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CSI:New Factor for Marketing Competition of Pharmaceutical Enterprises

China Pharmacy.1991;0(01):-.

OBJECTIVE:To study the new factor for marketing competition of pharmaceutical enterprises-CSI.METHO_DS:Analysis was based on the domestic and foreign documents,and combined with the actual situations of pharmaceutical enterprises in China.RESULTS & CONCLUSIONS:Only by increasing the level of CSI and establishing the CS ideas,do the medical enterprises succeed in the furiously competitive market.

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The Spot Break for Technical Skipping in Pharmaceutical Industry of China

Ying WANG

China Pharmacy.1991;0(02):-.

OBJECTIVE:To discuss about the spot break for promoting technical skipping in pharmaceutical industry of China.METHODS:Based on imbalance of technical development,matrix of technical change skipping and cluster of innovation,the necessity and possibility of the spot break for promoting technical skipping in pharmaceutical industry of China were discussed.RESULTS & CONCLUSIONS:Because the spot or part break is the normal model for promoting technical skipping in history of technical change and innovation,so if pharmaceutical industry of China wants to get technical skipping,we have to promote the spot break.In the end of this paper,the suggestions how to get spot breaks in the skipping of pharmaceutical technical change and innovation in China are put forward.

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The Challenges and Opportunities for Traditional Pharmacies in Digital Network Time

Yu LU ; Guoqiang YU ; Lianghong SI

China Pharmacy.1991;0(06):-.

OBJECTIVE: To discuss the challenges and opportunities for traditional pharmacies in digital network time. METHODS: Aiming at the problems occurring in the work of pharmacy and pharmaceutical care, we analyzed the meaning and deep impact of the using of network information technology in pharmacy .RESULTS: It is clear that the drug supply ori- ented pharmacies should be transformed to pharmaceutical care oriented pharmacies. It is very important to use computer high text to handle pharmaceutical information efficiently.CONCLUSION: The digital networks can extend the work of pharma- ceutical care in space and time and provide an opportunity to the development of pharmacies.

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Determination of the Contents of Phillyrin in Shuanghuanglian Preparations by HPLC

Dongdong NIE

China Pharmacy.1991;0(06):-.

OBJECTIVE: To establish the item of phillyrin content determination in the quality standard of shuanghuanglian preparations. METHODS:The contents of phillyrin were determined by HPLC with ODS column and acetonitrile- water(25 : 75) as mobile phase.Detecting wavelength was 277nm. RESULTS: The calibration curve was linear in this experiment. The average recovery was 99. 1% with RSD of 0. 82% .CONCLUSION: This method is good in precision and satisfactory in isolation and repeatability and the result is accurate. It may be adopted in quality control of shuanghuanglian preparations.

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Review of Adverse Reactions Induced by Quinolone Antibacterial Agents Reported During the Period 1985～1997

Zhiling DAI ; Minxiong ZHANG

China Pharmacy.1991;0(06):-.

OBJECTIVE: To properly evaluate the conditions of clinical practice of quinolone antibacterial agents. To provide data for clinical medicine and to guide rational drug use. METHODS: 237 cases with adverse reactions induced by quinolone antibacterial agents reported in demestic literatures issued from 1985 to 1997 were collected and statistically ana- lyzed. RESULTS: The general rule and characteristics of occurrence of adverse reactions resulted from quinolones have been summarized. CONCLUSION: The indications for clinical use of quinolones should be handled strictly, especially in children, so as to avoid the abuse of drug.

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Preliminary Summary of a Cooperative-study on Treatment of Hypertension With Domestic Urapidil: Re- port of 41 Cases in Clinical Trial

Guohua WAN ; Hanquan RUAN ; Yingxin PENG ; Yue XIA ; Zhiqin GUO ; Jian GU ; Shuren LI ; Yanli ZHAO ; Xue XU ; Junfang RONG ; Shuhui ZHANG

China Pharmacy.1991;0(06):-.

OBJECTIVE: To verify the therapeutic effect and adverse reactions of ?-receptor blocker, domestic urapidil, on severe hypertension. METHODS: Observation was carried out in a multi-center, random sampling and controlled pattern. Drug was iv injected first and then infused. At the same time, the patients' systolic pressure, diastolic pressure, heart rate, EKG, blood & urine routine, serum GPT and urea nitrogen were measured and examined.RESULTS: Of 41 cases in this series. 16 satis- factory(39.0%), 23 improved (56.1%), 2 unsatisfactory(4.9%) .The total effective rate was 95.1%. After drug administra- tion, systolic pressure was lowered by 43 .97mmHg(P

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Survey of Rational Drug Use for Twenty Diseases

Xiaoling LIAO ; Zhiyao ZHANG ; Jiping FAN ; Haiying LI

China Pharmacy.1991;0(06):-.

OBJECTIVE: To understand the current situation of clinical drug use and to inspect the rationality of drug use and survey indices. METHODS: Twenty common diseases(1 530 cases ) treated in this hospital in 1995 were selected. Patierits were divided into three groups according to the sources of expenses: free of charge, self - expense, public - expense or into cases of internal medical and surgical departments. Using selected drug use indicators(SDUI) and self - designed indices, clinical drug use were surveyed and analyzed. RESULTS: There were no significant differences between each group jn main indices. It showed that irrational drug use was only different in degree. CONCLUSION: ①The indices adopted are practicable and rational for surveying and studying the rational drug use objectively. ②In any health care system and in any disease, the irrational drug use was serious.

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Pharmacokinetics of Etimicin in Patients with Respiratory Tract Infections

Yuqin YIN ; Donglin ZHANG ; Keping DENG ; Guili XU ; Jing ZOU

China Pharmacy.1991;0(06):-.

OBJECTIVE: To study the pharmacokinetics of infusion Etimicin in the patients with respiratory tract infec- tions. METHODS: Ten patients were infused with 200mg Etimicin and the concentrations of drug in the plasma, urine and sputurn were determined by microbiological method. RESULTS & CONCLUSlON: The peak concentration of plasma was 17.74?g/ml. The concentration of 0.29?g/ml maintained 12h after administration. Pharmacokinetics parameters conformed to two - compartment model. The pharmacokinetics parameters were, T1/2?= 0. 257h, T1/2? = 2. 22h, Vc = 34. 32L, K2l = 2.14h~(-1), K12 = 0. 48h~(-1), K10 = 0.39h~(-1). The cumulative percentage of renal excretion was 21.37% within 12h, Ke =0. 027h~(-1), K = 0. 431h~(-1). The drug concentration in sputum reached the peak of 2.09?g/ml 2h after infusion.

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Dynamic Analysis of Botanical Injectiones Used in Partial Hospitals of Kunming Over the Past 4 Years

Yueqing LIANG

China Pharmacy.1991;0(06):-.

OBJECTIVE: To make clear and forecast the current situation and trend of botanical injectiones used in Kun- ming. METHODS: With sequencing method, the sum of money, amount of consumption and DDDs of botanical injectiones, used in three typical hospitals of Kunming from 1996 to 1999, were analyzed. RESULTS: The sum of money and DDDs increased rapidly .Compared with 1996, sum of money increased 65% and DDDs rose 37% in 1999. The sum of money, amount of con- sumption and DDDs were grouped on cardiocerebrovascular, anti-infective and antineoplastic drugs. CONCLUSION: There is market potential for botanical injectiones.

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Application of Cost - effect Analysis in Three Therapeutic Schemes for Chronic Hepatitis B

Haiyan WEI

China Pharmacy.1991;0(06):-.

AIM: To evaluate the economic effectiveness in different pharmacotherapeutic schemes for the same dis- ease. METHODS: Using pharmacoeconomical cost - effect analysis, three therapeutic schemes for chronic hepatitis B, including A, B and C schemes, were compared. RESULTS: B was the best scheme.CONCLUSION: The results show that pharmacoeco- nomics is very important in optimizing therapeutic schemes, guiding rational drug use and increasing economic effectiveness.

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