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Singapore medical journal

1960  to  Present  ISSN: 0037-5675

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Successful pregnancy with laparoscopic oocyte retrieval and in-vitro fertilisation in mullerian agenesis.

G A Rama RAJU ; G B HARANATH ; K M KRISHNA ; G J PRAKASH ; K MADAN

Singapore medical journal.2006;47(4):329-331.

A 28-year-old woman with mullerian agenesis presented with primary infertility and was considered for laparoscopic oocyte retrieval and in-vitro fertilisation. Her 27-year-old younger sister served as a gestational carrier. The patient underwent ovarian stimulation and 11 mature oocytes were retrieved by laparoscopy. After successful in-vitro fertilisation, two embryos were transferred to the gestational carrier. Two weeks after embryo transfer, the pregnancy was confirmed by serum human chorionic gonadotropin levels. Another two weeks later, an ongoing singleton pregnancy with foetal heartbeat was confirmed by transvaginal ultrasonography.
Adult ; Female ; Fertilization in Vitro ; methods ; Humans ; Infertility, Female ; genetics ; Mullerian Ducts ; abnormalities ; Oocytes ; Pregnancy ; Surrogate Mothers ; Syndrome ; Tissue and Organ Harvesting ; Urogenital Abnormalities

Adult ; Female ; Fertilization in Vitro ; methods ; Humans ; Infertility, Female ; genetics ; Mullerian Ducts ; abnormalities ; Oocytes ; Pregnancy ; Surrogate Mothers ; Syndrome ; Tissue and Organ Harvesting ; Urogenital Abnormalities

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Characteristics and outcomes of paracetamol poisoning cases at a general hospital in Northern Malaysia.

Z Mohd ZAIN ; A I FATHELRAHMAN ; A F Ab RAHMAN

Singapore medical journal.2006;47(2):134-137.

INTRODUCTIONParacetamol is available as an over-the-counter medication in many countries including Malaysia. This drug has been implicated in many poisoning cases admitted to hospitals throughout the country.

METHODSWe conducted a three-year retrospective review of 165 medical records of patients admitted to the Penang General Hospital for acute paracetamol poisoning. Cases were identified according to the discharge diagnosis documented in their medical records.

RESULTSAcute paracetamol poisoning occurred in all major ethnic groups. About 70 percent of our patients were female. There was minimal involvement of children. Admissions were more likely to be due to deliberate ingestions rather than accidental poisoning. In most cases, serum concentrations data plotted on the Rumack-Matthew nomogram predicted the majority of cases to be unlikely to be hepatotoxic, which were consistent with their mild clinical courses. Patients who acutely ingested more than 140 mg/kg or predicted to be hepatotoxic, based on their serum concentrations, had a significantly longer hospital stay.

CONCLUSIONAlthough acute paracetamol poisoning was common, the outcome was generally good.


Acetaminophen ; poisoning ; Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Dose-Response Relationship, Drug ; Drug Overdose ; epidemiology ; therapy ; Female ; Humans ; Infant ; Infant, Newborn ; Malaysia ; epidemiology ; Male ; Middle Aged ; Nomograms ; Retrospective Studies ; Treatment Outcome

Acetaminophen ; poisoning ; Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Dose-Response Relationship, Drug ; Drug Overdose ; epidemiology ; therapy ; Female ; Humans ; Infant ; Infant, Newborn ; Malaysia ; epidemiology ; Male ; Middle Aged ; Nomograms ; Retrospective Studies ; Treatment Outcome

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The liver in surgery.

J Prema RAJ

Singapore medical journal.2006;47(2):106-108.


Decision Making ; Humans ; Liver Diseases ; Perioperative Care ; Postoperative Complications ; prevention & control ; Surgical Procedures, Operative

Decision Making ; Humans ; Liver Diseases ; Perioperative Care ; Postoperative Complications ; prevention & control ; Surgical Procedures, Operative

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Charles Darwin: history's most famous naturalist.

James P EVANS

Singapore medical journal.2005;46(12):738-738.


Biological Evolution ; History, 19th Century

Biological Evolution ; History, 19th Century

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Charles Darwin: history's most famous naturalist.

Singapore medical journal.2005;46(12):738-author reply 739.


Bible ; Biological Evolution ; Geology ; History, 19th Century ; Religion and Science

Bible ; Biological Evolution ; Geology ; History, 19th Century ; Religion and Science

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Darwin: fairly good for a medical school dropout.

John H LANGE

Singapore medical journal.2005;46(12):737-737.


Biological Evolution ; History, 19th Century ; Medicine ; trends

Biological Evolution ; History, 19th Century ; Medicine ; trends

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Are the World Health Organisation case definitions for severe acute respiratory syndrome sufficient at initial assessment?

Paul A TAMBYAH ; Louis Y A CHAI ; Dale A FISHER

Singapore medical journal.2005;46(12):736-736.


Diagnostic Errors ; prevention & control ; Emergency Service, Hospital ; Humans ; Severe Acute Respiratory Syndrome ; diagnosis ; World Health Organization

Diagnostic Errors ; prevention & control ; Emergency Service, Hospital ; Humans ; Severe Acute Respiratory Syndrome ; diagnosis ; World Health Organization

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Hypertension in patients with type 2 diabetes mellitus: management needs to be more intensified.

Ali Khan KHUWAJA ; Riaz QURESHI

Singapore medical journal.2005;46(12):735-735.


Diabetes Mellitus, Type 2 ; complications ; Guideline Adherence ; Humans ; Hypertension ; complications ; drug therapy ; Practice Guidelines as Topic

Diabetes Mellitus, Type 2 ; complications ; Guideline Adherence ; Humans ; Hypertension ; complications ; drug therapy ; Practice Guidelines as Topic

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Brown fat uptake of 18F-FDG on dual time point PET/CT imaging.

A R Hairil RASHMIZAL ; A R NORAINI ; C ROSSETTI ; N Abdul JALIL

Singapore medical journal.2010;51(2):e37-9.

The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax), with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two images ranged from -20 percent to +20 percent. Based on our observations, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat.
Adipose Tissue, Brown ; diagnostic imaging ; metabolism ; Adult ; Female ; Fluorodeoxyglucose F18 ; Humans ; Positron-Emission Tomography ; methods ; Tuberculosis, Lymph Node ; diagnostic imaging

Adipose Tissue, Brown ; diagnostic imaging ; metabolism ; Adult ; Female ; Fluorodeoxyglucose F18 ; Humans ; Positron-Emission Tomography ; methods ; Tuberculosis, Lymph Node ; diagnostic imaging

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Minimally-responsive head injury survivors may have chronic catatonia reversed years after an accident.

Joseph Martin ALISKY

Singapore medical journal.2009;50(11):1117-1118.


Accidents ; Benzodiazepines ; administration & dosage ; Brain Injuries ; therapy ; Craniocerebral Trauma ; therapy ; Electroconvulsive Therapy ; methods ; Fructose ; administration & dosage ; analogs & derivatives ; Humans ; Male ; Memantine ; administration & dosage ; Middle Aged ; Pilot Projects ; Pyridines ; administration & dosage ; Valproic Acid ; administration & dosage

Accidents ; Benzodiazepines ; administration & dosage ; Brain Injuries ; therapy ; Craniocerebral Trauma ; therapy ; Electroconvulsive Therapy ; methods ; Fructose ; administration & dosage ; analogs & derivatives ; Humans ; Male ; Memantine ; administration & dosage ; Middle Aged ; Pilot Projects ; Pyridines ; administration & dosage ; Valproic Acid ; administration & dosage

Country

Singapore

Publisher

ElectronicLinks

Editor-in-chief

E-mail

Abbreviation

Singapore medical journal

Vernacular Journal Title

ISSN

0037-5675

EISSN

Year Approved

2008

Current Indexing Status

Currently Indexed

Start Year

1960

Description

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