Yonsei Medical Journal  2002;43(2):267-270

doi:10.3349/ymj.2002.43.2.267

Successful Cyclophosphamide Therapy in Recurrent Eosinophilic Colitis Associated with Hypereosinophilic Syndrome.

Ju Hee LEE 1 ; Jin Woo LEE ; Cheol Soon JANG ; Eun Sang KWON ; Hyo Young MIN ; Seok JEONG ; Kye Sook KWON ; Don Haeng LEE ; Hyeon Geun CHO ; Pum Soo KIM ; Hyung Gil KIM ; Yong Woon SHIN ; Young Soo KIM

Affiliations

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Keywords

Hypereosinophilic syndrome; eosinophilic colitis; cyclophosphamide

Country

Republic of Korea

Language

English

Abstract

Eosinophilic colitis is a relatively rare complication of hypereosinophilic syndrome which is characterized by abdominal pain and bloody diarrhea and is usually treated with steroids and hydroxyurea. However, no standard regimen exists in cases of intractable disease despite several treatment attempts with Interferon- alpha, cyclosporin, etoposide, and vincristine, etc. We here report a case of a 43-year-old woman with recurrent eosinophilic colitis as a complication of hypereosinophilic syndrome who was successfully treated with cyclophosphamide.