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Conservative infection control on acute pericoronitis in mandibular third molar patients referred from the prison.

Chun Ui LEE ; Jae Ha YOO ; Byung Ho CHOI ; Sung Han SUL ; Ha Rang KIM ; Dong Yub MO ; Jong Bae KIM

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):57-61. doi:10.5125/jkaoms.2010.36.1.57

In the presence of acute pericoronitis of mandilbular third molar, antibiotic therapy and early incision and drainage are the method of choice, followed by definitive surgical extraction of the tooth as soon as it becomes subacute. If excision of the overlying tissues is decided on, it should be done adequately. All overlying tissues must be throughly excised, and the crown portion of the unerupted tooth should be completely exposed. After excision has been completed, the wound should be managed with a surgical dressing. This should be allowed to remain approximately 7 days. And then, surgical extraction of the impacted mandibular third molar can be done usually. In this operation, there are many complications, such as, postoperative bleeding, infection, trismus, dysphasia and paresthesia. The surgeon are discredited and medicolegal problem may be occurred in the presence of many distressed complications. Therefore, the relatively nonsurgical treatment is the method of choice. So, authors selected the conservative treatment methods of incision and drainage, primary endodontic drainage, operculectomy without surgical extraction of the mandibular third molars. The results were more favorable without the postoperative complication in Wonju old offender prison.
Aphasia ; Bandages ; Criminals ; Crowns ; Drainage ; Hemorrhage ; Humans ; Infection Control ; Molar, Third ; Paresthesia ; Pericoronitis ; Postoperative Complications ; Prisoners ; Prisons ; Tooth ; Tooth, Unerupted ; Trismus

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Carcinoma ex pleomorphic adenoma of the parotid gland: Case report.

Jin Hwan JUNG ; Sang Chil LEE ; Dong Woo KIM ; Dae Song PARK ; Seul Ki LEE ; Chul Hui PARK ; Hak Ryul YEOM ; Hyeon Min KIM ; Min Seok SONG

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):53-56. doi:10.5125/jkaoms.2010.36.1.53

Carcinoma ex pleomorphic adenoma is transformed at the incidence of 1-20% in pleomorphic adenoma and frequently recurred. It accounts for 10% of all malignant salivary tumors and its average age of occurrence is 60s. It will present in a large, long-standing pleomorphic adenoma or in one that was previously treated but has recurred. According to cell composition in malignant cell carcinoma, and clear cell adenocarcinoma. Most (75%) occur in parotid gland, while about 20% occur in the minor gland of the oral mucosa. The metastasis rate to regional lymph node is about 25%, and to distant organs about 33% and the 5-year survival rates are 40%. Though the treatment of the carcinoma ex pleomorphic adenoma is not established, it is treated ideally with and extensive resection, neck dissection, postoperative radiotherapy, and chemotherapy. When occurred in parotid gland, facial paralysis is reported. With a review of literatures, we report a case of carcinoma ex pleomorphic adenoma which operated with total parotidectomy and supraomohyoid neck dissection.
Adenocarcinoma, Clear Cell ; Adenoma, Pleomorphic ; Incidence ; Lymph Nodes ; Mouth Mucosa ; Neck Dissection ; Neoplasm Metastasis ; Parotid Gland ; Survival Rate

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Clinical study of maxillofacial trauma of children.

Hak Ryeol KIM ; Yeo Gab KIM

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):43-52. doi:10.5125/jkaoms.2010.36.1.43

PURPOSE: To research about maxillofacial traumatic injuries of children in aspects of gender difference, various incidence rates between age, trauma type, cause, monthly and daily incidence rate, type of tooth damage, gingival damage, soft tissue damage, and type of facial bone fracture. MATERIALS AND METHODS: Study group consisted of children under 15 years of age who visited Dental Hospital, School of Dentistry, Kyung Hee University from 2004/7/1 to 2007/6/30 with chief complaint of oral and maxillofacial traumatic injuries. 1,559 cases of traumatic injuries were studied from 1,556 (1,004 male, 552 female) children. CONCLUSION: 1. There were slightly more boys than girls, giving a male-to-female ratio of 1.82:1.0. The 1-3 year old boys and girls had the highest number of traumatic injuries. 2. Of the 1,556 patients, 68.63% had soft tissue injuries, 50.22% had periodontal injuries, 29.89% had teeth injuries, and 3.85% had maxillofacial bone fractures. 3. Falling down was the most common cause of injury in both sexes. 4. The months with the highest incidence rates were in order May (12.12%), June (11.74%), and October (11.13%). Most of the injuries occurred on weekends. 5. The most common tooth injury was uncomplicated crown fracture, and the most common periodontal injury was subluxation. The majority of traumatizes teeth were the upper central incisors. 6. The most common soft tissue injury was intraoral lacerations. 7. Mandibular fractures were most frequent in facial bone fractures; symphysis, condylar head, and angle fractures were most frequent in mandibular fractures; maxillary and nasal bone fractures were most frequent in midfacial bone fractures.
Child ; Crowns ; Dentistry ; Facial Bones ; Fractures, Bone ; Head ; Humans ; Incidence ; Male ; Mandibular Fractures ; Maxillofacial Injuries ; Nasal Bone ; Soft Tissue Injuries ; Tooth ; Tooth Injuries

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Effect of bovine bone (Bio-Oss(R)) and platelet rich plasma, platelet poor plasma on sinus bone graft in rabbit.

Tai Hyung LEE ; You Min JEONG ; Yong Kun CHOI ; Eui Seok LEE ; Hyon Seok JANG ; Jae Suk RIM

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):39-42. doi:10.5125/jkaoms.2010.36.1.39

Maxillary sinus lift and bone graft are used to reconstruct atrophic maxilla molar area for endosseous dental implants. Many different grafting materials and techniques can be used for maxillary sinus bone graft. Bio-Oss(R) has been proposed as bone substitute and successfully utilized as osteoconductive filler. Platelet rich plasma (PRP) is an autologous material with many growth factors, such as PDGF, TGF-beta, IGF, VEGF, facilitating bone healing process. And Platelet poor plasma (PPP) is the by-product in procedure of producing PRP. Six rabbits were used as experimental animal. Both maxillary sinus were grafted with Bio-Oss(R) and PRP, and Bio-Oss(R) and PPP. Rabbits were sacrificed at 4, 8 and 12 weeks. The grafting sites were evaluated by histomorphometric analysis. As a result, using PRP showed excellent bone formation in the early stage, but no further significant effect after that. In late stage, the ability of bone formation of using PRP was even worse than using PPP. The further studies need to be considered in this case.
Animals ; Blood Platelets ; Bone Substitutes ; Dental Implants ; Intercellular Signaling Peptides and Proteins ; Maxilla ; Maxillary Sinus ; Molar ; Osteogenesis ; Plasma ; Platelet-Rich Plasma ; Rabbits ; Transforming Growth Factor beta ; Transplants ; Vascular Endothelial Growth Factor A

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Clinical analysis of early reoperation cases after orthognathic surgery.

Ju Hwan LEE ; In Woo LEE ; Byoung Moo SEO

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):28-38. doi:10.5125/jkaoms.2010.36.1.28

The factors influencing the relapse and recurrence of skeletal deformity after the orthognathic surgery include various factors such as condylar deviation, the amount of mandibular set-back, stretching force by the soft tissues and muscles around the facial skeleton. The purpose of this report is to recognize and analyze the possible factors of reoperation after orthognathic surgery, due to early relapses. Six patients underwent reoperation after the orthognathic surgeries out of 110 patients from 2006 to 2009 were included in this study. In most cases, clincal signs of the insufficient occlusal stability, anterior open bite, and unilateral shifting of the mandible were founded within 2 weeks postoperatively. Although elastic traction was initiated in every case, inadequate correction made reoperation for these cases inevitable. The chief complaints of five cases were the protruded mandible combined with some degree of asymmetric face and in the other one case, it was asymmetric face only. Various factors were considered as a major cause of post-operative instability such as condylar sagging, counter-clockwise rotation of the mandibular segment, soft tissue tension related with asymmetrical mandibular set-back, preoperatively existing temporomandibular disorder (TMD), poor fabrication of the final wafer, and dual bite tendency of the patients.
Bites and Stings ; Congenital Abnormalities ; Humans ; Mandible ; Muscles ; Open Bite ; Orthognathic Surgery ; Recurrence ; Reoperation ; Skeleton ; Temporomandibular Joint Disorders ; Traction

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Reliability study of 6-axis model surgery simulator for orthognathic surgery.

Jae Ho JEON ; Hyung Chul LEE ; Hyun Jin JI ; Yeong Jin JEON ; Yong Il KIM ; Woo Sung SON ; Soo Byung PARK ; Sung Sik KIM ; Dae Seok WHANG

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):23-27. doi:10.5125/jkaoms.2010.36.1.23

The purpose of this study was to evaluate the reliability of 6-axis model surgery simulator (6AMSS) for orthognathic surgery. A rectangular parallelepiped plastic block was assembled to model-mounting plate of 6AMSS. Left-right (X), anterior-posterior (Y), up-down (Z) translation and pitching (empty set X), rolling (empty set Y) and yawing (empty set Z) rotation was planned and performed using 6AMSS. The actual translation and rotation were measured with dial gauge and precisional protractor, respectively. Comparison between the planned and actual movements of plastic block for each variable were made using paired t- test. Statistical analysis for X, Y, Z, empty set X, empty set Y and empty set Z movement have shown no significant differences between planned and actual movement (P > 0.05). This indicate that model surgery performed with the aid of the 6AMSS is accurate in 3D translation and rotation. The 6AMSS is practically useful for accurate fabrication of surgical splint for orthognathic surgery.
Orthognathic Surgery ; Plastics ; Splints

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The effect of hyaluronic acid on anti-inflammatory action in mouse.

Sang Kyun KIM ; Hyung Seok LEE ; Kwang Seob BYEON ; Young Joo LEE ; Soon Min HONG ; Mee Ra CHOI ; Jun Woo PARK

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):16-22. doi:10.5125/jkaoms.2010.36.1.16

PURPOSE: The purpose of this study was not only to evaluate the relative mRNA expression of interleukin-1beta(IL-1beta), cyclooxygenase2 (COX-2) and prostaglandin E2 (PGE2) by RT-PCR analysis but to observe pattern of edema by light microscopic and electron microscope after topical apply of hyaluronic acid in inflammation-guided mouse. MATERIAL AND METHODS: Mice of this study were devided into 4 groups: Control group (no inflammation guided), Positive control (inflammation guided + vaselin apply), Protopic group (inflammation guided + protopic apply), Hyaluronic group (inflammation guided + hyaluronic acid apply). RESULTS: Hyaluronic group showed less expressions of IL-1beta, COX-2, PGE2 than those of positive control & protopic group. Hyaluronic group revealed a decreased inflammation than positive control & protopic group in Light Microscope. Hyaluronic group appeared decreased edema of ear compare to positive control & protopic group in Elecron Microscope. CONCLUSION: It was considered that hyaluronic acid has an antiinflammatory effect for intercepting the gene expression of cytokines related to inflammation.
Animals ; Cytokines ; Dinoprostone ; Ear ; Edema ; Electrons ; Gene Expression ; Hyaluronic Acid ; Inflammation ; Light ; Mice ; RNA, Messenger

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A study on differentiation potency of adult stem cells from pulp, periodontal ligament, and dental follicle to osteoblast.

Joong Kyou LEE ; Jae Hoon LEE

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):7-15. doi:10.5125/jkaoms.2010.36.1.7

Complex human tissues harbor stem cells and precursor cells, which are responsible for tissue development or repair. Recently, dental tissues such as dental pulp, periodontal ligament (PDL), dental follicle have been identified as easily accessible sources of undifferentiated cells. These tissues contain mesenchymal stem cells that can be differentiate into bone, cartilage, fat or muscle by exposing them to specific growth conditions. In this study, the authors procured the stem cell from pulp, PDL, and dental follicle and differentiate them into osteoblast and examine the bone induction capacity. Dental pulp stem cell (DPSC), periodontal ligament stem cell (PDLSC), and dental follicle precursor cell (DFPC) were obtained from human 3rd molar and cultured. Each cell was analyzed for presence of stem cell by fluorescence activated cell sorter (FACs) against CD44, CD105 and CD34, CD45. Each stem cell was cultured, expanded and grown in an osteogenic culture medium to allow formation of a layer of extracellular bone matrix. Osteogenic pathway was checked by alizarin red staining, alkaline phosphatase (ALP) activity test and RT-PCR for ALP and osteocalcin (OCN) gene expression. According to results from FACs, mesenchymal stem cell existed in pulp, PDL, and dental follicle. As culturing with bone differentiation medium, stem cells were differentiated to osteoblast like cell. Compare with stem cell from pulp, PDL and dental follicle-originated stem cell has more osteogenic effect and it was assumed that the character of donor cell was able to affect on differential potency of stem cell. From this article, we are able to verify the pulp, PDL, and dental follicle from extracted tooth, and these can be a source of osteoblast and stem cell for tissue engineering.
Adult ; Adult Stem Cells ; Alkaline Phosphatase ; Anthraquinones ; Bone Matrix ; Cartilage ; Dental Pulp ; Dental Sac ; Durapatite ; Fluorescence ; Gene Expression ; Humans ; Mesenchymal Stromal Cells ; Molar ; Muscles ; Osteoblasts ; Osteocalcin ; Periodontal Ligament ; Stem Cells ; Tissue Donors ; Tissue Engineering ; Tooth

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Stromal cell-derived factor-1 (SDF-1) expression in the oral squamous cell carcinoma.

Kyung Wook KIM ; Se Jin HAN ; Kyu Seob ROH

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2010;36(1):1-6. doi:10.5125/jkaoms.2010.36.1.1

PURPOSE: Chemokines are structurally related, small polypeptide signaling molecules that bind to and activate a family of transmembrane G proteincoupled receptors, the chemokine receptors. Recently, interaction between the chemokine receptor CXCR4 and its ligand, stromal cell-derived factor 1 (SDF-1 or CXCL12), has been found to play an important role in tumorigenicity, proliferation, metastasis and angiogenesis in many cancers such as lung cancer, breast cancer, melanoma, glioblastoma, pancreatic cancer and cholangiocarcinoma. Hence, the goal of this study is to identify the correlation of clinicopathological factors and the up-regulation of SDF-1 expression in oral squamous cell carcinoma. MATERIAL AND METHODS: We studied the immunohistochemical staining of SDF-1, quantitative RT-PCR (qRT-PCR) of SDF-1 gene in 20 specimens of 20 patients with oral squamous cell carcinoma. RESULTS: 1. In the immunohistochemical study of poor differentiated and invasive oral squamous cell carcinoma, the high level staining of SDF-1 was observed. And the correlation between immunohistochemical SDF-1 expression and tumor nodes metastases (TNM) classification of specimens was significant.(chi-square test, P < 0.05) 2. In the SDF-1 gene qRT-PCR analysis, SDF-1 expression was more in tumor tissue than in carcinoma in situ tissue. Paired-samples analysis determined the difference of SDF-1 mRNA expression level between the cancer tissue and the carcinoma in situ tissue.(Student's t-test, P < 0.05) CONCLUSION: These findings suggest that up-regulation of the SDF-1 may play a role in progression and invasion of oral squamous cell carcinoma.
Breast Neoplasms ; Carcinoma in Situ ; Carcinoma, Squamous Cell ; Chemokine CXCL12 ; Chemokines ; Cholangiocarcinoma ; Glioblastoma ; Humans ; Lung Neoplasms ; Melanoma ; Neoplasm Metastasis ; Pancreatic Neoplasms ; Receptors, Chemokine ; RNA, Messenger ; Up-Regulation

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Muscular invasion by oral squamous cell carcinoma of the posterior mandibular alveolar ridge is associated with cervical lymph node metastasis.

Seung Ki MIN ; Hoon MYOUNG ; Jong Ho LEE ; Myung Jin KIM

Journal of the Korean Association of Oral and Maxillofacial Surgeons.2016;42(3):133-138. doi:10.5125/jkaoms.2016.42.3.133

OBJECTIVES: To assess the association between muscle invasion by oral squamous cell carcinoma of the posterior mandibular alveolar ridge and cervical lymph node metastasis on the basis of preoperative magnetic resonance imaging (MRI). MATERIALS AND METHODS: Twenty-six patients with oral squamous cell carcinoma of the posterior mandibular alveolar ridge were evaluated by MRI. The associations between cervical lymph node metastasis and independent factors evaluated by MRI were analyzed. Overall survival was also analyzed in this manner. Representative biopsy specimens were stained with anti-podoplanin and anti-CD34 antibodies. RESULTS: Mylohyoid muscle invasion was associated with cervical lymph node metastasis. A combinational factor of mylohyoid and/or buccinator muscle invasion was also associated with cervical lymph node metastasis. Cervical lymph node metastasis and masticator space invasion had a negative effect on overall survival. No lymphatic vessels were identified near the tumor invasion front within the mandible. In contrast, lymphatic vessels were identified near the front of tumor invasion in the muscles. CONCLUSION: This study demonstrates an association between muscular invasion by oral squamous cell carcinoma of the posterior mandibular alveolar ridge and cervical lymph node metastasis.
Alveolar Process* ; Antibodies ; Biopsy ; Carcinoma, Squamous Cell* ; Epithelial Cells* ; Humans ; Lymph Nodes* ; Lymphatic Vessels ; Magnetic Resonance Imaging ; Mandible ; Muscles ; Neoplasm Metastasis*

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