Journal of Cardiovascular Imaging.2024;32(1):26-. doi:10.1186/s44348-024-00033-2
Journal of Cardiovascular Imaging
2002 (v1, n1) to Present ISSN: 1671-8925
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To see those not to be seen: cardiac uptake on noncardiac imaging
Journal of Cardiovascular Imaging.2024;32(1):32-. doi:10.1186/s44348-024-00024-3
Journal of Cardiovascular Imaging.2024;32(1):28-. doi:10.1186/s44348-024-00006-5
Usefulness and importance of echocardiography in the diagnosis of pediatric pulmonary hypertension
Journal of Cardiovascular Imaging.2024;32(1):33-. doi:10.1186/s44348-024-00022-5
Journal of Cardiovascular Imaging.2024;32(1):31-. doi:10.1186/s44348-024-00034-1
Journal of Cardiovascular Imaging.2024;32(1):38-. doi:10.1186/s44348-024-00042-1
Journal of Cardiovascular Imaging.2024;32(1):36-. doi:10.1186/s44348-024-00041-2
Delayed onset of hypertrophic cardiomyopathy in a 61‑year‑old male patient with MYBPC3 mutation
Journal of Cardiovascular Imaging.2024;32(1):24-. doi:10.1186/s44348-024-00009-2
Journal of Cardiovascular Imaging.2024;32(1):39-. doi:10.1186/s44348-024-00037-y
Background:
Aortic valve sclerosis (AVS) shares risk factors with atherosclerosis. However, the relationship between AVS progression with cardiovascular (CV) risk has not been researched. This study investigates CV outcomes according to progression of AVS.
Methods:
This study included 2,901 patients with AVS (irregular leaflet thickening and peak aortic jet veloc‑ ity < 2 m/sec) who underwent serial echocardiograms at least 1 year apart during 2011–2020. The primary outcome was defined as CV death, myocardial infarction, stroke, or revascularization.
Results:
During a median follow-up period of 3.9 years, 439 of 2,901 AVS patients (15.1%) progressed to mild or greater aortic stenosis. Patients with progression were older and more likely to have atrial fibrillation than those without. In a stepwise regression, age (odds ratio [OR] per 1-year increase, 1.04; 95% confidence interval [CI], 1.01– 1.07), peripheral artery disease (OR, 9.07; 95% CI, 3.12–26.4), and left ventricular mass index (OR per 1-g/m 2 increase, 1.01; 95% CI, 1.00–1.02) were associated with AVS progression. Over a median of 6.3 years, the primary outcome occurred in 858 of 2,901 patients (29.6%). Patients with progression had higher frequency of CV death, myocardial infarction, stroke, or revascularization than those without progression (P < 0.0001). In Cox proportional hazards regres‑ sion, AVS progression (hazard ratio, 1.33; 95% CI, 1.10–1.61) was a significant determinant of CV mortality.
Conclusions
The progression to aortic stenosis in AVS patients is an independent risk factor for CV mortality. These findings suggest that patients with AVS progression may benefit from stricter CV risk monitoring.
Journal of Cardiovascular Imaging.2024;32(1):34-. doi:10.1186/s44348-024-00039-w
Country
Republic of Korea
Publisher
Korean Society of Echocardiography
ElectronicLinks
https://e-jcvi.orgEditor-in-chief
Seong Hwan Kim
e-jcvi@ksecho.org
Abbreviation
J Cardiovasc Imaging
Vernacular Journal Title
ISSN
2586-7210
EISSN
2586-7296
Year Approved
2007
Current Indexing Status
Currently Indexed
Start Year
2018
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