Journal of Pharmaceutical Practice 2023;41(6):335-340

doi:10.12206/j.issn.2097-2024.202204111

Advances in the treatment of diabetic ulcers by Chinese herbal extracts

Hanzhi LU 1 ; Yi WANG 1 ; Dongjie GUO 1 ; Wanjun GUO 1 ; Jianyong ZHU 1 ; Fulun LI 1

Affiliations

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Keywords

Chinese herbal medicine; extracts; diabetic ulcers; mechanism of action

Country

China

Language

Chinese

Abstract

Skin ulcers are the most prevalent consequence of diabetes mellitus, and people with diabetic ulcers have a substantially greater death risk than those who do not have ulcers. Herbal medications have gained wide concern in recent years due to their multi-component, multi-target, and multi-pathway synergistic therapeutic effects. Clinical trials have demonstrated the safety and efficacy of herbal treatments in diabetic refractory ulcers. To systematically evaluate the healing effect of herbs on diabetic wounds, a literature search was conducted, the mechanism of action of 15 herbal extracts in promoting diabetic wound healing were reviewed, and the classification based on traditional Chinese medicine theory was discussed, which could provide a reference for the precise treatment and exploitation of herbal medicines for diabetic ulcers.