in 108 cases accounting for 5.7%. The duration from injury to treatment was ve ry long, average over six hours. Furthermore, the patients received no any manag ement before treatment in the hospital. ConclusionsHypoxia i n the plateau, unclear road sign and fatigue driving are the main factors leadin g to traffic accidents. Lack of health care units, serious hypoxia, long deliver y time and carriers' deficiency in medical knowledge are the main causes for gr eat amount of casualties.

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Effect of mild hypothermia on the opening of tight junction of cerebral endothelial cells following traumatic brain injury

Runlong LAI ; Dexiang ZHOU ; Fengren ZHENG

Chinese Journal of Trauma.1993;0(05):-.

Objective To observe the effect of early mild hypothermia on the opening of tight junction of cerebral endothelial cells following traumatic brain injury in order to illustrate possible mechanism of low permeability of blood brain barrier (BBB) treated by mild hypothermia. Methods A total of 90 Wistar rats were randomly divided into normothermia control group (n=10),normothermia injury group (n=40) and mild hypothermia group (n=40). The opening state and its extent of tight junction were observed using lanthanum trace labeling with electron microscope. At the same time,water content of cerebral tissue at different phases in normothermia injury group and mild hypothermia group was measured by means of dry-wet weight and analyzed statistically. Results The tight junction was under preliminary opening three hours after trauma and reached the maximum opening within 24-48 hours after trauma,lasting for 72 hours in the normothermia injury group. However,slight opening appeared only in the mild hypothermia group. Water content of cerebral tissue in the mild hypothermia group lessened obviously in contrast to that in the normothermia injury group,with significant difference 3,24 and 72 hours after trauma ( P

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I-stage combination operation of anterior and posterior approaches for anterior and posterior compression of cervical spinal cord

Xueli QIU ; Bendan LIN ; Zhigang ZHONG ; Yishan HU ; Yufeng ZHANG

Chinese Journal of Trauma.1993;0(05):-.

Objective To explore the surgical treatments through anterior and posterior approaches for anterior and posterior compression of cervical spinal cord. Methods The clinical data of 25 cases of anterior and posterior compression of cervical spinal cord from June 1999 to November 2003 were summarized retrospectively. There were 18 males and seven females with age range of 28-56 years (average 36.4 years). Of all,18 cases were with tricolumnae fractures of cervical spine caused by traffic injury,five with cervical herniation and two with malignant macrophage tumor in vertebral body and annex and vertebral lamina. Results All 25 cases underwent internal fixation decompression with I-stage combination operation of anterior and posterior approaches. Of 18 cases with tricolumnae fractures,one died and 17 recovered in various degrees. In five cases with cervical herniation,the positive sign disappeared basically. Two cases of malignant giant-cell tumor appeared metastatic carcinoma in the lungs 10 months after operation. Conclusions The I-stage combination operation of anterior and posterior approaches is an ideal way for the patients suffering from anteropsterospinal compression in cervical spinal cord. It can not only decompress completely the cervical spinal cord,stabilize the wounded cervical vertebra,but also facilitate nursing and function training and be beneficial to the recovery of spinal cord function.

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Clinical observation of a modified anterior fixation technique for thoracolumbar fractures

Qing WANG ; Yueming SONG

Chinese Journal of Trauma.1993;0(05):-.

Objective To modify the anterior fixation technique for thoracolumbar fractures so as to reduce blood loss and improve the success rate of the first vertebral screw implantation. Methods Only surface artery of the injured vertebrae was ligated and the discs adjacent to the burst vertebra excised. Then,the mass autograft ilium was harvested with most cartilage terminal lamina left. The bursted vertebra was resected so that the vertebral canal could be decompressed thoroughly. Structural ilium graft was performed,followed by Z-plate being placed and locked. Results The modified operative technique was used to treat 87 cases,of which 76 cases of fresh thoracolumbar fracture had hemorrhage capacity about 400-800 ml (average 560 ml) as well as operation time for 2.5-3 hours,and 11 cases with old fractures had hemorrhage capacity about 800-1 200 ml (average 1 080 ml) as well as operative time for 3.5-4 hours. Eighty-one cases with kyphosis deformity was completely corrected,four cases had kyphosis deformity of 5?-8? and two lordosis. A total of 39 cases with post-operative paralysis basically recovered,28 partially recovered,nine recovered fractionally and 11 was beyond recovery. No aggravation was found in post-operative nerve syndrome. Conclusions The modified anterior fixation technique is excellent in reducing blood loss,shortening the operation time and increasing the success rate of the primary vertebral screw implantation. [

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Early treatment and Ⅰ-stage repair of acute facial and brain injuries

Jianwen LI ; Changcai CHEN ; Zhibin LI ; Linqiong TAN

Chinese Journal of Trauma.1993;0(05):-.

Objective To study the method for early treatment and Ⅰ-stage repair of the acute facial and brain injuries and its significance. Methods A retrospective study was performed in 38 cases with acute cranial injury,who underwent early treatment and surgical repair of the cranial bone and/or dura defects with self-tissues,glue material and titanium net depending on individual conditions. Of all,33 cases (87%) received Ⅰ-stage repair. Antibiotic therapy was performed in all the cases after operation. Results All patients recovered with satisfactory regional appearance. No intracranial infection or rhinorrhea of cerebral spinal fluid occurred among them during the follow-up for from six months to 11 years. Conclusion For the acute facial and brain injuries,early treatment and Ⅰ-stage repair based on the injury site and injury severity can attain safe and effective results.

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Low-dosage radiosurgical treatment for intractable epilepsy following brain injury through positron emission tomography localization

Kewan WANG ; Songtao QI ; Huaping WU ; Kaijun YANG

Chinese Journal of Trauma.1993;0(05):-.

Objective To treat the patients suffering from intractable epilepsy after brain injury with low-dosage linac accelerator stereotactic radiosurgery through positron emission tomography (PET) localization. Methods PET examination based on 18 F-2-fluorine-2-deglucose (FDG) was carried out in 32 patients in order to localize epileptogenic foci followed by radiosurgery with peripheral radiation dose of 9-13 Gy. The follow-up was conducted over one year. The seizure frequency of epilepsy was recorded to evaluate the therapeutic effect. Results The PET imaging showed that the cortical area around the cerebromalacia caused by primary injury presented low metabolic change. The metabolic changes in different injury areas mainly concentrated in the epileptic foci. In some cases,the low metabolic areas not only was localized at the part of impact lesion but also at the part of contrecoup lesion. The seizure frequency gradually decreased after radiosurgical treatment in most patients,with obvious statistical significance compared with pretreatment. According to Wieser's classification of operative effect,the cases at the grades Ⅰ-Ⅱ accounted for 44% (14/32),grades Ⅲ-Ⅳ for 41% (13/32) and grades Ⅴ-Ⅵ for 16%(5/32). No fresh complications were found in all the cases. Conclusions Low-dosage stereotactic radiosurgery with the PET localization is a safe,effective and minimally invasive surgical approach to intractable posttraumatic epilepsy.

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