Kidney Research and Clinical Practice  2013;32(3):134-137

Membranous glomerulonephritis in a patient with myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia.

Kwang Il KO 1 ; Mi Jung LEE ; Fa Mee DOH ; Hyang Mo KOO ; Chan Ho KIM ; Dong Ho SHIN ; Hyung Jung OH ; Seung Hyeok HAN ; Shin Wook KANG ; Kyu Hun CHOI ; Tae Hyun YOO

Affiliations

+expand

Keywords

Membranous glomerulonephritis; Myelodysplastic syndrome; Nephrotic syndrome; Refractory cytopenia with multilineage dysplasia

Country

Republic of Korea

Language

English

Abstract

A 74-year-old woman presented with edema in the lower extremities. Laboratory tests revealed anemia, thrombocytopenia, hypoalbuminemia, hypercholesterolemia, and nephrotic-range proteinuria. Myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia (MDS-RCMD) was confirmed by bone marrow biopsy. Renal biopsy demonstrated membranous glomerulonephritis (MGN), stage I. Based on these clinicopathologic results, she was diagnosed as having MGN with MDS-RCMD. This is a rare case report of MGN in a parient with MDS-RCMD featuring nephrotic syndrome.