Philippine Journal of Reproductive Endocrinology and Infertility 2018;15(2):54-62

"Double Trouble": A case of precocious puberty with concomitant malignant gluteal mass

Pisces Jean Alunes-Chog-ap 1 ; Thea Zola B. Cariaga 1

Affiliations

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Keywords

Clitoromegaly; Malignant round cell tumor

Country

Philippines

Language

English

Abstract

Precocious puberty is the appearance of physical and hormonal signs of pubertal development at an earlier age than is considered normal. The causes may range from a variant of normal development to pathologic conditions such as glands that function abnormally early in life. This is a case of a seven year old female with clitoromegaly, early menarche and a gluteal mass accompanied by elevated 17-hydoxyprogesterone and decreased level of cortisol which supports the diagnosis of congenital adrenal hyperplasia. Gluteal mass cytological features are consistent with a malignant round cell tumor.