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The Report of One Case with the Left Atrial Myxoma Complicated with the Cerebral Embolism.

Kyung Soon LEE ; Hyo Kyun CHO ; Jong Seong KIM

Korean Circulation Journal.1984;14(2):397-401. doi:10.4070/kcj.1984.14.2.397

We report 56 year old female with the left atrial myxoma diagnosed by M mode and 2-D Echocardiography, to be complicated with the cerebral embolism with review of literatures.
Echocardiography ; Female ; Humans ; Intracranial Embolism* ; Middle Aged ; Myxoma*

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Familial Study of Hypertrophic Cardiomyopathy.

Moon Jae KIM ; Hak Yrul KIM ; Woong Ku LEE

Korean Circulation Journal.1984;14(2):385-392. doi:10.4070/kcj.1984.14.2.385

Hypertrophic cardiomyopathy has been a well-known genetical transmitted disease entity with the advance of echocardiography. We have recently experienced a family with hypertrophic cardiomyopathy proved by noninvasive methods including chest x-ray,, electrocardiography and echocardiography. The propositus of this family was a 21 year-old solier who was admitted because of exertional dyspnea during military exercise. Both he and his sister had severely affected hearts with typical echocardiographic findings, asymmetrical septal hypertrophy(ASH) and systolic anterior motion of the anterior mitral leaflet(SAM). The clinical study is reported with the concerned literatures.
Cardiomyopathy, Hypertrophic* ; Dyspnea ; Echocardiography ; Electrocardiography ; Heart ; Humans ; Military Personnel ; Siblings ; Thorax ; Young Adult

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Effect of Combination Therapy of Acebutolol with Hydrochlrothiazide(Sectrazide(R)) on the Serum Lipids of Patients with Essential Hypertension.

Won Sang YOO

Korean Circulation Journal.1984;14(2):377-383. doi:10.4070/kcj.1984.14.2.377

Serial changes of serum lipids were observed in 28 patients with essential hypertension, administered combination regimen of acebutolo 400mg and hydrochlorothiazide 25mf for up to 24 weeks. The results were as follows. 1) Serum total cholesterol and triglyceride level were varied within -6-5 and -2-7% change respectively which were not significant clinically. 2) High density lipoprotein-cholesterol decreased 5% at 6 weeks, 16% and 17% decrease in 12 and 24 weeks respecitively. The changes were more remarkable in the hyperlipidemic patients. 3) Pretreatment average blood pressure of 174/104mmHg lowered to 144/88 at 6 weeks and normalized to 135/86 at 12 weeks. 4) No adverse reaction were observed except mild weakness and indigestion which did not force the discontinuation of drugs. In summary, the fixed-ratio combination of acebutolol and hydrochlorothiazide was excellent in antihypertensive efficacy and patient's compliance, although decrease in high density lipoprotein-cholesterol demand the physician alert to exert vigilance especially in young hypertensives and hyperlipidemic patient to check serum lipids before and during medication, and to change regimen if metabolic derangement is detected in the view point of primary prevention of coronary heart disease.
Acebutolol* ; Blood Pressure ; Cholesterol ; Compliance ; Coronary Disease ; Dyspepsia ; Humans ; Hydrochlorothiazide ; Hypertension* ; Primary Prevention ; Triglycerides

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Clinical Trial on the Hypotensive Effect of Buterazine.

Mi Seon KWON ; Soo Chul OH ; Min Sun PARK ; Heon Kil LIM ; Bang Hun LEE ; Chung Kyun LEE

Korean Circulation Journal.1984;14(2):373-376. doi:10.4070/kcj.1984.14.2.373

The hypotensive effect and side reactions of Buterazine were evaluated in 21 patients with essential hypertension. The results were as follows; 1) Before medication and after 2 and 4 weeks of medication, the over all average systolic and diastolic pressure were 188+/-23/112+/-7, 168+/-13/101+/-17, and 158+/-12/95+/-8mmHg, respectively. After 2 and 4 weeks of medication, the over all average systolic pressure decreased by 20 and 30mmHg(P<0.005, P<0.001), and the over all average diastolic pressure decreased by 11 and 17mmHg(P<0.025, P<0.001), respectively. In 69% of all cases, marked or moderate degree of hypotensive effect was observed. 2) There was no significant changes in heart rates before and after treatment. 3) In 84% of all cases, improvement of symptoms were observed. 4) There was no side effects which required discontinuing the treatment, except 2 cases which discontinued the medication.
Blood Pressure ; Heart Rate ; Humans ; Hypertension

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Clinical Observation on Infective Endocarditis.

Hweung Kon HWANG ; Sung Jun LEE ; Duck Ho HAN ; Kwang Ick KIM ; Oh Yoon KWON ; Hun Kil LIM ; Bang Hun LEE ; Chung Kyun LEE

Korean Circulation Journal.1984;14(2):359-371. doi:10.4070/kcj.1984.14.2.359

A retrospective review of 36 patients with infective endocarditis by strict case definition was performed from 1972 through April of 1984. Male to female ratio was 1:1.25, with mean age of 19.1. Thirty of the 36 patients(83.3%) had the history of predisposing heart diseases: congenital heart disease was most frequent one below the age of 20, rheumatic heart disease between the age of 20-39 and degenerative heart disease above the age of 40. The commonest presenting symptoms were fever, dyspnea, and malaise, and the commonest signs were fever, murmur, and hepatomegaly. Average hemoglobinand hematocrit were 10.1g/dl and 30.8% respectively, showing moderate degree of anemia. White cell count was 11,600+/-5400/mm3 and erythrocyte sedimentation rate was 46+/-18mm/hr. Over four fifths of the patients demonstrated proteinuria and elevated C-reactive protein. Two thirds of the patients showed microscopic hematuria and one third showed positive rheumatoid factor. Eight patients(22.2%) showed arrhythmia and 4(11.1%) showed conduction abnormalities on electrocardiography. The commonest etiologic microorganisms were alpha-hemolytic streptococcus(30.6%) and staphylococcus aureus(22.2%). Abacteremic cases were found in 38.9% of the patients. To compared with alpha-hemolytic streptoccus endocarditis the cases caused by staphylococcus aureus showed the shorter duration of symptoms before admission, the less frequent complication, the higher fever, and the more elevated white cell counts. To penicillin, alpha-hemolytic streptococcus was sensitive in most cultures and staphylococcus arueus was resistant in half of them, and to aminoglycosides vice versa. To cefazolin, both microorganisms were sensitive in most cultures. In 18 of 24(75%) patients vegetation was visualized by echocardiography. The most frequent site of involvement was the mitral valve. And in vegetation detected group complication rate by embolism was found to be higher. The common complications were congestive heart gailure in 24(66.75%), embolism in 8(22.2%), and metastatic infection in 6(16.7%). The mortality rate of infective endocarditis was 25%, and the causes of death were cerebral embolism in 3(8.3%), septic septic shock in 3(8.3%), congestive heart failure in 2(5.6%), and mycotic aneurysmal rupture in 1(2.8%). Conclusively in infective endocarditis the author observed the increasing prevalence of degenerative heart disease as a prdisposing heart disease and increasing incidence of staphylococcus aureus as a causative microorganism. Adn the differences of clinical characteristics between staphylococcus ureus and alpha-hemolytic streptococcus endocarditis would be helpful in diagnosis and treatment of infective endocarditis as well as recognition of prognosis.
Aminoglycosides ; Anemia ; Aneurysm, Infected ; Arrhythmias, Cardiac ; Blood Sedimentation ; C-Reactive Protein ; Cause of Death ; Cefazolin ; Cell Count ; Diagnosis ; Dyspnea ; Echocardiography ; Electrocardiography ; Embolism ; Endocarditis* ; Estrogens, Conjugated (USP) ; Female ; Fever ; Heart ; Heart Defects, Congenital ; Heart Diseases ; Heart Failure ; Hematocrit ; Hematuria ; Hepatomegaly ; Humans ; Incidence ; Intracranial Embolism ; Male ; Mitral Valve ; Mortality ; Penicillins ; Prevalence ; Prognosis ; Proteinuria ; Retrospective Studies ; Rheumatic Heart Disease ; Rheumatoid Factor ; Rupture ; Shock, Septic ; Staphylococcus ; Staphylococcus aureus ; Streptococcus

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Clinical Study of Mucocutaneous Lymph Node Syndrome.

Young Choon WOO ; Sang Hoon HONG ; Soo Un PARK ; Yang Soo KIM ; Kyung Ja LEE ; Ki Yang RYOO

Korean Circulation Journal.1984;14(2):349-357. doi:10.4070/kcj.1984.14.2.349

We observed clinically 27 cases of MCLS at this pediatric department from Jan. 1980 to Jun. 1984 and following result were obtained. 1) The peak incidence of these cases was from 1 year to 4 year of age(74%) and male children were affected more frequently than female children at a ratio of 2.4:1. 2) Clinical manifestation of MCLS were high fever, conjunctioval injection, changes of oral cavity and lips, erythematous rash, cervical lymphadenopathy, changes of the extremities. 3) The abnormal laboratory findings include leukocytosis, slight anemia, raised ESR, positive CRP, mild proteinuria or pyeuria, and slight increase of serum transaminase and LDH. 4) The abnormal cardiovascular findings were as follow : heart murmur in 15% cardiomegaly in 19% by chest roentgenogram, electrocardiographic abnormalities in 59%, suspicious aneurysmal dilatation and coronary aneurysm by 2-D echocardiogram in 11%. 5) Aspirin was given in acute febrile stage as antiinflammatory dose(100mg/kg/day), in non-febrile convalescent stage to maintain low dose of aspirin(20-30mg/kg/day) as antiplatelet effect, and completely recovered in all cases without andy complication.
Anemia ; Aneurysm ; Aspirin ; Cardiomegaly ; Child ; Coronary Aneurysm ; Dilatation ; Electrocardiography ; Exanthema ; Extremities ; Female ; Fever ; Heart Murmurs ; Humans ; Incidence ; Leukocytosis ; Lip ; Lymphatic Diseases ; Male ; Mouth ; Mucocutaneous Lymph Node Syndrome* ; Proteinuria ; Thorax

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A Clinical Review on Cor Pulmonale.

Joon Gil CHO ; Kyung Hee WON ; Hong Soon LEE ; Hak Choong LEE

Korean Circulation Journal.1984;14(2):343-347. doi:10.4070/kcj.1984.14.2.343

A clinical review was made on 48 cases with cor pulmonale who were admitted to medical department, National Medical Center, between 1973 and 1982, and the results were as follows : 1) Teh age of subjects ranged from 26 to 88, and their mean was 51. male to female ratio was 1.6:1 and majority of them were in their 6th and 7th decade. 2) COPD was the most common cause of cor pulmonale but pulmonary tuberculosis had also a considerable portion. Less commonly it was caused by chest deformity which was mainly from spine tuberculosis and kyphoscoliosis. 3) Almost all patients were admitted with over heart failure. 4) Laboratory features showed indirect evidence of heart failure and pulmonary hypertension in chest X-ray films, RVH patterns in EKG and hypoxia and hypertcapnea with metabolic compensation in arterial gas analysis. 5) The case fatality rate was one-forth and that from kyphoscoliosis was especially high(80%).
Anoxia ; Compensation and Redress ; Congenital Abnormalities ; Electrocardiography ; Female ; Heart Failure ; Humans ; Hypertension, Pulmonary ; Male ; Mortality ; Pulmonary Disease, Chronic Obstructive ; Pulmonary Heart Disease* ; Spine ; Thorax ; Tuberculosis ; Tuberculosis, Pulmonary ; X-Ray Film

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Clinical Observation of Acute Myocardial Infarction.

Sang Yong LEE ; Jin Ho KIM ; Yun Sik YANG ; Hyung Il MOON ; Jong Sik KANG

Korean Circulation Journal.1984;14(2):333-342. doi:10.4070/kcj.1984.14.2.333

A Clinical study was done on 90 cases of acute myocardial infarction admitted to Busan Wallace Memorial Baptist Hospital from January, 1977 to Febuary, 1983. The following results have been obtained. 1) The ratio of male to female was 2.2:1. The most age group were 5th decades(35.6%) and over 5th decades(5th decades and 6th decades) were two-thirds of all age group. And annual incidency were increasing tendencies, in 1980-1982 than 1977-1979. 2) Between the preceding diseases and the risk factors, the most common cause was the smoking (60%). And other associated diseases and factors were hypertension(54.4%), hypercholesterolemia (43.8%), hyperlipidemia(51.4%) and angina pectoris (34.4%). 3) The most common inducing factor was physical exertion(33.3%). And others were emotional stress(23.3%), alcohol drinking(10%), rest and sleeping(5.6%). 4) The major symptoms of acute myocardial infarction were precordial or epigastric pain(96.7%), dyspnea(53.3%), radiating chest pain (51.7%) and painless infarction(3.3%). 5) On laboratory data, there were leukocytosis in 50.5% increased SGOT in 68.6%, increased serum LDH in 75.9% and cardiomegaly in chest x-ray film were 82 percents. 6) The ratio between the anterior and inferior infarction on EKG was 1.9:1. 7) When admission, normal sinus rhythms on EKG were 59 percents. And the common associated electrocardiographic abnormalities were ventricular premature beat (23.6%), atrial fibrillation(15.7%), first degree A-V block (15.7%), left ventricular hypertrophy(15.7%). The most common abnormality was ventricular premature beat(23.6%). 8) The mortality rate of acute myocardial infarction was 10 percents. The causes of death were heart failure(33.3%), ventricular arrhythmia(33.3%), sudden death (22.2%) and cardiogenic shock(11.1%).
Angina Pectoris ; Aspartate Aminotransferases ; Busan ; Cardiac Complexes, Premature ; Cardiomegaly ; Cause of Death ; Chest Pain ; Death, Sudden ; Electrocardiography ; Female ; Heart ; Humans ; Hypercholesterolemia ; Infarction ; Leukocytosis ; Male ; Mortality ; Myocardial Infarction* ; Protestantism ; Risk Factors ; Smoke ; Smoking ; Thorax ; X-Ray Film

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Epidemiological Studies on Geriatric Hypertension in Korea.

Hae Joo KIM ; Young Ahn AHN ; Hyun II CHUN ; Jae Seong LEE ; Shin Chae HUH ; Sun Tae KIM

Korean Circulation Journal.1984;14(2):327-332. doi:10.4070/kcj.1984.14.2.327

A total of 4757 apparently healthy aged persons over 65 years of age was surveyed for geriatric hypertension. A single blood pressure measurement was taken in the sitting position. Mean systolic blood pressure rose significantly with age in female but didn't in male and mean diastolic blood pressure didn't change with age in both sex. The prevalence of pure systolic hypertension, i.e., a systolic blood pressure greater than or equal to 160 mmhg and a diastolic blood pressure less than 95mmhg, increased with age. The prevalence was slighty lower for female than it was for male, being 7.0% for female and 8.0% for male. The prevalence of classical hypertension-defined as diastolic blood pressure greater than or equal to 95mmhg - was 42.7% for female and 48.2% for male and it rose with age in female. The prevalence of both pure systolic and classical hypertension was 49.7% for female and 56.1% for male.
Blood Pressure ; Epidemiologic Studies* ; Female ; Humans ; Hypertension* ; Korea* ; Male ; Prevalence

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Radiological Findings of Vascular Involvement in Behcet's Disease.

Jae Hyung PARK ; Chong Bum LEE ; Man Chung HAN ; Sung Jae CHOI

Korean Circulation Journal.1984;14(2):309-314. doi:10.4070/kcj.1984.14.2.309

Angiographic findings were analysed in 11 cases of Behcet'sdisease which was diagnosed clinically in Seoul national University Hospital from July 1982 to June 1983. Arterial involvement was noted in 5 cases and venous involvement in 6 cases respectively. Arterial aneurysm and occlusion were arteriographic findings. Arterial aneurysm was noted at large arteries in all 5 cases and multifocal involvement was noted in 4 cases. Characteristic finding of arterial involvement was protruding saccular aneurysm. Venous involvement was thrombotic occlusion of deep veins in iliac, femoral and tibial areas in all 6 cases. Behcet's disease should be differentiated whenever these arterial or venous angiographic findings are revealed in a young adult.
Aneurysm ; Arteries ; Humans ; Seoul ; Veins ; Young Adult

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