Organ Transplantation 2022;13(5):611-
doi:10.3969/j.issn.1674-7445.2022.05.010
Predictive values of ALBI and EZ-ALBI scores for early survival of recipients with liver failure after liver transplantation
Chengkai YANG 1 ; Jiamian XU ; Huaxiang WANG ; Lizhi LYU ; Yi JIANG ; Aiping WU
Affiliations
Keywords
Liver transplantation; Liver failure; Albumin-bilirubin (ALBI) score; Easy albumin-bilirubin (EZ-ALBI) score; Receiver operating characteristic curve; Risk factor; Child-Turcotte-Pugh (CTP) score; Model for end-stage liver disease (MELD) score
Country
China
Language
Chinese
Abstract
Objective To evaluate the predictive values of albumin-bilirubin (ALBI) and easy albumin-bilirubin (EZ-ALBI) scores for early survival (postoperative 3 months) of recipients with liver failure after liver transplantation. Methods Clinical data of 137 recipients diagnosed with liver failure and underwent liver transplantation were retrospectively analyzed. The optimal cut-off values of preoperative ALBI, EZ-ALBI and MELD scores to predict early survival of recipients with liver failure after liver transplantation were determined by the area under the receiver operating characteristic (ROC) curve. The risk factors of early death of recipients with liver failure after liver transplantation were identified by univariate and multivariate Cox regression analyses. The effects of different ALBI and EZ-ALBI levels upon early prognosis of recipients with liver failure after liver transplantation were analyzed. Results The optimal cut-off values of ALBI, EZ-ALBI and MELD scores were 0.21, -19.83 and 24.36, and the AUC was 0.706, 0.697 and 0.686, respectively. Univariate Cox regression analysis showed that preoperative alanine aminotransferase(ALT)≥50 U/L, aspartate aminotransferase(AST)≥60 U/L, ALBI score≥0.21 and EZ-ALBI score≥-19.83 were the risk factors for early postoperative death of recipients with liver failure after liver transplantation (all
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