PURPOSE: This study was conducted to identify health promotion lifestyle (HPL), farmers' syndrome and related factors of workers in agricultural industry. METHODS: A total of 454 agricultural workers were selected through convenient sampling. Data were collected from July 1 to August 10, 2009. Data analysis included frequency, t-test, ANOVA, Scheffe test, and stepwise multiple regression using SPSS/WIN 17.0. RESULTS: 1. The mean score of HPL was 3.30 and the prevalence of farmers' syndrome was 29.3%. 2. Analysis of farmers' syndrome showed there were statistically significant differences for gender, age, sleeping time, perceived health status, breakfast and exercise. 3. Gender, age, perceived health status, breakfast and exercise were identified as variables influencing the farmers' syndrome. CONCLUSION: This study suggested that we should develop health promotion programs for workers of agricultural industry considering these results.