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Journal of Audiology and Speech Pathology

2002 (v1, n1) to Present ISSN: 1671-8925

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Comparison of Diagnostic Methods of Secretory Otitis Media in Children

Yi KANG ; 上海交通大学医学院耳科学研究所 ; Jun SHI ; Yongchuan CHAI ; Weidong ZHU ; Jie YANG ; Zhaoyan WANG ; Hao WU

Journal of Audiology and Speech Pathology.2017;25(6):603-606. doi:10.3969/j.issn.1006-7299.2017.06.012

Objective To investigate the diagnostic value of endotoscopy,tympanometry,pure tone audiometry (PTA) and high resolution temporal bone CT in children with secretory otitis media (SOM).Methods The study comprised 414 ears in 207 children with adenoid hypertrophy.Endotoscopy,tympanometry,PTA and high resolution temporal bone CT were conducted to evaluate the function of middle ear.Based on the imaging findings of tympanic cavity fluid by high resolution temporal bone CT,the diagnostic accordance rate of endotoscopy,tympanograms and PTA for SOM were studied.Results The diagnostic accordance rate of endotoscopy,tympanometry and PTA for SOM were 98.79%(409/414),98.07% (406/414) and 88.41% (366/414),respectively.The sensitivity of the three examinations were 99.20%(124/125),100% (125/125),63.20% (79/125),respectively.The specificity of the three examinations were 98.62% (285/289),97.23% (281/289),99.31% (287/289),respectively.The diagnostic accordance rate of endotoscopy combined with tympanometry for SOM was significantly higher than any single examination or any combined examinations.Conclusion Endotoscopy combined with tympanometry shows a great value in diagnosing SOM,which is accurate and safe.

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Relationship between Evoked Auditory Steady-state Responses and Pure Tone Audiometry in Children with Different Levels of Hearing Loss

Chuling LI ; Shujuan TAN ; Xianglin LUO ; Yuanming WANG ; Baozhu YIN ; Renzhong LUO

Journal of Audiology and Speech Pathology.2017;25(6):591-594. doi:10.3969/j.issn.1006-7299.2017.06.009

Objective To study the clinical significance of Chirp-ASSR and the characteristics of hearing loss patients by ASSR(auditory steady-state responses) under Chirp stimulation.Methods A total of 136 hearing loss children (5~10 years old) with 272 ears were distributed into four groups based on 500 Hz,1 000 Hz,2 000 Hz and 4 000 Hz auditory threshold arithmetic average:20~dB HL,40~dB HL,60~dB HL,and≥80 dB HL groups.To compare the correlation of the PTA and Chirp-ASSR in different frequencies domain through SPSS statistics 19.0 software,the data were used T-test and Pearson analysis.Results ①The group(≥80 dB HL) achieved a statistically significant higher reaction threshold than pure tone threshold.②The correlation index γ'of PTA and Chirp-ASSR showed a decline along with the hearing loss increase;It increased along with the test frequency,there was a significant difference between 500 Hz and 4 000 Hz(P<0.05).Conclusion Chirp-ASSR is a frequency-specific electrophysiological test method,it could reflect the truthful listening ability,especially in mild,moderate,and severe hearing loss children.

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The Expression of Cav1.3 Calcium Channels in Adult Rat Cochlea

Jin CHEN ; Liangqiang ZHOU ; Hanqi CHU ; Qingguo CHEN ; Zhihui DU ; Fan QI ; Yun LIU ; Yanbo SUN ; Pengjun LI ; Dan BING

Journal of Audiology and Speech Pathology.2017;25(6):630-633. doi:10.3969/j.issn.1006-7299.2017.06.019

Objective To investigate the expression of Cav 1.3 calcium channel in adult rat cochlea and study its role in auditory physiology and pathology.Methods The sprague-dawley rats were used as experimental subjects.The distribution of Cav1.3 calcium channel in the cochlea was detected by immunofluorescence technique.The expression of Cav1.3 was measured with Western blot (WB) and RT-PCR.Results Immunofluorescence photographs revealed that Cav 1.3 calcium channel localized in the lateral wall membrane,hair cells,stria vascularis,spiral ganglion cell,spiral ligment,spiral prominence,and limbus laminae spiralis.The results of WB and RT-PCR inform Cav1.3 calcium channel gene (CACNA1D) were measured in the cochlea and kidney.The expression of Cav1.3was mainly in the basilar membrane.Moderate expression was observed in the spiral ganglion and stria vascularis.Conclusion The preliminary study revealed the distribution of Cav 1.3 calcium channel gene(CACNA1D)in adult rat cochle possesses tissue specificity,providing a theoretical basis for further research in auditory physiology and pathology.

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Use of Suspension Laryngoscopy CO2 Laser Combined with Placement of Silastic Keel for the Treatment of the Vocal Cords Adhesion

Yan WANG ; Jining QU ; Tao ZHOU ; Wei MING

Journal of Audiology and Speech Pathology.2017;25(6):623-626. doi:10.3969/j.issn.1006-7299.2017.06.017

Objective To investigate the use of suspension laryngoscopy CO2 laser combined with the placement of laryngeal stent for the treatment of the vocal cords adhesion.Methods A total of 21 patients with acquired vocal cords of adhesion patients(The causes were previous vocal fold surgery for benign lesions in 16 cases,the laryngeal surgery for recurrent papilloma in 4 cases,the laryngeal trauma in 1 case)were included in this retrospective study.Under general anesthesia with intubation,following glottis exposure under suspension laryngoscopy,a CO2 laser incision was performed under microscopy on the superior face of one vocal fold,from the anterior commissure to the posterior part of the web.The keel was placed into the larynx to the appropriate location and fixed with sutures.Results The keels were removed after 3 weeks of operation in 20 patients.The keels were removed after 2 weeks of operation because of subcutaneous emphysema in 1 patient.After a follow-up of 6 months,the reformation of the web happened in 1 case,while the remaining 20 patients recovered with normal triangle shaped anterior commissure anatomy and no granulation or scar tissue were formed.Conclusion Our study shows that the use of suspension laryngoscopy CO2 laser combined with the placement of laryngeal stent is successful for the treatment of the vocal cords adhesion.This procedure has the advantages of micro trauma to patients with avoiding laryngofissure,it provides simple effective treatment of vocal cords adhesion.

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The Analysis of the Recurrence Factors of CO2 Laser Surgery for Tis,T1 and T2 Glottic Cancer

Guanglun WAN ; Chong GE ; Jingwu SUN ; Hao CHEN ; Wan ZHAO

Journal of Audiology and Speech Pathology.2017;25(6):619-622. doi:10.3969/j.issn.1006-7299.2017.06.016

Objective To study the risk factors for recurrence in glottic cancer at Tis,T1 and T2 stage after CO2 laser endoscopic resection.Methods We conducted a retrospective analysis of 180 Tis,T1 and T2 glottic cancer cases treated by CO2 laser surgery.Of the total cases,the Tis stage lesion was found in 22 cases,the T1a in 90,the T1b in 32 and the T2 in 36 cases.Tumor recurrence was set as the time-related endpoint.The recurrence factors were analyzed by univariate and multivariate analysis,including age,gender,T classification,type of cordectomy,tumorgrading,motility of vocal fold and the possible anteior commissure.Results There was a significant statistical difference between the recurrence rate and T classification,and the type of cordectomy(P<0.05).The recurrence rates of Tis,T1a,T1b and T2 were 9.1%,13.3%,18.8% and 38.9%,respectively.In type-Ⅰ,Ⅱ,Ⅲ,Ⅳ and Ⅴ of cordectomy,the recurrence rates were 0,3.57%,15.0%,19.60% and 36.84%.Conclusion The recurrence rate is closely associated with T classification and the type of cordectomy.With the higher T classification and the type of cordectomy,the recurrence rate is dramatically higher.

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The Curative Effects of Frontal-lateral Window Partial Laryngectomy for T1b Glottic Cancinoma Invading Anterior Commissure

Zhaotang ZHONG ; Minzhi LIANG ; Ze CHEN ; Lingfei MO ; Jialu LIANG

Journal of Audiology and Speech Pathology.2017;25(6):615-618. doi:10.3969/j.issn.1006-7299.2017.06.015

Objective To explore the efficacy of reserving thyroid cartilage combined with thyroid perichondrium flap to repair the defect of frontal-lateral window partial laryngectomy for T1b glottic cancinoma with anterior commissure involved.Methods From our hospital 22 cases diagnosed as T1b glottic cancer with anterior commissure invaded were treated with frontal-lateral window partial laryngectomy and were repaired by reserving thyroid cartilage combined with flap of thyroid perichondrium.All the patients were followed up for five years.The functions of respiratory and swallowing,voice rehabilitation,ratios of recurrence and survival were observed.Results All the patients succeeded in removing tracheal cannula.The decannulation rate was100% and the aspiration rate was 0%.The voice functions in patients with postoperative classification (G) were higher than that of preoperative accounted for 86.4% (19/22),and the same preoperative accounted for 13.6% (3/22).There were 2 cases with tumor recurrence,one cases with recurrence in situ and one case with cervical lymph node metastasis.The recurrence rate was 9.1% (2/22) and the 5 year survival rate was 95.5% (21/22).Conclusion Frontal-lateral window partial laryngectomy reserving thyroid cartilage combined with thyroid perichondrium flap,is suitable for T1b glottic cancinoma invading anterior commissure.It can preserve the laryngeal framework and function relatively integrated with rare laryngeal stenosis and stabble repaired tissue.It also can effectively improve the sound quality and is worthy of clinical promotion.

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Clinical Application of Attic Obliteration in Open-Cavity Tympanoplasty

Fengming GU

Journal of Audiology and Speech Pathology.2017;25(6):627-629. doi:10.3969/j.issn.1006-7299.2017.06.018

Objective To evaluate the effect of attic obliteration in canal wall down tympanoplasty.Methods A clinical study was performed on 100 ears with chronic otitis media that underwent open-cavity operation and attic obliteration with bone pate in Department of Otology and Skull Base Surgery of Eye and ENT Hospital form January 2010 to January 2015.A pre-and post-operative pure tone air conduction (AC) and bone conduction (BC2) audiogram were obtained 6 months after the surgery.Results There were 1 case with retraction pocket formation and 5 cases with cavity infection in the postoperative follow-up of 1 year to 5 years.The mean preoperative AC threshold of 43.2±2.3 dB HL was lowered to 29.8±1.7 dB HL postoperatively (P<0.01).The mean preand post-operative air-bone gap was reduced with 10.6±0.5 dB (P<0.01).Conclusion The attic obliteration with bone pate in open-cavity tympanoplasty prevents the recurrence of cholesteatoma and improves the hearing on condition that total elimination of the lesions.

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An Application of Disyllabic MSTMs for Patients with Presbycusis

Yue WANG ; Hua ZHANG ; Zhongwei ZHENG ; Yu QI ; Jinzhe FENG ; Lingyan MO ; Huili ZHAO

Journal of Audiology and Speech Pathology.2017;25(6):557-562. doi:10.3969/j.issn.1006-7299.2017.06.001

Objective To analyze the clinical characteristics of patients with presbycusis by using disyllabic mandarin speech test materials (MSTMs).Methods A total of 59 subjects (23 men and 36 women) with presbycusis,from 61 to 84 years old with the average as 71.3±6.7.They were divided into three groups:the mild group (10 subjects),the moderate group (35 subjects)and the severe group (14 subjects)according to the pure tone average (PTA) thresholds at 0.5,1,2 and 4 kHz from the better ear.In addition,11 subjects of elderly persons with normal hearing were used as the control group.All the subjects enrolled in this study could speak Mandarin well in their daily lives.Nine lists of disyllabic mandarin speech test materials were utilized to test speech recognition threshold (SRT) and P-I function for these groups respectively.Results The PTA(51.65±11.98)and SRT (50.98±16.05)from presbycusis group were much higher than the control group(PTA 19.55± 4.55,SRT 18.79± 7.45),while the average slope of the P-I function 2.63%/dB from the presbycusis group was lower than the control group 4.65%/dB (P<0.01).The SRT of male patients (56.54±17.23) was higher than the females(47.99± 15.63) (P<0.05).The PTA and SRT in these three groups divided by degrees of hearing loss were higher than the control group obviously.The PTA and SRT had significantly increased as the degree of hearing loss increased.The differences among these groups were significant (P<0.01).The average slope of P-I function of these three groups divided by degrees of hearing loss (mild group:2.47%/dB,moderate group:2.76%/dB,severe group:2.42%/dB) was smaller than the slopes in the control group which was 4.65 %/dB (P<0.01).The average slope of P-I function among these groups had no significant difference (P>0.05).Conclusion The SRT of patients with presbycusis increased and the SRT of male was higher than the females.The average slope of P-I function decreased and the curve moved to right side and became a gradual curve.As hearing loss became more severe,the SRT rose more apparently.

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The Efficacy of Sound Therapy and Conventional Medical Treatment in the Treatment of Chronic Tinnitus: A Meta-analysis

Yang JIANG ; Qingquan HUA ; Kun YANG ; Jie REN ; Feng ZENG ; Jianfei SHENG ; Zhijian ZHANG ; Hongxia GUAN

Journal of Audiology and Speech Pathology.2017;25(6):651-655. doi:10.3969/j.issn.1006-7299.2017.06.024

Objective To compare the efficacy of sound therapy and conventional medical treatment in the treatment of chronic tinnitus.Methods CNKI,Wanfang database,Weipu database (VIP),Chinese biomedical literature database (CBM),Pubmed,Embase,OVID,SciVerse ScienceDirect and Cochrane library were used.The data were retrieved up to May 2017,and the relevant literature was screened according to the inclusion and emission standards.The quality of the literatures were analyzed and the data was extracted.Meta analysis was carried out by using Revman 5.2 software with total effective rate,tinnitus handicap inventory(THI) value and visual analogue scale(VAS) value.Results A total of 16 articles (1 594 patients) were included in the literature,including 14 articles in Chinese and 2 articles in English.The total effective rate in the sound therapy group were 86.42 % (by patients) and 80.50% (by ears),while in conventional medical treatment group were 60.62% (by patients),and 48.10% (by ear),respectively[P<0.01 (by patients),P<0.01 (by ear)].The changes of THI value were analyzed before and after treatment,the difference was statistically significant(P<0.01).The changes of VAS value were analyzed before and after treatment,the difference was statistically significant (P<0.05).Conclusion Compared with conventional medical treatment,sound therapy can significantly improve the clinical efficacy of tinnitus treatment and reduce the symptoms in tinnitus patients.

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The Effects of Nonlinear Frequency Compression on Sound Quality Perception by Hearing-Impaired Listeners

Yanyan YOU ; Xueqing CHEN ; Li XU ; Chao MENG ; Qianqian GUO

Journal of Audiology and Speech Pathology.2017;25(6):640-644. doi:10.3969/j.issn.1006-7299.2017.06.021

Objective To investigate the effects of nonlinear frequency compression (NLFC) on sound quality perception by the Mandarin-speaking subjects with high-frequency hearing loss.Methods Twenty-three listeners with sensorineural hearing loss with no previous experiences of using hearing aids participated in this study.They were all fitted binaurally with Phonak Bolero Q hearing aids.The stimuli,including male voice,female voice,bird chirping,music,and self-voice,were presented in a random order with a custom software via a loudspeaker at 65 dB SPL.Regarding NLFC parameters,cut-off frequency (CF) ranged from 4.9 to 6 kHz and compression ratio (CR) was programed as 1.5.Subjects evaluated the sound quality of the stimulus in loudness,clearness,naturalness and overall preference under the conditions of NLFC-on and NLFC-off.A paired-sample t-test was conducted to assess the group differences in sound quality rating between NLFC on and off conditions.Results Paired test showed significant difference of high-frequency hearing threshold under the condition of NLFC-on and NLFC-off at 6 and 8 kHz(P>0.05).No significant statistical difference was found in subjects' sound quality ratings between NLFC-on and NLFC-off conditions (all P>0.05).Conclusion NLFC technology resulted in no significant impact on sound quality perception for the non-experienced hearing aid users.

Country

China

Publisher

武汉大学人民医院

ElectronicLinks

http://tlxj.chinajournal.net.cn/WKD

Editor-in-chief

E-mail

jasptl@126.com

Abbreviation

Journal of Audiology and Speech Pathology

Vernacular Journal Title

听力学及言语疾病杂志

ISSN

1006-7299

EISSN

Year Approved

2007

Current Indexing Status

Currently Indexed

Start Year

1993

Description

历史沿革【现用刊名:听力学及言语疾病杂志;创刊时间:1993】,该刊被以下数据库收录【中国科学引文数据库(CSCD—2008)】,核心期刊【中文核心期刊(2008)】。

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