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Methylprednislone in treatment of severe idiopathic thrombocytopenic purpura.

Yanling WANG ; Zhanfeng LIU ; Zhigang DU

Clinical Medicine of China.2001;0(08):-.

50?10~9/L in MP group was 1,10,19,19 and in control group was 0,0,2,2,respectively.The ratio of the total effi- ciency was 93.7% in the treatment group and 80.6% in control group,respectively.The clinical efficacy was dif- ferent significant between groups after 2 weeks(P0.05).Conclusion High dose MP is more effective in the patients and with obvious hemorrhagic tendency than that those of the tradition- al treatment;whereas the traditional treatment is available for other severe ITP patients.

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Clinical observation of misoprostol on prevention of postpartum hemorrhage

Xiaoqin LIANG

Clinical Medicine of China.2001;17(4):315-.

Objective To observe the effects of misoprostol on prevention of postpartum hemorrhage.Methods 200 cases of full-term pregnancy intravaginal labor were randomly divided into misoprostol groups (n=100) and control groups (n=100).The misoprostol groups were treated with misoprostol 400 μg PO after labor and control groups were treated with oxytocin 20 U IV after labor.Results The average time interval of the third stage was (6.10±3.35) min in misoprostol groups,whereas (10.00±3.45) min in controls.There was significant difference between two groups (P＜0.01).The average quantity of blood loss in 2 h after labor was (150.30±34.00) ml in misoprostol groups,whereas (240.60±57.30) ml in controls.Conclusion Better effects of misoprostol than oxytocin were proved on preventing postpartum hemorrhage.

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The clinical effect of aescuven forte on the elderly with scrotal edema

Haipeng ZHU

Clinical Medicine of China.2014;(7):759-761,762. doi:10.3760/cma.j.issn.1008-6315.2014.07.032

Objective To evaluate the efficacy and safety of Aescuven forte on treating elderly patients with scrotal edema. Methods Eighty-two patients with scrotal edema were randomly divided into control group and treatment group(41cases for each group). Patients in the control group received physical therapy as well as oral Furosemide tablets for 20 mg and 2 times/ d,while in treatment group were given 450 mg oral Aescuven forte (2 times/ d),and 300 mg Aescuven forte at 10 d besides the treatment as the control group. The total treatment period was 20 days. The information of scrotal volume,score of discomfort or pain,scrotal ulcer healing time were collected. Results After 20 d treatment,the scrotal diameter in treatment group was(7. 81 ± 0. 64)cm,shorter than that before treatment(13. 30 ± 0. 73)cm,and the difference was statistically significant( t = 2. 201,P< 0. 05). Scrotal diameter of the control group before and after treatment were(13. 25 ± 0. 71),(10. 71 ± 0. 65) cm,and there were statistically significant differences( t = 2. 369,P < 0. 05). After treatment,the decreases degree of scrotal diameter in the treatment group was higher than control group( t = 2. 304,P < 0. 05). After treatment,scrotal ulcer healing rate,healing time in treatment groups were 100%(11 / 11)and(14. 1 ± 1. 8)d, and 70%(7 / 10)and(17. 1 ± 1. 9)d in control group,and there were significant difference( χ2 = 4. 880,P= 0. 030;t = 2. 713,P = 0. 016). There was no significant difference in terms of the clinical symptom score between two group before treatment( P > 0. 05). After treatment,the level of pain and discomfort,voiding symptoms,life quality score were(7. 35 ± 3. 08),(3. 43 ± 1. 91),(5. 89 ± 2. 11),lower than those in the control group((8. 47 ± 3. 07),(4. 52 ± 2. 19),(6. 96 ± 2. 13)),and the differences were statistically significant (t = 2. 260,2. 382,2. 319,P < 0. 05). The total effective rate of treatment group was 87. 8%(36 / 41),higher than that in control group(65. 8%(27 / 41)),and there was significant difference(χ2 = 4. 580,P < 0. 01). In the periods of treatment,no adverse reaction between two groups was occurred. Conclusion The use of Aescuven forte combine with diuretic has a synergistic effect and significantly improve the clinical symptoms of elderly patients with scrotal edema in terms of eliminating edema,promoting healing,relieving scrotal ulcer wound pain, improving voiding symptoms and the quality of life. And there is no side effect.

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A cliucal observation of treatment with bifdobiogen in early neonatal hyperbilirubinemia

Fangqing XUE ; Yuan YANG

Clinical Medicine of China.1999;0(02):-.

Objective To compare the effects of bifidobiogen with enzyme inductor(luminal, nikethamidum) in treatment early neonatal hyperbilirubinemia. Methods 92 babies with early neonatal hyperbilirubinemia were divided into 2 groups, randomly. 49 patients were treated with bifidobiogen 350 mg/(kg. d) and phototherapy. Other 43 patients were treated with enzyme lnductor luminal 5mg/(kg. d) ; nikethamidum 100mg/(kg. d)and phototherapy as the control group. Results The total effective rate in the treatment gr0up(77. 6% ) was higher than that in the control group (44. 2% ), P

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Percutanenous intrapulmonary injection of IL-2 plus radiotherapy for luug cancer

Hong GE ; Yue JIANG ; Mei SANG

Clinical Medicine of China.1999;0(02):-.

Objective To evaluate the effects of percutanenous intrapulmonary injecti0n 0f IL-2 plus radiotherapy for lung cancer. Methods Twenty-two patients with inoperable non small cell lung cancer received percutanenous intrapulmonary injection of 100U ? 6 in 6 weeks; and radiation dose was 60 Gy/6wks. Results The total effective response rate (CR+PR) was 95. 4 % with the complete response rate (CR) of 40. 9 %. Couclusion Percutanenous intrapulmomary injection of IL-2 plus radiotherapy could improve the control rate of the patients with lung cancer.

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Angina pectoris after thoracotomy

Siyuan WANG ; Liancheng YU ; Jian GUAN

Clinical Medicine of China.1999;0(02):-.

Objective To summarize the clinical features of angina pectoris after thoracotomy. Methods Eight males with a mean age of 60? 5. 4 years were reported and analyzed, of which four patients underwent esphagectomy, three patients esophagogastrectomy and 1 patient pneumonectomy. Results Three cases were attacked angina pectoris after surgery 2~4 h, three cases in 5~12 h, one case in 36 h, and one case in 72h. Acute mocardial infarction of different degrees happened in five cases, and one case died. Conclusion Angina pectorls after thoracotomy is very dangerous to the patlents and not easily distinguished from chest pain after thoracotomy. It's important for the surgeons to analysis comprensively , diagnose as early as posslble and treat immediately.

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Clinical analysis of 27 cases of thoraco-abdominal injury with diaphragmatic rupture

Rongzun LONG ; Deyuan LUO ; Miaolong HUANG

Clinical Medicine of China.2000;0(09):-.

Objective To study the clinical features and treatment experience in the treatment of thoraco abdominal injury with diaphragmatic rupture.Methods Clinical data of 27 patients suffering from thoraco-abdominal injury with diaphragmatic rupture were analysed retrospectively.Results Injuries of this kind are usually complicated involving mostly the organ injuries,which are not obvious in clinical indications. In the present study group,27 cases were treated surgically,of whom 24 healed and 3 died(11.1%).Conclusion Early diagnosis and timely operation are the key steps in reducing the complications and mortality.

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Clinical study of low-molecular weight heparin on the prevention of acute closure after percutaneous intracavitary coronary angioplasty

Xiangru LIU ; Guojin HUANG ; Xiaojun TAN

Clinical Medicine of China.2000;0(11):-.

Objective To evaluate the safety and efficacy of low-molecular weight heparin on the prevention of acute closure after percutaneous intracavitary coronary angioplasty.Methods 73 patients were randomly assigned to LMWH and SH groups.All patients underwent SPECT or CAG.Myocardial ischemia and hemorrhage complication were analyzed.Results In Group LMWH,no case of hemorrhage complication occurred,and in 3 cases angina occurred within 24h after the operation,which was proved by CAG to be acute closure of target vessel (the incidence rate 8.6%) .In Group SH,gum and subcutaneous hemorrhage occurred to 2 cases within 7h after the operation,hematuria occurred to 2 cases within 12h and one case died from cerebral hemorrhage,which was confirmed by CT (the total hemorrhage incidence 13.2%).Another 4 cases in Group SH suffered from re-occurrence of angina,which was confirmed by CAG to be acute closure of target vessel (10.5%).There was significant difference in hemorrhage complication between the two groups (P0.05)。Conclusion The results suggest that LMWH is safe and effective in the prevention of acute closure after native vessel coronary angioplasty.

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Clinical analysis of the pathological fracture in femur

Zaichun DENG ; Zenggan CHEN ; Dunhua ZHANG

Clinical Medicine of China.2000;0(11):-.

Objective To study the etiolgy and clinical features of pathological fracture in femur. Methods 17 cases of pathological fracture in femur,including 10 males and 7 females with average age 39.5(13～74),were all treated surgically and their pathological diagnosis were achieved,which were consistent with the clinical diagnosis.Results 12 patients (70.59%) suffered from fracture resulted from malignant tumor,of which lung cancer and breast cancer were the commonest with 3 cases respectively (50%).The fracture of proximal end accounted for 65%.8 cases of spontaneous fracture and 2 cases of multiple fracture were all malignancy sufferers.Conclusion Malignancy is the main cause of pathological fracture in femur,of which lung cancer and breast cancer are the commonest.Proximal end of femur is the most frequent part to which fracture happens.Both spontaneous and multiple fractures are resulted from malignancy.

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Analysis and classification of functional dyspepsia

Hong TIAN ; Hanjian ZHOU ; Lan GE

Clinical Medicine of China.2000;0(11):-.

Objective To investigate the proportions of the functional dyspepsia (FD) subgroups and to explore theri relationship with Helicobacter pylori (HP).Methods 186 cases with FD received questionaires about their condition and were typed according to their symptom.HP was detected through urease test,spear technique and cultivation.Results The proportion and HP-positive rate of the subgroup were 11.29%,14.24% in reflux-type dyspepsia,13.98%,46.15% in ulcer-type dyspepsin,48.39%,41.11% in dysmotility-type dyspepsia and 26.34%, 38.78% in complex dyspepsia,respectively.The total HP-positive rate of FD is 38.17%.Conclusion Dysmotility-type dyspepsia is most common.Some subgroups are overlapping with each other.There is no relationship between FD and HP.The HP-positive rate of the reflux-type dyspepsia is lower.This observation suggests that HP may have protective effects on esophagus.

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