Journal Detail Information

1

Cite

Share

Observation of the Therapeutic Effect of Limaixian on Genitourinary Infections

China Pharmacy.2001;12(3):165-.

AIM:To evaluate the therapeutic effect of limaixian on genitourinary infections.METHODS:98 cases of genitourinary infections were randomly divided into 3 groups:treatment group,limaixian 250mg bid;control group A,roxithromycin 150 mg bid;control group B,amoxicillin 500mg tid.The therapeutic courses of 3 groups were 7 days.RESULTS:The total effective rate,pathogenic microbe clearance and adverse drug reactions(ADRs) in treatment group were 82.86％ ,81.82％ and 2.86％ respectively.The results were better than those in control group A and B.CONCLUSION:Limaixian is satisfactory in effect,mild in ADRs and broad in antimicrobial spectrum for treatment of genitourinary infections.It is worth extending.

2

Cite

Share

Observation on the Qualities of Ceftazidime for Injection Produced by Five Domestic and Foreign Pharmaceutical Factories

Jieping ZHANG ; Wenmin LI ; Chenggang WANG ; Qinyun PAN ; Junqiu WANG ; Sicheng YANG ; Li YU

China Pharmacy.2001;12(3):174-176.

OBJECTIVE： To compare the quality of ceftazidime for injection among the domestic and imported products METHODS： The ceftazidime was observed and determined with respect to the property， color and clarity of the solution， insoluble particle， content of pyridine， polymer of ceftazidime and marked content of ceftazidime RESULTS： There were some differences in above－ mentioned parameters among products of different factories， however， the parameters were within the range of standard CONCLUSION： The quality of domestic products is reliable and comparable to that of imported ones

3

Cite

Share

The Determination of Hydroxycamptothecinum and Camptothecinum by HPLC

Jinxin MA ; Zhongbao SUN ; Caiqin PENG ; Lie MA

China Pharmacy.2001;12(3):172-173.

OBJECTIVE： To establish a HPLC assay for the determination of hydroxycamptothecinum and camptothecinum.METHODS： The concentrations of hydroxycamptothecinum and camptothecinum were assayed on a C18 column with a mobile phase consisting of methanol－ water(45∶ 55) at a flow rate of 1.0 ml/min,and detected at 266nm.RESULTS： The mean recovery of hydroxycamptothecinum was 100.2％ ,the 2,4,8 hours precision RSD were less than 1.8％ ;The mean recovery of camptothecinum was 99.7％ ,the 2,4,8 hours precision RSD were less than 2.0％ .CONCLUSION： The HPLC method for determination of hydroxycamptothecinum and camptothecinum was rapid,sensitive and accurate.

4

Cite

Share

Comparison of Dissolubility of Lansoprazole Enteric－ coated Tablets With That of Enteric－ coated Capsules

Xiaoyun ZENG ; Ruochun ZHENG ; Jingbo ZHUANG ; Song XIAO ; Lijian LUO

China Pharmacy.2001;12(3):171-172.

OBJECTIVE： To study the method of measuring the in vitro dissolubility of lansoprazole enteric－ coated tablets and to find out the difference between the dissolubility of lansoprazole enteric－ coated tablets and that of lansoprazole enteric－ coated capsules.METHODS： To establish a measuring method of the dissolubility of lansoprazole enteric－ coated tablets and compare the dissolubility of lansoprazole enteric－ coated tablets with that of lansoprazole enteric－ coated capsules and to acquire the dissolving parameters for variance analysis.RESULTS： (1)The accumulative dissolving quantity of the both preparations exceeded 80％ in 30 minutes.(2)The comparison of Weibull parameters,T50,Td and m,between each other in group A showed no significant differences(P>0.05).It was the same for those of group B.(3)The parameters,T50 and Td,of group A,in comparison with those of group B,showed significant differences(P<0.001).The times needed for dissoiving 50％ and 63.2％ of quantity in group B were both shorter than those in group A.The m parameters in different groups had no significant differences(P>0.05).There was no significant difference in slope of equation between two groups.CONCLUSION： This measuring method of the in vitro dissolubility of lansoprazole enteric－ coated tablets is simple,convenient,accurate,stable,feasible and good in repetition.It is concluded that there is significant difference between the dissolubility of the two dosage forms of enteric－ coated preparation of lansoprazole.

5

Cite

Share

The Progress in the Application,Production and Marketing of Trimethoprim

Lun ZHANG

China Pharmacy.2001;12(3):142-144.

AIM： To probe into the future development of trimethoprim in China.METHODS： To describe the latest development in the production and application of trimethoprim and to analyse the market situation.RESULTS ＆ CONCLUSION： We consider that the production of trimethoprim in China has considerable basis and we should pay attention to marketing changes

6

Cite

Share

Thinking About Trademark Protection of Traditional Chinese Medicine After WTO Entry

Shu WANG ; Wenzhan YANG ; Lihua SUN

China Pharmacy.2001;12(3):142-143.

OBJECTIVE： To investigate the methods for protecting trademark of traditional Chinese medicine after WTO entry.METHODS： Analysis was based on the trademark laws at home and abroad in combination with the current situations of trademark protection of traditional Chinese medicine in China.RESULTS ＆ CONCLUSION： We put forward and discuss some issues that attention should be paid to the trademark protection of traditional Chinese medicine as well as ways to deal with them.

7

Cite

Share

On the Development and Edification of Canadian Guidelines for the Pharmacoeconomic Evaluation

Ni ZHANG ; Jinxin CHEN ; Hualin SONG ; Li SHENG

China Pharmacy.2001;12(3):138-140.

AIM:To put forward the suggestions for standardizing the pharmacoeconomic research.METHODS:The background of formulation and main points of Canadian Guidelines for the Pharmacoeconomic Evaluation were introduced and its recent development was described.At the same time,we put forward our tentative plan about establishing Chinese guidelines for the pharmacoeconomic evaluation.RESULTS ＆ CONCLUSION:A series of guidelines for the pharmacoeconomic evaluation should be established,which is approved by departments of social safeguard,drug supervision and public health administration,to standardize the pharmacoeconomic research.The goverment should make corresponding policy publicized and make pharmacoeconomic evaluation connect with drug price,clinically rational drug use,catalog of classified management of drugs and catalog of drugs in medical insurance.A pharmacoeconomic framework,which conforms China's national conditions and is controlled by goverment,will established.

8

Cite

Share

Outline of Legal System of Public Bidding and Purchasing Drugs by Centralized Bidding

Gong LU

China Pharmacy.2001;12(3):136-137.

OBJECTIVE:To provide legal basis for purchasing drugs by centralized bidding.METHODS:On the basis of the relevant laws,to expound the process of purchasing drugs by centralized bidding and the standards that should be observed. RESULTS ＆ CONCLUSION:Purchasing drugs by centralized bidding should observe the public bidding law of the People's Republic of China,only by observing the law can it benefits the nation and the people.

9

Cite

Share

Determination of the contents of Puerarin in Qingshangqitong Capsule

Yuchun HUANG ; Tongfang DU

China Pharmacy.2001;12(3):169-170.

OBJECTIVE： To determine the contents of puerarin in Qingshangqitong capsule.METHODS： TLC was used with detecting wavelength 260nm and reference wavelength 370nm.RESULTS： The average recovery was 98.43％ with a RSD of 1.45％ .CONCLUSION： This method is simple and accurate,and can be used as a quality control parameter of this preparation.

10

Cite

Share

Analysis of 50 Cases of Severe Liver Function Damage Induced by Antituberculotics

Jinhai FENG ; Tongzhu WU

China Pharmacy.2001;12(3):168-169.

OBJECTIVE： To discuss the severe liver function damage induced by antituberculostics.METHODS： The severe liver function damage induced by antituberculotis was analyzed in 50 patients admitted into this hospital from January 1995 to January 2000.RESULTS： Sever liver function damage was related to the following factors:(1)history of liver diseases;(2)aged patient and malnutritional patient;(3)chronic alcoholism;(4)combined use of isoniazid,rifampin with other drugs;(5)hepatic dysfunction before treatment.CONCLUSION： The abovementioned factors should be under consideration in choice of antituberculotics.

DISPLAY OPTIONS

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share

Cite

Share