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Conflict of Interest.

Soo Young KIM

Korean Journal of Family Medicine.2012;33(3):125-125. doi:10.4082/kjfm.2012.33.3.125

No abstract available.
Conflict of Interest

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Validity of Alcohol Use Disorder Identification Test: Methodological Issues.

Siamak SABOUR

Korean Journal of Family Medicine.2017;38(2):106-107. doi:10.4082/kjfm.2017.38.2.106

No abstract available.
Alcohol Drinking ; Alcohol-Related Disorders ; Alcohols ; Diagnostic and Statistical Manual of Mental Disorders ; Reproducibility of Results ; Sensitivity and Specificity ; Surveys and Questionnaires

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A Diagnosis to Consider in an Adult Patient with Facial Features and Intellectual Disability: Williams Syndrome.

Ozlem Akgün DOĞAN ; Pelin Ozlem ŞIMŞEK KIPER ; Gülen Eda UTINE ; Mehmet ALIKAŞIFOĞLU ; Koray BODUROĞLU

Korean Journal of Family Medicine.2017;38(2):102-105. doi:10.4082/kjfm.2017.38.2.102

Williams syndrome (OMIM #194050) is a rare, well-recognized, multisystemic genetic condition affecting approximately 1/7,500 individuals. There are no marked regional differences in the incidence of Williams syndrome. The syndrome is caused by a hemizygous deletion of approximately 28 genes, including ELN on chromosome 7q11.2. Prenatal-onset growth retardation, distinct facial appearance, cardiovascular abnormalities, and unique hypersocial behavior are among the most common clinical features. Here, we report the case of a patient referred to us with distinct facial features and intellectual disability, who was diagnosed with Williams syndrome at the age of 37 years. Our aim is to increase awareness regarding the diagnostic features and complications of this recognizable syndrome among adult health care providers. Williams syndrome is usually diagnosed during infancy or childhood, but in the absence of classical findings, such as cardiovascular anomalies, hypercalcemia, and cognitive impairment, the diagnosis could be delayed. Due to the multisystemic and progressive nature of the syndrome, accurate diagnosis is critical for appropriate care and screening for the associated morbidities that may affect the patient's health and well-being.
Adult* ; Cardiovascular Abnormalities ; Cognition Disorders ; Diagnosis* ; Health Personnel ; Humans ; Hypercalcemia ; Incidence ; Intellectual Disability* ; Mass Screening ; Williams Syndrome*

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Confusion, Faciobrachial Dystonic Seizures, and Critical Hyponatremia in a Patient with Voltage-Gated Potassium Channel Encephalitis.

Julian YAXLEY

Korean Journal of Family Medicine.2017;38(2):99-101. doi:10.4082/kjfm.2017.38.2.99

Autoimmune limbic encephalitis is a rare cause of encephalitic disease. It is associated with various target antigens and is difficult to diagnose, and experience with its treatment is limited. This case report describes a 69-year-old man, who presented with life-threatening hyponatremia and confusion, following several months of gradually worsening faciobrachial dystonic seizures. Faciobrachial dystonic seizures are a well-described feature classically observed in voltage-gated potassium channel autoimmune encephalitis. The presence of chronic hyponatremia without cognitive dysfunction, eventually culminating in an acute episode of encephalopathy and severe hyponatremia, is a pattern of natural history not previously documented in this condition.
Aged ; Brain Diseases ; Dystonia ; Encephalitis* ; Humans ; Hyponatremia* ; Limbic Encephalitis ; Natural History ; Potassium Channels, Voltage-Gated* ; Seizures*

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Relationship Between Alcohol Consumption and Prostatic Hyperplasia According to Facial Flushing After Drinking in Korean Men.

Hak Sun JANG ; Jong Sung KIM ; Sung Soo KIM ; Jin Gyu JUNG ; Seok Joon YOON ; HyunJu YANG ; Hyun Chul JOUNG

Korean Journal of Family Medicine.2017;38(2):93-98. doi:10.4082/kjfm.2017.38.2.93

BACKGROUND: The purpose of this study was to examine whether facial flushing after drinking influences the relationship between alcohol consumption and prostatic hyperplasia among Korean men. METHODS: The subjects were 957 Korean men (180 non-drinkers, 389 with drinking-related facial flushing, 388 without facial flushing) in the 40–69 age group, who underwent prostate ultrasound at the health promotion center of Chungnam National University Hospital between 2008 and 2014. Alcohol consumption and alcohol-related facial flushing were assessed through a questionnaire. In terms of the amount consumed, 14 g of alcohol was considered a standard drink. With the non-drinker group as reference, logistic regression was used to analyze the relationship between weekly alcohol intake and prostatic hyperplasia in the flushing and non-flushing groups, with adjustment for confounding factors such as age, body mass index, smoking, and exercise patterns. RESULTS: Individuals aged 50–59 years who experienced drinking-related facial flushing had a significantly lower risk of prostatic hyperplasia than the non-drinker group, depending on alcohol consumption: ≤4 standard drinks (adjusted odds ratio [OR], 0.38; 95% confidence interval [CI], 0.16 to 0.86); >4 ≤8 standard drinks (OR, 0.35; 95% CI, 0.13 to 0.95); >8 standard drinks (OR, 0.33; 95% CI, 0.13 to 0.84). However, no significant relationship was observed between the number of drinks consumed and the risk of prostate hyperplasia in the non-flushing group. CONCLUSION: The risk of prostatic hyperplasia appears to be reduced by alcohol consumption among Korean men aged 50–59 years who exhibit drinking-related facial flushing.
Alcohol Drinking* ; Alcohols ; Body Mass Index ; Chungcheongnam-do ; Drinking* ; Flushing* ; Health Promotion ; Humans ; Hyperplasia ; Logistic Models ; Male ; Odds Ratio ; Prostate ; Prostatic Hyperplasia* ; Smoke ; Smoking ; Ultrasonography

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The Association Between Shift Work and Health Behavior: Findings from the Korean National Health and Nutrition Examination Survey.

Myung Ji BAE ; Yun Mi SONG ; Jin Young SHIN ; Bo Young CHOI ; Jung Hyun KEUM ; Eun Ae LEE

Korean Journal of Family Medicine.2017;38(2):86-92. doi:10.4082/kjfm.2017.38.2.86

BACKGROUND: Shift workers are increasing worldwide, and various negative health effects of shift work have been reported. This study aimed to evaluate the relationship between shift work and health behavior. METHODS: This cross-sectional study included a total of 11,680 Korean adults (6,061 men and 5,619 women) aged ≥20 years old who participated in the Fifth Korean National Health and Nutrition Examination Survey, 2010–2012. Multiple logistic regression analysis was performed to evaluate the association between shift work and health behavior after adjusting for covariates. RESULTS: In men, shift work was associated with an increased risk of inadequate sleep (odds ratio [OR], 1.18; 95% confidence interval [CI], 1.00 to 1.40) compared to day work. In women, shift work was associated with an increased risk of smoking (OR, 1.73; 95% CI, 1.34 to 2.22) and inadequate sleep (OR, 1.24; 95% CI, 1.05 to 1.47) compared to day work. In an age-stratified subgroup analysis, female shift workers aged ≥50 years old demonstrated an increased risk of smoking (OR, 5.55; 95% CI, 3.60 to 8.55), alcohol consumption (OR, 2.22; 95% CI, 1.53 to 3.23), and inadequate sleep (OR, 1.50; 95% CI, 1.10 to 2.05) compared to female day workers. CONCLUSION: Shift work is associated with worse health behavior, and this is most evident in women aged ≥50 years. Targeted strategies to reduce the negative health effects of shift work should be implemented, with consideration of shift workers' demographic characteristics.
Adult ; Alcohol Drinking ; Alcoholism ; Cross-Sectional Studies ; Female ; Health Behavior* ; Humans ; Logistic Models ; Male ; Nutrition Surveys* ; Sleep Wake Disorders ; Smoke ; Smoking ; Work Schedule Tolerance

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Association Between Serum 25-Hydroxyvitamin D Levels and Dry Eye in Korean Adults: A Study Based on Korean National Health and Nutrition Examination Survey, 2010–2011.

Min Ji KIM ; Hye Rim HWANG ; Yun Jin KIM ; Sang Yeoup LEE ; Jeong Gyu LEE ; Dong Wook JEONG ; Yun Hee KIM

Korean Journal of Family Medicine.2017;38(2):81-85. doi:10.4082/kjfm.2017.38.2.81

BACKGROUND: Dry eye is a common disease. Many patients continue to experience residual symptoms despite optimal treatment. Thus, new treatment options are required. The purpose of this study was to evaluate the association between serum 25-hydroxyvitamin D [25(OH)D] levels and dry eye. METHODS: This study was performed using data from the fifth Korean National Health and Nutrition Examination Survey, which is a cross-sectional study of the Korean population that was conducted from 2010 to 2011. We included adults aged >19 years who underwent ophthalmologic interviews and examinations. We excluded subjects who had comorbid conditions (rheumatoid arthritis, thyroid disease, chronic kidney disease, or depression) that are associated with dry eye. The subjects were divided into normal and dry eye groups. The dry eye group consisted of those who had clinically diagnosed dry eye syndrome or symptoms. Multiple logistic regression analysis was conducted to determine the association between serum 25(OH)D levels and dry eye. RESULTS: In the univariate model, the 25(OH)D levels were lower in the dry eye group than in the normal group (P=0.01). A significant association was found between severe vitamin D deficiency (<10 ng/mL) and dry eye (P=0.04). However, after multivariate adjustment, the statistical significance of the association disappeared (P-values= 0.49, vitamin D insufficiency; P=0.33, vitamin D deficiency; P=0.18, severe vitamin D deficiency). CONCLUSION: Severe vitamin D deficiency was associated with dry eye in an unadjusted model, but the association was not statistically significant after adjustment.
Adult* ; Arthritis ; Cross-Sectional Studies ; Dry Eye Syndromes ; Humans ; Logistic Models ; Nutrition Surveys* ; Renal Insufficiency, Chronic ; Thyroid Diseases ; Vitamin D ; Vitamin D Deficiency

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Joint Effect of Cigarette Smoking and Body Mass Index on White Blood Cell Count in Korean Adults.

A Ra CHO ; Won Jun CHOI ; Shin Hye KIM ; Jae Yong SHIM ; Yong Jae LEE

Korean Journal of Family Medicine.2017;38(2):75-80. doi:10.4082/kjfm.2017.38.2.75

BACKGROUND: White blood cell count is an independent risk factor for cardiovascular disease. Several lifestyle and metabolic factors such as cigarette smoking and obesity are known to be associated with an elevated white blood cell count. However, the joint effect of cigarette smoking and obesity on white blood cell count has not yet been fully described. METHODS: We explored the joint effect of cigarette smoking and obesity on white blood cell count using multiple logistic regression analyses after adjusting for confounding variables in a population-based, cross-sectional study of 416,065 Korean adults. RESULTS: Cigarette smoking and body mass index have a dose-response relationship with a higher white blood cell count, but no synergistic interaction is observed between them (men, P for interaction=0.797; women, P for interaction=0.311). Cigarette smoking and body mass index might have an additive combination effect on high white blood cell count. Obese male smokers were 2.36 times more likely and obese female smokers 2.35 times more likely to have a high white blood cell count when compared with normal body mass index non-smokers. CONCLUSION: Cigarette smoking and body mass index are independently associated with an elevated white blood cell count in both men and women.
Adult* ; Body Mass Index* ; Cardiovascular Diseases ; Confounding Factors (Epidemiology) ; Cross-Sectional Studies ; Female ; Humans ; Joints* ; Leukocyte Count* ; Leukocytes* ; Life Style ; Logistic Models ; Male ; Obesity ; Risk Factors ; Smoking* ; Tobacco Products*

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Association Between the Awareness of Dyslipidemia and Health Behavior for Control of Lipid Levels Among Korean Adults with Dyslipidemia.

In Young CHO ; Hwa Yeon PARK ; Kiheon LEE ; Woo Kyung BAE ; Se Young JUNG ; Hye Jin JU ; Jae Kyeong SONG ; Jong Soo HAN

Korean Journal of Family Medicine.2017;38(2):64-74. doi:10.4082/kjfm.2017.38.2.64

BACKGROUND: Dyslipidemia is a major risk factor contributing to cardiovascular disease and its prevalence is steadily rising. Although screening tests are readily accessible, dyslipidemia remains undertreated. Evaluating health behavior patterns after diagnosis may help improve lifestyle interventions for the management of dyslipidemia. METHODS: Data from the fifth Korean National Health and Nutrition Examination Survey 2010–2012 were used. A total of 6,624 dyslipidemia patients over 20 years old were included according to National Cholesterol Education Program-Adult Treatment Panel III guidelines. Logistic regression analysis was completed using a weighted method to determine whether awareness of dyslipidemia was associated with health behavior. Health behavior was divided into two categories: behavioral factors (smoking, alcohol consumption, exercise) and nutritional factors (adequate intake of fiber, carbohydrate, fat, protein). RESULTS: There were no significant differences in health behavior among dyslipidemia patients according to awareness after adjustment for covariates, diabetes and hypertension. Awareness in women was associated with decreased smoking (odds ratio [OR], 0.55; 95% confidence interval [CI], 0.32 to 0.94), but when adjusted for diabetes and hypertension the result was not significant (OR, 0.61; 95% CI, 0.35 to 1.06). The same pattern applied to intake of carbohydrate in men (OR, 1.28; 95% CI, 0.99 to 1.67) and protein in women (OR, 1.22; 95% CI, 0.98 to 1.50). In subgroup analysis, awareness of dyslipidemia in men without hypertension or diabetes was associated with adequate intake of carbohydrate (OR, 1.70; 95% CI, 1.06 to 2.72). CONCLUSION: Increasing awareness alone may not be enough to improve healthy behavior in patients with dyslipidemia. Efforts including patient education and counseling through a multi-team approach may be required.
Adult* ; Alcohol Drinking ; Cardiovascular Diseases ; Cholesterol ; Counseling ; Diagnosis ; Dyslipidemias* ; Education ; Female ; Health Behavior* ; Humans ; Hypertension ; Life Style ; Logistic Models ; Male ; Mass Screening ; Methods ; Nutrition Surveys ; Patient Education as Topic ; Prevalence ; Risk Factors ; Smoke ; Smoking

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Mental Health of the People with Hearing Impairment in Korea: A Population-Based Cross-Sectional Study.

Hyun Young SHIN ; Hee Jin HWANG

Korean Journal of Family Medicine.2017;38(2):57-63. doi:10.4082/kjfm.2017.38.2.57

BACKGROUND: The prevalence of hearing impairment is increasing and an association between hearing impairment and mental health has been reported. Our study aimed to determine the association between hearing impairment and mental health in Korea. METHODS: This was a cross-sectional study of data from the Korean National Health and Nutrition Examination Survey 2010–2013, with a sample size of 18,563 individuals (6,395 with hearing impairment and 12,168 without hearing impairment), aged ≥20 years. RESULTS: The female group with hearing impairment tended to have a higher rate of stress (odds ratio [OR], 1.32; 95% confidence interval [CI], 1.11 to 1.56). The association between hearing impairment and depressive symptoms was higher in elderly males (OR, 1.60; 95% CI, 1.10 to 2.32), while the association of hearing impairment with suicide ideation was higher in elderly females (OR, 1.32; 95% CI, 1.00 to 1.75). CONCLUSION: Elderly individuals with hearing impairment are easily susceptible to poor mental health status. Early targeted intervention to address mental health problems is recommended for people with hearing impairment.
Aged ; Cross-Sectional Studies* ; Depression ; Female ; Hearing Loss* ; Hearing* ; Humans ; Korea* ; Male ; Mental Health* ; Nutrition Surveys ; Prevalence ; Sample Size ; Suicide

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