Clinical and Experimental Reproductive Medicine  2014;41(3):137-139

doi:10.5653/cerm.2014.41.3.137

An effective method for improving outcomes in patients with a fertilization defect.

Hye Jin YOON 1 ; Hyung Jun KIM ; In Hee BAE ; Soo Jin CHAE ; San Hyun YOON ; Won Don LEE ; Jin Ho LIM

Affiliations

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Keywords

Artificial oocyte activation; Intracytoplasmic morphologically selected sperm injection; Recurrent implantation failures

Country

Republic of Korea

Language

English

Abstract

The effect of artificial oocyte activation (AOA) with a calcium ionophore on intracytoplasmic morphologically selected sperm injection (IMSI) was examined in patients with histories of repeated failed implantation attempts. Four singleton pregnancies and one twin pregnancy were obtained after embryos transfer (5/14, 35.7%). Therefore, AOA combined with IMSI can be considered an option for cycles with a fertilization defect and recurrent implantation failures.