Cancer Research and Treatment  2012;44(2):142-145

Metastatic Skin Lesions on Lower Extremities in a Patient with Recurrent Serous Papillary Ovarian Carcinoma: A Case Report and Literature Review.

Moon Kyung KIM 1 ; Seo Hee KIM ; Yoo Young LEE ; Chel Hun CHOI ; Tae Joong KIM ; Jeoung Won LEE ; Je Ho LEE ; Duk Soo BAE ; Byoung Gie KIM

Affiliations

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Keywords

Drug therapy; Neoplasm metastasis; Ovarian neoplasms; Palliative care; Skin neoplasms

Country

Republic of Korea

Language

English

Abstract

Clinical observation of skin metastasis in ovarian cancer cases is relatively uncommon. And distant metastatic skin lesions including the extremities are much rarer still as most metastatic skin lesions are located in the skin in the abdominal wall adjacent to where the primary ovarian tumors exist. We report the case of a 60-year-old woman who presented skin lesions on both lower extremities as a consequence of the metastasis of serous papillary adenocarcinoma of the ovary. She presented with erythematous and painful cutaneous nodules on both upper legs and in the inguinal area 42 months after initial diagnosis of ovarian cancer. Skin biopsy revealed metastasis of adenocarcinoma in the dermis. She was treated with surgical excision and systemic chemotherapy. Literature review has suggested that a combined modality approach including surgical excision and chemotherapy may be useful in the management of skin metastases due to ovarian cancer.